| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole Huebener, Stefan Fest, Anne Strandsby, Elke Michalsky, Robert Preissner, Yan Zeng, Gerhard Gaedicke, Holger N Lod. A rationally designed tyrosine hydroxylase DNA vaccine induces specific antineuroblastoma immunity. Molecular cancer therapeutics. vol 7. issue 7. 2008-09-08. PMID:18645033. |
subsequently, a dna minigene vaccine was generated based on the expression vector pcmv-f3ub encoding mutated ubiquitin (gly(76) to ala(76)) and mth3. |
2008-09-08 |
2023-08-12 |
mouse |
| Weiqi Fu, Jianping Lin, Peilin Ce. 5-Aminolevulinate production with recombinant Escherichia coli using a rare codon optimizer host strain. Applied microbiology and biotechnology. vol 75. issue 4. 2008-09-04. PMID:17333171. |
the initial precursors, glycine and succinate, and initial glucose, which is an inhibitor for both ala synthase and dehydratase, were observed to be the key factors affecting ala production. |
2008-09-04 |
2023-08-12 |
Not clear |
| Steven T Whitten, Huan-Wang Yang, Robert O Fox, Vincent J Hilse. Exploring the impact of polyproline II (PII) conformational bias on the binding of peptides to the SEM-5 SH3 domain. Protein science : a publication of the Protein Society. vol 17. issue 7. 2008-08-28. PMID:18577755. |
recently, in work by ferreon and hilser, the energetics associated with ala and gly substitutions at a surface exposed proline site were determined calorimetrically by measuring the binding energetics of sos peptide variants to the c-terminal src homology 3 domain of sem-5. |
2008-08-28 |
2023-08-12 |
Not clear |
| M Katane, T Hanai, T Furuchi, M Sekine, H Homm. Hyperactive mutants of mouse D-aspartate oxidase: mutagenesis of the active site residue serine 308. Amino acids. vol 35. issue 1. 2008-08-19. PMID:18235994. |
recombinant mdaspo carrying a substitution of gly, ala, or tyr for ser-308 was generated, and fused to either his (his-mdaspo), or glutathione s-transferase, his, and s (ghs-mdaspo) at its n-terminus. |
2008-08-19 |
2023-08-12 |
mouse |
| L Cynober, F Blonde, N Lioret, C Coudray-Lucas, S R, J Giboudea. Arterio-venous differences in amino acids, glucose, lactate and fatty acids in burn patients; effect of ornithine alpha-ketoglutarate. Clinical nutrition (Edinburgh, Scotland). vol 5. issue 4. 2008-08-15. PMID:16831775. |
in the control group large negative arterio-venous differences (deltaa-v) were observed in amino acid and lactate levels whereas they were significantly lower with regard to hyp, gly, lys and ala in the okg-treated group. |
2008-08-15 |
2023-08-12 |
Not clear |
| Karunakar Kar, Yuh-Hwa Wang, Barbara Brodsk. Sequence dependence of kinetics and morphology of collagen model peptide self-assembly into higher order structures. Protein science : a publication of the Protein Society. vol 17. issue 6. 2008-08-11. PMID:18441232. |
unexpectedly, the gly to ala replacement interfered with self-assembly of (pro-hyp-gly)(10), while the peptide with a gly to ser substitution self-associated to form a fibrillar structure. |
2008-08-11 |
2023-08-12 |
Not clear |
| Ruxiang Xu, Xiaodan Jiang, Zaiyu Guo, Jianrong Chen, Yuxi Zou, Yiquan Ke, Shizhong Zhang, Zhanhui Li, Yingqian Cai, Mouxuan Du, Lingsha Qin, Yanping Tang, Yanjun Zen. Functional analysis of neuron-like cells differentiated from neural stem cells derived from bone marrow stroma cells in vitro. Cellular and molecular neurobiology. vol 28. issue 4. 2008-08-07. PMID:17902046. |
high-pressure liquid chromatography (hplc) was used to identify neuron-like cells by detecting excitable amino acids [aspartic acid (asp), glutamic acid (glu)], inhibited amino acids [glycine (gly), gamma (gamma) -aminobutyric acid (gaba), alanine (ala)] or monoamines [noradrenaline (ne), 5-hydroxytryptamine (5-ht), dopamine (da)]. |
2008-08-07 |
2023-08-12 |
Not clear |
| Liang-Tsung Huang, M Michael Gromih. Analysis and prediction of protein folding rates using quadratic response surface models. Journal of computational chemistry. vol 29. issue 10. 2008-08-07. PMID:18351617. |
we observed that the polar residues, asn, gln, ser, and lys, are dominant in fast folding proteins whereas the hydrophobic residues, ala, cys, gly, and leu, prefer to be in slow folding proteins. |
2008-08-07 |
2023-08-12 |
Not clear |
| Weiqi Fu, Jianping Lin, Peilin Ce. Enhancement of 5-aminolevulinate production with recombinant Escherichia coli using batch and fed-batch culture system. Bioresource technology. vol 99. issue 11. 2008-08-04. PMID:17993272. |
in batch fermentation, the addition of glucose and glycine was effective to improve ala production. |
2008-08-04 |
2023-08-12 |
Not clear |
| Weiqi Fu, Jianping Lin, Peilin Ce. Enhancement of 5-aminolevulinate production with recombinant Escherichia coli using batch and fed-batch culture system. Bioresource technology. vol 99. issue 11. 2008-08-04. PMID:17993272. |
when the concentrations of succinic acid and glycine were 7.0 g/l and 4.0 g/l, respectively, in the feeding, the ala yield reached 4.1g/l. |
2008-08-04 |
2023-08-12 |
Not clear |
| I M Vasconcelos, J K S Morais, E A Siebra, C R Carlini, D O B Sousa, L M Beltramini, V M M Melo, J T A Oliveir. SBTX, a new toxic protein distinct from soyatoxin and other toxic soybean [Glycine max] proteins, and its inhibitory effect on Cercospora sojina growth. Toxicon : official journal of the International Society on Toxinology. vol 51. issue 6. 2008-07-31. PMID:18328522. |
sbtx contains high levels of glx, ala, asx, gly and lys and showed maximum absorption at 280 nm, epsilon(1cm)(1%) of 6.3, and fluorescence emission in the 290-450 nm range upon excitation at 280nm. |
2008-07-31 |
2023-08-12 |
mouse |
| Yan-Lin Tao, Xun-Jia Cheng, Yong-Feng Fu, Hideo Tsukamoto, Eisaku Yoshihara, Hiroshi Tachiban. Modification of a human monoclonal antibody Fab fragment specific for Plasmodium falciparum 19-kDa C-terminal merozoite surface protein 1 by site-directed mutagenesis. Parasitology research. vol 103. issue 2. 2008-07-29. PMID:18446371. |
no effective replacements for tyr(92) and val(101) were found, but possible substitutions of ile(97) with gly, leu, glu, ala and ser, and of trp(107) with arg and ser were demonstrated. |
2008-07-29 |
2023-08-12 |
human |
| K W Lee, J-W Huh, C M Seon. A new HLA-A*33 variant, HLA-A*3314, identified in a Korean individual. Tissue antigens. vol 71. issue 6. 2008-07-28. PMID:18380773. |
the sequence of human leukocyte antigen (hla)-a*3314 is identical to that of hla-a*330301 except for a single-nucleotide substitution at codon 49 (gcg-->ggg) resulting in an amino acid change from ala to gly. |
2008-07-28 |
2023-08-12 |
human |
| Edward T K Tung, Hoi-Wah Ma, Chiwai Cheng, Boon L Lim, Kam-Bo Won. Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions. Protein and peptide letters. vol 15. issue 3. 2008-07-21. PMID:18336361. |
stabilization of beta-propeller phytase by introducing xaa-->pro and gly-->ala substitutions at consensus positions. |
2008-07-21 |
2023-08-12 |
Not clear |
| Edward T K Tung, Hoi-Wah Ma, Chiwai Cheng, Boon L Lim, Kam-Bo Won. Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions. Protein and peptide letters. vol 15. issue 3. 2008-07-21. PMID:18336361. |
in this study, the stability of a beta-propeller phytase, phyl, from bacillus licheniformis was successfully improved by introducing xaa-->pro and gly-->ala substitutions at consensus positions. |
2008-07-21 |
2023-08-12 |
Not clear |
| Edward T K Tung, Hoi-Wah Ma, Chiwai Cheng, Boon L Lim, Kam-Bo Won. Stabilization of beta-propeller phytase by introducing Xaa-->Pro and Gly-->Ala substitutions at consensus positions. Protein and peptide letters. vol 15. issue 3. 2008-07-21. PMID:18336361. |
our results suggest that gly-->ala substitution is a more promising strategy to improve protein stability. |
2008-07-21 |
2023-08-12 |
Not clear |
| Tetsuya Kotani, Hiroshi Takag. Identification of amino acid residues essential for the yeast N-acetyltransferase Mpr1 activity by site-directed mutagenesis. FEMS yeast research. vol 8. issue 4. 2008-07-16. PMID:18373682. |
the replacement of arg145, which is conserved in the gnat superfamily, by ala, asp, glu, gly, or trp led to a growth defect of transformants grown in the presence of azc. |
2008-07-16 |
2023-08-12 |
cat |
| Kosuke Fujishima, Junichi Sugahara, Masaru Tomita, Akio Kana. Sequence evidence in the archaeal genomes that tRNAs emerged through the combination of ancestral genes as 5' and 3' tRNA halves. PloS one. vol 3. issue 2. 2008-07-15. PMID:18286179. |
we found not only universally conserved combinations of 5'-3' trna halves in trna(imet), trna(thr), trna(ile), trna(gly), trna(gln), trna(glu), trna(asp), trna(lys), trna(arg) and trna(leu) but also phylum-specific combinations in trna(pro), trna(ala), and trna(trp). |
2008-07-15 |
2023-08-12 |
Not clear |
| H Y Qiao, J P Dahiya, H L Classe. Nutritional and physiological effects of dietary sinapic acid (4-hydroxy-3,5-dimethoxy-cinnamic acid) in broiler chickens and its metabolism in the digestive tract. Poultry science. vol 87. issue 4. 2008-07-10. PMID:18339994. |
a negative linear relationship was found between dietary sa level and apparent ileal digestibility of met, thr, ser, pro, gly, ala, and phe. |
2008-07-10 |
2023-08-12 |
Not clear |
| Nahoko Nagasaki, Rie Tomioka, Masayoshi Maeshim. A hydrophilic cation-binding protein of Arabidopsis thaliana, AtPCaP1, is localized to plasma membrane via N-myristoylation and interacts with calmodulin and the phosphatidylinositol phosphates PtdIns(3,4,5)P(3) and PtdIns(3,5)P(2). The FEBS journal. vol 275. issue 9. 2008-07-09. PMID:18397324. |
the amino-terminal sequence of 27 residues of pcap1 had a potential to localize the fusion protein with green fluorescent protein to the plasma membrane, and the substitution of gly at position 2 with ala resulted in the cytoplasmic localization of pcap1. |
2008-07-09 |
2023-08-12 |
Not clear |