Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Gian Lucas M Arruda, Hugo Vigerelli, Michelle C Bufalo, Giovanna B Longato, Rodinei V Veloso, Vanessa O Zambelli, Gisele Picolo, Yara Cury, André C Morandini, Antonio Carlos Marques, Juliana Mozer Scian. Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect. BioMed research international. vol 2021. 2021-05-25. PMID:33748281. |
neurodegenerative diseases are one of the major causes of death worldwide, characterized by neurite atrophy, neuron apoptosis, and synapse loss. |
2021-05-25 |
2023-08-13 |
Not clear |
Muhammad Safdar, Sana Zaheer, Rozhgar A Khailany, Sadaf Parvez, Muhammad Naveed, Piplu Bhuiyan, Mehmet Ozaslan, Rebaz Moatasam, Mustafa S Al-Attar, Musarrat Abbas Khan, Yasmeen Junej. The Relevance of SNPs at 3'UTR Region of CASP7 and miR-371b-5p Associated Diseases: A Computational Analysis. Cell biochemistry and biophysics. vol 78. issue 4. 2021-05-19. PMID:32951155. |
disruption of apoptosis may lead to aberrant immune responses, cancer, and neurodegenerative diseases. |
2021-05-19 |
2023-08-13 |
human |
Chenxing Fu, Jie Zhan, Junqi Huai, Shaodan Ma, Minghui Li, Guoqin Chen, Minsheng Chen, Yanbin Cai, Caiwen O. Furin-instructed molecular self-assembly actuates endoplasmic reticulum stress-mediated apoptosis for cancer therapy. Nanoscale. vol 12. issue 22. 2021-05-14. PMID:32484200. |
severe er stress-mediated apoptosis is the cause of neurodegenerative diseases and expected to be a new target for cancer therapy. |
2021-05-14 |
2023-08-13 |
Not clear |
Cheng-Cheng Wang, Hao-Hao Shi, Jie Xu, Teruyoshi Yanagita, Chang-Hu Xue, Tian-Tian Zhang, Yu-Ming Wan. Docosahexaenoic acid-acylated astaxanthin ester exhibits superior performance over non-esterified astaxanthin in preventing behavioral deficits coupled with apoptosis in MPTP-induced mice with Parkinson's disease. Food & function. vol 11. issue 9. 2021-05-06. PMID:32845953. |
dha-ast was superior to ast in preventing behavioral deficits coupled with apoptosis rather than oxidative stress, and might provide a valuable reference for the prevention and treatment of neurodegenerative diseases. |
2021-05-06 |
2023-08-13 |
mouse |
Saray Tabak, Sofia Schreiber-Avissar, Elie Beit-Yanna. Crosstalk between MicroRNA and Oxidative Stress in Primary Open-Angle Glaucoma. International journal of molecular sciences. vol 22. issue 5. 2021-04-30. PMID:33670885. |
reactive oxygen species (ros) plays a key role in the pathogenesis of primary open-angle glaucoma (poag), a chronic neurodegenerative disease that damages the trabecular meshwork (tm) cells, inducing apoptosis of the retinal ganglion cells (rgc), deteriorating the optic nerve head, and leading to blindness. |
2021-04-30 |
2023-08-13 |
Not clear |
Liya Qin, Jian Zou, Alexandra Barnett, Ryan P Vetreno, Fulton T Crews, Leon G Colema. TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration. International journal of molecular sciences. vol 22. issue 5. 2021-04-26. PMID:33806288. |
tlr7 and neuronal apoptosis are implicated in other neurodegenerative diseases, including alzheimer's disease. |
2021-04-26 |
2023-08-13 |
mouse |
Paweł Łukasik, Michał Załuski, Izabela Gutowsk. Cyclin-Dependent Kinases (CDK) and Their Role in Diseases Development-Review. International journal of molecular sciences. vol 22. issue 6. 2021-04-23. PMID:33805800. |
deregulation of any of the stages of the cell cycle or transcription leads to apoptosis but, if uncorrected, can result in a series of diseases, such as cancer, neurodegenerative diseases (alzheimer's or parkinson's disease), and stroke. |
2021-04-23 |
2023-08-13 |
Not clear |
b' Katarina \\xc5\\xbdivan\\xc4\\x8devi\\xc4\\x87, Katarina Barali\\xc4\\x87, Dragica Jorgovanovi\\xc4\\x87, Aleksandra Buha Djordjevi\\xc4\\x87, Marijana \\xc4\\x86ur\\xc4\\x8di\\xc4\\x87, Evica Antonijevi\\xc4\\x87 Miljakovi\\xc4\\x87, Biljana Antonijevi\\xc4\\x87, Zorica Bulat, Danijela \\xc4\\x90uki\\xc4\\x87-\\xc4\\x86osi\\xc4\\x8. Elucidating the influence of environmentally relevant toxic metal mixture on molecular mechanisms involved in the development of neurodegenerative diseases: In silico toxicogenomic data-mining. Environmental research. vol 194. 2021-04-21. PMID:33465344.' |
oxidative stress, folate metabolism, vitamin b12, age-rage, apoptosis were noted as the key disrupted molecular pathways that contribute to the neurodegenerative disease's development. |
2021-04-21 |
2023-08-13 |
Not clear |
Mariano Catanesi, Michele d'Angelo, Maria Grazia Tupone, Elisabetta Benedetti, Antonio Giordano, Vanessa Castelli, Annamaria Cimin. MicroRNAs Dysregulation and Mitochondrial Dysfunction in Neurodegenerative Diseases. International journal of molecular sciences. vol 21. issue 17. 2021-04-13. PMID:32825273. |
moreover, mirnas are crucial for different processes, including cell growth, signal transmission, apoptosis, cancer and aging-related neurodegenerative diseases. |
2021-04-13 |
2023-08-13 |
Not clear |
Ge Yang, Pin Wan, Qi Xiang, Shanyu Huang, Siyu Huang, Jun Wang, Kailang Wu, Jianguo W. E3 Ubiquitin Ligase ASB17 Promotes Apoptosis by Ubiquitylating and Degrading BCLW and MCL1. Biology. vol 10. issue 3. 2021-04-13. PMID:33803505. |
altered apoptosis results in a disorder of cell death and is associated with many diseases such as neurodegenerative diseases and cancers. |
2021-04-13 |
2023-08-13 |
mouse |
Mutsumi Yokota, Soichiro Kakuta, Takahiro Shiga, Kei-Ichi Ishikawa, Hideyuki Okano, Nobutaka Hattori, Wado Akamatsu, Masato Koik. Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons. Molecular brain. vol 14. issue 1. 2021-04-09. PMID:33757554. |
mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. |
2021-04-09 |
2023-08-13 |
Not clear |
Abbas Mohammadipour, Hossein Haghir, Alireza Ebrahimzadeh Bideska. A link between nanoparticles and Parkinson's disease. Which nanoparticles are most harmful? Reviews on environmental health. vol 35. issue 4. 2021-03-30. PMID:32681785. |
pd is the second most common neurodegenerative disease in the world, and in patients, its symptoms progressively worsen day by day through different pathways including oxidative stress, neuroinflammation, mitochondrial dysfunction, α-synuclein increasing and aggregation, apoptosis and reduction of tyrosine hydroxylase positive cells. |
2021-03-30 |
2023-08-13 |
Not clear |
Nady Braidy, Tarik Smani, Mustafa Nazirogl. Editorial: Involvements of TRP Channels, Oxidative Stress and Apoptosis in Neurodegenerative Diseases. Frontiers in physiology. vol 12. 2021-03-29. PMID:33776800. |
editorial: involvements of trp channels, oxidative stress and apoptosis in neurodegenerative diseases. |
2021-03-29 |
2023-08-13 |
Not clear |
Panpan Yao, Liping Zhou, Lujie Zhu, Binjie Zhou, Qin Y. Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Neurodegenerative Diseases. European neurology. vol 83. issue 3. 2021-03-18. PMID:32690856. |
neurodegenerative disease is a kind of chronic, progressive nervous system disease characterized by neuron degeneration or apoptosis. |
2021-03-18 |
2023-08-13 |
Not clear |
Shang-Der Chen, Jenq-Lin Yang, Yi-Chun Lin, A-Ching Chao, Ding-I Yan. Emerging Roles of Inhibitor of Differentiation-1 in Alzheimer's Disease: Cell Cycle Reentry and Beyond. Cells. vol 9. issue 7. 2021-03-05. PMID:32708313. |
a thorough understanding of the underlying mechanisms may provide a rationale to make an earlier intervention before the occurrence of cell cycle reentry and subsequent apoptosis in the fully differentiated neurons during the progression of ad or other neurodegenerative diseases. |
2021-03-05 |
2023-08-13 |
Not clear |
Junqiang Yan, Hongxia Ma, Xiaoyi Lai, Jiannan Wu, Anran Liu, Jiarui Huang, Wenjie Sun, Mengmeng Shen, Yude Zhan. Artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in MPP Journal of biological research (Thessalonike, Greece). vol 28. issue 1. 2021-02-28. PMID:33632304. |
artemisinin attenuated oxidative stress and apoptosis by inhibiting autophagy in mpp parkinson's disease (pd) is the second most common neurodegenerative disease after alzheimer's disease. |
2021-02-28 |
2023-08-13 |
Not clear |
Dalia M Kopustinskiene, Jurga Bernatonien. Molecular Mechanisms of Melatonin-Mediated Cell Protection and Signaling in Health and Disease. Pharmaceutics. vol 13. issue 2. 2021-02-27. PMID:33498316. |
melatonin protects from oxidative stress in ischemic/reperfusion injury, neurodegenerative diseases, and aging, decreases inflammation, modulates the immune system, inhibits proliferation, counteracts the warburg effect, and promotes apoptosis in various cancer models. |
2021-02-27 |
2023-08-13 |
Not clear |
Jiayan Li, Xuhui Chen, Xuan Li, Rong Hu, Wenlong Yao, Wei Mei, Li Wan, Lingli Gui, Chuanhan Zhan. Upregulation of Cdh1 in the trigeminal spinal subnucleus caudalis attenuates trigeminal neuropathic pain via inhibiting GABAergic neuronal apoptosis. Neurochemistry international. vol 133. 2021-02-23. PMID:31785347. |
it has also demonstrated that downregulation of the anaphase-promoting complex/cyclosome(apc/c) and its coactivator cdh1 contribute to neuronal apoptosis in diverse neurodegenerative diseases. |
2021-02-23 |
2023-08-13 |
rat |
Mona Mosayebnia, Maliheh Hajiramezanali, Soraya Shahhossein. Radiolabeled Peptides for Molecular Imaging of Apoptosis. Current medicinal chemistry. vol 27. issue 41. 2021-02-02. PMID:32532184. |
tracking of apoptosis provides an opportunity for the assessment of cardiovascular and neurodegenerative diseases as well as monitoring of cancer therapy at early stages. |
2021-02-02 |
2023-08-13 |
Not clear |
Lucas A Luna, Zachary Lesecq, Katharine A White, An Hoang, David A Scott, Olga Zagnitko, Andrey A Bobkov, Diane L Barber, Jamie M Schiffer, Daniel G Isom, Christal D Soh. An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity. The Biochemical journal. vol 477. issue 16. 2021-02-01. PMID:32729927. |
this led us to question whether idh1 catalysis is ph-regulated, which would have functional implications under conditions that alter cellular ph, like apoptosis, hypoxia, cancer, and neurodegenerative diseases. |
2021-02-01 |
2023-08-13 |
Not clear |