| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bao-Dong He, Chang-Mei Liu, Zhao-Qian Ten. A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus. Biology. vol 11. issue 9. 2022-09-23. PMID:36138848. |
mice with a hippocampal blade stab injury (hbsi) displayed the activation of microglia and astrocytes, inflammation, neuronal apoptosis, and deficits in spatial learning and memory. |
2022-09-23 |
2023-08-14 |
mouse |
| Tianze Yu, Yi Chen, Jiani Lu, Luyun Gong, Yuechen Mao, Xinya Liu, Yiying Zhou, Lei Guo, Xiang Wu, Junfang Zhang, Chuang Wang, Haowei Shen, Wenhua Zhou, Disen Mei, Wei Cu. Chronic multiple mild stress induces sustained adverse psychological states in rats. Neuroreport. vol 33. issue 15. 2022-09-20. PMID:36126265. |
furthermore, these antidepressants prevented the cmms-induced inhibition of brain-derived neurotrophic factor/camp-response element binding protein pathway, reduction of synaptic protein expression, and the activation of microglia and astrocytes in the hippocampus and the prefrontal cortex of rats. |
2022-09-20 |
2023-08-14 |
human |
| Barbara B Shih, Sarah M Brown, Jack Barrington, Lucas Lefevre, Neil A Mabbott, Josef Priller, Gerard Thompson, Alistair B Lawrence, Barry W McCol. Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia. Glia. 2022-09-19. PMID:36120803. |
we isolated pig hippocampal tissue and microglia from frontal cortex, hippocampus, and cerebellum, as well as alveolar macrophages from the lungs and conducted rna-sequencing (rnaseq). |
2022-09-19 |
2023-08-14 |
mouse |
| Barbara B Shih, Sarah M Brown, Jack Barrington, Lucas Lefevre, Neil A Mabbott, Josef Priller, Gerard Thompson, Alistair B Lawrence, Barry W McCol. Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia. Glia. 2022-09-19. PMID:36120803. |
by comparing the transcriptomic profiles between microglia, macrophages, and hippocampal tissue, we derived a set of 239 highly enriched genes defining the porcine core microglial signature. |
2022-09-19 |
2023-08-14 |
mouse |
| Yuhua Ji, Zixin Chen, Ziqi Cen, Yuting Ye, Shuyuan Li, Xiaoshuang Lu, Qian Shao, Donghao Wang, Juling Ji, Qiuhong J. A comprehensive mouse brain acetylome-the cellular-specific distribution of acetylated brain proteins. Frontiers in cellular neuroscience. vol 16. 2022-09-16. PMID:36111245. |
further immunofluorescence staining illustrated that acetylated proteins were mainly distributed in the nuclei of cortex neurons and axons of hippocampal neurons, sparsely distributed in the nuclei of microglia and astrocytes, and the lack of distribution in both cytoplasm and nuclei of cerebrovascular endothelial cells. |
2022-09-16 |
2023-08-14 |
mouse |
| Chenlu Xu, Jia Zhang, Qinfeng Zhou, Juling Wang, Chenyang Liu, Yu Tian, Danni Huang, Huaizhuang Ye, Yongtang Ji. Exposure to a real traffic environment impairs brain cognition in aged mice. Environmental research. 2022-09-16. PMID:36113572. |
trap exposure increased the number of activated microglia in the hippocampal dg, ca1, ca3 regions and dorsolateral prefrontal cortex (dpfc). |
2022-09-16 |
2023-08-14 |
mouse |
| Weiping Xiao, Jiaying Li, Xinjie Gao, Heng Yang, Jiabin Su, Ruiyuan Weng, Yanqin Gao, Wei Ni, Yuxiang G. Involvement of the gut-brain axis in vascular depression via tryptophan metabolism: A benefit of short chain fatty acids. Experimental neurology. 2022-09-13. PMID:36100045. |
in addition to inhibiting the upregulation of inflammatory cytokines, scfa supplementation ameliorated the activated oxidative stress and reduced the number of microglia and the expression of its proinflammatory markers in the hippocampus post bccao. |
2022-09-13 |
2023-08-14 |
rat |
| Xiaolin Zhong, Zuyao Chen, Yajuan Wang, Mingli Mao, Yingcheng Deng, Mengmeng Shi, Yang Xu, Ling Chen, Wenyu Ca. JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE. Brain research bulletin. 2022-09-13. PMID:36100190. |
interestingly, we also found that jq1 selectively suppressed the activation of hippocampal microglia in sae mice. |
2022-09-13 |
2023-08-14 |
mouse |
| Lubriel Sambolín-Escobales, Adariana Feliciano-Quiñones, Lizmarie Tirado-Castro, Cristina Suárez, Dariangelly Pacheco-Cruz, Nashaly Irizarry-Méndez, Wilfred Fonseca-Ferrer, Anixa Hernández-López, María Colón-Romero, James T Porte. Infusion of C20:0 ceramide into ventral hippocampus triggers anhedonia-like behavior in female and male rats. Frontiers in behavioral neuroscience. vol 16. 2022-09-12. PMID:36090653. |
in this study, we determined whether localized infusion of c20:0 ceramides into the ventral hippocampus (vh) of rats is sufficient to activate microglia and induce depressive-like behaviors. |
2022-09-12 |
2023-08-14 |
rat |
| Aarti Nagayach, Rakesh Bhaskar, Ishan Patr. Microglia activation and inflammation in hippocampus attenuates memory and mood functions during experimentally induced diabetes in rat. Journal of chemical neuroanatomy. 2022-09-11. PMID:36089179. |
microglia activation and inflammation in hippocampus attenuates memory and mood functions during experimentally induced diabetes in rat. |
2022-09-11 |
2023-08-14 |
rat |
| Aarti Nagayach, Rakesh Bhaskar, Ishan Patr. Microglia activation and inflammation in hippocampus attenuates memory and mood functions during experimentally induced diabetes in rat. Journal of chemical neuroanatomy. 2022-09-11. PMID:36089179. |
we examined the possible involvement of microglia activation, macrophage response, oxidative stress and inflammatory stature in both ventral and dorsal hippocampus of rats rendered diabetic by a single injection of streptozotocin (stz; 45mg/ kg body weight; intraperitoneal). |
2022-09-11 |
2023-08-14 |
rat |
| Alexander Beletskiy, Ekaterina Positselskaya, Aliya Kh Vinarskaya, Yulia S Spivak, Yulia V Dobryakova, Iliya Tyulenev, Vladimir A Markevich, Alexey P Bolshako. Detailed Analysis of Dorsal-Ventral Gradients of Gene Expression in the Hippocampus of Adult Rats. International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077346. |
furthermore, analysis of differential expressions of genes specific for astrocytes, microglia, oligodendrocytes, and vascular cells suggests that non-neuronal cells may also differ in the characteristics between hippocampal parts. |
2022-09-09 |
2023-08-14 |
rat |
| Chong Song, Wei Wei, Tong Wang, Min Zhou, Yunshi Li, Bing Xiao, Dongyi Huang, Junwei Gu, Linyong Shi, Junjie Peng, Dianshi Ji. Microglial infiltration mediates cognitive dysfunction in rat models of hypothalamic obesity Frontiers in cellular neuroscience. vol 16. 2022-09-08. PMID:36072565. |
furthermore, neuronal apoptosis and activated microglia in the downstream of the lesion area (the lha) induced microglial infiltration into the intact hippocampus |
2022-09-08 |
2023-08-14 |
rat |
| Lauren McClure Yauch, Kathleen Ennis-Czerniak, William H Frey Ii, Ivan Tkac, Raghavendra B Ra. Intranasal Insulin Attenuates the Long-term Adverse Effects of Neonatal Hyperglycemia on the Hippocampus in Rats. Developmental neuroscience. 2022-08-30. PMID:36041414. |
compared with the stz group, phosphocreatine and phosphocreatine/creatine ratio were higher, and microglia in the hippocampal subareas fewer in the stz + ins group (p < 0.05 for all). |
2022-08-30 |
2023-08-14 |
rat |
| Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
staining of hippocampal sections of mouse brain tissue showed that, in the ca1, ca2, and dg areas, the number of neurons decreased, the nucleus was pyknotic, the cell body was atrophied, and levels of the microglia marker iba-1 increased. |
2022-08-30 |
2023-08-14 |
mouse |
| Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment. 2022-08-30. PMID:36041608. |
the experimental results demonstrated that the mechanism of the combined-exposure injury to neurons in the hippocampus of mice may be that mwcnts with adsorbed dbp can induce the release of bdnf, accelerate the apoptosis of neurons, and reduce the number of nerve cells, which activates microglia, causing neuroinflammation and nervous system toxicity. |
2022-08-30 |
2023-08-14 |
mouse |
| Leonardo C Souza, Marcos K Andrade, Evellyn M Azevedo, Daniele C Ramos, Ellen L Bail, Maria A B F Vita. Andrographolide Attenuates Short-Term Spatial and Recognition Memory Impairment and Neuroinflammation Induced by a Streptozotocin Rat Model of Alzheimer's Disease. Neurotoxicity research. 2022-08-27. PMID:36029454. |
in the present study, we investigated the effects of andro in the icv-stz model relative to short-term spatial memory (object location test (olt) and y maze test), short-term recognition memory (object recognition test (ort)), locomotor activity (open field test (oft)), expression of amyloid precursor protein (app), and activation of astrocytes (glial fibrillary acidic protein (gfap) expression) and microglia (ionized calcium-binding adapter molecule-1 (iba-1) immunohistochemistry) in the prefrontal cortex (pfc) and hippocampus (hip). |
2022-08-27 |
2023-08-14 |
rat |
| Takayuki Nakajima, Yuki Tanaka, Yusuke Takahashi, Tomohiro Kondo, Shigeo Takenak. The expression and phosphorylation of SMAD3 protein in microglia and astrocytes of the rat hippocampus after transient global cerebral ischemia. Journal of chemical neuroanatomy. 2022-08-27. PMID:36030021. |
the expression and phosphorylation of smad3 protein in microglia and astrocytes of the rat hippocampus after transient global cerebral ischemia. |
2022-08-27 |
2023-08-14 |
rat |
| Risako Fujikawa, Shozo Jinn. Identification of hyper-ramified microglia in the CA1 region of the mouse hippocampus potentially associated with stress resilience. The European journal of neuroscience. 2022-08-26. PMID:36017697. |
identification of hyper-ramified microglia in the ca1 region of the mouse hippocampus potentially associated with stress resilience. |
2022-08-26 |
2023-08-14 |
mouse |
| Risako Fujikawa, Shozo Jinn. Identification of hyper-ramified microglia in the CA1 region of the mouse hippocampus potentially associated with stress resilience. The European journal of neuroscience. 2022-08-26. PMID:36017697. |
the morphological characteristics of microglia in the ca1 region of the dorsal hippocampus in non-stressed controls and resilient mice differed from those in vulnerable mice. |
2022-08-26 |
2023-08-14 |
mouse |