| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhi-Kun Qiu, De-Sheng Zhong, Jia-Li He, Xu Liu, Ji-Sheng Chen, Hong Ni. The anxiolytic-like effects of puerarin are associated with the changes of monoaminergic neurotransmitters and biosynthesis of allopregnanolone in the brain. Metabolic brain disease. vol 33. issue 1. 2019-01-31. PMID:29101599. |
moreover, the present study also found that consistent with ser, the levels of allopregnanolone and serotonin (5-ht) in the prefrontal cortex and hippocampus were increased by puerarin (60 and 120 mg/kg, i.g. |
2019-01-31 |
2023-08-13 |
Not clear |
| Huali Wu, Qiongzhen Liu, Praveen Kumar Kalavagunta, Qiaoling Huang, Wenting Lv, Xiaohong An, Haijuan Chen, Tao Wang, Rakotomalala Manda Heriniaina, Tong Qiao, Jing Shan. Normal diet Vs High fat diet - A comparative study: Behavioral and neuroimmunological changes in adolescent male mice. Metabolic brain disease. vol 33. issue 1. 2019-01-31. PMID:29101600. |
at the end of 6th week hippocampal analysis revealed the differences in morphology (reduced nissl positive neurons and decreased the 5-ht |
2019-01-31 |
2023-08-13 |
mouse |
| F Sh Shagiakhmetov, P K Anokhin, A O Popova, I Yu Shamakin. [A profile of antidepressive effects of agomelatine and a current view on the mechanism of its action]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 117. issue 12. 2019-01-29. PMID:29376995. |
besides the effect on suprachiasmatic nucleus, a relevant role in the mechanism of action of agomelatine plays its special functionally selective (with regard to intracellular signaling pathways) interaction with heteromeric complexes of serotonin 5-НТ2С and melatonin mt2 receptors in the hippocampus and cerebral cortex. |
2019-01-29 |
2023-08-13 |
Not clear |
| Shengbing Liu, Shuiling Xu, Zhijian Wang, Yanjun Guo, Weiwei Pan, Zhongfei She. Anti-Depressant-Like Effect of Sinomenine on Chronic Unpredictable Mild Stress-Induced Depression in a Mouse Model. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-01-07. PMID:30362468. |
the levels of norepinephrine (ne), 5-hydroxytryptamine (5-ht), and proinflammatory cytokines (interleukin-1β [il-1β] interleukin-6 [il-6], and tumor necrosis factor-α [tnf-α]) in the hippocampus of mice were detected by elisa assay. |
2019-01-07 |
2023-08-13 |
mouse |
| Shengbing Liu, Shuiling Xu, Zhijian Wang, Yanjun Guo, Weiwei Pan, Zhongfei She. Anti-Depressant-Like Effect of Sinomenine on Chronic Unpredictable Mild Stress-Induced Depression in a Mouse Model. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-01-07. PMID:30362468. |
in addition, sin decreased cums-induced reduction in the concentrations of ne and 5-ht in the hippocampus of mice. |
2019-01-07 |
2023-08-13 |
mouse |
| Nayara Pestana-Oliveira, Bruna Kalil, Cristiane Mota Leite, Ruither Oliveira Gomes Carolino, Lucas Kniess Debarba, Lucila Leico Kagohara Elias, José Antunes-Rodrigues, Janete A Anselmo-Franc. Effects of Estrogen Therapy on the Serotonergic System in an Animal Model of Perimenopause Induced by 4-Vinylcyclohexen Diepoxide (VCD). eNeuro. vol 5. issue 1. 2019-01-02. PMID:29362726. |
blood was collected for hormone measurement, the brains were removed and dorsal raphe nucleus (drn), hippocampus (hpc), and amygdala (amy) punched out for serotonin (5-ht), estrogen receptor β (erβ), and progesterone receptor (pr) mrna level measurements. |
2019-01-02 |
2023-08-13 |
rat |
| Mei Huang, Sunoh Kwon, Lakshmi Rajagopal, Wenqi He, Herbert Y Meltze. 5-HT Psychopharmacology. vol 235. issue 10. 2018-12-31. PMID:30066135. |
5-ht the effect of atypical antipsychotic drugs (aapds), e.g., lurasidone, to improve cognitive impairment associated with schizophrenia (cias), has been suggested to be due, in part, to enhancing release of dopamine (da), acetylcholine (ach), and glutamate (glu) in cortex and hippocampus. |
2018-12-31 |
2023-08-13 |
Not clear |
| M G Gottschalk, P Mortas, M Haman, S Ozcan, B Biemans, S Bah. Fluoxetine, not donepezil, reverses anhedonia, cognitive dysfunctions and hippocampal proteome changes during repeated social defeat exposure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 1. 2018-12-11. PMID:29174946. |
we evaluated the behavioural and molecular effects of a selective serotonin re-uptake inhibitor (ssri, fluoxetine) and an acetylcholinesterase inhibitor (achei, donepezil) on emotional-cognitive endophenotypes of depression and the hippocampal proteome. |
2018-12-11 |
2023-08-13 |
Not clear |
| Arnold Gutierrez, Michael T Williams, Charles V Vorhee. A Single High Dose of Methamphetamine Reduces Monoamines and Impairs Egocentric and Allocentric Learning and Memory in Adult Male Rats. Neurotoxicity research. vol 33. issue 3. 2018-12-11. PMID:29427284. |
ma-treated rats had persistent dopamine and serotonin reductions in the neostriatum and nucleus accumbens, and serotonin reductions in the hippocampus of the same magnitude as in repetitive treatment models. |
2018-12-11 |
2023-08-13 |
rat |
| Yongtao Bai, Lihua Song, Guoliang Dai, Meijuan Xu, Lijing Zhu, Weidong Zhang, Wen Jing, Wenzheng J. Antidepressant effects of magnolol in a mouse model of depression induced by chronic corticosterone injection. Steroids. vol 135. 2018-12-11. PMID:29555480. |
moreover, we also found that cort levels in serum were significantly increased, along with the decrease of brain-derived neurotrophic factor (bdnf) mrna, bdnf protein, 5-hydroxytryptamine (5-ht) and norepinephrine (ne) levels in the hippocampus. |
2018-12-11 |
2023-08-13 |
mouse |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
the data collected here confirms that re-exposure to the context of morphine administration after the withdrawal period increases the level of 50-khz usvs and this contextual response is associated with elevated serotonin concentrations in amygdala, hippocampus and mpfc and with increased glu/gln ratio in nucleus accumbens. |
2018-12-11 |
2023-08-13 |
rat |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
the concentration of serotonin increases simultaneously in amygdala, nucleus accumbens and hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Adam Hamed, Miron Bartosz Kurs. Inter-individual differences in serotonin and glutamate co-transmission reflect differentiation in context-induced conditioned 50-kHz USVs response after morphine withdrawal. Brain structure & function. vol 223. issue 7. 2018-12-11. PMID:29774428. |
moreover, 5-ht concentration in amygdala is bound up with glutamate level in this structure as well as in hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Matthew J Robson, Meagan A Quinlan, Kara Gross Margolis, Paula A Gajewski-Kurdziel, Jeremy Veenstra-VanderWeele, Michael D Gershon, D Martin Watterson, Randy D Blakel. p38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 43. 2018-12-11. PMID:30297392. |
mice expressing the most common of these variants (sert ala56) exhibit hyperserotonemia, a biomarker observed in asd subjects, as well as p38 mapk-dependent sert hyperphosphorylation, elevated hippocampal 5-ht clearance, hypersensitivity of cns 5-ht |
2018-12-11 |
2023-08-13 |
mouse |
| Benneth Ben-Azu, Adegbuyi Oladele Aderibigbe, Aya-Ebi Okubo Eneni, Abayomi Mayowa Ajayi, Solomon Umukoro, Ezekiel O Iwalew. Morin Attenuates Neurochemical Changes and Increased Oxidative/Nitrergic Stress in Brains of Mice Exposed to Ketamine: Prevention and Reversal of Schizophrenia-Like Symptoms. Neurochemical research. vol 43. issue 9. 2018-11-21. PMID:29956036. |
thereafter, the brain levels of dopamine, glutamate, 5-hydroxytryptamine and acetyl-cholinesterase, as well as biomarkers of oxidative/nitrergic stress were measured in the striatum, prefrontal-cortex (pfc) and hippocampus (hc). |
2018-11-21 |
2023-08-13 |
mouse |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in wistar rats. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
however, little is known about the effect of sequential exposure to ethanol and meth on glutamate, dopamine and serotonin tissue content in striatum and hippocampus. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
in the hippocampus, sequential exposure to ethanol and meth decreased serotonin tissue content as compared to the group that was exposed to ethanol alone. |
2018-11-13 |
2023-08-13 |
rat |
| Atiah H Almalki, Sujan C Das, Fahad S Alshehri, Yusuf S Althobaiti, Youssef Sar. Effects of sequential ethanol exposure and repeated high-dose methamphetamine on striatal and hippocampal dopamine, serotonin and glutamate tissue content in Wistar rats. Neuroscience letters. vol 665. 2018-11-13. PMID:29174641. |
however, this study showed that ethanol has no additive effect to meth on tissue content of dopamine and serotonin as compared to meth in the striatum and hippocampus. |
2018-11-13 |
2023-08-13 |
rat |
| Ning Jiang, Lin-Xi Fan, Yu-Jie Yang, Xin-Min Liu, Hai-Ying Lin, Li Gao, Qiong Wan. [Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 2. 2018-10-30. PMID:28435974. |
in addition, in the hippocampus and cortex, the levels of 5-ht and da were significantly decreased in the cums group compared with the control group (p < 0.05). |
2018-10-30 |
2023-08-13 |
mouse |