| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Niehues, T W McCloskey, J Ndagijimana, G Horneff, V Wahn, S Pahw. Apoptosis in T-lymphocyte subsets in human immunodeficiency virus-infected children measured immediately ex vivo and following in vitro activation. Clinical and diagnostic laboratory immunology. vol 8. issue 1. 2001-03-22. PMID:11139198. |
these results demonstrate that in hiv-infected children, cd8 apoptosis may occur at a greater rate than cd4 apoptosis in vivo; greater cd4 depletion may be observed due to more efficient mechanisms for peripheral lymphocyte replacement in the cd8 compartment. |
2001-03-22 |
2023-08-12 |
human |
| P M Roger, J P Breittmayer, J Cottalorda, M Ticchioni, V Mondain, P Dellamonica, A Bernar. Persistent viral load in patients on HAART is associated with a higher level of activation-induced apoptosis of CD4(+) T cells. The Journal of antimicrobial chemotherapy. vol 47. issue 1. 2001-03-22. PMID:11152441. |
persistent viral load in patients on haart is associated with a higher level of activation-induced apoptosis of cd4(+) t cells. |
2001-03-22 |
2023-08-12 |
human |
| P M Roger, J P Breittmayer, J Cottalorda, M Ticchioni, V Mondain, P Dellamonica, A Bernar. Persistent viral load in patients on HAART is associated with a higher level of activation-induced apoptosis of CD4(+) T cells. The Journal of antimicrobial chemotherapy. vol 47. issue 1. 2001-03-22. PMID:11152441. |
apoptosis is one of the mechanisms involved in the persistent cd4(+) t cell lymphopenia occurring in human immunodeficiency virus (hiv)-infected patients treated with highly active antiretroviral therapy (haart). |
2001-03-22 |
2023-08-12 |
human |
| P M Roger, J P Breittmayer, J Cottalorda, M Ticchioni, V Mondain, P Dellamonica, A Bernar. Persistent viral load in patients on HAART is associated with a higher level of activation-induced apoptosis of CD4(+) T cells. The Journal of antimicrobial chemotherapy. vol 47. issue 1. 2001-03-22. PMID:11152441. |
patients with a viral load > or = 200 copies/ml exhibited a significantly higher level of cd4-induced apoptosis of cd4(+) t cells, compared with patients with undetectable viraemia (38 versus 15%, respectively, p = 0.03). |
2001-03-22 |
2023-08-12 |
human |
| M Spring, C Stahl-Hennig, N Stolte, N Bischofberger, J Heeney, ten Haaft P, K Tenner-Ràcz, P Ràcz, D Lorenzen, G Hunsmann, U Dittme. Enhanced cellular immune response and reduced CD8(+) lymphocyte apoptosis in acutely SIV-infected Rhesus macaques after short-term antiretroviral treatment. Virology. vol 279. issue 1. 2001-03-01. PMID:11145904. |
in contrast, high cd8(+) lymphocyte death but only slightly increased cd4(+) lymphocyte apoptosis were observed during the first weeks after infection in untreated control animals, indicating that early apoptotic death of virus-specific ctl could be an important factor for disease development. |
2001-03-01 |
2023-08-12 |
monkey |
| Nair MPN, S Mahajan, J Hou, A M Sweet, S A Schwart. The stress hormone, cortisol, synergizes with HIV-1 gp-120 to induce apoptosis of normal human peripheral blood mononuclear cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 46. issue 7. 2001-02-22. PMID:11075952. |
both quantitative and qualitative defects in immune functions in patients with aids may result from induction of programmed cell death or apoptosis of cd4 t lymphocytes. |
2001-02-22 |
2023-08-12 |
human |
| J E Talmadge, R Singh, K Ino, A Ageitos, S Buyukberbe. Mechanisms of immune dysfunction in stem cell transplantation. International journal of immunopharmacology. vol 22. issue 12. 2001-02-22. PMID:11137611. |
these studies suggest that 'primed' or activated fas+ cd4+ lymphocytes interact with fasl+ monocytes, resulting in apoptosis, leading to the preferential deletion of cd4+ t cells, a decrease in the cd4:cd8 t cell ratio and depressed t cell function. |
2001-02-22 |
2023-08-12 |
Not clear |
| T Nguyen, W Thomas, X D Zhang, C Gray, P Herse. Immunologically-mediated tumour cell apoptosis: the role of TRAIL in T cell and cytokine-mediated responses to melanoma. Forum (Genoa, Italy). vol 10. issue 3. 2001-02-02. PMID:11007932. |
our studies have shown that cd4 t cells appear to kill melanoma by means of a member of the tumour necrosis factor (tnf) family expressed on their surface and called tnf related apoptosis inducing ligand (trail). |
2001-02-02 |
2023-08-12 |
human |
| M T Esser, J W Bess, K Suryanarayana, E Chertova, D Marti, M Carrington, L O Arthur, J D Lifso. Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1. Journal of virology. vol 75. issue 3. 2001-02-02. PMID:11152488. |
partial activation and induction of apoptosis in cd4(+) and cd8(+) t lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1. |
2001-02-02 |
2023-08-12 |
human |
| M T Esser, J W Bess, K Suryanarayana, E Chertova, D Marti, M Carrington, L O Arthur, J D Lifso. Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1. Journal of virology. vol 75. issue 3. 2001-02-02. PMID:11152488. |
noninfectious cxcr4-tropic hiv-1 virions, but not microvesicles, partially activated freshly isolated cd4(+) and cd8(+) peripheral blood mononuclear cell t lymphocytes to express fasl and fas, but not cd69 or cd25 (interleukin-2 receptor alpha) and eventually die via apoptosis starting 4 to 6 days postexposure. |
2001-02-02 |
2023-08-12 |
human |
| M L Gougeon, E Ledru, H Naora, M Bocchino, H Lecoeu. HIV, cytokines and programmed cell death. A subtle interplay. Annals of the New York Academy of Sciences. vol 926. 2001-02-01. PMID:11193039. |
continuous production of viral proteins leads to an unbalanced immune activation and to the triggering of apoptotic programs, turning mononuclear cells, including cd4 t cells, cd8 t cells and apc, into effectors of apoptosis, leading to fratricidal destruction of healthy uninfected cells expressing the death receptors. |
2001-02-01 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
this study investigated the dynamics of splenic and granuloma cd4(+) th cell apoptosis and fas ligand (fasl) expression during the acute and chronic stages of murine schistosomal infection. |
2001-01-18 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
enhanced apoptosis of freshly isolated cd4(+) th lymphocytes commenced after egg deposition and persisted during the peak and modulated phases of granuloma formation. |
2001-01-18 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
in culture, sea induced splenic and granuloma cd4(+) t-cell apoptosis and stimulated expression of fasl on splenic but not granuloma cd4(+) t cells, cd8(+) t cells, and cd19(+) b cells. |
2001-01-18 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
depletion of b cells from sea-stimulated splenic cultures decreased cd4(+) t cell apoptosis. |
2001-01-18 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
however, cd4(+) t cells were the dominant mediators of apoptosis in the granuloma. |
2001-01-18 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
this study indicates that aicd is involved in the apoptosis of cd4(+) t cells during schistosomal infection. |
2001-01-18 |
2023-08-12 |
Not clear |
| U Mahlknecht, C Deng, M C Lu, T C Greenough, J L Sullivan, W A O'Brien, G Herbei. Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086083. |
apoptosis or programmed cell death may play a critical role in aids pathogenesis through depletion of both cd4(+) and cd8(+) t lymphocytes. |
2001-01-11 |
2023-08-12 |
Not clear |
| U Mahlknecht, C Deng, M C Lu, T C Greenough, J L Sullivan, W A O'Brien, G Herbei. Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086083. |
using a reporter virus, a recombinant hiv infectious clone expressing the green fluorescent protein (gfp), apoptosis was measured in productively infected cd4(+) t lymphocytes, in the presence and absence of autologous macrophages. |
2001-01-11 |
2023-08-12 |
Not clear |
| U Mahlknecht, C Deng, M C Lu, T C Greenough, J L Sullivan, W A O'Brien, G Herbei. Resistance to apoptosis in HIV-infected CD4+ T lymphocytes is mediated by macrophages: role for Nef and immune activation in viral persistence. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086083. |
the presence of macrophages did not reduce apoptosis when cd4(+) t lymphocytes were infected with a gfp-tagged virus deleted for the nef gene. |
2001-01-11 |
2023-08-12 |
Not clear |