| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Morici, G Cicuttin, A Silva, F T Gallo, M Miranda, M Beluscio, C Zold, P Bekinschtein, N V Weisstau. Serotonin type 2a receptor in the prefrontal cortex controls perirhinal cortex excitability during object recognition memory recall. Neuroscience. 2022-05-21. PMID:35597334. |
serotonin type 2a receptor in the prefrontal cortex controls perirhinal cortex excitability during object recognition memory recall. |
2022-05-21 |
2023-08-13 |
Not clear |
| Jinxing Li, Fangfang Pu, Chenrui Peng, Yimei Wang, Yujie Zhang, Simou Wu, Silu Wang, Xi Shen, Ruyue Cheng, Fang H. Antibiotic cocktail-induced gut microbiota depletion in different stages could cause host cognitive impairment and emotional disorders in adulthood in different manners. Neurobiology of disease. 2022-05-19. PMID:35588989. |
gut microbiota depletion in adolescence resulted in anxiety-like behaviors, short-term memory decline, decreased serum interferon-γ (ifn-γ), mrna expression of 5-hydroxytryptamine receptor 1a, and neuropeptide y receptor y2 in the prefrontal cortex of adult mice. |
2022-05-19 |
2023-08-13 |
mouse |
| Keren Nitzan, Dekel David, Motty Franko, Roni Toledano, Sharon Fidelman, Yaarit Simchon Tenenbaum, Maya Blonder, Shir Armoza-Eilat, Alon Shamir, Moshe Rehavi, Yair Ben-Chaim, Ravid Doro. Anxiolytic and antidepressants' effect of Crataegus pinnatifida (Shan Zha): biochemical mechanisms. Translational psychiatry. vol 12. issue 1. 2022-05-19. PMID:35589704. |
chronic treatment with shan zha did not alter serotonin transporter levels in the pfc, as opposed to escitalopram treatment. |
2022-05-19 |
2023-08-13 |
mouse |
| Christopher J O'Connell, Evan L Reeder, Roman A Caceres, Sean M Collins, Kyla Q Chilton, Gary A Gudelsky, Matthew J Robso. Closed Head Traumatic Brain Injury Drives Protracted Inflammation and Remodeling of Serotonergic Architecture in the Dorsal Raphe Nucleus. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554019. |
no effect of mtbi on 5-ht or 5hiaa levels were found in prefrontal cortex (pfc) or somatosensory cortex (ssc), areas of high 5-ht innervation. |
2022-05-13 |
2023-08-13 |
mouse |
| Tara P Cominski, Victoria Stiritz, Kevin D Bec. The Effects of Mild Traumatic Brain Injury (mTBI) on Serotonergic Gene Expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554362. |
the hypothesis states that mtbi leads to altered expression of serotonin related genes in the raphe nuclei and/or raphe nuclei target regions including the prefrontal cortex, frontal cortex, and hippocampus. |
2022-05-13 |
2023-08-13 |
human |
| Nikhil M Urs, Sharonda Harris, Sara M Green, Mayank M Kuma. A Role for Cortical Dopamine in the Paradoxical Calming Effects of Psychostimulants. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554609. |
our ex vivo efflux experiments reveal that ne transporter (net) blocker desipramine elevates both norepinephrine and dopamine but not serotonin levels, in pfc tissue slices from wild-type and dat-ko but not net-ko mice. |
2022-05-13 |
2023-08-13 |
mouse |
| Nikhil M Urs, Sharonda Harris, Sara M Green, Mayank M Kuma. A Role for Cortical Dopamine in the Paradoxical Calming Effects of Psychostimulants. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554609. |
together, these data suggest that elevation of pfc dopamine and not norepinephrine or serotonin as a convergent mechanism for the paradoxical psychostimulant effects observed in adhd therapy. |
2022-05-13 |
2023-08-13 |
mouse |
| Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies. 2022-05-09. PMID:35531602. |
these behavioral changes were accompanied by reduced dopamine in the prefrontal cortex (pfc), norepinephrine in the amygdala, and 5-hydroxytryptamine (5-ht) in the dorsal midbrain (dm), pfc, and amygdala where 5-ht neurons project from the dm. |
2022-05-09 |
2023-08-13 |
Not clear |
| Tetsuo Ono, Kodai Hino, Tomoko Kimura, Yasuhiro Uchimura, Takashi Ashihara, Takako Higa, Hideto Kojima, Takashi Murakami, Jun Udagaw. Excessive folic acid intake combined with undernutrition during gestation alters offspring behavior and brain monoamine profiles. Congenital anomalies. 2022-05-09. PMID:35531602. |
canonical discriminant analysis, including dopamine and dopac concentrations in the pfc, norepinephrine concentrations in the pfc, amygdala, and pons, and 5-ht and 5-hiaa concentrations in the amygdala and dm, correctly classified 73.5% of the offspring in con, ff, un, and un-ff groups. |
2022-05-09 |
2023-08-13 |
Not clear |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
the ability of cholecalciferol to elicit an antidepressant-like effect and to modulate serotonin levels in the hippocampus and prefrontal cortex of mice subjected to chronic unpredictable stress (cus) was also investigated. |
2022-04-18 |
2023-08-13 |
mouse |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
additionally, cus protocol (21 days) induced depressive-like behavior in the tail suspension test and decreased serotonin levels in the prefrontal cortex and hippocampus of mice. |
2022-04-18 |
2023-08-13 |
mouse |
| Vivian B Neis, Isabel Werle, Morgana Moretti, Priscila B Rosa, Anderson Camargo, Yasmim de O Dalsenter, Nicolle Platt, Axel F Rosado, William D Engel, Gudrian Ricardo L de Almeida, Ingrid Selhorst, Alcir Luiz Dafre, Ana Lúcia S Rodrigue. Involvement of serotonergic neurotransmission in the antidepressant-like effect elicited by cholecalciferol in the chronic unpredictable stress model in mice. Metabolic brain disease. 2022-04-18. PMID:35435610. |
cholecalciferol was also effective to abrogate cus-induced reduction on serotonin levels in the prefrontal cortex, but not in the hippocampus. |
2022-04-18 |
2023-08-13 |
mouse |
| Runlong Zhao, Yalin Zhou, Hanxu Shi, Wanyun Ye, Ying Lyu, Zhang Wen, Rui Li, Yajun X. Effect of Gestational Diabetes on Postpartum Depression-like Behavior in Rats and Its Mechanism. Nutrients. vol 14. issue 6. 2022-03-26. PMID:35334886. |
the hpa axis hormone did not show the typical stress state of depression, but the level of 5-ht decreased significantly in serum, prefrontal cortex and hippocampus, and the kyn/trp ratio increased significantly in serum and prefrontal cortex, implying the switch of the tryptophan (trp) metabolism from the 5-ht pathway to the kynurenine (kyn) pathway. |
2022-03-26 |
2023-08-13 |
rat |
| Kateryna Murlanova, Netanela Cohen, Anna Pinkus, Liudmila Vinnikova, Mikhail Pletnikov, Michael Kirby, Jonathan Gorelick, Elyashiv Drori, Albert Pinhaso. Antidepressant-like effects of a chlorogenic acid- and cynarine-enriched fraction from Dittrichia viscosa root extract. Scientific reports. vol 12. issue 1. 2022-03-08. PMID:35256610. |
neurochemical profiling for 5-hydroxytryptamine (5-ht) and its primary metabolite, 5-hydroxyindoleacetic acid (5-hiaa), in prefrontal cortex and hippocampus of "k"-treated mice showed reduction in 5-hiaa, indicative of either serotonin uptake transporter or monoamine oxidase-a inhibition, as well as slight increases in 5-ht content. |
2022-03-08 |
2023-08-13 |
mouse |
| Joanna Kowalczyk, Modestos Nakos-Bimpos, Alexia Polissidis, Christina Dalla, Nikolaos Kokras, Krystyna Skalicka-Woźniak, Barbara Budzyńsk. Imperatorin Influences Depressive-like Behaviors: A Preclinical Study on Behavioral and Neurochemical Sex Differences. Molecules (Basel, Switzerland). vol 27. issue 4. 2022-02-25. PMID:35208969. |
the hplc analysis demonstrated that serotonin levels in the prefrontal cortex of females decreased with the middle dose of imperatorin (5 mg/kg), while in the male prefrontal cortex, the lower dose (1 mg/kg) boosted serotonin levels. |
2022-02-25 |
2023-08-13 |
mouse |
| Sharonda S Harris, Sara M Green, Mayank Kumar, Nikhil M Ur. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Scientific reports. vol 12. issue 1. 2022-02-25. PMID:35210489. |
our ex vivo efflux experiments reveal that the ne transporter (net) blocker desipramine elevates both norepinephrine (ne) and dopamine (da), but not 5-ht levels, in pfc tissue slices from wild-type (wt) and dat-ko, but not net-ko mice. |
2022-02-25 |
2023-08-13 |
mouse |
| Sharonda S Harris, Sara M Green, Mayank Kumar, Nikhil M Ur. A role for cortical dopamine in the paradoxical calming effects of psychostimulants. Scientific reports. vol 12. issue 1. 2022-02-25. PMID:35210489. |
together, these data suggest elevation of pfc da and not ne or 5-ht, as a convergent mechanism for the paradoxical effects of psychostimulants observed in adhd therapy. |
2022-02-25 |
2023-08-13 |
mouse |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
here we aimed to examine the effects of the para- chlorophenylalanine (pcpa; 100mg/kg/daily, s.c during the postnatal days 10-20), a reversible inhibitor of 5-ht synthesis, on the serotonin level of the hippocampal and prefrontal cortex. |
2022-02-19 |
2023-08-13 |
rat |
| Safa Ghaheri, Ali Niapour, Nona Sakhaie, Farshid Sadegzadeh, Hakimeh Saadat. Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2022-02-19. PMID:35181916. |
our results indicated that the administration of pcpa led to a decrease in serotonin levels in the hippocampus and prefrontal cortex. |
2022-02-19 |
2023-08-13 |
rat |
| Mohammed E Choudhury, Kanta Mikami, Yuiko Nakanishi, Taisei Matsuura, Ryo Utsunomiya, Hajime Yano, Madoka Kubo, Rina Ando, Jun Iwanami, Masakatsu Yamashita, Masahiro Nagai, Junya Tanak. Insomnia and depressive behavior of MyD88-deficient mice: Relationships with altered microglial functions. Journal of neuroimmunology. vol 363. 2021-12-31. PMID:34971898. |
we determined monoamines in the prefrontal cortex (pfc) using high-performance liquid chromatography and observed a decreased content of serotonin in the pfc of myd88-ko mice. |
2021-12-31 |
2023-08-13 |
mouse |