| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Reilly, P A Maher, V G Kumar. Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2. Glia. vol 22. issue 2. 1998-04-09. PMID:9537840. |
a key indicator of astrocyte activation is the increased accumulation of intermediate filaments composed of glial fibrillary acidic protein (gfap). |
1998-04-09 |
2023-08-12 |
Not clear |
| J F Reilly, P A Maher, V G Kumar. Regulation of astrocyte GFAP expression by TGF-beta1 and FGF-2. Glia. vol 22. issue 2. 1998-04-09. PMID:9537840. |
our results demonstrate that tgf-beta1 and fgf-2 cause differential effects on the astrocyte cytoskeleton and morphology, suggesting an uncoupling of process outgrowth from gfap synthesis. |
1998-04-09 |
2023-08-12 |
Not clear |
| R B Leal, C A Gonçalves, R Rodnigh. Calcium-dependent phosphorylation of glial fibrillary acidic protein (GFAP) in the rat hippocampus: a comparison of the kinase/phosphatase balance in immature and mature slices using tryptic phosphopeptide mapping. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466702. |
in previous work we showed that phosphorylation of the astrocyte marker glial fibrillary acidic protein (gfap) in hippocampal slices from adult rats is dependent on external ca2+, whereas in slices from immature rats aged 12-16 days postnatal 32p incorporation into gfap is inhibited by external ca2+. |
1998-03-20 |
2023-08-12 |
rat |
| L Vinadé, C A Gonçalves, S Wofchuk, C Gottfried, R Rodnigh. Evidence for a role for calcium ions in the dephosphorylation of glial fibrillary acidic protein (GFAP) in immature hippocampal slices and in astrocyte cultures from the rat. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466703. |
evidence for a role for calcium ions in the dephosphorylation of glial fibrillary acidic protein (gfap) in immature hippocampal slices and in astrocyte cultures from the rat. |
1998-03-20 |
2023-08-12 |
rat |
| L Vinadé, C A Gonçalves, S Wofchuk, C Gottfried, R Rodnigh. Evidence for a role for calcium ions in the dephosphorylation of glial fibrillary acidic protein (GFAP) in immature hippocampal slices and in astrocyte cultures from the rat. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466703. |
evidence was sought for a role for ca2+ in the dephosphorylation of the astrocyte marker glial fibrillary acidic protein (gfap) in immature hippocampal slices. |
1998-03-20 |
2023-08-12 |
rat |
| L Vinadé, C A Gonçalves, S Wofchuk, C Gottfried, R Rodnigh. Evidence for a role for calcium ions in the dephosphorylation of glial fibrillary acidic protein (GFAP) in immature hippocampal slices and in astrocyte cultures from the rat. Brain research. Developmental brain research. vol 104. issue 1-2. 1998-03-20. PMID:9466703. |
the direct or indirect association of calcineurin with gfap was suggested by observations showing that fk506, a specific inhibitor of calcineurin, increased the phosphorylation state of gfap in immature slices and of gfap and vimentin in astrocyte cultures. |
1998-03-20 |
2023-08-12 |
rat |
| A Messing, M W Head, K Galles, E J Galbreath, J E Goldman, M Brenne. Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. The American journal of pathology. vol 152. issue 2. 1998-03-06. PMID:9466565. |
fatal encephalopathy with astrocyte inclusions in gfap transgenic mice. |
1998-03-06 |
2023-08-12 |
mouse |
| A Messing, M W Head, K Galles, E J Galbreath, J E Goldman, M Brenne. Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. The American journal of pathology. vol 152. issue 2. 1998-03-06. PMID:9466565. |
to determine whether this increase in gfap expression per se alters astrocyte function, we generated transgenic mice that carry copies of the human gfap gene driven by its own promoter. |
1998-03-06 |
2023-08-12 |
mouse |
| W Liedtke, W Edelmann, F C Chiu, R Kucherlapati, C S Rain. Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion. The American journal of pathology. vol 152. issue 1. 1998-01-30. PMID:9422542. |
insights into the role of the astrocyte intermediate filament protein, glial fibrillary acidic protein (gfap), have only recently emerged with reports on subtle abnormalities in gfap-deficient mice, including the documentation of defective long-term maintenance of central nervous system myelination. |
1998-01-30 |
2023-08-12 |
mouse |
| C Guerri, J Renau-Piquera. Alcohol, astroglia, and brain development. Molecular neurobiology. vol 15. issue 1. 1998-01-15. PMID:9396005. |
however, brief exposure of rats to high levels of ethanol during the neonatal period (the period of astrocyte differentiation) causes a transient gliosis, with an increase in gfap and its mrna levels. |
1998-01-15 |
2023-08-12 |
rat |
| G Moretto, N Brutti, V De Angelis, C Arcuri, V Bocchin. A time-dependent increase in glial fibrillary acidic protein expression and glutamine synthetase activity in long-term subculture of the GL15 glioma cell line. Cellular and molecular neurobiology. vol 17. issue 5. 1998-01-02. PMID:9353592. |
using a poorly differentiated glioma cell line, gl15, we investigated whether, in long-term subculture, this could upregulate the expression of glial fibrillary acidic protein (gfap), as described in some rodent astrocyte cell lines. |
1998-01-02 |
2023-08-12 |
Not clear |
| G Moretto, N Brutti, V De Angelis, C Arcuri, V Bocchin. A time-dependent increase in glial fibrillary acidic protein expression and glutamine synthetase activity in long-term subculture of the GL15 glioma cell line. Cellular and molecular neurobiology. vol 17. issue 5. 1998-01-02. PMID:9353592. |
our results suggest that, in gl15, gfap and gs genes may have common or integrated regulatory mechanisms elicited at the cell confluency which could be relevant for both astrocyte physiology and astrocyte pathology. |
1998-01-02 |
2023-08-12 |
Not clear |
| R C Melcangi, V Magnaghi, I Cavarretta, M A Riva, L Martin. Corticosteroid effects on gene expression of myelin basic protein in oligodendrocytes and of glial fibrillary acidic protein in type 1 astrocytes. Journal of neuroendocrinology. vol 9. issue 10. 1997-12-23. PMID:9355041. |
in conclusion, the present data show that: (1) adrenal steroids possessing gluco- and mineralocorticoid activities may influence the gene expression of the astrocytic marker gfap; (2) the 5 alpha-reduced metabolite of doc, dhdoc is able to influence the gene expression not only of gfap but also that of mbp, which are, respectively, typical markers of the astrocytes and the oligodendrocytes; (3) the metabolic conversion of hormonal steroids into their 5 alpha-reduced metabolites, which also occurs in the glia, could be implicated in the biochemical control of oligodendrocyte and astrocyte functions. |
1997-12-23 |
2023-08-12 |
rat |
| R C Melcangi, M Galbiati, E Messi, V Magnaghi, I Cavarretta, M A Riva, M Zanis. Astrocyte-neuron interactions in vitro: role of growth factors and steroids on LHRH dynamics. Brain research bulletin. vol 44. issue 4. 1997-12-23. PMID:9370212. |
moreover, type 1 astrocytes are sensitive to steroid hormones, and in particular to the 5alpha-reduced metabolites of progesterone; this has been shown by analyzing the effects exerted by different steroids on the gene expression of the typical astrocyte marker gfap. |
1997-12-23 |
2023-08-12 |
mouse |
| D A Hinkle, S A Baldwin, S W Scheff, P M Wis. GFAP and S100beta expression in the cortex and hippocampus in response to mild cortical contusion. Journal of neurotrauma. vol 14. issue 10. 1997-12-23. PMID:9383091. |
we further analyzed the effect of contusion on gfap and s100beta immunoreactive astrocyte density at 96 h postlesion or postsham by double-label immunocytochemistry. |
1997-12-23 |
2023-08-12 |
rat |
| F Amenta, M Sabbatini, G Coppi, A Maggioni, V Olgiati, I Panock. Effect of treatment with the neuroactive peptide posatirelin on microanatomical changes of frontal cortex and hippocampus caused by lesions of the locus coeruleus. Drugs under experimental and clinical research. vol 23. issue 2. 1997-11-18. PMID:9309383. |
the influence of monolateral and bilateral lesions of the locus coeruleus (lc) on the number of nerve cell and glial fibrillary acidic protein (gfap)-immunoreactive astrocyte profiles, on silver-gold impregnated fibres and on tyrosine hydroxylase (th) immunoreactivity was assessed in the rat frontal cortex and hippocampus. |
1997-11-18 |
2023-08-12 |
rat |
| R Rodnight, C A Gonçalves, S T Wofchuk, R Lea. Control of the phosphorylation of the astrocyte marker glial fibrillary acidic protein (GFAP) in the immature rat hippocampus by glutamate and calcium ions: possible key factor in astrocytic plasticity. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 30. issue 3. 1997-11-13. PMID:9246230. |
control of the phosphorylation of the astrocyte marker glial fibrillary acidic protein (gfap) in the immature rat hippocampus by glutamate and calcium ions: possible key factor in astrocytic plasticity. |
1997-11-13 |
2023-08-12 |
rat |
| D Dziewulsk. Age-dependent changes in astroglial reactivity in human ischemic stroke. Immunohistochemical study. Folia neuropathologica. vol 35. issue 2. 1997-11-10. PMID:9377083. |
astrocyte reactivity was evaluated using immunohistochemical methods with antibodies against: protein s-100, gfap, vimentin and recombinant parts of the ki-67 molecule (mib-1 antibody) during 32 days after the disease onset. |
1997-11-10 |
2023-08-12 |
human |
| G M Pasinetti, G Tocco, S Sakhi, W D Musleh, M G DeSimoni, P Mascarucci, S Schreiber, M Baudry, C E Finc. Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions. Neurobiology of disease. vol 3. issue 3. 1997-10-23. PMID:8980020. |
in response to the excitotoxin kainic acid (ka), c5- mice had more hippocampal pyramidal neuron death and greater induction of astrocyte mrnas (gfap, apoe, apoj). |
1997-10-23 |
2023-08-12 |
mouse |
| J Jordan, M Böttner, H J Schluesener, K Unsicker, K Krieglstei. Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells. The European journal of neuroscience. vol 9. issue 8. 1997-10-16. PMID:9283824. |
bmps 2, 4, 6, 7, 9 and 12 also promoted dna synthesis and astroglial cell differentiation, visualized by 5-bromodeoxyuridine (brdu) incorporation and glial fibrillary acidic protein (gfap) immunocytochemistry respectively. |
1997-10-16 |
2023-08-12 |
rat |