| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Skirmantas Janušoni. Serotonin dynamics in and around the central nervous system: is autism solvable without fundamental insights? International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 39. 2015-06-05. PMID:24886833. |
altered serotonin (5-hydroxytryptamine, 5-ht) signaling has been implicated in some developmental abnormalities of autism spectrum disorder (asd). |
2015-06-05 |
2023-08-13 |
Not clear |
| Nagwa A Meguid, Ola H Gebril, Rehab O Khali. A study of blood serotonin and serotonin transporter promoter variant (5-HTTLPR) polymorphism in Egyptian autistic children. Advanced biomedical research. vol 4. 2015-05-27. PMID:26015920. |
most studies have reported an elevation in platelet serotonin in persons with autism. |
2015-05-27 |
2023-08-13 |
Not clear |
| Mariano Soiza-Reilly, Kathryn G Common. Unraveling the architecture of the dorsal raphe synaptic neuropil using high-resolution neuroanatomy. Frontiers in neural circuits. vol 8. 2015-05-15. PMID:25206323. |
the dorsal raphe nucleus (drn), representing the main source of brain's serotonin, is implicated in the pathophysiology and therapeutics of several mental disorders that can be debilitating and life-long including depression, anxiety and autism. |
2015-05-15 |
2023-08-13 |
Not clear |
| Ryan M Smith, Wesley Banks, Emily Hansen, Wolfgang Sadee, Gail E Herma. Family-based clinical associations and functional characterization of the serotonin 2A receptor gene (HTR2A) in autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. vol 7. issue 4. 2015-05-14. PMID:24753316. |
family-based clinical associations and functional characterization of the serotonin 2a receptor gene (htr2a) in autism spectrum disorder. |
2015-05-14 |
2023-08-13 |
Not clear |
| Dea Adamsen, Vincent Ramaekers, Horace Tb Ho, Corinne Britschgi, Véronique Rüfenacht, David Meili, Elise Bobrowski, Paule Philippe, Caroline Nava, Lionel Van Maldergem, Rémy Bruggmann, Susanne Walitza, Joanne Wang, Edna Grünblatt, Beat Thön. Autism spectrum disorder associated with low serotonin in CSF and mutations in the SLC29A4 plasma membrane monoamine transporter (PMAT) gene. Molecular autism. vol 5. 2015-03-24. PMID:25802735. |
autism spectrum disorder associated with low serotonin in csf and mutations in the slc29a4 plasma membrane monoamine transporter (pmat) gene. |
2015-03-24 |
2023-08-13 |
Not clear |
| Dea Adamsen, Vincent Ramaekers, Horace Tb Ho, Corinne Britschgi, Véronique Rüfenacht, David Meili, Elise Bobrowski, Paule Philippe, Caroline Nava, Lionel Van Maldergem, Rémy Bruggmann, Susanne Walitza, Joanne Wang, Edna Grünblatt, Beat Thön. Autism spectrum disorder associated with low serotonin in CSF and mutations in the SLC29A4 plasma membrane monoamine transporter (PMAT) gene. Molecular autism. vol 5. 2015-03-24. PMID:25802735. |
patients with autism spectrum disorder (asd) may have low brain serotonin concentrations as reflected by the serotonin end-metabolite 5-hydroxyindolacetic acid (5hiaa) in cerebrospinal fluid (csf). |
2015-03-24 |
2023-08-13 |
Not clear |
| S E Sparks, C A Wassif, H Goodwin, S K Conley, D C Lanham, L E Kratz, K Hyland, A Gropman, E Tierney, F D Porte. Decreased cerebral spinal fluid neurotransmitter levels in Smith-Lemli-Opitz syndrome. Journal of inherited metabolic disease. vol 37. issue 3. 2015-02-20. PMID:24500076. |
in view of prior data suggesting defects in slos in vesicular release and given the association of altered serotonin metabolism with autism, we were interested in measuring neurotransmitter metabolite levels in slos to assess their potential to be used as biomarkers in therapeutic trials. |
2015-02-20 |
2023-08-12 |
human |
| Anissa Mouti, Dinah Reddihough, Catherine Marraffa, Philip Hazell, John Wray, Katherine Lee, Michael Koh. Fluoxetine for Autistic Behaviors (FAB trial): study protocol for a randomized controlled trial in children and adolescents with autism. Trials. vol 15. 2015-02-04. PMID:24934401. |
serotonin reuptake inhibitors (ssris) are commonly prescribed off-label for children with autism. |
2015-02-04 |
2023-08-13 |
Not clear |
| Shih-Hsien Lin, Lan-Ting Lee, Yen Kuang Yan. Serotonin and mental disorders: a concise review on molecular neuroimaging evidence. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 12. issue 3. 2015-01-19. PMID:25598822. |
in this concise review, we focus on evidence of the links between serotonin and major depressive disorders, as well as other mood disorders, anxiety disorders, schizophrenia, addiction, attention deficit hyperactivity disorder (adhd), and autism. |
2015-01-19 |
2023-08-13 |
Not clear |
| Stefano Gabriele, Roberto Sacco, Antonio M Persic. Blood serotonin levels in autism spectrum disorder: a systematic review and meta-analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 6. 2014-12-16. PMID:24613076. |
blood serotonin levels in autism spectrum disorder: a systematic review and meta-analysis. |
2014-12-16 |
2023-08-12 |
Not clear |
| Stefano Gabriele, Roberto Sacco, Antonio M Persic. Blood serotonin levels in autism spectrum disorder: a systematic review and meta-analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 6. 2014-12-16. PMID:24613076. |
elevated blood serotonin (5-ht) levels were the first biomarker identified in autism research. |
2014-12-16 |
2023-08-12 |
Not clear |
| Deepak Verma, Barnali Chakraborti, Arijit Karmakar, Tirthankar Bandyopadhyay, Asem Surindro Singh, Swagata Sinha, Anindita Chatterjee, Saurabh Ghosh, Kochupurackal P Mohanakumar, Kanchan Mukhopadhyay, Usha Rajamm. Sexual dimorphic effect in the genetic association of monoamine oxidase A (MAOA) markers with autism spectrum disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24291416. |
serotonin as modulator of behavior and implication of serotonergic dysfunction in asd etiology corroborates that serotonergic system genes are potential candidates for autism susceptibility. |
2014-12-11 |
2023-08-12 |
human |
| C-J Yang, H-P Tan, Y-J D. The developmental disruptions of serotonin signaling may involved in autism during early brain development. Neuroscience. vol 267. 2014-12-09. PMID:24583042. |
the developmental disruptions of serotonin signaling may involved in autism during early brain development. |
2014-12-09 |
2023-08-12 |
Not clear |
| C-J Yang, H-P Tan, Y-J D. The developmental disruptions of serotonin signaling may involved in autism during early brain development. Neuroscience. vol 267. 2014-12-09. PMID:24583042. |
the increased serotonin causes a decrease of oxytocin in the paraventricular nucleus of the hypothalamus and an increase in calcitonin gene-related peptide (cgrp) in the central nucleus of the amygdale, which are associated with social interactions and vital in autism. |
2014-12-09 |
2023-08-12 |
Not clear |
| C-J Yang, H-P Tan, Y-J D. The developmental disruptions of serotonin signaling may involved in autism during early brain development. Neuroscience. vol 267. 2014-12-09. PMID:24583042. |
and the paucity of placenta-derived serotonin should have potential importance when the pathogenesis of autism is considered. |
2014-12-09 |
2023-08-12 |
Not clear |
| C-J Yang, H-P Tan, Y-J D. The developmental disruptions of serotonin signaling may involved in autism during early brain development. Neuroscience. vol 267. 2014-12-09. PMID:24583042. |
this review briefly summarized the developmental disruptions of serotonin signaling involved in the pathogenesis of autism during early development of the brain. |
2014-12-09 |
2023-08-12 |
Not clear |
| Thomas Del'Guidice, Francis Lemay, Morgane Lemasson, Jean Levasseur-Moreau, Stella Manta, Adeline Etievant, Guy Escoffier, François Y Doré, François S Roman, Jean-Martin Beaulie. Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 5. 2014-12-01. PMID:24196946. |
polymorphisms in the gene encoding the serotonin synthesis enzyme tph2 have been identified in mental illnesses, including bipolar disorder, major depression, autism, schizophrenia, and adhd. |
2014-12-01 |
2023-08-12 |
mouse |
| Johanna Nyffeler, Susanne Walitza, Elise Bobrowski, Ronnie Gundelfinger, Edna Grünblat. Association study in siblings and case-controls of serotonin- and oxytocin-related genes with high functioning autism. Journal of molecular psychiatry. vol 2. issue 1. 2014-11-21. PMID:25408912. |
the serotonergic and oxytocinergic systems are of interest in autism for several reasons: (i) both systems are implicated in social behavior, and abnormal levels of serotonin and oxytocin have been found in people with asd; (ii) treatment with selective serotonin reuptake inhibitors and oxytocin can yield improvements; and (iii) previous association studies have linked the serotonin transporter (sert; slc6a4), serotonin receptor 2a (htr2a), and oxytocin receptor (oxtr) genes with asd. |
2014-11-21 |
2023-08-13 |
Not clear |
| Eileen Daly, Christine Ecker, Brian Hallahan, Quinton Deeley, Michael Craig, Clodagh Murphy, Patrick Johnston, Debbie Spain, Nicola Gillan, Maria Gudbrandsen, Michael Brammer, Vincent Giampietro, Melissa Lamar, Lisa Page, Fiona Toal, Nicole Schmitz, Anthony Cleare, Dene Robertson, Katya Rubia, Declan G M Murph. Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion. Brain : a journal of neurology. vol 137. issue Pt 9. 2014-11-06. PMID:25070512. |
response inhibition and serotonin in autism: a functional mri study using acute tryptophan depletion. |
2014-11-06 |
2023-08-13 |
human |
| Eileen Daly, Christine Ecker, Brian Hallahan, Quinton Deeley, Michael Craig, Clodagh Murphy, Patrick Johnston, Debbie Spain, Nicola Gillan, Maria Gudbrandsen, Michael Brammer, Vincent Giampietro, Melissa Lamar, Lisa Page, Fiona Toal, Nicole Schmitz, Anthony Cleare, Dene Robertson, Katya Rubia, Declan G M Murph. Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion. Brain : a journal of neurology. vol 137. issue Pt 9. 2014-11-06. PMID:25070512. |
we therefore assessed the modifying role of serotonin on inhibitory brain function during a go/no-go task in 14 adults with autism and normal intelligence and 14 control subjects that did not differ in gender, age and intelligence. |
2014-11-06 |
2023-08-13 |
human |