| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mamoru Tochigi, Chieko Kato, Shinko Koishi, Yuki Kawakubo, Kenji Yamamoto, Hideo Matsumoto, Ohiko Hashimoto, Soo-Yung Kim, Keiichiro Watanabe, Yukiko Kano, Eiji Nanba, Nobumasa Kato, Tsukasa Sasak. No evidence for significant association between GABA receptor genes in chromosome 15q11-q13 and autism in a Japanese population. Journal of human genetics. vol 52. issue 12. 2008-02-06. PMID:17957331. |
in this study, we first investigated the association between the gaba receptor genes and autism in a japanese population by analyzing 11 single nucleotide polymorphisms (snps). |
2008-02-06 |
2023-08-12 |
human |
| Mamoru Tochigi, Chieko Kato, Shinko Koishi, Yuki Kawakubo, Kenji Yamamoto, Hideo Matsumoto, Ohiko Hashimoto, Soo-Yung Kim, Keiichiro Watanabe, Yukiko Kano, Eiji Nanba, Nobumasa Kato, Tsukasa Sasak. No evidence for significant association between GABA receptor genes in chromosome 15q11-q13 and autism in a Japanese population. Journal of human genetics. vol 52. issue 12. 2008-02-06. PMID:17957331. |
thus, this study provides no positive evidence of an association between the gaba receptor genes and autism in a japanese population. |
2008-02-06 |
2023-08-12 |
human |
| Jane Yip, Jean-Jacques Soghomonian, Gene J Blat. Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications. Acta neuropathologica. vol 113. issue 5. 2007-08-31. PMID:17235515. |
the recent identification of decreased protein levels of glutamate decarboxylase (gad) 65 and 67 isoforms in the autistic cerebellar tissue raises the possibility that abnormal regulation of gaba production in individual neurons may contribute to the clinical features of autism. |
2007-08-31 |
2023-08-12 |
Not clear |
| Robert Delon. GABA(A) receptor alpha5 subunit as a candidate gene for autism and bipolar disorder: a proposed endophenotype with parent-of-origin and gain-of-function features,with or without oculocutaneous albinism. Autism : the international journal of research and practice. vol 11. issue 2. 2007-07-03. PMID:17353214. |
gaba(a) receptor alpha5 subunit as a candidate gene for autism and bipolar disorder: a proposed endophenotype with parent-of-origin and gain-of-function features,with or without oculocutaneous albinism. |
2007-07-03 |
2023-08-12 |
Not clear |
| Soon Ae Kim, Jin Hee Kim, Mira Park, In Hee Cho, Hee Jeong Yo. Association of GABRB3 polymorphisms with autism spectrum disorders in Korean trios. Neuropsychobiology. vol 54. issue 3. 2007-05-08. PMID:17230033. |
the association and linkage study for the gamma-aminobutyric acid type a receptor beta3 subunit gene (gabrb3), located within the chromosome 15q11-q13 autism candidate region, and asd have been evaluated. |
2007-05-08 |
2023-08-12 |
Not clear |
| James E Crandall, Deirdre M McCarthy, Kiyomi Y Araki, John R Sims, Jia-Qian Ren, Pradeep G Bhid. Dopamine receptor activation modulates GABA neuron migration from the basal forebrain to the cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 14. 2007-05-02. PMID:17409246. |
the intimate relationship between dopamine and gaba neuron development revealed here may offer novel insights into developmental disorders such as schizophrenia, attention deficit or autism, and fetal cocaine exposure, all of which are associated with dopamine and gaba imbalance. |
2007-05-02 |
2023-08-12 |
mouse |
| Ann L Collins, Deqiong Ma, Patrice L Whitehead, Eden R Martin, Harry H Wright, Ruth K Abramson, John P Hussman, Jonathan L Haines, Michael L Cuccaro, John R Gilbert, Margaret A Pericak-Vanc. Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Neurogenetics. vol 7. issue 3. 2007-01-12. PMID:16770606. |
investigation of autism and gaba receptor subunit genes in multiple ethnic groups. |
2007-01-12 |
2023-08-12 |
Not clear |
| Ann L Collins, Deqiong Ma, Patrice L Whitehead, Eden R Martin, Harry H Wright, Ruth K Abramson, John P Hussman, Jonathan L Haines, Michael L Cuccaro, John R Gilbert, Margaret A Pericak-Vanc. Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Neurogenetics. vol 7. issue 3. 2007-01-12. PMID:16770606. |
multiple lines of evidence, including alterations in levels of gaba and gaba receptors in autistic patients, indicate that the gabaergic system, which is responsible for synaptic inhibition in the adult brain, may be involved in autism. |
2007-01-12 |
2023-08-12 |
Not clear |
| Ann L Collins, Deqiong Ma, Patrice L Whitehead, Eden R Martin, Harry H Wright, Ruth K Abramson, John P Hussman, Jonathan L Haines, Michael L Cuccaro, John R Gilbert, Margaret A Pericak-Vanc. Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Neurogenetics. vol 7. issue 3. 2007-01-12. PMID:16770606. |
previous studies in our lab indicated association of noncoding single nucleotide polymorphisms (snps) within a gaba receptor subunit gene on chromosome 4, gabra4, and interaction between snps in gabra4 and gabrb1 (also on chromosome 4), within caucasian autism patients. |
2007-01-12 |
2023-08-12 |
Not clear |
| Schahram Akbarian, Hsien-Sung Huan. Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain research reviews. vol 52. issue 2. 2006-11-14. PMID:16759710. |
the 67 and 65 kda isoforms of glutamic acid decarboxylase, the key enzymes for gaba biosynthesis, are expressed at altered levels in postmortem brain of subjects diagnosed with schizophrenia and related disorders, including autism and bipolar illness. |
2006-11-14 |
2023-08-12 |
human |
| Dirk Marcel Dhossche, Amitta Shah, Lorna Win. Blueprints for the assessment, treatment, and future study of catatonia in autism spectrum disorders. International review of neurobiology. vol 72. 2006-07-14. PMID:16697303. |
finally, the role of gamma-aminobutyric acid (gaba) dysfunction in autism, catatonia, and abnormal stress responses in these disorders should be further assessed. |
2006-07-14 |
2023-08-12 |
Not clear |
| A E Ashley-Koch, H Mei, J Jaworski, D Q Ma, M D Ritchie, M M Menold, G R Delong, R K Abramson, H H Wright, J P Hussman, M L Cuccaro, J R Gilbert, E R Martin, M A Pericak-Vanc. An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder. Annals of human genetics. vol 70. issue Pt 3. 2006-06-19. PMID:16674551. |
gaba receptor subunit genes do not significantly interact to contribute to autism risk in our overall data set. |
2006-06-19 |
2023-08-12 |
Not clear |
| Dirk M Dhossche, Yaru Song, Yiming Li. Is there a connection between autism, Prader-Willi syndrome, catatonia, and GABA? International review of neurobiology. vol 71. 2006-03-29. PMID:16512352. |
is there a connection between autism, prader-willi syndrome, catatonia, and gaba? |
2006-03-29 |
2023-08-12 |
Not clear |
| D Q Ma, P L Whitehead, M M Menold, E R Martin, A E Ashley-Koch, H Mei, M D Ritchie, G R Delong, R K Abramson, H H Wright, M L Cuccaro, J P Hussman, J R Gilbert, M A Pericak-Vanc. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. American journal of human genetics. vol 77. issue 3. 2006-02-06. PMID:16080114. |
identification of significant association and gene-gene interaction of gaba receptor subunit genes in autism. |
2006-02-06 |
2023-08-12 |
Not clear |
| D Q Ma, P L Whitehead, M M Menold, E R Martin, A E Ashley-Koch, H Mei, M D Ritchie, G R Delong, R K Abramson, H H Wright, M L Cuccaro, J P Hussman, J R Gilbert, M A Pericak-Vanc. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. American journal of human genetics. vol 77. issue 3. 2006-02-06. PMID:16080114. |
gamma-aminobutyric acid (gaba), the primary inhibitory neurotransmitter in the adult brain, has been implicated in autism etiology. |
2006-02-06 |
2023-08-12 |
Not clear |
| D Q Ma, P L Whitehead, M M Menold, E R Martin, A E Ashley-Koch, H Mei, M D Ritchie, G R Delong, R K Abramson, H H Wright, M L Cuccaro, J P Hussman, J R Gilbert, M A Pericak-Vanc. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. American journal of human genetics. vol 77. issue 3. 2006-02-06. PMID:16080114. |
fourteen known autosomal gaba receptor subunit genes were studied to look for the genes associated with autism and their possible interactions. |
2006-02-06 |
2023-08-12 |
Not clear |
| D Q Ma, P L Whitehead, M M Menold, E R Martin, A E Ashley-Koch, H Mei, M D Ritchie, G R Delong, R K Abramson, H H Wright, M L Cuccaro, J P Hussman, J R Gilbert, M A Pericak-Vanc. Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism. American journal of human genetics. vol 77. issue 3. 2006-02-06. PMID:16080114. |
these results support the hypothesis that gaba receptor subunit genes are involved in autism, most likely via complex gene-gene interactions. |
2006-02-06 |
2023-08-12 |
Not clear |
| Dirk M Dhossche, Sara Stanfil. Could ECT be effective in autism? Medical hypotheses. vol 63. issue 3. 2005-02-10. PMID:15288351. |
a gaba theory of autism and catatonia may be pivotal. |
2005-02-10 |
2023-08-12 |
mouse |
| Jacob L McCauley, Lana M Olson, Ryan Delahanty, Taneem Amin, Erika L Nurmi, Edward L Organ, Michelle M Jacobs, Susan E Folstein, Jonathan L Haines, James S Sutcliff. A linkage disequilibrium map of the 1-Mb 15q12 GABA(A) receptor subunit cluster and association to autism. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 131B. issue 1. 2005-02-08. PMID:15389768. |
a linkage disequilibrium map of the 1-mb 15q12 gaba(a) receptor subunit cluster and association to autism. |
2005-02-08 |
2023-08-12 |
Not clear |
| Jacob L McCauley, Lana M Olson, Ryan Delahanty, Taneem Amin, Erika L Nurmi, Edward L Organ, Michelle M Jacobs, Susan E Folstein, Jonathan L Haines, James S Sutcliff. A linkage disequilibrium map of the 1-Mb 15q12 GABA(A) receptor subunit cluster and association to autism. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 131B. issue 1. 2005-02-08. PMID:15389768. |
these studies support the existence of one or more autism risk alleles in the gaba(a) receptor subunit cluster on 15q12 and have implications for analysis of ld and association in regions with high local recombination. |
2005-02-08 |
2023-08-12 |
Not clear |