Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Aleksey Vorobyev, Hisham Ben Hamidane, Yury O Tsybi. Electron capture dissociation product ion abundances at the X amino acid in RAAAA-X-AAAAK peptides correlate with amino acid polarity and radical stability. Journal of the American Society for Mass Spectrometry. vol 20. issue 12. 2010-02-02. PMID:19811930. |
the correlation factor (r) exceeds 0.9 for 12 amino acids (ile, val, his, asn, asp, glu, gln, ser, thr, gly, cys, and ala). |
2010-02-02 |
2023-08-12 |
Not clear |
D J Black, Anthony Persechin. Variations at the semiconserved glycine in the IQ domain consensus sequence have a major impact on Ca2+-dependent switching in calmodulin-IQ domain complexes. Biochemistry. vol 49. issue 1. 2010-01-28. PMID:19954189. |
we have replaced the semiconserved gly in the iq domain consensus sequence with ala, arg, or met in a reference sequence and determined how this affects its complexes with calmodulin. |
2010-01-28 |
2023-08-12 |
Not clear |
Barbara Manconi, Irene Messana, Federica Maggiani, Alessandra Olianas, Mariagiuseppina Pellegrini, Roberto Crnjar, Massimo Castagnola, Bruno Giardina, Maria Teresa Sann. Structural and functional characterization of Delphinus delphis hemoglobin system. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. vol 179. issue 8. 2010-01-21. PMID:19554331. |
with respect to hba(0), either the substitution probeta5 --> gly or the probeta5 --> ala is present in all the cetacean beta globins sequenced so far, and it has been hypothesized that position 5 of beta globins may have a role in the interaction with 2,3-bpg. |
2010-01-21 |
2023-08-12 |
human |
A Bandegan, W Guenter, D Hoehler, G H Crow, C M Nyachot. Standardized ileal amino acid digestibility in wheat distillers dried grains with solubles for broilers. Poultry science. vol 88. issue 12. 2010-01-21. PMID:19903958. |
the most variable aid estimates of wheat ddgs samples were observed for lys (24.4 to 45.7%), thr (48.2 to 60.9%), and his (57.4 to 69.1%) as indispensable and asp (32.5 to 50.9%), gly (49.6 to 63.1%), and ala (53.6 to 66.8%) as dispensable aa, respectively. |
2010-01-21 |
2023-08-12 |
Not clear |
A Bandegan, W Guenter, D Hoehler, G H Crow, C M Nyachot. Standardized ileal amino acid digestibility in wheat distillers dried grains with solubles for broilers. Poultry science. vol 88. issue 12. 2010-01-21. PMID:19903958. |
apparent ileal digestibility estimates of the wheat sample for lys, thr, his, gly, and ala were 77.5, 74, 83.6, 79.3, and 78.9%, respectively. |
2010-01-21 |
2023-08-12 |
Not clear |
Kristine C Olson, Ryan W Dellinger, Qing Zhong, Dongxiao Sun, Shantu Amin, Thomas E Spratt, Philip Lazaru. Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene. Drug metabolism and disposition: the biological fate of chemicals. vol 37. issue 10. 2010-01-18. PMID:19589876. |
in addition to a previously identified single nucleotide polymorphism (snp) at codon 33 resulting in an amino acid substitution (met>thr), two low-prevalence (<0.02) novel missense snps at codons 167 (val>ala) and 183 (cys>gly) were identified and are present in both white and african-american subjects. |
2010-01-18 |
2023-08-12 |
human |
Michaela Knapp-Mohammady, Alex B Young, Béla Paizs, Alex G Harriso. Fragmentation of doubly-protonated Pro-His-Xaa tripeptides: formation of b(2)(2+) ions. Journal of the American Society for Mass Spectrometry. vol 20. issue 11. 2010-01-18. PMID:19683937. |
when ionized by electrospray from acidic solutions, the tripeptides pro-his-xaa (xaa = gly, ala, leu) form abundant doubly-protonated ions, [m + 2h]2+. |
2010-01-18 |
2023-08-12 |
Not clear |
P Sikiri. The pharmacological properties of the novel peptide BPC 157 (PL-10). Inflammopharmacology. vol 7. issue 1. 2010-01-12. PMID:17657443. |
the reported beneficial effects of the gastric mucosal derived pentadecapeptide bpc 157 (gly glu pro pro pro gly lys pro ala asp asp ala gly leu val, m.w. |
2010-01-12 |
2023-08-12 |
Not clear |
Hengyu Xu, Likai Song, Mikyung Kim, Margaret A Holmes, Zane Kraft, George Sellhorn, Ellis L Reinherz, Leonidas Stamatatos, Roland K Stron. Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity. Journal of virology. vol 84. issue 2. 2010-01-12. PMID:19906921. |
to investigate how 4e10 interacts with membrane and protein components, and whether such interactions contribute to neutralization mechanisms, we introduced two mutations into 4e10 fv constructs, trp to ala at position 100 in the heavy chain [w(h100)a] and gly to glu at position 50 in the light chain [g(l50)e], selected to disrupt potential lipid interactions via different mechanisms. |
2010-01-12 |
2023-08-12 |
human |
Peter van der Gulik, Serge Massar, Dimitri Gilis, Harry Buhrman, Marianne Rooma. The first peptides: the evolutionary transition between prebiotic amino acids and early proteins. Journal of theoretical biology. vol 261. issue 4. 2010-01-08. PMID:19761777. |
we conjecture that the early functional peptides were short (3-8 amino acids long), were made of those amino acids, gly, ala, val and asp, that are abundantly produced in many prebiotic synthesis experiments and observed in meteorites, and that the neutralization of asp's negative charge is achieved by metal ions. |
2010-01-08 |
2023-08-12 |
Not clear |
J W Waggoner, C A Löest, J L Turner, C P Mathis, D M Hallfor. Effects of dietary protein and bacterial lipopolysaccharide infusion on nitrogen metabolism and hormonal responses of growing beef steers. Journal of animal science. vol 87. issue 11. 2010-01-05. PMID:19648488. |
plasma met, thr, leu, ile, phe, trp, gly, ser, asn, and tyr decreased, and plasma ala increased in response to lps (lps x hour; p < 0.01). |
2010-01-05 |
2023-08-12 |
cattle |
Hyun Sook Lee, Yona Cho, Yun-Jae Kim, Tae-Ok Lho, Sun-Shin Cha, Jung-Hyun Lee, Sung Gyun Kan. A novel inorganic pyrophosphatase in Thermococcus onnurineus NA1. FEMS microbiology letters. vol 300. issue 1. 2010-01-05. PMID:19744243. |
the site-specific mutation of the gly residue in motif ii to ala or ser residue exhibited only a slight change in the enzymatic activity and the k(m) value. |
2010-01-05 |
2023-08-12 |
Not clear |
Chenling Qu, Liming Yang, Songcheng Yu, Song Wang, Yuping Bai, Hanqi Zhan. Investigation of the interactions between ginsenosides and amino acids by mass spectrometry and theoretical chemistry. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 74. issue 2. 2009-12-29. PMID:19640776. |
in order to evaluate the essence of the interactions of ginsenosides and proteins which are composed by alpha-amino acids, electrospray ionization mass spectrometry was employed to study the noncovalent interactions between ginsenosides (rb(2), rb(3), re, rg(1) and rh(1)) and 18 kinds of alpha-amino acids (asp, glu, asn, phe, gln, thr, ser, met, trp, val, gly, ile, ala, leu, pro, his, lys and arg). |
2009-12-29 |
2023-08-12 |
Not clear |
Stéphane Baurin, Lionel Vercheval, Fabrice Bouillenne, Claudia Falzone, Alain Brans, Lilian Jacquamet, Jean-Luc Ferrer, Eric Sauvage, Dominique Dehareng, Jean-Marie Frère, Paulette Charlier, Moreno Galleni, Frédéric Kerf. Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry. vol 48. issue 47. 2009-12-17. PMID:19860471. |
substitution of trp154 by gly, ala, or phe yielded noncarboxylated enzymes which displayed poor catalytic efficiencies and reduced stability when compared to the wild-type oxa-10. |
2009-12-17 |
2023-08-12 |
cat |
Yao Zhang, Daniel W Kulp, James D Lear, William F DeGrad. Experimental and computational evaluation of forces directing the association of transmembrane helices. Journal of the American Chemical Society. vol 131. issue 32. 2009-12-14. PMID:19722646. |
analytical ultracentrifugation and equilibrium disulfide interchange show that the stability of ms1 is greatest when gly is at each "a" position of the heptad repeat (ms1-gly), followed by ala > val > ile. |
2009-12-14 |
2023-08-12 |
Not clear |
Shota Atsumi, Zhen Li, James C Lia. Acetolactate synthase from Bacillus subtilis serves as a 2-ketoisovalerate decarboxylase for isobutanol biosynthesis in Escherichia coli. Applied and environmental microbiology. vol 75. issue 19. 2009-12-11. PMID:19684168. |
mutational studies revealed that the replacement of q487 with amino acids with small side chains (ala, ser, and gly) diminished only the decarboxylase activity but maintained the synthase activity. |
2009-12-11 |
2023-08-12 |
Not clear |
Václav Cerovský, Milos Budesínský, Oldrich Hovorka, Josef Cvacka, Zdenek Voburka, Jirina Slaninová, Lenka Borovicková, Vladimír Fucík, Lucie Bednárová, Ivan Votruba, Jakub Strak. Lasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). Chembiochem : a European journal of chemical biology. vol 10. issue 12. 2009-11-30. PMID:19591185. |
to understand the role of this bend on biological activity, we studied lasioglossin analogues in which the gly in the centre of the molecule was replaced by other amino acid residues (ala, lys, pro). |
2009-11-30 |
2023-08-12 |
bee |
Larissa M Podust, Hugues Ouellet, Jens P von Kries, Paul R Ortiz de Montellan. Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. The Journal of biological chemistry. vol 284. issue 37. 2009-11-02. PMID:19605350. |
we suggest a role for the conserved ala(gly)(243)-gly(244) motif in the i-helix in modulating both the binding affinity of the axial water ligand and the ligand selectivity of cytochrome p450 enzymes. |
2009-11-02 |
2023-08-12 |
Not clear |
Shulin Zhao, Yong Huang, Yi-Ming Li. Microchip electrophoresis with chemiluminescence detection for assaying ascorbic acid and amino acids in single cells. Journal of chromatography. A. vol 1216. issue 39. 2009-10-26. PMID:19691964. |
a method based on microchip electrophoresis (mce) with chemiluminescence (cl) detection was developed for the determination of ascorbic acid (aa) and amino acids including tryptophan (trp), glycine (gly) and alanine (ala) present in single cells. |
2009-10-26 |
2023-08-12 |
rat |
Shulin Zhao, Yong Huang, Yi-Ming Li. Microchip electrophoresis with chemiluminescence detection for assaying ascorbic acid and amino acids in single cells. Journal of chromatography. A. vol 1216. issue 39. 2009-10-26. PMID:19691964. |
the average intracellular contents of aa, trp, gly and ala in single rat hepatocytes were found to be 38.3, 5.15, 3.78 and 3.84 fmol (n=12), respectively. |
2009-10-26 |
2023-08-12 |
rat |