| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Akiya Watakabe, Yusuke Komatsu, Osamu Sadakane, Satoshi Shimegi, Toru Takahata, Noriyuki Higo, Shiro Tochitani, Tsutomu Hashikawa, Tomoyuki Naito, Hironobu Osaki, Hiroshi Sakamoto, Masahiro Okamoto, Ayako Ishikawa, Shin-ichiro Hara, Takafumi Akasaki, Hiromichi Sato, Tetsuo Yamamor. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Cerebral cortex (New York, N.Y. : 1991). vol 19. issue 8. 2009-09-16. PMID:19056862. |
to study the molecular mechanism how cortical areas are specialized in adult primates, we searched for area-specific genes in macaque monkeys and found striking enrichment of serotonin (5-hydroxytryptamine, 5-ht) 1b receptor mrna, and to a lesser extent, of 5-ht2a receptor mrna, in the primary visual area (v1). |
2009-09-16 |
2023-08-12 |
monkey |
| Gaku Okugawa, Masaki Kato, Masataka Wakeno, Jun Koh, Masayuki Morikawa, Naoki Matsumoto, Kazuhiro Shinosaki, Hiroshi Yoneda, Toshifumi Kishimoto, Toshihiko Kinoshit. Randomized clinical comparison of perospirone and risperidone in patients with schizophrenia: Kansai Psychiatric Multicenter Study. Psychiatry and clinical neurosciences. vol 63. issue 3. 2009-09-16. PMID:19566763. |
perospirone binds with high affinity to serotonin 5-ht2a receptors and dopamine d2 receptors. |
2009-09-16 |
2023-08-12 |
Not clear |
| Tiffany W Chow, David C Mamo, Hiroyuki Uchida, Ariel Graff-Guerrero, Sylvain Houle, Gwenn S Smith, Bruce G Pollock, Benoit H Mulsan. Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults. BMC medical imaging. vol 9. 2009-09-10. PMID:19580676. |
test-retest variability of high resolution positron emission tomography (pet) imaging of cortical serotonin (5ht2a) receptors in older, healthy adults. |
2009-09-10 |
2023-08-12 |
human |
| Tiffany W Chow, David C Mamo, Hiroyuki Uchida, Ariel Graff-Guerrero, Sylvain Houle, Gwenn S Smith, Bruce G Pollock, Benoit H Mulsan. Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults. BMC medical imaging. vol 9. 2009-09-10. PMID:19580676. |
prior reports indicate a significant normal aging effect on serotonin 5ht2a receptor (5ht2ar) binding potential. |
2009-09-10 |
2023-08-12 |
human |
| Kazuhiko Nakayam. [Mechanism of action of new generation antidepressants under development in Japan: focusing on dopamine neurotransmission]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 29. issue 3. 2009-09-03. PMID:19663259. |
mirtazapine is an antagonist of alpha2, 5-ht2a, and 5-ht2c receptors and promotes releases of na, 5-ht, and da. |
2009-09-03 |
2023-08-12 |
Not clear |
| T G Noskova, A V Kazantseva, A E Gareeva, D A Gaĭsina, S U Tuktarova, E K Khusnutdinov. [Association of several polymorphic loci of serotoninergic genes with unipolar depression]. Genetika. vol 45. issue 6. 2009-08-28. PMID:19639876. |
using pcr-rflp analysis, we have conducted a study of polymorphic loci of several genes of this system: c1019g of serotonin receptor 1a gene, (htr1a); a438g of serotonin receptor 2a gene, (htr2a); g861c of serotonin receptor 1b gene, (htr1b); stin2vntr and 5-httlpr of serotonin transporter gene (slc6a4) in patients with unipolar depression among ethnic tatars and russians. |
2009-08-28 |
2023-08-12 |
Not clear |
| Arun K Tiwari, Renan P Souza, Daniel J Mülle. Pharmacogenetics of anxiolytic drugs. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 6. 2009-08-18. PMID:19434367. |
other significant findings pointed to the serotonin 2a (5-ht2a) receptor and to the tryptophan hydroxylase (tph1) genes. |
2009-08-18 |
2023-08-12 |
Not clear |
| Francesco Angelucci, Sergio Bernardini, Paolo Gravina, Lorenza Bellincampi, Alberto Trequattrini, Fulvia Di Iulio, Diego Vanni, Giorgio Federici, Carlo Caltagirone, Paola Bossù, Gianfranco Spallett. Delusion symptoms and response to antipsychotic treatment are associated with the 5-HT2A receptor polymorphism (102T/C) in Alzheimer's disease: a 3-year follow-up longitudinal study. Journal of Alzheimer's disease : JAD. vol 17. issue 1. 2009-08-12. PMID:19494443. |
in a 3-year follow-up study, we evaluated the association of serotonin (5-ht) receptor 5-ht2a 102t/c polymorphism (allelic variants cc, ct and tt) with psychotic symptom severity and response to treatment with atypical antipsychotics (risperidone, olanzapine and quietapine) in 80 patients with a diagnosis of probable alzheimer's disease. |
2009-08-12 |
2023-08-12 |
Not clear |
| L M Kozhevnikova, A G Davydova, P V Avdoni. [Plasma membrane depolarization and activation of receptors for endogenous vasoconstrictors as possible mechanisms of potentiation of vasoconstrictive response to serotonin in traumatic shock in rats]. Izvestiia Akademii nauk. Seriia biologicheskaia. issue 3. 2009-07-23. PMID:19548619. |
inhibition of serotonin response by ketanserin, a 5ht2a receptor blocker, did not depend on the presence of 15 mm kcl. |
2009-07-23 |
2023-08-12 |
rat |
| Kunie Nakajima, Hideaki Obata, Naomi Ito, Fumio Goto, Shigeru Sait. The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats. European journal of pain (London, England). vol 13. issue 5. 2009-07-15. PMID:18656400. |
therefore, we next examined whether 5-ht2a and 5-ht2c receptors are involved, and from where 5-ht is released in the formalin test. |
2009-07-15 |
2023-08-12 |
rat |
| Kunie Nakajima, Hideaki Obata, Naomi Ito, Fumio Goto, Shigeru Sait. The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats. European journal of pain (London, England). vol 13. issue 5. 2009-07-15. PMID:18656400. |
these results indicate that 5-ht released into peripheral tissue and its receptors, 5-ht2a as well as 5-ht2c, at the periphery have an important role in pain-related behaviors during acute peripheral inflammation. |
2009-07-15 |
2023-08-12 |
rat |
| N K Popova, V S Naumenko, R V Kozhemiakina, I Z Pliusnin. [Functional correlates of the brain 5-HT2A and 5-HT2C serotonin receptors and expression of 5-HT2A AND 5-HT2C genes in aggressive and nonaggressive Norway rats]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 95. issue 2. 2009-06-30. PMID:19368306. |
[functional correlates of the brain 5-ht2a and 5-ht2c serotonin receptors and expression of 5-ht2a and 5-ht2c genes in aggressive and nonaggressive norway rats]. |
2009-06-30 |
2023-08-12 |
rat |
| N K Popova, V S Naumenko, R V Kozhemiakina, I Z Pliusnin. [Functional correlates of the brain 5-HT2A and 5-HT2C serotonin receptors and expression of 5-HT2A AND 5-HT2C genes in aggressive and nonaggressive Norway rats]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 95. issue 2. 2009-06-30. PMID:19368306. |
functional activity of the brain 5-ht2a and 5-ht2c serotonin receptors and expression of 5-ht2a and 5-ht2c genes in norway rats selectively bred for 60 generations for high level and for a lack of fear-induced aggression towards humans were studied. |
2009-06-30 |
2023-08-12 |
rat |
| Xavier López-Gil, Francesc Artigas, Albert Adel. Role of different monoamine receptors controlling MK-801-induced release of serotonin and glutamate in the medial prefrontal cortex: relevance for antipsychotic action. The international journal of neuropsychopharmacology. vol 12. issue 4. 2009-06-26. PMID:18752722. |
to study the contribution of different monoaminergic receptors (for which clozapine and haloperidol exhibit distinct affinities) to these effects, here we used in-vivo microdialysis to examine the role of local blockade of dopamine d2, 5-ht2a and alpha1-adrenergic receptors as well as agonism at dopamine d1 and 5-ht1a receptors in the mpfc on the increased efflux of glutamate and 5-ht elicited by mk-801. |
2009-06-26 |
2023-08-12 |
Not clear |
| Xavier López-Gil, Francesc Artigas, Albert Adel. Role of different monoamine receptors controlling MK-801-induced release of serotonin and glutamate in the medial prefrontal cortex: relevance for antipsychotic action. The international journal of neuropsychopharmacology. vol 12. issue 4. 2009-06-26. PMID:18752722. |
the results show that m100907 (5-ht2a antagonist), bay x 3702 (5-ht1a agonist) and prazosin (alpha1-adrenergic antagonist) blocked the mk-801-induced increase of 5-ht and glutamate in the mpfc. |
2009-06-26 |
2023-08-12 |
Not clear |
| M A Tikhonova, E L Al'perina, T G Tolstikova, D V Bazovkina, V Iu Di, G V Idova, A V Kulikov, N K Popov. [Effects of chronic fluoxetine treatment on catalepsy and immune response in mice genetically predisposed to freezing reaction: the role of 5-HT1A and 5-HT2A receptors and tph2 and SERT genes]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 59. issue 2. 2009-06-19. PMID:19445393. |
no effect on cortical 5-ht1a and 5-ht2a receptor mrna levels and on 5-ht1a receptor, tph2 (tryptophan hydroxylase-2) and sert (serotonin transporter) mesencephalic gene expression was observed in asc mice. |
2009-06-19 |
2023-08-12 |
mouse |
| Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Paweł Kapelski, Maria Skibińska, Magdalena Kaczmarkiewicz-Fass, Joanna Hause. [Association between polymorphisms of ins/del in the 5-HTT gene and T102C in the 5HTR2A gene and the drug response for escitalopram and nortriptyline in depressed patients]. Psychiatria polska. vol 42. issue 6. 2009-06-04. PMID:19441667. |
the role of the serotonin receptor 5ht2a and serotonin transporter 5httlpr polymorphisms was suggested in the pathogenesis of depression and the therapeutic response to serotonergic drugs. |
2009-06-04 |
2023-08-12 |
Not clear |
| B I Gustafsson, L Thommesen, A K Stunes, K Tommeras, I Westbroek, H L Waldum, K Slørdahl, M V Tamburstuen, J E Reseland, U Syverse. Serotonin and fluoxetine modulate bone cell function in vitro. Journal of cellular biochemistry. vol 98. issue 1. 2009-05-29. PMID:16408289. |
proliferation of human mesenchymal stem cells (msc) and primary osteoblasts (nho), and 5-ht2a receptor expression was enhanced by serotonin. |
2009-05-29 |
2023-08-12 |
human |
| B A Nic Dhonnchadha, R G Fox, S J Stutz, K C Rice, K A Cunningha. Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behavioral neuroscience. vol 123. issue 2. 2009-05-18. PMID:19331461. |
blockade of the serotonin 5-ht2a receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. |
2009-05-18 |
2023-08-12 |
rat |
| B A Nic Dhonnchadha, R G Fox, S J Stutz, K C Rice, K A Cunningha. Blockade of the serotonin 5-HT2A receptor suppresses cue-evoked reinstatement of cocaine-seeking behavior in a rat self-administration model. Behavioral neuroscience. vol 123. issue 2. 2009-05-18. PMID:19331461. |
the serotonin 5-ht2a receptor (5-ht-sub(2a)r) may play a role in reinstatement of drug-seeking. |
2009-05-18 |
2023-08-12 |
rat |