| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jeong-Ah Shin, Yeong Deok Kwon, Oh-Hee Kwon, Heung Shick Lee, Pil Ki. 5-aminolevulinic acid biosynthesis in Escherichia coli coexpressing NADP-dependent malic enzyme and 5-aminolevulinate synthase. Journal of microbiology and biotechnology. vol 17. issue 9. 2008-03-20. PMID:18062242. |
2.3.1.37), which mediates the pyridoxal phosphate-dependent condensation of glycine and succinyl-coa, encoded by the rhodobacter sphaeroides hema gene, enables escherichia coli strains to produce ala at a low level. |
2008-03-20 |
2023-08-12 |
Not clear |
| Jeong-Ah Shin, Yeong Deok Kwon, Oh-Hee Kwon, Heung Shick Lee, Pil Ki. 5-aminolevulinic acid biosynthesis in Escherichia coli coexpressing NADP-dependent malic enzyme and 5-aminolevulinate synthase. Journal of microbiology and biotechnology. vol 17. issue 9. 2008-03-20. PMID:18062242. |
the concentration of ala was two times greater in cells coexpressing maeb and hema than in cells expressing hema alone under anaerobic conditions with medium containing glucose and glycine. |
2008-03-20 |
2023-08-12 |
Not clear |
| b' Am\\xc3\\xa9lie Deglaire, Paul J Moughan, Shane M Rutherfurd, C\\xc3\\xa9cile Bos, Daniel Tom\\xc3\\xa. Feeding dietary peptides to growing rats enhances gut endogenous protein flows compared with feeding protein-free or free amino acid-based diets. The Journal of nutrition. vol 137. issue 11. 2008-03-12. PMID:17951481.' |
semisynthetic diets containing enzyme-hydrolyzed casein (hc; 11%) or a free aa mixture devoid of asp and ser (a1) or gly and ala (a2) were formulated to have similar aa compositions except for the excluded aa and similar dietary electrolyte balances (na(+)+k(+)-cl(-)). |
2008-03-12 |
2023-08-12 |
rat |
| b' Am\\xc3\\xa9lie Deglaire, Paul J Moughan, Shane M Rutherfurd, C\\xc3\\xa9cile Bos, Daniel Tom\\xc3\\xa. Feeding dietary peptides to growing rats enhances gut endogenous protein flows compared with feeding protein-free or free amino acid-based diets. The Journal of nutrition. vol 137. issue 11. 2008-03-12. PMID:17951481.' |
endogenous flows of asp and ser or gly and ala did not differ (p > 0.05) in any of the intestinal sections between rats fed pf and a1 or pf and a2, respectively, except in the stomach where ser flow was greater for rats fed a1. |
2008-03-12 |
2023-08-12 |
rat |
| Karin Juleniu. NetCGlyc 1.0: prediction of mammalian C-mannosylation sites. Glycobiology. vol 17. issue 8. 2008-03-06. PMID:17494086. |
we also find a clear preference in position +1, where a small and/or polar residue (ser, ala, gly, and thr) is preferred and a phe or a leu residue discriminated against. |
2008-03-06 |
2023-08-12 |
human |
| Bokun Cheng, Elena P Sorokin, Yuk-Ching Tse-Din. Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I. Nucleic acids research. vol 36. issue 3. 2008-03-04. PMID:18096618. |
while the gly to ala substitution allowed both dna cleavage and religation, other mutations abolished dna cleavage. |
2008-03-04 |
2023-08-12 |
Not clear |
| Z H Kudzin, R Depczyński, M H Kudzin, J Drabowic. 1-(N-chloroacetylamino)-alkylphosphonic acids - synthetic precursors of phosphonopeptides. Amino acids. vol 34. issue 1. 2008-02-25. PMID:17111101. |
general procedures of n-chloroacetylation of the representative 1-aminoalkylphosphonic acids (gly(p), ala(p), val(p), pgly(p) and phe(p)) are described. |
2008-02-25 |
2023-08-12 |
Not clear |
| Yongki Shim, Shankararaman Chella. Steric and electrostatic interactions govern nanofiltration of amino acids. Biotechnology and bioengineering. vol 98. issue 2. 2008-02-25. PMID:17335060. |
the removals of five monoprotic (ala, val, leu, gly, and thr), one diprotic (asp), and one dibasic (arg) amino acids in a range of permeate fluxes, feed ph values, and ionic strengths were analyzed using a phenomenological model of membrane transport. |
2008-02-25 |
2023-08-12 |
Not clear |
| Maï Panchal, Noureddine Lazar, Noeli Munoz, Christine Fahy, Christine Clamagirand, Jean-Paul Brouard, Lionel Dubost, Paul Cohen, Noureddine Brakch, Mohamed Rhola. Clearance of amyloid-beta peptide by neuronal and non-neuronal cells: proteolytic degradation by secreted and membrane associated proteases. Current neurovascular research. vol 4. issue 4. 2008-02-07. PMID:18045149. |
by using a combination of the liquid chromatography/on-line mass spectrometry, we demonstrate that: (i)-the membrane associated protease(s) hydrolizes abeta40 essentially at lys(28) gly(29), phe(19) phe(20) and val(18) phe(19) bonds; and (ii)-the secreted protease(s) cleaves the generating fragments abeta (1-28), abeta (1-19), abeta (1-18) at his(14) gln(15) bond and also abeta (1-28) at phe(20) ala(21) and asp(23) val(24) sites. |
2008-02-07 |
2023-08-12 |
Not clear |
| Benjamin Haffemayer, Eric Richard, Hélène Mattras, Jacky Mari. Functional role of the conserved proline in helix 6 of the human bradykinin B2 receptor. Biochemical and biophysical research communications. vol 366. issue 4. 2008-02-05. PMID:18096516. |
using mutagenesis, we show that pro258 is required for normal trafficking of the receptor to the plasma membrane and that mutation of pro258 to ala or leu but not gly, enhances bk efficacy to induce receptor activation. |
2008-02-05 |
2023-08-12 |
human |
| Lang Tian, Juan Liao, Jian-wen Li, Wan-rong Zhou, Xia-lan Zhang, Hong-ning Wan. Isolation and identification of a non-haemagglutinating strain of rabbit hemorrhagic disease virus from China and sequence analysis for the VP60 Gene. Virus genes. vol 35. issue 3. 2008-01-29. PMID:17705093. |
from the experiment, it's concluded that, the "whn-1" strain is probably an antigenic variant of "rhdva", and the 3 amino acids of phe (304), ala (305), ser (309), and 5 amino acids of gly (359), asn (365), ala (369), ala (370), asn (386), located in p2 region in the vp60 protein, probably played an important role in the haemagglutination activity. |
2008-01-29 |
2023-08-12 |
rabbit |
| Mitsuru Haruki, Masaki Tanaka, Takehiko Motegi, Takashi Tadokoro, Yuichi Koga, Kazufumi Takano, Shigenori Kanay. Structural and thermodynamic analyses of Escherichia coli RNase HI variant with quintuple thermostabilizing mutations. The FEBS journal. vol 274. issue 22. 2008-01-29. PMID:17944939. |
a combination of five thermostabilizing mutations, gly23-->ala, his62-->pro, val74-->leu, lys95-->gly, and asp134-->his, has been shown to additively enhance the thermostability of escherichia coli rnase hi [akasako a, haruki m, oobatake m & kanaya s (1995) biochemistry34, 8115-8122]. |
2008-01-29 |
2023-08-12 |
Not clear |
| Anand Anbarasu, Sudha Anand, Sethumadhavan Ra. Investigations on unconventional hydrogen bonds in RNA binding proteins: the role of CH...O=C interactions. Bio Systems. vol 90. issue 3. 2008-01-22. PMID:17555865. |
the secondary structure preference analysis of ch...o=c interacting residues showed that, arg, gln, glu and tyr preferred to be in helix, while ala, asp, cys, gly, ile, leu, lys, met, phe, trp and val preferred to be in strand conformation. |
2008-01-22 |
2023-08-12 |
Not clear |
| J Michael Conlon, Rokaya Al-Kharrge, Eman Ahmed, Haider Raza, Sehamuddin Galadari, Eric Condamin. Effect of aminoisobutyric acid (Aib) substitutions on the antimicrobial and cytolytic activities of the frog skin peptide, temporin-1DRa. Peptides. vol 28. issue 10. 2008-01-22. PMID:17767978. |
aib substitutions at gly(4), asn(8), and ala(10) increased both % helicity, determined in methanol solution, and hydrophobicity resulting in increases in both antimicrobial potencies and toxicities against the mammalian cells. |
2008-01-22 |
2023-08-12 |
human |
| Rae-Hyun Koh, Hong-Gyu Son. Effects of application of Rhodopseudomonas sp. on seed germination and growth of tomato under axenic conditions. Journal of microbiology and biotechnology. vol 17. issue 11. 2008-01-18. PMID:18092464. |
rhodopseudomonas kl9 increased 123.5% and 54% of the root and shoot lengths of germinated seedling, respectively, treated with 15 mm glycine and succinate, precursors of ala. |
2008-01-18 |
2023-08-12 |
Not clear |
| Todd W Geders, Liangcai Gu, Jonathan C Mowers, Haichuan Liu, William H Gerwick, Kristina Håkansson, David H Sherman, Janet L Smit. Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching. The Journal of biological chemistry. vol 282. issue 49. 2008-01-17. PMID:17928301. |
ala(78) and gly(118) form an oxyanion hole in the active site that includes only three polar side chains as potential catalytic residues. |
2008-01-17 |
2023-08-12 |
Not clear |
| Remko A Bakker, Aldo Jongejan, Kamonchanok Sansuk, Uli Hacksell, Henk Timmerman, Mark R Brann, Dave M Weiner, Leonardo Pardo, Rob Leur. Constitutively active mutants of the histamine H1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class A G protein-coupled receptors. Molecular pharmacology. vol 73. issue 1. 2008-01-16. PMID:17959710. |
this approach identified position 6.40 in tm 6 as a "hot spot" because mutation of ile6.40(420) either to glu, gly, ala, arg, lys, or ser resulted in highly active cam h(1)rs, for which almost no histamine-induced receptor activation response could be detected. |
2008-01-16 |
2023-08-12 |
Not clear |
| Remko A Bakker, Aldo Jongejan, Kamonchanok Sansuk, Uli Hacksell, Henk Timmerman, Mark R Brann, Dave M Weiner, Leonardo Pardo, Rob Leur. Constitutively active mutants of the histamine H1 receptor suggest a conserved hydrophobic asparagine-cage that constrains the activation of class A G protein-coupled receptors. Molecular pharmacology. vol 73. issue 1. 2008-01-16. PMID:17959710. |
mutation of the asparagine cage into ala or gly, removing the interfering bulky constraints, increases the constitutive activity of the receptor. |
2008-01-16 |
2023-08-12 |
Not clear |
| Noémi I Jakab, Béla Gyurcsik, Tamás Körtvélyesi, Ilze Vosekalna, Jan Jensen, Erik Larse. Design of histidine containing peptides for better understanding of their coordination mode toward copper(II) by CD spectroscopy. Journal of inorganic biochemistry. vol 101. issue 10. 2008-01-15. PMID:17628687. |
the replacement of a gly residue with the chiral ala amino acid allowed us to gain decisive information on the solution structure of the complexes by cd spectroscopy. |
2008-01-15 |
2023-08-12 |
Not clear |
| Crystal Ying Wang, Yajun Wang, Amy Ho Yan Kwok, Frederick C Leun. Identification of two novel chicken GHRH receptor splice variants: implications for the roles of aspartate 56 in the receptor activation and direct ligand receptor interaction. The Journal of endocrinology. vol 195. issue 3. 2008-01-15. PMID:18000314. |
to substantiate this hypothesis, using site-directed mutagenesis, two receptor mutants with replacement of asp(56) by ala or gly were generated. |
2008-01-15 |
2023-08-12 |
human |