Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xue Cheng, Haiping Zhao, Feng Yan, Zhen Tao, Rongliang Wang, Ziping Han, Guangwen Li, Yumin Luo, Xunming J. Limb remote ischemic post-conditioning mitigates brain recovery in a mouse model of ischemic stroke by regulating reactive astrocytic plasticity. Brain research. vol 1686. 2019-04-19. PMID:29462606. |
moreover, the proportion of astrocyte subtypes was adjusted by ripc treatment, demonstrated by decreased expression of the fibrous type (glial fibrillary acidic protein, gfap) and increased expression of the protoplasmic type (glutamine synthetase, gs) in the ipsilateral side of the mouse brain at 14 d after cerebral ischemia-reperfusion. |
2019-04-19 |
2023-08-13 |
mouse |
Cai Zhang, Yong-Ping Zhang, Yu-Yu Li, Bai-Ping Liu, Hao-Yin Wang, Kang-Wei Li, Shannon Zhao, Cai Son. Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat. Behavioural brain research. vol 356. 2019-04-16. PMID:30003978. |
meanwhile, cums inhibited the expressions of astrocyte marker glial fibrillary acidic protein (gfap), brain-derived neurotrophic factor (bdnf) and trkb. |
2019-04-16 |
2023-08-13 |
rat |
Arden G Vanderwall, Shahani Noor, Melody S Sun, Jacob E Sanchez, Xuexian O Yang, Lauren L Jantzie, Nikolaos Mellios, Erin D Milliga. Effects of spinal non-viral interleukin-10 gene therapy formulated with d-mannose in neuropathic interleukin-10 deficient mice: Behavioral characterization, mRNA and protein analysis in pain relevant tissues. Brain, behavior, and immunity. vol 69. 2019-04-15. PMID:29113923. |
similarly, dm/pdna-il-10 treatment decreases immunoreactivity for the astrocyte activation marker gfap in lumbar spinal cord dorsal horn. |
2019-04-15 |
2023-08-13 |
mouse |
Mohammad M Al-Qattan, Mervat M Abd-Alwahed, Medhat K Shie. Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 28. issue 12. 2019-04-15. PMID:30501829. |
effect of tgfβ1 and nag on astrocyte cultures: a study of astrocyte proliferation and the expression of gfap, cspg4, s100b and il-6. |
2019-04-15 |
2023-08-13 |
Not clear |
Mohammad M Al-Qattan, Mervat M Abd-Alwahed, Medhat K Shie. Effect of TGFβ1 and nAG on Astrocyte Cultures: A Study of Astrocyte Proliferation and the Expression of GFAP, CSPG4, S100B and IL-6. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. vol 28. issue 12. 2019-04-15. PMID:30501829. |
to determine the effects of tgfβ1 and an anti-scar protein nag on normal (un-injured) 3-d astrocyte cultures with special emphasis on astrocyte proliferation, and the expression of gfap, cspg4, s100b, and il-6. |
2019-04-15 |
2023-08-13 |
Not clear |
Shahidee Zainal Abidin, Sze-Zheng Fam, Chan-Eng Chong, Syahril Abdullah, Pike-See Cheah, Norshariza Nordin, King-Hwa Lin. miR-3099 promotes neurogenesis and inhibits astrogliogenesis during murine neural development. Gene. vol 697. 2019-04-11. PMID:30769142. |
in contrast, gene related to astrocyte markers (gfap, s100β and slc1a3) were suppressed upon overexpression of mir-3099. |
2019-04-11 |
2023-08-13 |
mouse |
JiaRui Zhang, YuXuan Wang, ZiHui Zheng, XiaoHe Sun, TingTing Chen, Chen Li, XiaoLong Zhang, Jun Gu. Intracellular ion and protein nanoparticle-induced osmotic pressure modify astrocyte swelling and brain edema in response to glutamate stimuli. Redox biology. vol 21. 2019-04-01. PMID:30685709. |
the astrocyte swelling resulted in gfap tension increment, which is associated with the antagonistic effect of inward microfilaments (mfs) and microtubules (mts) forces. |
2019-04-01 |
2023-08-13 |
Not clear |
JiaRui Zhang, YuXuan Wang, ZiHui Zheng, XiaoHe Sun, TingTing Chen, Chen Li, XiaoLong Zhang, Jun Gu. Intracellular ion and protein nanoparticle-induced osmotic pressure modify astrocyte swelling and brain edema in response to glutamate stimuli. Redox biology. vol 21. 2019-04-01. PMID:30685709. |
in glutamate-induced astrocyte swelling, gfap tension rise resulted from outward ion and protein nanoparticle-induced osmotic pressure (pn-op) increases, where pn-op could be elicited by mf and mt depolymerization, protein nanoparticle production, and activation of cofilin and stathmin-1. |
2019-04-01 |
2023-08-13 |
Not clear |
Yun Wang, Liming Xie, Ce Gao, Lingyan Zhai, Ning Zhang, Lin Gu. Astrocytes activation contributes to the antidepressant-like effect of ketamine but not scopolamine. Pharmacology, biochemistry, and behavior. vol 170. 2019-03-22. PMID:29729289. |
in the present study, the expression of fibrillary acidic protein (gfap) was detected to evaluate the activation of astrocyte after single injection of ketamine and scopolamine in respective efficient doses. |
2019-03-22 |
2023-08-13 |
Not clear |
Teresa Macheda, Kelly Roberts, Danielle N Lyons, Emma Higgins, Kyle J Ritter, Ai-Ling Lin, Warren J Alilain, Adam D Bachstette. Chronic Intermittent Hypoxia Induces Robust Astrogliosis in an Alzheimer's Disease-Relevant Mouse Model. Neuroscience. vol 398. 2019-03-18. PMID:30529693. |
profiling of genes associated with different phenotypes of astrocyte activation identified gfap, cxcl10, and ggta1 as significant responses activated in the app/ps1 ki mice exposed to chronic ih. |
2019-03-18 |
2023-08-13 |
mouse |
Hwei-Hsien Chen, Pei-Chi Chang, Shiaw-Pyng Wey, Pei-Mei Chen, Chinpiao Chen, Ming-Huan Cha. Therapeutic effects of honokiol on motor impairment in hemiparkinsonian mice are associated with reversing neurodegeneration and targeting PPARγ regulation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-14. PMID:30223096. |
furthermore, honokiol attenuated oxidative stress and reactive astrocyte induction via decreasing nadph-oxidase and glial fibrillary acidic protein (gfap) expressions in 6-ohda-lesioned striatum. |
2019-03-14 |
2023-08-13 |
mouse |
Susmita Sil, Palsamy Periyasamy, Ming-Lei Guo, Shannon Callen, Shilpa Buc. Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29344928. |
our in vitro findings demonstrated upregulation of gfap indicating astrocyte activation with a concomitant increase in the production of proinflammatory cytokines in morphine-exposed human astrocytes. |
2019-02-26 |
2023-08-13 |
human |
Rajesh Kushwaha, Juhi Mishra, Sachin Tripathi, Waseem Raza, Kapil Mandrah, Somendu Kumar Roy, Sanghamitra Bandyopadhya. Arsenic Attenuates Heparin-Binding EGF-Like Growth Factor/EGFR Signaling That Promotes Matrix Metalloprotease 9-Dependent Astrocyte Damage in the Developing Rat Brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 162. issue 2. 2019-02-25. PMID:29228391. |
this reduced hb-egf/egfr was essentially responsible for arsenic-induced astrocyte damage, obvious from a recombinant-hb-egf-mediated recovery in gfap levels and astrocyte morphology and reduction in astrocyte apoptosis, and the reverse by gefitinib. |
2019-02-25 |
2023-08-13 |
rat |
Rajesh Kushwaha, Juhi Mishra, Sachin Tripathi, Waseem Raza, Kapil Mandrah, Somendu Kumar Roy, Sanghamitra Bandyopadhya. Arsenic Attenuates Heparin-Binding EGF-Like Growth Factor/EGFR Signaling That Promotes Matrix Metalloprotease 9-Dependent Astrocyte Damage in the Developing Rat Brain. Toxicological sciences : an official journal of the Society of Toxicology. vol 162. issue 2. 2019-02-25. PMID:29228391. |
thus, our study indicates that via reduced astrocyte and neuronal hb-egf signaling, arsenic may induce mmp9 levels and gfap loss in astrocytes, which might adversely affect bbb integrity of the developing rat brain. |
2019-02-25 |
2023-08-13 |
rat |
Richard Purcell, Gary Lynch, Christine Gall, Steven Johnson, Zhong Sheng, Michael Rajesh Stephen, James Cook, Robert H Garman, Bernard Jortner, Brad Bolon, Daniel Radin, Arnold Lipp. Brain Vacuolation Resulting From Administration of the Type II Ampakine CX717 Is An Artifact Related to Molecular Structure and Chemical Reaction With Tissue Fixative Agents. Toxicological sciences : an official journal of the Society of Toxicology. vol 162. issue 2. 2019-02-25. PMID:29253237. |
vacuole margins were lined by glial fibrillary acidic protein (gfap), and by transmission electron microscopy were shown to be astrocyte processes. |
2019-02-25 |
2023-08-13 |
rat |
Ningfeng Li, Feifei Wang, Qinglin Zhang, Ming Jin, Ye Lu, Shanshan Chen, Cuiju Guo, Xu Zhan. Rapamycin mediates mTOR signaling in reactive astrocytes and reduces retinal ganglion cell loss. Experimental eye research. vol 176. 2019-02-19. PMID:29928901. |
astrocyte activation was assessed by immunostaining retinal flat mounts or cross sections with antibody against gfap, and we also used western blots to detect the expression of gfap. |
2019-02-19 |
2023-08-13 |
rat |
Vidya S Krishnan, Tea Shavlakadze, Miranda D Grounds, Stuart I Hodgetts, Alan R Harve. Age-related loss of VGLUT1 excitatory, but not VGAT inhibitory, immunoreactive terminals on motor neurons in spinal cords of old sarcopenic male mice. Biogerontology. vol 19. issue 5. 2019-02-12. PMID:30084046. |
glial fibrillary acidic protein (gfap) and ionized calcium binding adaptor molecule 1 (iba1) immunostaining was used to monitor changes in astrocyte and microglial phenotype respectively. |
2019-02-12 |
2023-08-13 |
mouse |
Soon-Tae Lee, Youngbeom Seo, Ji-Yeon Bae, Kon Chu, Jin Wook Kim, Seung Hong Choi, Tae Min Kim, Il Han Kim, Sung-Hye Park, Chul-Kee Par. Loss of Pericytes in Radiation Necrosis after Glioblastoma Treatments. Molecular neurobiology. vol 55. issue 6. 2019-02-11. PMID:28770500. |
the rn and their preradiation gbm tissues were serially processed for western blotting using cell-type-specific antibodies against endothelial (cd31, active rhoa), pericyte [platelet-derived growth factor receptor-beta (pdgfr-β)], alpha-smooth muscle actin (α-sma), astrocyte (gfap), myelin sheath protein (mbp), and microglial markers (iba1). |
2019-02-11 |
2023-08-13 |
Not clear |
John J E Mulvihill, Julia Raykin, Eric J Snider, Lisa A Schildmeyer, Irsham Zaman, Manu O Platt, Daniel J Kelly, C Ross Ethie. Development of a Platform for Studying 3D Astrocyte Mechanobiology: Compression of Astrocytes in Collagen Gels. Annals of biomedical engineering. vol 46. issue 2. 2019-02-07. PMID:29181720. |
compressive loading of astrocyte-seeded collagen gels led to cell alignment perpendicular to the direction of strain, and increased astrocyte activation, as assayed by gfap, vimentin, and s100β levels, as well as mmp activity. |
2019-02-07 |
2023-08-13 |
Not clear |
Miranda Brun, Saket Jain, Elizabeth A Monckton, Roseline Godbou. Nuclear Factor I Represses the Notch Effector HEY1 in Glioblastoma. Neoplasia (New York, N.Y.). vol 20. issue 10. 2019-01-28. PMID:30195713. |
nfis have previously been shown to regulate the expression of astrocyte markers such as glial fibrillary acidic protein (gfap) in both normal brain and gbm cells. |
2019-01-28 |
2023-08-13 |
Not clear |