| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Csaba Vastagh, Fabrizio Gardoni, Vincenza Bagetta, Jennifer Stanic, Elisa Zianni, Carmen Giampà, Barbara Picconi, Paolo Calabresi, Monica Di Luc. N-methyl-D-aspartate (NMDA) receptor composition modulates dendritic spine morphology in striatal medium spiny neurons. The Journal of biological chemistry. vol 287. issue 22. 2012-08-15. PMID:22493505. |
dendritic spines of medium spiny neurons represent an essential site of information processing between nmda and dopamine receptors in striatum. |
2012-08-15 |
2023-08-12 |
Not clear |
| Serene Keilani, Samira Chandwani, Georgia Dolios, Alexey Bogush, Heike Beck, Antonis K Hatzopoulos, Gadiparthi N Rao, Elizabeth A Thomas, Rong Wang, Michelle E Ehrlic. Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 20. 2012-07-27. PMID:22593050. |
darpp-32 (dopamine and adenosine 3', 5'-cyclic monophosphate camp-regulated phosphoprotein, 32 kda) is a striatal-enriched protein that mediates signaling by dopamine and other first messengers in the medium spiny neurons. |
2012-07-27 |
2023-08-12 |
mouse |
| Rodrigo F Oliveira, Myungsook Kim, Kim T Blackwel. Subcellular location of PKA controls striatal plasticity: stochastic simulations in spiny dendrites. PLoS computational biology. vol 8. issue 2. 2012-06-04. PMID:22346744. |
we have developed a large scale stochastic reaction-diffusion model of signaling pathways in a medium spiny projection neuron dendrite with spines, based on published biochemical measurements, to investigate this question and to evaluate whether dopamine signaling exhibits spatial specificity post-synaptically. |
2012-06-04 |
2023-08-12 |
Not clear |
| Monica S Guzman, Xavier De Jaeger, Sanda Raulic, Ivana A Souza, Alex X Li, Susanne Schmid, Ravi S Menon, Raul R Gainetdinov, Marc G Caron, Robert Bartha, Vania F Prado, Marco A M Prad. Elimination of the vesicular acetylcholine transporter in the striatum reveals regulation of behaviour by cholinergic-glutamatergic co-transmission. PLoS biology. vol 9. issue 11. 2012-05-17. PMID:22087075. |
however, dopaminergic sensitivity of medium spiny neurons (msn) and the behavioural outputs in response to direct dopaminergic agonists were enhanced, likely due to increased expression/function of dopamine receptors in the striatum. |
2012-05-17 |
2023-08-12 |
mouse |
| Maxime Cazorla, Mariya Shegda, Bhavani Ramesh, Neil L Harrison, Christoph Kellendon. Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 7. 2012-04-23. PMID:22396414. |
medium spiny neurons of the striatum show a high degree of structural plasticity that is modulated by dopamine through unknown signaling mechanisms. |
2012-04-23 |
2023-08-12 |
mouse |
| Maxime Cazorla, Mariya Shegda, Bhavani Ramesh, Neil L Harrison, Christoph Kellendon. Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 7. 2012-04-23. PMID:22396414. |
here, we demonstrate that overexpression of dopamine d2 receptors in medium spiny neurons increases their membrane excitability and decreases the complexity and length of their dendritic arbors. |
2012-04-23 |
2023-08-12 |
mouse |
| M L Berlanga, D L Price, B S Phung, R Giuly, M Terada, N Yamada, M Cyr, M G Caron, A Laakso, M E Martone, M H Ellisma. Multiscale imaging characterization of dopamine transporter knockout mice reveals regional alterations in spine density of medium spiny neurons. Brain research. vol 1390. 2012-03-07. PMID:21439946. |
multiscale imaging characterization of dopamine transporter knockout mice reveals regional alterations in spine density of medium spiny neurons. |
2012-03-07 |
2023-08-12 |
mouse |
| Masao Masuda, Masami Miura, Ritsuko Inoue, Michiko Imanishi, Sachiko Saino-Saito, Masahiko Takada, Kazuto Kobayashi, Toshihiko Aosak. Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum. The European journal of neuroscience. vol 34. issue 9. 2012-02-17. PMID:22004548. |
the striatum harbors a small number of tyrosine hydroxylase (th) mrna-containing gabaergic neurons that express th immunoreactivity after dopamine depletion, some of which reportedly resembled striatal medium spiny projection neurons (msns). |
2012-02-17 |
2023-08-12 |
mouse |
| Z Qi, S Kikuchi, F Tretter, E O Voi. Effects of dopamine and glutamate on synaptic plasticity: a computational modeling approach for drug abuse as comorbidity in mood disorders. Pharmacopsychiatry. vol 44 Suppl 1. 2011-12-19. PMID:21544747. |
model simulations show that gabaergic medium spiny neurons tend to respond to dopamine stimuli with synaptic potentiation and to glutamate signals with synaptic depression. |
2011-12-19 |
2023-08-12 |
Not clear |
| Tomoyuki Mitsumori, Tomoyuki Furuyashiki, Toshihiko Momiyama, Akinori Nishi, Takahide Shuto, Takashi Hayakawa, Fumitaka Ushikubi, Shiho Kitaoka, Tomohiro Aoki, Haruhisa Inoue, Toshiyuki Matsuoka, Shuh Narumiy. Thromboxane receptor activation enhances striatal dopamine release, leading to suppression of GABAergic transmission and enhanced sugar intake. The European journal of neuroscience. vol 34. issue 4. 2011-12-07. PMID:21749493. |
as a functional consequence of tp-mediated dopamine increase, a tp agonist suppressed gabaergic inhibitory postsynaptic currents in medium spiny neurons through a d2-like receptor-dependent mechanism. |
2011-12-07 |
2023-08-12 |
Not clear |
| Jacqueline F McGinty, Alexandra J Bache, Nortorious T Coleman, Wei-Lun Su. The Role of BDNF/TrkB Signaling in Acute Amphetamine-Induced Locomotor Activity and Opioid Peptide Gene Expression in the Rat Dorsal Striatum. Frontiers in systems neuroscience. vol 5. 2011-11-10. PMID:21811445. |
further, there may be an interaction between the intracellular signaling cascades activated by dopamine, glutamate, and trkb receptors in medium spiny striatal neurons. |
2011-11-10 |
2023-08-12 |
rat |
| Megan J Janssen, Robert P Yasuda, Stefano Vicin. GABA(A) Receptor β3 Subunit Expression Regulates Tonic Current in Developing Striatopallidal Medium Spiny Neurons. Frontiers in cellular neuroscience. vol 5. 2011-11-10. PMID:21847370. |
the striatum is a key structure for movement control, but the mechanisms that dictate the output of distinct subpopulations of medium spiny projection neurons (msns), striatonigral projecting and dopamine d1 receptor- (d1+) or striatopallidal projecting and dopamine d2 receptor- (d2+) expressing neurons, remains poorly understood. |
2011-11-10 |
2023-08-12 |
mouse |
| b' Denis Herv\\xc3\\xa. Identification of a specific assembly of the g protein golf as a critical and regulated module of dopamine and adenosine-activated cAMP pathways in the striatum. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21886607.' |
in the principal neurons of striatum (medium spiny neurons, msns), camp pathway is primarily activated through the stimulation of dopamine d1 and adenosine a(2a) receptors, these receptors being mainly expressed in striatonigral and striatopallidal msns, respectively. |
2011-11-10 |
2023-08-12 |
Not clear |
| Sven Ivar Walaas, Hugh Caroll Hemmings, Paul Greengard, Angus Clark Nair. Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases. Frontiers in neuroanatomy. vol 5. 2011-11-10. PMID:21904525. |
our studies over the last 30 years have focused on the molecular actions of dopamine acting on medium spiny neurons, the predominant neurons of the neostriatum. |
2011-11-10 |
2023-08-12 |
Not clear |
| Michael Feyder, Alessandra Bonito-Oliva, Gilberto Fison. L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:22028687. |
l-dopa-induced dyskinesia and abnormal signaling in striatal medium spiny neurons: focus on dopamine d1 receptor-mediated transmission. |
2011-11-10 |
2023-08-12 |
mouse |
| Michael Feyder, Alessandra Bonito-Oliva, Gilberto Fison. L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission. Frontiers in behavioral neuroscience. vol 5. 2011-11-10. PMID:22028687. |
accumulating evidence indicates that l-dopa-induced dyskinesia (lid) is primarily caused by the development of sensitized dopamine d1 receptor (d1r) transmission in the medium spiny neurons (msns) of the striatum. |
2011-11-10 |
2023-08-12 |
mouse |
| Jones G Parker, Lisa R Beutler, Richard D Palmite. The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 31. 2011-10-11. PMID:21813695. |
nmdar signaling in dopamine neurons was not required for pavlovian conditioning; however, nmdars in d(1) dopamine receptor (d(1)r)-expressing medium spiny neurons (msns), which receive input from dopamine neurons, were critical for this type of learning. |
2011-10-11 |
2023-08-12 |
mouse |
| L Agnoli, M Carl. Synergistic interaction of dopamine D₁ and glutamate N-methyl-D-aspartate receptors in the rat dorsal striatum controls attention. Neuroscience. vol 185. 2011-09-19. PMID:21536111. |
the balance between corticostriatal glutamate inputs and mesostriatal dopamine afferents converging onto the same postsynaptic spines of striatal medium spiny neurons in the dorsal striatum is believed to be crucial for regulating executive functions including attention.in the present study we examined the role of dopamine d(1) and glutamate n-methyl-d-aspartate (nmda) receptors within the medial territory of the dorsal striatum (dm-str) of the rat during performance of a selective attention task such as the 5-choice serial reaction time (5-csrt) task, which incorporates a variety of measures including accuracy of visual discrimination (an index of attentional functioning), omissions, premature and perseverative responses (indices of inhibitory response control) and correct response latency (decision time). |
2011-09-19 |
2023-08-12 |
rat |
| Marina E Wol. Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine. Neurotoxicity research. vol 18. issue 3-4. 2011-09-15. PMID:20361291. |
elevation of dopamine levels (as would occur following cocaine exposure) facilitates activity-dependent strengthening of excitatory synapses onto medium spiny neurons, the main cell type and projection neuron of the nac. |
2011-09-15 |
2023-08-12 |
rat |
| Juhyun Kim, Bong-Hyun Park, Joo Han Lee, Sang Ki Park, Joung-Hun Ki. Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine. Biological psychiatry. vol 69. issue 11. 2011-09-12. PMID:21377654. |
a major proportion of nac neurons consists of medium spiny neurons (msns), commonly divided into two major subsets on the basis of their expression of d1 dopamine receptors (d1r-msns) or d2 dopamine receptors (d2r-msns). |
2011-09-12 |
2023-08-12 |
Not clear |