| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Rivas-Arancibia, A E Willing, T Zigova, A I Rodriguez, D W Cahill, P R Sanber. The effects of taurine on hNT neurons transplanted in adult rat striatum. Cell transplantation. vol 9. issue 6. 2001-03-29. PMID:11202562. |
the brains were processed immunohistochemically using antibodies against glial fibrillary acidic protein (gfap), microglia (ox42), and human nuclear matrix antigen (numa). |
2001-03-29 |
2023-08-12 |
human |
| J A Edwards, F Denis, P J Talbo. Activation of glial cells by human coronavirus OC43 infection. Journal of neuroimmunology. vol 108. issue 1-2. 2000-08-25. PMID:10900340. |
this virus also modulated the activity of matrix metalloproteinases-2 and -9 and augmented nitric oxide production in both u-373mg cells and the human microglial cell line chme-5. |
2000-08-25 |
2023-08-12 |
human |
| N E Berman, J K Marcario, C Yong, R Raghavan, L A Raymond, S V Joag, O Narayan, P D Chene. Microglial activation and neurological symptoms in the SIV model of NeuroAIDS: association of MHC-II and MMP-9 expression with behavioral deficits and evoked potential changes. Neurobiology of disease. vol 6. issue 6. 2000-02-17. PMID:10600404. |
brain tissue was examined by immunohistochemistry using two markers of microglia activation, mhc-ii and matrix metalloproteinase-9 (mmp-9). |
2000-02-17 |
2023-08-12 |
monkey |
| A K Cross, M N Woodroof. Chemokine modulation of matrix metalloproteinase and TIMP production in adult rat brain microglia and a human microglial cell line in vitro. Glia. vol 28. issue 3. 1999-12-15. PMID:10559777. |
chemokine modulation of matrix metalloproteinase and timp production in adult rat brain microglia and a human microglial cell line in vitro. |
1999-12-15 |
2023-08-12 |
human |
| S J Hay. Therapeutic approaches to the treatment of neuroinflammatory diseases. Current pharmaceutical design. vol 4. issue 4. 1999-05-10. PMID:10197047. |
a variety of immune system modulators including complement proteins, inflammatory cytokines such il-1 alpha, il-1 beta, il-3, il-6, tnf-alpha, and s100 beta, colony-stimulating factor-1, coagulation proteins and matrix metalloproteases are made by both microglia and astrocytes. |
1999-05-10 |
2023-08-12 |
Not clear |
| Macouillard-Poulletier de Gann, M A Belaud-Rotureau, P Voisin, N Leducq, F Belloc, P Canioni, P Diole. Flow cytometric analysis of mitochondrial activity in situ: application to acetylceramide-induced mitochondrial swelling and apoptosis. Cytometry. vol 33. issue 3. 1999-01-14. PMID:9822344. |
changes in mitochondrial matrix volume were studied both on isolated mitochondria and in situ on chme 5 human microglia and monoblastoid u 937 cells using multiparametric flow cytometric analysis. |
1999-01-14 |
2023-08-12 |
human |
| D N Angelov, M Walther, M Streppel, O Guntinas-Lichius, W F Neiss, R Probstmeier, P Peshev. Tenascin-R is antiadhesive for activated microglia that induce downregulation of the protein after peripheral nerve injury: a new role in neuronal protection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 16. 1998-09-09. PMID:9698315. |
we report that the extracellular matrix protein tenascin-r (tn-r) present in the intact cns is antiadhesive for activated microglia, and its downregulation after facial nerve axotomy may account for the loss of motoneuron protection and subsequent neurodegeneration. |
1998-09-09 |
2023-08-12 |
rat |
| G Guillemin, F D Boussin, J Croitoru, M Franck-Duchenne, R Le Grand, F Lazarini, D Dormon. Obtention and characterization of primary astrocyte and microglial cultures from adult monkey brains. Journal of neuroscience research. vol 49. issue 5. 1997-10-23. PMID:9302079. |
this observation suggests that microglia represent a new potential source of this extracellular matrix protein in the brain. |
1997-10-23 |
2023-08-12 |
monkey |
| Y Ohshige-Hayashi, H Kiyam. Expression of Glycine max (soybean agglutinin) binding molecule in injured motoneurons and its specific localization in the extracellular matrix between injured neurons and microglia. Neuroscience research. vol 27. issue 3. 1997-07-18. PMID:9129185. |
expression of glycine max (soybean agglutinin) binding molecule in injured motoneurons and its specific localization in the extracellular matrix between injured neurons and microglia. |
1997-07-18 |
2023-08-12 |
Not clear |
| P E Gottschall, S De. Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. Neuroimmunomodulation. vol 3. issue 2-3. 1997-05-19. PMID:8945720. |
regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. |
1997-05-19 |
2023-08-12 |
rat |
| P E Gottschall, S De. Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. Neuroimmunomodulation. vol 3. issue 2-3. 1997-05-19. PMID:8945720. |
to this end, we measured the expression of matrix metalloproteinases in cultured rat astrocytes and microglia after treatment with various cytokines. |
1997-05-19 |
2023-08-12 |
rat |
| P E Gottschall, S De. Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. Neuroimmunomodulation. vol 3. issue 2-3. 1997-05-19. PMID:8945720. |
in addition, activated microglia release matrix metalloproteinase-9. |
1997-05-19 |
2023-08-12 |
rat |
| P E Gottschall, S De. Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons. Neuroimmunomodulation. vol 3. issue 2-3. 1997-05-19. PMID:8945720. |
thus, cytokines appear to be potent regulators of matrix metalloproteinase production in astrocytes and microglia. |
1997-05-19 |
2023-08-12 |
rat |
| P E Gottschal. beta-Amyloid induction of gelatinase B secretion in cultured microglia: inhibition by dexamethasone and indomethacin. Neuroreport. vol 7. issue 18. 1997-04-18. PMID:9116244. |
rat microglia in culture were treated with various a beta fragments and gelatinase (glase) activity was determined using gelatin-substrate zymography; the ability of indomethacin (indo) and dexamethasone (dex) to inhibit a beta-stimulated glase, specifically matrix metalloproteinase-9 (mmp-9), activity was also evaluated. |
1997-04-18 |
2023-08-12 |
rat |
| H Wilms, D Hartmann, J Siever. Ramification of microglia, monocytes and macrophages in vitro: influences of various epithelial and mesenchymal cells and their conditioned media. Cell and tissue research. vol 287. issue 3. 1997-04-10. PMID:9023076. |
likewise, microglia remained amoeboid, when incubated on several constituents of the extracellular matrix. |
1997-04-10 |
2023-08-12 |
Not clear |
| R A Washington, B Becher, R Balabanov, J Antel, P Dore-Duff. Expression of the activation marker urokinase plasminogen-activator receptor in cultured human central nervous system microglia. Journal of neuroscience research. vol 45. issue 4. 1997-01-10. PMID:8872899. |
the ability of microglia to migrate through central nervous system (cns) tissue requires proteolytic degradation of components of the extracellular matrix. |
1997-01-10 |
2023-08-12 |
human |
| J C Möller, M A Klein, S Haas, L L Jones, G W Kreutzberg, G Raivic. Regulation of thrombospondin in the regenerating mouse facial motor nucleus. Glia. vol 17. issue 2. 1996-12-04. PMID:8776579. |
since thrombospondin is a multimodal extracellular matrix protein with a variety of cell attachment sites, thrombospondin might serve to link microglia and injured neurons, followed by microglial proliferation and removal of the neuronal debris. |
1996-12-04 |
2023-08-12 |
mouse |
| J El Khoury, S E Hickman, C A Thomas, L Cao, S C Silverstein, J D Loik. Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils. Nature. vol 382. issue 6593. 1996-09-23. PMID:8751442. |
mononuclear phagocytes, including microglia, express scavenger receptors that mediate endocytosis of oxidized low-density lipoproteins, and adhesion to glucose-modified extra-cellular matrix proteins. |
1996-09-23 |
2023-08-12 |
human |
| S Petanceska, P Canoll, L A Dev. Expression of rat cathepsin S in phagocytic cells. The Journal of biological chemistry. vol 271. issue 8. 1996-06-21. PMID:8626791. |
this possibility is further supported by the finding that cathepsin s degrades a number of extracellular matrix molecules at neutral ph and by the finding that inflammatory mediators stimulate its secretion from the microglia and macrophages. |
1996-06-21 |
2023-08-12 |
rat |
| P E Gottschall, X Yu, B Bin. Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture. Journal of neuroscience research. vol 42. issue 3. 1996-03-20. PMID:8583501. |
increased production of gelatinase b (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture. |
1996-03-20 |
2023-08-12 |
rat |