| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pingyuan Gong, Jing Li, Jian Wang, Xu Lei, Dongmei Chen, Kejin Zhang, Wenjiang Zhang, Anyuan Zhen, Xiaocai Gao, Fuchang Zhan. Variations in 5-HT2A influence spatial cognitive abilities and working memory. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 38. issue 2. 2011-05-12. PMID:21320838. |
5-hydroxytryptamine receptor 2a (5-ht2a) participates in diverse psychiatric disorders by regulating the activity of serotonin. |
2011-05-12 |
2023-08-12 |
Not clear |
| Hisashi Higuchi, Hitoshi Takahashi, Mitsuhiro Kamata, Keizo Yoshid. Influence of serotonergic/noradrenergic gene polymorphisms on nausea and sweating induced by milnacipran in the treatment of depression. Neuropsychiatric disease and treatment. vol 5. 2011-04-26. PMID:19649213. |
both clinical characteristics prior to the treatment and gene polymorphisms such as serotonin transporter (5-htt) gene-linked polymorphic region (5-httlpr), a variable number of tandem repeats in the second intron of the 5-htt gene (5-httvntr), 5-ht2a receptor gene (5-ht2a g-1438a), a tph gene polymorphism in intron 7 (tph a218c), norepinephrine transporter (net) gene polymorphism in the promoter region (net t-182c) and in the exon 9 (net g1287a), a variable number of tandem repeats in the promoter region of monoamine oxidase a, were items to be assessed in this study. |
2011-04-26 |
2023-08-12 |
Not clear |
| Salvatore Terrazzino, Grazia Sances, Francesca Balsamo, Michele Viana, Francesco Monaco, Giorgio Bellomo, Emilia Martignoni, Cristina Tassorelli, Giuseppe Nappi, Pier Luigi Canonico, Armando A Genazzan. Role of 2 common variants of 5HT2A gene in medication overuse headache. Headache. vol 50. issue 10. 2011-04-25. PMID:20807249. |
the aim of the present study was to evaluate a possible involvement of 2 polymorphisms of the serotonin 5ht2a receptor gene (a-1438g and c516t) as risk factors for medication overuse headache (moh) and whether the presence of these polymorphic variants might determine differences within moh patients in monthly drug consumption. |
2011-04-25 |
2023-08-12 |
Not clear |
| D G Kovalev, I A Zimin, L A Smirnova, A F Riabukh. [Neurochemical mechanisms of antidepressant action of new adenine derivative]. Eksperimental'naia i klinicheskaia farmakologiia. vol 73. issue 12. 2011-04-06. PMID:21395010. |
in addition, the effect of vma-99-82 on binding of 5-ht1a and 5-ht2a serotonin receptors and the system of 3h-serotonin reuptake in the brain synaptosomes has been studied in vitro. |
2011-04-06 |
2023-08-12 |
rat |
| D G Kovalev, I A Zimin, L A Smirnova, A F Riabukh. [Neurochemical mechanisms of antidepressant action of new adenine derivative]. Eksperimental'naia i klinicheskaia farmakologiia. vol 73. issue 12. 2011-04-06. PMID:21395010. |
it is established that vma-99-82 at a dose of 10 mg/kg has no affinity to 5-ht1a and 5-ht2a serotonin receptors and produces no effect on the reuptake of [3h]-5-ht. |
2011-04-06 |
2023-08-12 |
rat |
| Swapna Krishnamoorthy, Zhiyuan Ma, Gongliang Zhang, Jianning Wei, Sidney B Auerbach, Rui Ta. Involvement of 5-HT2A receptors in the serotonin (5-HT) syndrome caused by excessive 5-HT efflux in rat brain. Basic & clinical pharmacology & toxicology. vol 107. issue 4. 2011-03-10. PMID:20456331. |
involvement of 5-ht2a receptors in the serotonin (5-ht) syndrome caused by excessive 5-ht efflux in rat brain. |
2011-03-10 |
2023-08-12 |
rat |
| Leslie Citrom. Lurasidone for schizophrenia: a brief review of a new second-generation antipsychotic. Clinical schizophrenia & related psychoses. vol 4. issue 4. 2011-03-08. PMID:21177242. |
similar to most other second-generation antipsychotics, lurasidone is a full antagonist at dopamine d2 and serotonin 5ht2a receptors. |
2011-03-08 |
2023-08-12 |
Not clear |
| Maria S M Wai, Dietrich E Lorke, W H Kwong, Lihong Zhang, David T Ye. Profiles of serotonin receptors in the developing human thalamus. Psychiatry research. vol 185. issue 1-2. 2011-03-03. PMID:20538346. |
results indicate that, already at 21 weeks of gestation, two 5-ht receptors are present in the dorsomedial nucleus of the developing thalamus: 5-ht2a receptors are localized in neurons and 5-ht2c receptors in fibers. |
2011-03-03 |
2023-08-12 |
human |
| Maria S M Wai, Dietrich E Lorke, W H Kwong, Lihong Zhang, David T Ye. Profiles of serotonin receptors in the developing human thalamus. Psychiatry research. vol 185. issue 1-2. 2011-03-03. PMID:20538346. |
our observation that 5-ht1a, 5-ht2a, 5-ht2c and 5-ht4 receptors are present in the human thalamus prenatally indicates that 5-ht may play a role during fetal development. |
2011-03-03 |
2023-08-12 |
human |
| Georgianna G Gould, Julie G Hensler, Teresa F Burke, Robert H Benno, Emmanuel S Onaivi, Lynette C Daw. Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior. Journal of neurochemistry. vol 116. issue 2. 2011-01-20. PMID:21070242. |
density and function of central serotonin (5-ht) transporters, 5-ht1a and 5-ht2a receptors, and effects of their targeting on btbr t+tf/j mouse social behavior. |
2011-01-20 |
2023-08-12 |
mouse |
| Frederico G Graeff, Hélio Zangross. The dual role of serotonin in defense and the mode of action of antidepressants on generalized anxiety and panic disorders. Central nervous system agents in medicinal chemistry. vol 10. issue 3. 2011-01-07. PMID:20528764. |
the reviewed results suggest that chronic, but not acute, administration of antidepressants suppress panic attacks by increasing the release of 5-ht and enhancing the responsivity of post-synaptic 5-ht1a and 5-ht2a receptors in the dpag. |
2011-01-07 |
2023-08-12 |
human |
| Anders Bue Klein, Viktorija Trajkovska, David Erritzoe, Steven Haugbol, Jacob Madsen, William Baaré, Susana Aznar, Gitte M Knudse. Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 30. issue 11. 2010-11-29. PMID:20736957. |
cerebral 5-ht2a receptor and serotonin transporter binding in humans are not affected by the val66met bdnf polymorphism status or blood bdnf levels. |
2010-11-29 |
2023-08-12 |
human |
| Serap Erdoğa. [Quetiapine in substance use disorders, abuse and dependence possibility: a review]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 21. issue 2. 2010-10-29. PMID:20514567. |
pharmacologically, it has antagonistic effects on serotonin 5-ht1a and 5-ht2a, dopamine d1 and d2, histamine h1, and adrenergic alpha1 and alpha2 receptors. |
2010-10-29 |
2023-08-12 |
Not clear |
| Hiroki Sato, Ivan Skelin, Mirko Diksi. Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study. Brain research. vol 1345. 2010-10-21. PMID:20501324. |
chronic buspirone treatment decreases 5-ht1b receptor densities and the serotonin transporter but increases the density of 5-ht2a receptors in the bulbectomized rat model of depression: an autoradiographic study. |
2010-10-21 |
2023-08-12 |
rat |
| Jun Aoki, Masakazu Hayashida, Megumi Tagami, Makoto Nagashima, Ken-ichi Fukuda, Daisuke Nishizawa, Yasukazu Ogai, Shinya Kasai, Kazutaka Ikeda, Kazuhiko Iwahash. Association between 5-hydroxytryptamine 2A receptor gene polymorphism and postoperative analgesic requirements after major abdominal surgery. Neuroscience letters. vol 479. issue 1. 2010-10-14. PMID:20478362. |
although the serotonin (5-hydroxytryptamine (5-ht)) 2a receptor has been reported to be associated with pain, no relationship has been found between single nucleotide polymorphisms in the 5-ht2a receptor gene and analgesic requirements. |
2010-10-14 |
2023-08-12 |
human |
| Ute Mühlhausen, Wiebke Sihver, Johannes Ermert, Heinz H Coene. Synthesis, radiofluorination and first evaluation of [18F]fluorophenylsulfonyl- and [18F]fluorophenylsulfinyl-piperidines as serotonin 5-HT2A receptor antagonists for PET. Nuclear medicine and biology. vol 37. issue 5. 2010-10-14. PMID:20610165. |
synthesis, radiofluorination and first evaluation of [18f]fluorophenylsulfonyl- and [18f]fluorophenylsulfinyl-piperidines as serotonin 5-ht2a receptor antagonists for pet. |
2010-10-14 |
2023-08-12 |
rat |
| Peter Holm, Anders Ettrup, Anders B Klein, Martin A Santini, Mona El-Sayed, Anders B Elvang, Tine B Stensbøl, Jens D Mikkelsen, Gitte M Knudsen, Susana Azna. Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice. Journal of Alzheimer's disease : JAD. vol 20. issue 4. 2010-10-12. PMID:20413853. |
[3h]-mdl100907, [3h]-escitalopram, and [11c]-pib autoradiography was performed for measuring 5-ht2a receptor, serotonin transporter (sert), and abeta plaque levels in medial prefrontal cortex (mpfc), prefrontal cortex (pfc), frontoparietal cortex (fpc), dorsal and ventral hippocampus, and somatosensory cortex. |
2010-10-12 |
2023-08-12 |
mouse |
| Josè Martin Rabe. Hallucinations and psychosis in Parkinson's disease. Parkinsonism & related disorders. vol 15 Suppl 4. 2010-09-30. PMID:20123547. |
therefore, new atypical antipsychotic drugs with serotonin 5-ht2a receptor inverse agonist properties have been developed. |
2010-09-30 |
2023-08-12 |
Not clear |
| Paweł Kapelski, Joanna Hauser, Maria Skibińska, Aleksandra Szczepankiewicz, Monika Dmitrzak-Weglarz, Bartłomiej Budziński, Karolina Gorzkowska, Piotr M Czersk. [Lack of association between the insertion/deletion polymorphism in serotonin transporter gene, T102C polymorphism of the 5HT2A receptor gene and schizophrenia--family based study]. Psychiatria polska. vol 44. issue 2. 2010-08-30. PMID:20677439. |
[lack of association between the insertion/deletion polymorphism in serotonin transporter gene, t102c polymorphism of the 5ht2a receptor gene and schizophrenia--family based study]. |
2010-08-30 |
2023-08-12 |
Not clear |
| Monika Wiłkość, Joanna Hauser, Marta Tomaszewska, Monika Dmitrzak-Weglarz, Maria Skibińska, Aleksandra Szczepankiewicz, Alina Borkowsk. Influence of dopaminergic and serotoninergic genes on working memory in healthy subjects. Acta neurobiologiae experimentalis. vol 70. issue 1. 2010-07-28. PMID:20407490. |
the purpose of this study was to assess the association between the polymorphisms of dopaminergic (drd1, drd3, drd4, comt) and serotoninergic (sert--serotonin transporter, 5ht2a, 5ht2c) genes' polymorphisms and performance on wcst in 200 volunteers from the polish population. |
2010-07-28 |
2023-08-12 |
human |