| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michelle Day, David Wokosin, Joshua L Plotkin, Xinyoung Tian, D James Surmeie. Differential excitability and modulation of striatal medium spiny neuron dendrites. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 45. 2008-12-31. PMID:18987196. |
the loss of striatal dopamine (da) in parkinson's disease (pd) models triggers a cell-type-specific reduction in the density of dendritic spines in d(2) receptor-expressing striatopallidal medium spiny neurons (d(2) msns). |
2008-12-31 |
2023-08-12 |
mouse |
| Daniela V F Rosa, Renan P Souza, Bruno R Souza, Melissa M Guimarães, Daniel S Carneiro, Samira S Valvassori, Marcus V Gomez, João Quevedo, Marco A Romano-Silv. DARPP-32 expression in rat brain after an inhibitory avoidance task. Neurochemical research. vol 33. issue 11. 2008-12-12. PMID:18415674. |
darpp-32 (dopamine and camp regulated phosphoprotein of mr 32 kda) is a cytosolic protein that is selectively enriched in medium spiny neurons in the neostriatum. |
2008-12-12 |
2023-08-12 |
mouse |
| Marat V Avshalumov, Jyoti C Patel, Margaret E Ric. AMPA receptor-dependent H2O2 generation in striatal medium spiny neurons but not dopamine axons: one source of a retrograde signal that can inhibit dopamine release. Journal of neurophysiology. vol 100. issue 3. 2008-12-12. PMID:18632893. |
ampa receptor-dependent h2o2 generation in striatal medium spiny neurons but not dopamine axons: one source of a retrograde signal that can inhibit dopamine release. |
2008-12-12 |
2023-08-12 |
Not clear |
| Marat V Avshalumov, Jyoti C Patel, Margaret E Ric. AMPA receptor-dependent H2O2 generation in striatal medium spiny neurons but not dopamine axons: one source of a retrograde signal that can inhibit dopamine release. Journal of neurophysiology. vol 100. issue 3. 2008-12-12. PMID:18632893. |
here, we used whole cell recording, fluorescence imaging of h2o2, and voltammetric detection of evoked dopamine release in guinea pig striatal slices to examine contributions from medium spiny neurons (msns), the principal neurons of striatum, and dopamine axons to ampar-dependent h2o2 generation. |
2008-12-12 |
2023-08-12 |
Not clear |
| Marat V Avshalumov, Jyoti C Patel, Margaret E Ric. AMPA receptor-dependent H2O2 generation in striatal medium spiny neurons but not dopamine axons: one source of a retrograde signal that can inhibit dopamine release. Journal of neurophysiology. vol 100. issue 3. 2008-12-12. PMID:18632893. |
together, these findings suggest that glutamatergic regulation of dopamine release via ampars is mediated through retrograde signaling by diffusible h2o2 generated in striatal cells, including medium spiny neurons, rather than in dopamine axons. |
2008-12-12 |
2023-08-12 |
Not clear |
| Anders Borgkvist, Emmanuel Valjent, Emanuela Santini, Denis Hervé, Jean-Antoine Girault, Gilberto Fison. Delayed, context- and dopamine D1 receptor-dependent activation of ERK in morphine-sensitized mice. Neuropharmacology. vol 55. issue 2. 2008-11-25. PMID:18614186. |
using transgenic mice with enhanced green fluorescent protein (egfp) expression under the control of the dopamine d1 receptor (d1r) (drd1a-egfp) or d2 receptor promoter (drd2-egfp) we show that context-dependent erk phosphorylation is restricted to d1r-expressing medium spiny neurons. |
2008-11-25 |
2023-08-12 |
mouse |
| Li Liang, Mahlon R DeLong, Stella M Pap. Inversion of dopamine responses in striatal medium spiny neurons and involuntary movements. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 30. 2008-09-02. PMID:18650331. |
inversion of dopamine responses in striatal medium spiny neurons and involuntary movements. |
2008-09-02 |
2023-08-12 |
monkey |
| Li Liang, Mahlon R DeLong, Stella M Pap. Inversion of dopamine responses in striatal medium spiny neurons and involuntary movements. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 30. 2008-09-02. PMID:18650331. |
the basic mechanisms lie in differential dopamine responses of medium spiny neurons (msns) contributing to striatal output pathways. |
2008-09-02 |
2023-08-12 |
monkey |
| Weixing Shen, Marc Flajolet, Paul Greengard, D James Surmeie. Dichotomous dopaminergic control of striatal synaptic plasticity. Science (New York, N.Y.). vol 321. issue 5890. 2008-08-19. PMID:18687967. |
at synapses between cortical pyramidal neurons and principal striatal medium spiny neurons (msns), postsynaptic d1 and d2 dopamine (da) receptors are postulated to be necessary for the induction of long-term potentiation and depression, respectively-forms of plasticity thought to underlie associative learning. |
2008-08-19 |
2023-08-12 |
mouse |
| Emanuela Santini, Emmanuel Valjent, Gilberto Fison. Parkinson's disease: levodopa-induced dyskinesia and signal transduction. The FEBS journal. vol 275. issue 7. 2008-06-03. PMID:18279379. |
accumulating evidence suggests that lid derives from overstimulation of dopamine receptors located on the gabaergic medium spiny neurons (msns) of the dorsal striatum. |
2008-06-03 |
2023-08-12 |
Not clear |
| Francesco Errico, Emanuela Santini, Sara Migliarini, Anders Borgkvist, Diego Centonze, Valentina Nasti, Manolo Carta, Valentina De Chiara, Chiara Prosperetti, Daniela Spano, Denis Herve, Massimo Pasqualetti, Roberto Di Lauro, Gilberto Fisone, Alessandro Usiell. The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons. Molecular and cellular neurosciences. vol 37. issue 2. 2008-04-25. PMID:18035555. |
the gtp-binding protein rhes modulates dopamine signalling in striatal medium spiny neurons. |
2008-04-25 |
2023-08-12 |
mouse |
| Anders Borgkvist, Daniel Marcellino, Kjell Fuxe, Paul Greengard, Gilberto Fison. Regulation of DARPP-32 phosphorylation by Delta9-tetrahydrocannabinol. Neuropharmacology. vol 54. issue 1. 2008-04-18. PMID:17686497. |
these results indicate that, in the striatum, thc promotes pka-dependent phosphorylation of darpp-32 in striatal medium spiny neurons expressing dopamine d1 and adenosine a2a receptors. |
2008-04-18 |
2023-08-12 |
Not clear |
| M D Neely, D E Schmidt, A Y Deutc. Cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17888581. |
cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons. |
2008-01-16 |
2023-08-12 |
rat |
| M D Neely, D E Schmidt, A Y Deutc. Cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons. Neuroscience. vol 149. issue 2. 2008-01-16. PMID:17888581. |
although no overt toxicity to striatal neurons has been reported in parkinson's disease, one of the consequences of striatal dopamine loss is a decrease in the number of dendritic spines on striatal medium spiny neurons (msns). |
2008-01-16 |
2023-08-12 |
rat |
| Anders Borgkvist, Alessandro Usiello, Paul Greengard, Gilberto Fison. Activation of the cAMP/PKA/DARPP-32 signaling pathway is required for morphine psychomotor stimulation but not for morphine reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 9. 2007-11-29. PMID:17251906. |
these results demonstrate that dopamine d1 receptor-mediated activation of the camp/darpp-32 cascade in striatal medium spiny neurons is involved in the psychomotor action, but not in the rewarding properties, of morphine. |
2007-11-29 |
2023-08-12 |
mouse |
| Masami Miura, Sachiko Saino-Saito, Masao Masuda, Kazuto Kobayashi, Toshihiko Aosak. Compartment-specific modulation of GABAergic synaptic transmission by mu-opioid receptor in the mouse striatum with green fluorescent protein-expressing dopamine islands. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 36. 2007-10-02. PMID:17804632. |
we made patch-clamp recordings from medium spiny neurons in identified mor-immunoreactive "dopamine islands" as striosomes in a slice preparation taken from transgenic mice expressing green fluorescent protein in tyrosine hydroxylase mrna-containing neurons. |
2007-10-02 |
2023-08-12 |
mouse |
| Jacqueline F McGint. Co-localization of GABA with other neuroactive substances in the basal ganglia. Progress in brain research. vol 160. 2007-09-28. PMID:17499120. |
the dorsal striatum (caudate putamen) contains two types of gabaergic medium spiny neurons (msns) that are distinguished by the expression of either the opioid peptide, enkephalin, or the opioid peptide, dynorphin, as well as the tachykinin substance p. pharmacological studies suggest that these peptides modulate local neurotransmission in the striatum in response to direct and indirect dopamine agonists. |
2007-09-28 |
2023-08-12 |
Not clear |
| R E Colebrooke, P M Chan, P J Lynch, K Mooslehner, P C Emso. Differential gene expression in the striatum of mice with very low expression of the vesicular monoamine transporter type 2 gene. Brain research. vol 1152. 2007-08-27. PMID:17433807. |
dopamine released from mid-brain dopamine neurons acts on post-synaptic type 1 (d1) and 2 (d2) receptors located on striatal medium spiny neurons to initiate a signalling cascade that leads to altered transcription factor activity, gene expression and neuronal activity. |
2007-08-27 |
2023-08-12 |
mouse |
| A M Hein, A Sridharan, K W Nordeen, E J Nordee. Characterization of CaMKII-expressing neurons within a striatal region implicated in avian vocal learning. Brain research. vol 1155. 2007-08-13. PMID:17493595. |
ltp) underlying learning and memory, and electrophysiological studies have demonstrated nmda and dopamine (da) receptor-dependent ltp among area x medium spiny neurons [ding, l., perkel, d.j., 2002. |
2007-08-13 |
2023-08-12 |
Not clear |
| A M Hein, A Sridharan, K W Nordeen, E J Nordee. Characterization of CaMKII-expressing neurons within a striatal region implicated in avian vocal learning. Brain research. vol 1155. 2007-08-13. PMID:17493595. |
virtually all (approximately 98%) area x cells expressing camkii also expressed darpp-32 (dopamine- and adenosine 3'5'-monophosphate-regulated phosphoprotein), a dopamine signaling protein enriched in medium spiny striatal neurons. |
2007-08-13 |
2023-08-12 |
Not clear |