| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brett I Cohe. The significance of ammonia/gamma-aminobutyric acid (GABA) ratio for normality and liver disorders. Medical hypotheses. vol 59. issue 6. 2003-06-12. PMID:12445521. |
cohen has illustrated that extremely high gamma-aminobutyric acid (gaba) levels in the urine and blood and high plasma ammonia were observed for an autistic male child diagnosed with infantile autism. |
2003-06-12 |
2023-08-12 |
human |
| S T Sinkkonen, G E Homanics, E R Korp. Mouse models of Angelman syndrome, a neurodevelopmental disorder, display different brain regional GABA(A) receptor alterations. Neuroscience letters. vol 340. issue 3. 2003-05-30. PMID:12672542. |
it results from a maternal deletion of human chromosome 15q11-13 containing two candidate genes e6-p ubiquitin-protein ligase (ube3a) and gaba(a) receptor beta3 subunit (gabrb3), the latter of which has been also linked to autism. |
2003-05-30 |
2023-08-12 |
mouse |
| Dirk Dhossche, Heather Applegate, Ann Abraham, Paul Maertens, Lorna Bland, Aladar Bencsath, José Martine. Elevated plasma gamma-aminobutyric acid (GABA) levels in autistic youngsters: stimulus for a GABA hypothesis of autism. Medical science monitor : international medical journal of experimental and clinical research. vol 8. issue 8. 2003-03-21. PMID:12165753. |
elevated plasma gamma-aminobutyric acid (gaba) levels in autistic youngsters: stimulus for a gaba hypothesis of autism. |
2003-03-21 |
2023-08-12 |
Not clear |
| G J Blatt, C M Fitzgerald, J T Guptill, A B Booker, T L Kemper, M L Bauma. Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study. Journal of autism and developmental disorders. vol 31. issue 6. 2002-07-16. PMID:11814263. |
data from these single concentration ligand binding studies indicate that the gabaergic receptor system (3[h]-flunitrazepam labeled benzodiazepine binding sites and 3[h]-muscimol labeled gaba(a) receptors) is significantly reduced in high binding regions, marking for the first time an abnormality in the gaba system in autism. |
2002-07-16 |
2023-08-12 |
Not clear |
| E L Nurmi, Y Bradford, Y Chen, J Hall, B Arnone, M B Gardiner, H B Hutcheson, J R Gilbert, M A Pericak-Vance, S A Copeland-Yates, R C Michaelis, T H Wassink, S L Santangelo, V C Sheffield, J Piven, S E Folstein, J L Haines, J S Sutcliff. Linkage disequilibrium at the Angelman syndrome gene UBE3A in autism families. Genomics. vol 77. issue 1-2. 2001-12-04. PMID:11543639. |
we have screened the families of the collaborative linkage study of autism for several markers spanning a candidate region covering approximately 2 mb and including the angelman syndrome gene (ube3a) and a cluster of gamma-aminobutyric acid (gaba(a)) receptor subunit genes (gabrb3, gabra5, and gabrg3). |
2001-12-04 |
2023-08-12 |
Not clear |
| E Maestrini, C Lai, A Marlow, N Matthews, S Wallace, A Bailey, E H Cook, D E Weeks, A P Monac. Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families. The International Molecular Genetic Study of Autism Consortium. American journal of medical genetics. vol 88. issue 5. 1999-11-17. PMID:10490705. |
serotonin transporter (5-htt) and gamma-aminobutyric acid receptor subunit beta3 (gabrb3) gene polymorphisms are not associated with autism in the imgsa families. |
1999-11-17 |
2023-08-12 |
Not clear |
| E Maestrini, C Lai, A Marlow, N Matthews, S Wallace, A Bailey, E H Cook, D E Weeks, A P Monac. Serotonin transporter (5-HTT) and gamma-aminobutyric acid receptor subunit beta3 (GABRB3) gene polymorphisms are not associated with autism in the IMGSA families. The International Molecular Genetic Study of Autism Consortium. American journal of medical genetics. vol 88. issue 5. 1999-11-17. PMID:10490705. |
previous studies have suggested that the serotonin transporter (5-htt) gene and the gamma-aminobutyric acid receptor subunit beta3 (gabrb3) gene, or other genes in the 15q11-q13 region, are possibly involved in susceptibility to autism. |
1999-11-17 |
2023-08-12 |
Not clear |