| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca A Harrington, Li-Ching Lee, Rosa M Crum, Andrew W Zimmerman, Irva Hertz-Picciott. Serotonin hypothesis of autism: implications for selective serotonin reuptake inhibitor use during pregnancy. Autism research : official journal of the International Society for Autism Research. vol 6. issue 3. 2014-02-19. PMID:23495208. |
serotonin, a neurotransmitter found throughout the brain and body, has long been of interest in autism. |
2014-02-19 |
2023-08-12 |
Not clear |
| Rebecca A Harrington, Li-Ching Lee, Rosa M Crum, Andrew W Zimmerman, Irva Hertz-Picciott. Serotonin hypothesis of autism: implications for selective serotonin reuptake inhibitor use during pregnancy. Autism research : official journal of the International Society for Autism Research. vol 6. issue 3. 2014-02-19. PMID:23495208. |
repeated findings of elevated platelet serotonin levels in approximately one third of children with autism has led some to believe that dysfunctional serotonin signaling may be a causal mechanism for the disorder. |
2014-02-19 |
2023-08-12 |
Not clear |
| Masayuki Fujiwara, Hikaru Yamamoto, Tatsuhiro Miyagi, Takahiro Seki, Shigeru Tanaka, Izumi Hide, Norio Saka. Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells. Journal of pharmacological sciences. vol 122. issue 2. 2014-01-09. PMID:23676312. |
the serotonin transporter (sert) is involved in various psychiatric disorders, including depression and autism. |
2014-01-09 |
2023-08-12 |
Not clear |
| Anders Hviid, Mads Melbye, Björn Pasterna. Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism. The New England journal of medicine. vol 369. issue 25. 2013-12-24. PMID:24350950. |
use of selective serotonin reuptake inhibitors during pregnancy and risk of autism. |
2013-12-24 |
2023-08-12 |
Not clear |
| Gül Dölen, Ayeh Darvishzadeh, Kee Wui Huang, Robert C Malenk. Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin. Nature. vol 501. issue 7466. 2013-12-11. PMID:24025838. |
these results demonstrate that the rewarding properties of social interaction in mice require the coordinated activity of oxytocin and 5-ht in the nucleus accumbens, a mechanistic insight with implications for understanding the pathogenesis of social dysfunction in neuropsychiatric disorders such as autism. |
2013-12-11 |
2023-08-12 |
mouse |
| Nicholas G Campbell, Chong-Bin Zhu, Kathryn M Lindler, Brian L Yaspan, Emily Kistner-Griffin, William A Hewlett, Christopher G Tate, Randy D Blakely, James S Sutcliff. Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome. Molecular autism. vol 4. issue 1. 2013-11-15. PMID:23953133. |
rare coding variants of the adenosine a3 receptor are increased in autism: on the trail of the serotonin transporter regulome. |
2013-11-15 |
2023-08-12 |
Not clear |
| Travis M Kerr, Christopher L Muller, Mahfuzur Miah, Christopher S Jetter, Rita Pfeiffer, Charisma Shah, Nicole Baganz, George M Anderson, Jacqueline N Crawley, James S Sutcliffe, Randy D Blakely, Jeremy Veenstra-Vanderweel. Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice. Molecular autism. vol 4. issue 1. 2013-11-15. PMID:24083388. |
previously, we identified multiple, rare serotonin (5-ht) transporter (sert) variants in children with autism spectrum disorder (asd). |
2013-11-15 |
2023-08-12 |
mouse |
| Kohji Sat. Placenta-derived hypo-serotonin situations in the developing forebrain cause autism. Medical hypotheses. vol 80. issue 4. 2013-09-11. PMID:23375670. |
since all these events have been considered to be involved in the pathogenesis of autism and they are highly controlled by serotonin signals, the paucity of placenta-derived serotonin should have potential importance when the pathogenesis of autism is considered. |
2013-09-11 |
2023-08-12 |
mouse |
| Leila Hassanzadeh, Mostafa Erfani, Reza Najafi, Mohammad Shafiei, Mohsen Amini, Abbass Shafiee, Seyed Esmaeil Sadat Ebrahim. Synthesis, radiolabeling and bioevaluation of a novel arylpiperazine derivative containing triazole as a 5-HT1A receptor imaging agents. Nuclear medicine and biology. vol 40. issue 2. 2013-07-25. PMID:23141548. |
it has been recognized that serotonin plays a main role in various pathological conditions such as anxiety, depression, aggressiveness, schizophrenia, suicidal behavior, panic and autism. |
2013-07-25 |
2023-08-12 |
Not clear |
| Bryan K Sander. Flowers for Algernon: steroid dysgenesis, epigenetics and brain disorders. Pharmacological reports : PR. vol 64. issue 6. 2013-07-16. PMID:23406739. |
while a recent study has reported that early citalopram exposure alters cortical network function and produces autistic-like behaviors in male rats, when evaluating antidepressant animal models of autism spectrum disorder (asd) it is important to note that some selective serotonin (5-ht) reuptake inhibitors alter 3α-hydroxysteroid dehydrogenase activity, and thus steroidogenesis. |
2013-07-16 |
2023-08-12 |
mouse |
| Nicole L Baganz, Randy D Blakel. A dialogue between the immune system and brain, spoken in the language of serotonin. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336044. |
from this perspective, altered 5-ht/immune conversations are likely to contribute to risk for neurobehavioral disorders historically linked to compromised 5-ht function or ameliorated by 5-ht targeted medications, including depression and anxiety disorders, obsessive-compulsive disorder (ocd), and autism. |
2013-07-02 |
2023-08-12 |
Not clear |
| Karsten Kinast, Deborah Peeters, Sharon M Kolk, Dirk Schubert, Judith R Homber. Genetic and pharmacological manipulations of the serotonergic system in early life: neurodevelopmental underpinnings of autism-related behavior. Frontiers in cellular neuroscience. vol 7. 2013-06-20. PMID:23781172. |
serotonin, in its function as neurotransmitter, is well-known for its role in depression, autism and other neuropsychiatric disorders, however, less known as a neurodevelopmental factor. |
2013-06-20 |
2023-08-12 |
human |
| Michael J Kane, Mariana Angoa-Peréz, Denise I Briggs, Catherine E Sykes, Dina M Francescutti, David R Rosenberg, Donald M Kuh. Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism. PloS one. vol 7. issue 11. 2013-04-23. PMID:23139830. |
mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism. |
2013-04-23 |
2023-08-12 |
mouse |
| Michael J Kane, Mariana Angoa-Peréz, Denise I Briggs, Catherine E Sykes, Dina M Francescutti, David R Rosenberg, Donald M Kuh. Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism. PloS one. vol 7. issue 11. 2013-04-23. PMID:23139830. |
one factor known to exert extremely broad influence on brain development and network formation, and which has been linked to autism, is the neurotransmitter serotonin. |
2013-04-23 |
2023-08-12 |
mouse |
| Michael J Kane, Mariana Angoa-Peréz, Denise I Briggs, Catherine E Sykes, Dina M Francescutti, David R Rosenberg, Donald M Kuh. Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism. PloS one. vol 7. issue 11. 2013-04-23. PMID:23139830. |
unfortunately, very little is known about how alterations in serotonin neuronal function might contribute to autism. |
2013-04-23 |
2023-08-12 |
mouse |
| Michael J Kane, Mariana Angoa-Peréz, Denise I Briggs, Catherine E Sykes, Dina M Francescutti, David R Rosenberg, Donald M Kuh. Mice genetically depleted of brain serotonin display social impairments, communication deficits and repetitive behaviors: possible relevance to autism. PloS one. vol 7. issue 11. 2013-04-23. PMID:23139830. |
to test the hypothesis that serotonin dysfunction can contribute to the core symptoms of autism, we analyzed mice lacking brain serotonin (via a null mutation in the gene for tryptophan hydroxylase 2 (tph2)) for behaviors that are relevant to this disorder. |
2013-04-23 |
2023-08-12 |
mouse |
| Shi-Sheng Zhou, Yi-Ming Zhou, Da Li, Qiang M. Early infant exposure to excess multivitamin: a risk factor for autism? Autism research and treatment. vol 2013. 2013-03-28. PMID:23533752. |
autism, a neurodevelopmental disorder that affects boys more than girls, is often associated with altered levels of monoamines (serotonin and catecholamines), especially elevated serotonin levels. |
2013-03-28 |
2023-08-12 |
Not clear |
| Kenneth D Gadow, Carla J DeVincent, Victoria I Siegal, Doreen M Olvet, Saniya Kibria, Sarah F Kirsch, Eli Hatchwel. Allele-specific associations of 5-HTTLPR/rs25531 with ADHD and autism spectrum disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:23123360. |
the aims of the present study were to examine the association between a common serotonin transporter gene (slc6a4) polymorphism 5-httlpr/rs25531 with severity of attention-deficit hyperactivity disorder (adhd) and autism spectrum disorder (asd) symptoms. |
2013-03-26 |
2023-08-12 |
Not clear |
| M Febin Farook, Michael DeCuypere, Keith Hyland, Toru Takumi, Mark S LeDoux, Lawrence T Reite. Altered serotonin, dopamine and norepinepherine levels in 15q duplication and Angelman syndrome mouse models. PloS one. vol 7. issue 8. 2013-01-16. PMID:22916201. |
we found that serotonin (5ht), a monoamine affected in autism, was elevated in the striatum and cortex of as mice. |
2013-01-16 |
2023-08-12 |
mouse |
| M Febin Farook, Michael DeCuypere, Keith Hyland, Toru Takumi, Mark S LeDoux, Lawrence T Reite. Altered serotonin, dopamine and norepinepherine levels in 15q duplication and Angelman syndrome mouse models. PloS one. vol 7. issue 8. 2013-01-16. PMID:22916201. |
in the duplication 15q autism mouse model, paternal but not maternal duplication animals showed a decrease in 5ht levels when compared to their wild type littermates, in accordance with previously published data. |
2013-01-16 |
2023-08-12 |
mouse |