Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Krohn, I Rozovsky, P Wals, B Teter, C P Anderson, C E Finc. Glial fibrillary acidic protein transcription responses to transforming growth factor-beta1 and interleukin-1beta are mediated by a nuclear factor-1-like site in the near-upstream promoter. Journal of neurochemistry. vol 72. issue 4. 1999-04-13. PMID:10098836. |
elevated expression of glial fibrillary acidic protein (gfap) is associated with astrocyte activation during responses to injury in the cns. |
1999-04-13 |
2023-08-12 |
rat |
E Rocha, M Achaval, P Santos, R Rodnigh. Lithium treatment causes gliosis and modifies the morphology of hippocampal astrocytes in rats. Neuroreport. vol 9. issue 17. 1999-03-24. PMID:9875738. |
recently we showed that treatment of rats with clinically relevant doses of lithium chloride results in a 35% increase in the immunocontent of the astrocyte marker gfap in the hippocampus. |
1999-03-24 |
2023-08-12 |
rat |
A Legrand, G Alons. Pregnenolone reverses the age-dependent accumulation of glial fibrillary acidic protein within astrocytes of specific regions of the rat brain. Brain research. vol 802. issue 1-2. 1998-12-24. PMID:9748538. |
in adult (2-3 month-old) and aged (22-24 month-old) rats, quantitative image analysis was used to estimate, within each region, the number of astrocyte cell bodies immunostained (is) for s100, and the surface occupied by astrocytic cell bodies and processes is for glial fibrillary acidic protein (gfap). |
1998-12-24 |
2023-08-12 |
rat |
P K Panegyre. The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 4-5. 1998-10-30. PMID:9720974. |
the kunitz protease inhibitor containing isoform app 770 kpi+, the major glial cell isoform, has been shown to be stimulated after ka and was related to neuronal loss and astrocyte activation as gauged by gfap mrna. |
1998-10-30 |
2023-08-12 |
rat |
J A Weiner, J H Hecht, J Chu. Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain. The Journal of comparative neurology. vol 398. issue 4. 1998-10-29. PMID:9717712. |
double-label in situ hybridization studies demonstrated that vzg-1-expressing cells co-expressed mrna encoding proteolipid protein (plp), a mature oligodendrocyte marker, but not glial fibrillary acidic protein (gfap), an astrocyte marker. |
1998-10-29 |
2023-08-12 |
mouse |
F R Lima, N Gonçalves, F C Gomes, M S de Freitas, V Moura Net. Thyroid hormone action on astroglial cells from distinct brain regions during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 16. issue 1. 1998-10-08. PMID:9664219. |
in this case t3 seems to induce gfap expression which might be occurring as a first step to astrocyte differentiation. |
1998-10-08 |
2023-08-12 |
rat |
A F De Nicola, M Ferrini, S L Gonzalez, M C Gonzalez Deniselle, C A Grillo, G Piroli, F Saravia, E R de Kloe. Regulation of gene expression by corticoid hormones in the brain and spinal cord. The Journal of steroid biochemistry and molecular biology. vol 65. issue 1-6. 1998-08-27. PMID:9699880. |
third, steroid effects on the astrocyte marker glial fibrillary acidic protein (gfap) points to a complex regulatory mechanism. |
1998-08-27 |
2023-08-12 |
mouse |
C I Cha, J M Kim, D H Shin, Y S Kim, J Kim, M E Gurney, K W Le. Reactive astrocytes express nitric oxide synthase in the spinal cord of transgenic mice expressing a human Cu/Zn SOD mutation. Neuroreport. vol 9. issue 7. 1998-08-24. PMID:9631456. |
using antisera directed against gfap, the specific marker for astrocyte, the glial cells were confirmed by immunocytochemistry to be astrocytes. |
1998-08-24 |
2023-08-12 |
mouse |
R D Brinton, R Yamazaki, C M Gonzalez, K O'Neill, S S Schreibe. Vasopressin-induction of the immediate early gene, NGFI-A, in cultured hippocampal glial cells. Brain research. Molecular brain research. vol 57. issue 1. 1998-08-17. PMID:9630527. |
results of combined immunocytochemical labeling for the astrocyte specific marker, gfap, and in situ hybridization for ngfi-a demonstrated that v1 agonist-induced ngfi-a expression occurred in gfap positive cells. |
1998-08-17 |
2023-08-12 |
mouse |
T Kommers, L Vinadé, C Pereira, C A Gonçalves, S Wofchuk, R Rodnigh. Regulation of the phosphorylation of glial fibrillary acidic protein (GFAP) by glutamate and calcium ions in slices of immature rat spinal cord: comparison with immature hippocampus. Neuroscience letters. vol 248. issue 2. 1998-08-17. PMID:9654363. |
the effect of glutamate and lack of external ca2+ on the phosphorylation of the astrocyte cell marker glial fibrillary acidic protein (gfap) was studied in slices of hippocampus and thoracic spinal cord from immature (p12-16) rats. |
1998-08-17 |
2023-08-12 |
rat |
V W Wu, J P Schwart. Cell culture models for reactive gliosis: new perspectives. Journal of neuroscience research. vol 51. issue 6. 1998-06-22. PMID:9545082. |
the hallmark is the increased expression of glial fibrillary acidic protein (gfap), yet studies in gfap knockout mice suggest that gfap may not be required for an astrocyte to become hypertrophic. |
1998-06-22 |
2023-08-12 |
mouse |
E A McKie, D I Graham, S M Brow. Selective astrocytic transgene expression in vitro and in vivo from the GFAP promoter in a HSV RL1 null mutant vector--potential glioblastoma targeting. Gene therapy. vol 5. issue 4. 1998-06-22. PMID:9614567. |
as many intracerebral tumours are glial and predominantly astrocytic in origin, we have evaluated the ability of 1716 to deliver a reporter gene specifically to astrocytes in vivo and in vitro using a 2.2 kb fragment which controls expression of the glial fibrillary acidic protein (gfap), an astrocyte specific protein. |
1998-06-22 |
2023-08-12 |
human |
K Kacem, P Lacombe, J Seylaz, G Bonvent. Structural organization of the perivascular astrocyte endfeet and their relationship with the endothelial glucose transporter: a confocal microscopy study. Glia. vol 23. issue 1. 1998-06-08. PMID:9562180. |
to examine the three-dimensional structure of the astrocyte endfeet and their relationships with the endothelial cells, coronal rat brain sections immunolabeled for the two astroglial markers [glial fibrillary acidic protein (gfap)/s-100beta] and the endothelial glucose transporter (glut1) were analyzed under the confocal microscope. |
1998-06-08 |
2023-08-12 |
rat |
K Kacem, P Lacombe, J Seylaz, G Bonvent. Structural organization of the perivascular astrocyte endfeet and their relationship with the endothelial glucose transporter: a confocal microscopy study. Glia. vol 23. issue 1. 1998-06-08. PMID:9562180. |
double immunostaining of gfap and glut1 showed that the endothelial cells were the main targets of these repeated geometrical units formed by the astrocyte endfeet. |
1998-06-08 |
2023-08-12 |
rat |
N Chauvet, M Prieto, G Alons. Tanycytes present in the adult rat mediobasal hypothalamus support the regeneration of monoaminergic axons. Experimental neurology. vol 151. issue 1. 1998-06-04. PMID:9582250. |
in dorsal lesions, catecholaminergic and serotonergic transected fibers were found to abut onto the scar formed along the surgical cut and composed of closely inderdigitating astrocyte processes strongly immunoreactive for both glial fibrillary acidic protein (gfap) and vimentin (vim). |
1998-06-04 |
2023-08-12 |
rat |
S B Deshpande, H Nishin. In vitro protection of 3-nitropropionic acid-induced toxicity of astrocytes by basic fibroblast growth factor and thrombin. Brain research. vol 783. issue 1. 1998-04-30. PMID:9479039. |
3-npa produced concentration- and time-dependent astrocyte loss as indicated by decrease in the number of glial fibrillary acidic protein (gfap) positive cells and increase in lactate dehydrogenase (ldh) level of the culture medium. |
1998-04-30 |
2023-08-12 |
Not clear |
M Pekny, C Eliasson, C L Chien, L G Kindblom, R Liem, A Hamberger, C Betsholt. GFAP-deficient astrocytes are capable of stellation in vitro when cocultured with neurons and exhibit a reduced amount of intermediate filaments and an increased cell saturation density. Experimental cell research. vol 239. issue 2. 1998-04-16. PMID:9521851. |
using primary astrocyte-enriched cultures from gfap-negative mice, we now report on the effect of gfap absence on (i) the synthesis of other intermediate filament proteins in astrocytes, (ii) intermediate filament formation, (iii) astrocyte process formation (stellation) in response to neurons in mixed cerebellar astrocyte/neuron cultures, and (iv) saturation cell density in vitro. |
1998-04-16 |
2023-08-12 |
mouse |
J A Thomson, V S Marshall, J Q Trojanowsk. Neural differentiation of rhesus embryonic stem cells. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 106. issue 1. 1998-04-14. PMID:9524573. |
younger tumours contained no or few astrocytes indicated by the absence of gfap staining, but as these tumours developed, there was an increase in astrocyte differentiation. |
1998-04-14 |
2023-08-12 |
mouse |
S A Koblar, A M Turnley, B J Classon, K L Reid, C B Ware, S S Cheema, M Murphy, P F Bartlet. Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 6. 1998-04-10. PMID:9501236. |
these findings strongly implicate the lif family of cytokines in the regulation of astrocyte differentiation and indeed the lif-deficient animals show a significant reduction in the number of gfap cells in the hippocampus. |
1998-04-10 |
2023-08-12 |
mouse |
J F Reilly, P A Maher, V G Kumar. Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2. Glia. vol 22. issue 2. 1998-04-09. PMID:9537840. |
regulation of astrocyte gfap expression by tgf-beta1 and fgf-2. |
1998-04-09 |
2023-08-12 |
Not clear |