| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yingfeng Tu, Xiaoling Li, Xuefei Zhu, Xiaokang Liu, Caixia Guo, Da Jia, Tie-Shan Tan. Determining the Fate of Neurons in SCA3: ATX3, a Rising Decision Maker in Response to DNA Stresses and Beyond. Frontiers in cell and developmental biology. vol 8. 2021-01-12. PMID:33425926. |
dna damage response (ddr) and apoptosis are reported to be involved in the pathogenesis of many neurodegenerative diseases including polyglutamine (polyq) disorders, such as spinocerebellar ataxia type 3 (sca3) and huntington's disease (hd). |
2021-01-12 |
2023-08-13 |
Not clear |
| Abu Hazafa, Ammara Batool, Saeed Ahmad, Muhammad Amjad, Sundas Nasir Chaudhry, Jamal Asad, Hasham Feroz Ghuman, Hafiza Madeeha Khan, Muhammad Naeem, Usman Ghan. Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseases. Life sciences. vol 264. 2020-12-31. PMID:33130077. |
based on in vitro and in vivo studies, hn significantly suppressed the apoptosis during the treatment of bone osteoporosis, cardiovascular diseases, diabetes mellitus, and neurodegenerative diseases. |
2020-12-31 |
2023-08-13 |
human |
| Yan-Xia Hao, Mei-Qin Li, Jing-Si Zhang, Qin-Li Zhang, Xia Jiao, Xiu-Liang Ji, Huan Li, Qiao Ni. Aluminum-induced "mixed" cell death in mice cerebral tissue and potential intervention. Neurotoxicity research. vol 37. issue 4. 2020-12-21. PMID:31721047. |
our study evidenced al-induced neuronal necroptosis and apoptosis existing in animal model and suggested potential therapeutic effects of nec-1 and z-vad-fmk on neuronal cell death in neurodegenerative diseases. |
2020-12-21 |
2023-08-13 |
mouse |
| Damilare D Akintade, Bhabatosh Chaudhur. The effect of copy number on α-synuclein's toxicity and its protective role in Bax-induced apoptosis, in yeast. Bioscience reports. vol 40. issue 9. 2020-12-08. PMID:32794578. |
bax and α-synuclein are two human proteins which play a role in the induction of neuronal apoptosis in neurodegenerative diseases like alzheimer's and parkinson's. |
2020-12-08 |
2023-08-13 |
human |
| Yiming Deng, Jingyu Zhang, Xuan Sun, Gaoting Ma, Gang Luo, Zhongrong Miao, Ligang Son. miR-132 improves the cognitive function of rats with Alzheimer's disease by inhibiting the MAPK1 signal pathway. Experimental and therapeutic medicine. vol 20. issue 6. 2020-10-24. PMID:33093897. |
the dysregulation of mirna is crucial in neurodegenerative diseases and neuron apoptosis during ad and is closely associated with the mapk pathway. |
2020-10-24 |
2023-08-13 |
mouse |
| Satoru Tada, Tatsusada Okuno, Mikito Shimizu, Yoshiki Sakai, Hisae Sumi-Akamaru, Makoto Kinoshita, Kazuya Yamashita, Eri Sanda, Chi-Jing Choong, Akiko Namba, Tsutomu Sasaki, Toru Koda, Kazushiro Takata, Shigeru Miyagawa, Yoshiki Sawa, Yuji Nakatsuji, Hideki Mochizuk. Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis. Scientific reports. vol 9. issue 1. 2020-10-05. PMID:30918303. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by several pathologies including oxidative stress, apoptosis, neuroinflammation, and glutamate toxicity. |
2020-10-05 |
2023-08-13 |
mouse |
| Aric Flint Logsdon, Brandon Peter Lucke-Wold, Charles Lee Rosen, Jason Delwyn Hube. Disparity among neural injury models and the unfolded protein response. Journal of neurological disorders & stroke. vol 2. issue 3. 2020-10-01. PMID:27284579. |
evidence suggests that targeting the right transcription factors, at the right time, will aid in the prevention of apoptosis and neurodegenerative disease development following neural injury. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mahsa Eghlidospour, Amir Ghanbari, Seyyed Mohammad Javad Mortazavi, Hassan Azar. Effects of radiofrequency exposure emitted from a GSM mobile phone on proliferation, differentiation, and apoptosis of neural stem cells. Anatomy & cell biology. vol 50. issue 2. 2020-10-01. PMID:28713615. |
due to the importance of neural stem cells (nscs) in plasticity of the nervous system and treating neurodegenerative diseases, the main goal of this study was to evaluate the effects of radiofrequency radiation emitted from a gsm 900-mhz mobile phone with different exposure duration on proliferation, differentiation and apoptosis of adult murine nscs |
2020-10-01 |
2023-08-13 |
Not clear |
| Olena Y Glushakova, Andriy A Glushakov, Dayanjan S Wijesinghe, Alex B Valadka, Ronald L Hayes, Alexander V Glushako. Prospective clinical biomarkers of caspase-mediated apoptosis associated with neuronal and neurovascular damage following stroke and other severe brain injuries: Implications for chronic neurodegeneration. Brain circulation. vol 3. issue 2. 2020-10-01. PMID:30276309. |
apoptosis involving caspase-3 is one of the most common mechanisms involved in the etiopathology of both acute and chronic neurological and neurodegenerative diseases, suggesting a relationship between these disorders. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jens Stepan, Elmira Anderzhanova, Nils C Gasse. Hippo Signaling: Emerging Pathway in Stress-Related Psychiatric Disorders? Frontiers in psychiatry. vol 9. 2020-10-01. PMID:30627107. |
upon diverse extracellular and intracellular stimuli, hippo signaling regulates stemness, cell proliferation and apoptosis by a well-conserved signaling cascade, and disruption of these systems has been implicated in cancer as well as metabolic and neurodegenerative diseases. |
2020-10-01 |
2023-08-13 |
Not clear |
| Md Jakaria, Shofiul Azam, Duk-Yeon Cho, Md Ezazul Haque, In-Su Kim, Dong-Kug Cho. The Methanol Extract of Antioxidants (Basel, Switzerland). vol 8. issue 9. 2020-10-01. PMID:31480531. |
the methanol extract of neuroinflammation, apoptosis, and oxidative stress are connected to the pathogenesis of neurodegenerative diseases (ndds). |
2020-10-01 |
2023-08-13 |
Not clear |
| Mingda Wang, Hongming Sun, Yina Yao, Xicun Tang, Bo W. MicroRNA-217/138-5p downregulation inhibits inflammatory response, oxidative stress and the induction of neuronal apoptosis in MPP American journal of translational research. vol 11. issue 10. 2020-10-01. PMID:31737212. |
microrna-217/138-5p downregulation inhibits inflammatory response, oxidative stress and the induction of neuronal apoptosis in mpp parkinson's disease (pd) is a common neurodegenerative disease. |
2020-10-01 |
2023-08-13 |
Not clear |
| Gwyn T Williams, Jane P Hughes, Victoria Stoneman, Claire L Anderson, Nicola J McCarthy, Mirna Mourtada-Maarabouni, Mark Pickard, Vanessa L Hedge, Ian Trayner, Farzin Farzane. Isolation of genes controlling apoptosis through their effects on cell survival. Gene therapy & molecular biology. vol 10. issue B. 2020-09-30. PMID:17372619. |
we have applied forward genetics approaches to the identification of the critical genes involved in the control of apoptosis in mammalian cells, since defective control of apoptosis underlies many diseases, including cancer and neurodegenerative diseases. |
2020-09-30 |
2023-08-12 |
Not clear |
| Zili He, Yulong Zhou, Yan Huang, Qingqing Wang, Binbin Zheng, Hongyu Zhang, Jiawei Li, Yanlong Liu, Fenzan Wu, Xie Zhang, Songlin Tong, Maofeng Wang, Zhouguang Wang, Huacheng He, Huazi Xu, Jian Xia. Dl-3-n-butylphthalide improves functional recovery in rats with spinal cord injury by inhibiting endoplasmic reticulum stress-induced apoptosis. American journal of translational research. vol 9. issue 3. 2020-09-30. PMID:28386335. |
dl-3-n-butylphthalide (nbp) exerts an neuroprotective effects against both ischemic brain injury and neurodegenerative diseases; however, the relationship between er stress-induced apoptosis and the therapeutic effect of nbp in sci remains unclear. |
2020-09-30 |
2023-08-13 |
rat |
| Larissa Takser, Nora Benachour, Barry Husk, Hubert Cabana, Denis Gri. Cyanotoxins at low doses induce apoptosis and inflammatory effects in murine brain cells: Potential implications for neurodegenerative diseases. Toxicology reports. vol 3. 2020-09-30. PMID:28959538. |
cyanotoxins at low doses induce apoptosis and inflammatory effects in murine brain cells: potential implications for neurodegenerative diseases. |
2020-09-30 |
2023-08-13 |
Not clear |
| Giorgia Manzo, Ilaria Serra, Andrea Magrí, Mariano Casu, Vito De Pinto, Matteo Ceccarelli, Mariano Andrea Scorciapin. Folded Structure and Membrane Affinity of the N-Terminal Domain of the Three Human Isoforms of the Mitochondrial Voltage-Dependent Anion-Selective Channel. ACS omega. vol 3. issue 9. 2020-09-30. PMID:30320261. |
in particular, their role in energy-related nucleotide exchange has many implications in apoptosis, cancer, and neurodegenerative diseases. |
2020-09-30 |
2023-08-13 |
human |
| Kyoungjoo Ch. Emerging Roles of Complement Protein C1q in Neurodegeneration. Aging and disease. vol 10. issue 3. 2020-09-30. PMID:31165008. |
because c1q participates in the clearance of pathogens, its interaction with novel receptors is expected to facilitate apoptosis induction, which could prevent the onset or progression of neurodegenerative diseases and could delay the aging process. |
2020-09-30 |
2023-08-13 |
Not clear |
| Muhammad Ayaz, Abdul Sadiq, Muhammad Junaid, Farhat Ullah, Muhammad Ovais, Ikram Ullah, Jawad Ahmed, Muhammad Shahi. Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders. Frontiers in aging neuroscience. vol 11. 2020-09-30. PMID:31293414. |
flavonoids also hamper the progression of pathological symptoms of neurodegenerative diseases by inhibiting neuronal apoptosis induced by neurotoxic substances including free radicals and β-amyloid proteins (aβ). |
2020-09-30 |
2023-08-13 |
Not clear |
| Quan Li, Bai-Ling Wang, Fu-Rong Sun, Jie-Qiong Li, Xi-Peng Cao, Lan Ta. The role of Annals of translational medicine. vol 6. issue 10. 2020-09-29. PMID:29951500. |
the role of alzheimer's disease (ad) is a chronic progressive neurodegenerative disease in adults characterized by the deposition of extracellular plaques of β-amyloid protein (aβ), intracellular neurofibrillary tangles (nfts), synaptic loss and neuronal apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Huntington Potter, Heidi J Chial, Julbert Caneus, Mihret Elos, Nina Elder, Sergiy Borysov, Antoneta Grani. Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders. Frontiers in genetics. vol 10. 2020-09-28. PMID:31788001. |
evidence from multiple laboratories has accumulated to show that mosaic neuronal aneuploidy and consequent apoptosis characterizes and may underlie neuronal loss in many neurodegenerative diseases, particularly alzheimer's disease and frontotemporal dementia. |
2020-09-28 |
2023-08-13 |
Not clear |