| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sun Hur, Thomas C Bruic. The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin. Journal of the American Chemical Society. vol 124. issue 25. 2002-08-19. PMID:12071739. |
repositioning of the n-terminal part of the peptide on cyp.ts formation becomes more pronounced when the substrate x residue is changed from gly < trp < ala < leu. |
2002-08-19 |
2023-08-12 |
Not clear |
| A I Kishore, M E Herberstein, C L Craig, F Separovi. Solid-state NMR relaxation studies of Australian spider silks. Biopolymers. vol 61. issue 4. 2002-08-19. PMID:12115143. |
a comparison of (13)c-t(1) and (1)h-t(1rho) solid-state nmr relaxation data of the ala calpha, ala cbeta, gly calpha, and carbonyl resonances revealed subtle differences between dragline and cocoon silk. |
2002-08-19 |
2023-08-12 |
spider |
| Julian G B Northey, Karen L Maxwell, Alan R Davidso. Protein folding kinetics beyond the phi value: using multiple amino acid substitutions to investigate the structure of the SH3 domain folding transition state. Journal of molecular biology. vol 320. issue 2. 2002-08-09. PMID:12079394. |
in contrast to most other folding kinetics studies which have focused primarily on non-disruptive substitutions with ala or gly, here we have examined the effects of substitutions with diverse amino acid residues. |
2002-08-09 |
2023-08-12 |
Not clear |
| Till Opatz, Rob M J Liskam. Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders. Journal of combinatorial chemistry. vol 4. issue 4. 2002-08-06. PMID:12099844. |
in the synthesis of the first library, the two outer arms consisted of amino acid ala, arg, asp, gln, gly, lys, phe, ser, tyr, or val and the middle arm consisted of amino acid asn, glu, his, leu, or pro. |
2002-08-06 |
2023-08-12 |
Not clear |
| Till Opatz, Rob M J Liskam. Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders. Journal of combinatorial chemistry. vol 4. issue 4. 2002-08-06. PMID:12099844. |
the first outer arm consisted of amino acid(s) ala, arg, gln, phe, or ser, the second outer arm consisted of amino acid(s) asp, gly, lys, tyr, or val, and the middle arm consisted of amino acid(s) asn, glu, his, leu, or pro, leading to a 27 000 member library of synthetic tripodal receptor molecules. |
2002-08-06 |
2023-08-12 |
Not clear |
| J Bujdák, B M Rod. Preferential amino acid sequences in alumina-catalyzed peptide bond formation. Journal of inorganic biochemistry. vol 90. issue 1-2. 2002-07-24. PMID:12009249. |
the readiness of amino acids to form peptide sequences was estimated on the basis of the yield of dipeptides and was found to decrease in the order glycine (gly), alanine (ala), leucine (leu), valine (val), proline (pro). |
2002-07-24 |
2023-08-12 |
Not clear |
| E A Permiakov, S E Permiakov, V N Medvedki. [Kinetics and mechanism of peptide synthesis in solution]. Bioorganicheskaia khimiia. vol 28. issue 1. 2002-07-22. PMID:11875968. |
the kinetics of the reaction of boc-xaa fluorophenyl esters (where xaa = ala, val, phe, ser, leu, gly, met, pro, or ile) with leucinamide was studied measuring changes in the fluorescence emission at 375 nm of the fluorophenyl chromophore accompanying the reaction. |
2002-07-22 |
2023-08-12 |
Not clear |
| E A Permiakov, S E Permiakov, V N Medvedki. [Kinetics and mechanism of peptide synthesis in solution]. Bioorganicheskaia khimiia. vol 28. issue 1. 2002-07-22. PMID:11875968. |
the a and b reaction orders were close to 1/2 and 3/2 for xaa = ala, val, phe, ser, or leu, 1/2 and 1 for gly, met, or pro, and 1 and 2 for ile. |
2002-07-22 |
2023-08-12 |
Not clear |
| Michal Zurovec, Frantisek Sehna. Unique molecular architecture of silk fibroin in the waxmoth, Galleria mellonella. The Journal of biological chemistry. vol 277. issue 25. 2002-07-19. PMID:11886872. |
the repeats contain a high proportion of gly (31.6%), ala (23.8%), ser (18.1%), and of residues with long hydrophobic side chains (16% for leu, ile, and val combined). |
2002-07-19 |
2023-08-12 |
bee |
| Tsunenori Kameda, Yasumoto Nakazawa, Junko Kazuhara, Tsutomu Yamane, Tetsuo Asakur. Determination of intermolecular distance for a model peptide of Bombyx mori silk fibroin, GAGAG, with rotational echo double resonance. Biopolymers. vol 64. issue 2. 2002-07-02. PMID:11979518. |
rotational echo double resonance nmr spectroscopy is applied for the determination of the distance of intermolecular chains of pentapeptide, gagag (g: gly, a: ala), a model typical of the crystalline domain in bombyx mori silk fibroin. |
2002-07-02 |
2023-08-12 |
Not clear |
| Manjiri Bhate, Xin Wang, Jean Baum, Barbara Brodsk. Folding and conformational consequences of glycine to alanine replacements at different positions in a collagen model peptide. Biochemistry. vol 41. issue 20. 2002-06-28. PMID:12009919. |
in osteogenesis imperfecta (oi) and other collagen diseases, single base mutations often convert one gly to a larger residue, and t1-892 homologues modeling such mutations were synthesized with gly to ala substitutions in either the (gly-pro-hyp)(4) domain, gly25ala, or the (gly-x-y)(6) domain, gly10ala. |
2002-06-28 |
2023-08-12 |
Not clear |
| Manjiri Bhate, Xin Wang, Jean Baum, Barbara Brodsk. Folding and conformational consequences of glycine to alanine replacements at different positions in a collagen model peptide. Biochemistry. vol 41. issue 20. 2002-06-28. PMID:12009919. |
cd and nmr studies show the gly10ala peptide forms a normal triple-helix at the c-terminal end and propagates from the c- to the n-terminus until the gly --> ala substitution is encountered. |
2002-06-28 |
2023-08-12 |
Not clear |
| Manjiri Bhate, Xin Wang, Jean Baum, Barbara Brodsk. Folding and conformational consequences of glycine to alanine replacements at different positions in a collagen model peptide. Biochemistry. vol 41. issue 20. 2002-06-28. PMID:12009919. |
in contrast, introduction of the gly to ala replacement at position 25, in the nucleation domain, shifts the monomer/trimer equilibrium toward the monomer form. |
2002-06-28 |
2023-08-12 |
Not clear |
| Manjiri Bhate, Xin Wang, Jean Baum, Barbara Brodsk. Folding and conformational consequences of glycine to alanine replacements at different positions in a collagen model peptide. Biochemistry. vol 41. issue 20. 2002-06-28. PMID:12009919. |
the specific consequences of gly to ala replacements in two distinctive sequences in this triple-helical peptide may help clarify the variability in oi clinical severity resulting from mutations at different sites along type i collagen chains. |
2002-06-28 |
2023-08-12 |
Not clear |
| Kazuo Shiomi, Yoko Kawashima, Masakazu Mizukami, Yuji Nagashim. Properties of proteinaceous toxins in the salivary gland of the marine gastropod (Monoplex echo). Toxicon : official journal of the International Society on Toxinology. vol 40. issue 5. 2002-06-18. PMID:11821129. |
amino acid compositions of echotoxins 1a, 1b, and 2 are closely similar to one another, being characterized by the abundance of gly and ala and the absence of half-cys, met, and trp. |
2002-06-18 |
2023-08-12 |
mouse |
| W Szeszel-Fedorowicz, G Rosiński, J Issberner, R Osborne, J Sliwowska, D Konopińsk. Myotropic effects of new proctolin analogues modified in the position 5 of peptide chain in insects. Polish journal of pharmacology. vol 53. issue 1. 2002-06-13. PMID:11785908. |
to explain the role of the thr5 residue of proctolin (arg-tyr-leu-pro-thr) in the myotropic activity of this insect neuropeptide, we synthesized two groups of its analogues: 1) arg-tyr-leu-pro-x-oh with x = val (1), d-val (2), ile (3), d-ile (4), ala (5), d-ala (6), asn (7), gln (8), ser (9), pro (10), phe (11), asp (12), glu (13), arg (14), d-arg (15), lys (16) and gly (17) and 2) arg-tyr-leu-pro-r', where r' = isobutylamine (18), s-1-methyl-1-phenylmethylamine (19), r-1-methyl-1-phenylmethylamine (20), r-2-amino-1-propanol (21), s-2-amino-1-propanol (22), r-1-amino-2-propanol (23), s-2-amino-1-propanol (24), 3-amino-1-propanol (25). |
2002-06-13 |
2023-08-12 |
Not clear |
| Richard J Balment, Maria A Masini, Mauro Vallarino, J Michael Conlo. Cardiovascular actions of lungfish bradykinin in the unanaesthetised African lungfish, Protopterus annectens. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 131. issue 2. 2002-05-31. PMID:11818234. |
bradykinin (bk) isolated from plasma of the african lungfish, protopterus annectens, contains four amino acid substitutions compared with bk from mammals (arg(1)-->tyr, pro(2)-->gly, pro(7)-->ala, phe(8)-->pro). |
2002-05-31 |
2023-08-12 |
Not clear |
| Tsuyoshi Saito, Yoshinao Oda, Akio Sakamoto, Ken-ichi Kawaguchi, Kazuhiro Tanaka, Shuichi Matsuda, Sadafumi Tamiya, Yukihide Iwamoto, Masazumi Tsuneyosh. APC mutations in synovial sarcoma. The Journal of pathology. vol 196. issue 4. 2002-05-28. PMID:11920741. |
the mutational sites comprised one case each at codons 1299 (gct to act, ala to thr), 1412 (gga to aga, gly to arg), and 1414 (gta to ata, val to ile), in addition to one case with double point mutations at codon 1398 (agt to aat, ser to asn) and at codon 1413 (atg to ata, met to ile), together with beta-catenin mutation at codon 32 (gac to tac, asp to tyr). |
2002-05-28 |
2023-08-12 |
Not clear |
| T Wurch, D Junquero, A Delhon, J Pauwel. Pharmacological analysis of wild-type alpha, gamma and delta subtypes of the human peroxisome proliferator-activated receptor. Naunyn-Schmiedeberg's archives of pharmacology. vol 365. issue 2. 2002-05-03. PMID:11819031. |
whereas the ppardelta subtype perfectly matched the amino acid sequences reported in the genbank database, several differences were found for the pparalpha (lys(123)met, ala(268)val, gly(296)ala and val(444)ala) and ppargamma2 (met(8)ile, pro(9)ala, met(186)ile, pro(187)ala and the deletion of a gln(213) residue) subtypes. |
2002-05-03 |
2023-08-12 |
human |
| P M St Hilaire, L C Alves, S J Sanderson, J C Mottram, M A Juliano, L Juliano, G H Coombs, M Melda. The substrate specificity of a recombinant cysteine protease from Leishmania mexicana: application of a combinatorial peptide library approach. Chembiochem : a European journal of chemical biology. vol 1. issue 2. 2002-04-29. PMID:11828405. |
generally, the specificity of the primed subsites was less strict compared with the non-primed side which showed preference for arg, lys and ala in s'(1), arg, pro and gly in s'(2) and lys, arg and ser in s'(4). |
2002-04-29 |
2023-08-12 |
cat |