| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masami Masuda-Suzukake, Genjiro Suzuki, Masato Hosokawa, Takashi Nonaka, Michel Goedert, Masato Hasegaw. Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice. Brain communications. vol 2. issue 2. 2021-01-10. PMID:33005889. |
accumulation of assembled tau protein in the central nervous system is characteristic of alzheimer's disease and several other neurodegenerative diseases, called tauopathies. |
2021-01-10 |
2023-08-13 |
mouse |
| Robert Y K Lai, Charles R Harrington, Claude M Wischi. Erratum: Lai, R.Y.K.; Harrington, C.R.; Wischik, C.M. Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease. Biomolecules 2016, 6, 19. Biomolecules. vol 6. issue 3. 2021-01-09. PMID:27529285. |
absence of a role for phosphorylation in the tau pathology of alzheimer's disease. |
2021-01-09 |
2023-08-13 |
Not clear |
| Feng Zhang, Rujia Zhong, Song Li, Zhenfa Fu, Cheng Cheng, Huaibin Cai, Weidong L. Acute Hypoxia Induced an Imbalanced M1/M2 Activation of Microglia through NF-κB Signaling in Alzheimer's Disease Mice and Wild-Type Littermates. Frontiers in aging neuroscience. vol 9. 2021-01-09. PMID:28890695. |
alzheimer's disease (ad) is the most common neurodegenerative disease mainly caused by abnormal tau phosphorylation, amyloid β (aβ) deposition and neuroinflammation. |
2021-01-09 |
2023-08-13 |
mouse |
| Azadeh Firouzian, Alex Whittington, Graham E Searle, Ivan Koychev, Giovanna Zamboni, Simon Lovestone, Roger N Gun. Imaging Aβ and tau in early stage Alzheimer's disease with [ EJNMMI research. vol 8. issue 1. 2021-01-09. PMID:29500717. |
imaging aβ and tau in early stage alzheimer's disease with [ ad is a progressive neurodegenerative disorder that is associated with the accumulation of two different insoluble protein aggregates, aβ plaques and hyperphosphorylated tau. |
2021-01-09 |
2023-08-13 |
Not clear |
| Li Su, Yujing Huang, Yi Wang, James Rowe, John O'Brie. Predict Disease Progression With Reaction Rate Equation Modeling of Multimodal MRI and PET. Frontiers in aging neuroscience. vol 10. 2021-01-09. PMID:30349473. |
neurodegenerative dementia often has multiple types of underlying pathology, for example, beta-amyloid, misfolded tau, chronic neuroinflammation and neurodegeneration may coexist in alzheimer's disease. |
2021-01-09 |
2023-08-13 |
Not clear |
| Heather Pekeles, Hamid Y Qureshi, Hemant K Paudel, Hyman M Schipper, Mervyn Gornistky, Howard Chertko. Development and validation of a salivary tau biomarker in Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands). vol 11. 2021-01-09. PMID:30623019. |
development and validation of a salivary tau biomarker in alzheimer's disease. |
2021-01-09 |
2023-08-13 |
Not clear |
| Heather Pekeles, Hamid Y Qureshi, Hemant K Paudel, Hyman M Schipper, Mervyn Gornistky, Howard Chertko. Development and validation of a salivary tau biomarker in Alzheimer's disease. Alzheimer's & dementia (Amsterdam, Netherlands). vol 11. 2021-01-09. PMID:30623019. |
total tau (t-tau) and phosphorylated tau (p-tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with alzheimer's disease (ad). |
2021-01-09 |
2023-08-13 |
Not clear |
| Michel Goedert, Benjamin Falcon, Wenjuan Zhang, Bernardino Ghetti, Sjors H W Schere. Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases. Cold Spring Harbor symposia on quantitative biology. vol 83. 2021-01-09. PMID:30886056. |
distinct conformers of assembled tau in alzheimer's and pick's diseases. |
2021-01-09 |
2023-08-13 |
human |
| Michel Goedert, Benjamin Falcon, Wenjuan Zhang, Bernardino Ghetti, Sjors H W Schere. Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases. Cold Spring Harbor symposia on quantitative biology. vol 83. 2021-01-09. PMID:30886056. |
paired helical and straight tau filaments of alzheimer's disease (ad) are ultrastructural polymorphs. |
2021-01-09 |
2023-08-13 |
human |
| Carlos Areche, Francisca Zapata, Mathias González, Esteban Díaz, Rubén Montecinos, Marcos Hernández, Francisco Melo, Alberto Cornej. Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine-Cysteine Interaction. ChemistryOpen. vol 8. issue 5. 2021-01-09. PMID:31065505. |
neurodegenerative disorders including alzheimer's disease and tauopathies involved tau protein that is found hyperphosphorylated |
2021-01-09 |
2023-08-13 |
Not clear |
| Yachen Shi, Lihua Gu, Qing Wang, Lijuan Gao, Jianli Zhu, Xiang Lu, Fangfang Zhou, Dan Zhu, Haisan Zhang, Chunming Xie, Zhijun Zhan. Platelet Amyloid-β Protein Precursor (AβPP) Ratio and Phosphorylated Tau as Promising Indicators for Early Alzheimer's Disease. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 75. issue 4. 2021-01-08. PMID:31336382. |
platelet amyloid-β protein precursor (aβpp) ratio and phosphorylated tau as promising indicators for early alzheimer's disease. |
2021-01-08 |
2023-08-13 |
human |
| Yachen Shi, Lihua Gu, Qing Wang, Lijuan Gao, Jianli Zhu, Xiang Lu, Fangfang Zhou, Dan Zhu, Haisan Zhang, Chunming Xie, Zhijun Zhan. Platelet Amyloid-β Protein Precursor (AβPP) Ratio and Phosphorylated Tau as Promising Indicators for Early Alzheimer's Disease. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 75. issue 4. 2021-01-08. PMID:31336382. |
to identify whether platelet amyloid-β protein precursor (aβpp) ratio, phosphorylated-tau (p-tau) 231, p-tau181, and serine 396 and 404 (ser396/404) phosphorylated tau are potential peripheral indicators for early alzheimer's disease (ad). |
2021-01-08 |
2023-08-13 |
human |
| Xin Wang, Lei Zhang, Hui Lu, Juan-Li Wu, Hua-Zheng Liang, Chong Liu, Qing-Qing Tao, Zhi-Ying Wu, Ke-Qing Zh. Primary age-related tauopathy in a Chinese cohort. Journal of Zhejiang University. Science. B. vol 21. issue 3. 2021-01-07. PMID:32133802. |
primary age-related tauopathy (part) is characterized by the presence of tau neurofibrillary tangles (nfts) which are typically observed in alzheimer's disease (ad) brains, with few or without β-amyloid (aβ) plaques. |
2021-01-07 |
2023-08-13 |
human |
| Xiaofeng Xing, Chengqiang Liu, Aqsa Ali, Baotao Kang, Ping Li, Hongqi A. Novel Disassembly Mechanisms of Sigmoid Aβ ACS chemical neuroscience. vol 11. issue 1. 2021-01-06. PMID:31697060. |
novel disassembly mechanisms of sigmoid aβ alzheimer's disease (ad) is characterized by fibrillar deposits of amyloid-β (aβ) peptides and neurofibrillary tangles of tau proteins. |
2021-01-06 |
2023-08-13 |
Not clear |
| Thomas Vogels, Antoine Leuzy, Claudia Cicognola, Nicholas J Ashton, Tomas Smolek, Michal Novak, Kaj Blennow, Henrik Zetterberg, Tomas Hromadka, Norbert Zilka, Michael Schöl. Propagation of Tau Pathology: Integrating Insights From Postmortem and In Vivo Studies. Biological psychiatry. vol 87. issue 9. 2021-01-06. PMID:31735253. |
cellular accumulation of aggregated forms of the protein tau is a defining feature of so-called tauopathies such as alzheimer's disease, progressive supranuclear palsy, and chronic traumatic encephalopathy. |
2021-01-06 |
2023-08-13 |
human |
| Smita Eknath Desale, Subashchandrabose Chinnathamb. Role of dietary fatty acids in microglial polarization in Alzheimer's disease. Journal of neuroinflammation. vol 17. issue 1. 2021-01-06. PMID:32209097. |
in alzheimer's disease, one of the pathological proteins involved is tau protein, and microtubule-associated protein upon abnormal phosphorylation detaches from the microtubule and forms insoluble aggregates. |
2021-01-06 |
2023-08-13 |
Not clear |
| Smita Eknath Desale, Subashchandrabose Chinnathamb. Role of dietary fatty acids in microglial polarization in Alzheimer's disease. Journal of neuroinflammation. vol 17. issue 1. 2021-01-06. PMID:32209097. |
we hypothesize that tuning microglia towards anti-inflammatory phenotype would reduce the propagation of tau in alzheimer's disease. |
2021-01-06 |
2023-08-13 |
Not clear |
| Sun Ah Park, Jin Myung Jung, Jun Sung Park, Jeong Ho Lee, Bumhee Park, Hyung Jun Kim, Jeong-Ho Park, Won Seok Chae, Jee Hyang Jeong, Seong Hye Choi, Je-Hyun Bae. SWATH-MS analysis of cerebrospinal fluid to generate a robust battery of biomarkers for Alzheimer's disease. Scientific reports. vol 10. issue 1. 2021-01-06. PMID:32366888. |
cerebrospinal fluid (csf) aβ42 and tau protein levels are established diagnostic biomarkers of alzheimer's disease (ad). |
2021-01-06 |
2023-08-13 |
Not clear |
| Taeho Jo, Kwangsik Nho, Shannon L Risacher, Andrew J Sayki. Deep learning detection of informative features in tau PET for Alzheimer's disease classification. BMC bioinformatics. vol 21. issue Suppl 21. 2021-01-06. PMID:33371874. |
deep learning detection of informative features in tau pet for alzheimer's disease classification. |
2021-01-06 |
2023-08-13 |
Not clear |
| Azhaar A Ashraf, Melanie Dani, Po-Wah S. Low Cerebrospinal Fluid Levels of Hemopexin Are Associated With Increased Alzheimer's Pathology, Hippocampal Hypometabolism, and Cognitive Decline. Frontiers in molecular biosciences. vol 7. 2021-01-06. PMID:33392254. |
the aim of the present study was to examine the association of cerebrospinal fluid levels (csf) hemopexin and hemoglobin subunits (α and β) to alzheimer's pathological proteins (amyloid and tau), hippocampal volume and metabolism, and cognitive performance. |
2021-01-06 |
2023-08-13 |
human |