| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Canavese, D Gabrielli, C Guida, M D Cappellin. [Nephrologists and porphyrias]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. vol 19. issue 4. 2002-12-16. PMID:12369042. |
following the "trigger" enzyme delta-aminolevulinic acid (ala) synthase, which is capable of condensing succynil coa and glycine, seven additional enzymes are involved in the process that eventually leads to haeme biosynthesis. |
2002-12-16 |
2023-08-12 |
human |
| Xiao-Zhen Liang, Bernett T K Lee, Sek-Man Won. Covariation in the capsid protein of hibiscus chlorotic ringspot virus induced by serial passaging in a host that restricts movement leads to avirulence in its systemic host. Journal of virology. vol 76. issue 23. 2002-12-13. PMID:12414972. |
a remarkable covariation of eight site-specific amino acids was found in the hcrsv capsid protein (cp) after serial passages in c. quinoa: val(49)-->ile, ile(95)-->val, lys(270)-->arg, gly(272)-->asp, tyr(274)-->his, ala(311)-->asp, asp(334)-->ala, and ala(335)-->thr. |
2002-12-13 |
2023-08-12 |
Not clear |
| K Takano, K Tsuchimori, Y Yamagata, K Yutan. Effect of foreign N-terminal residues on the conformational stability of human lysozyme. European journal of biochemistry. vol 266. issue 2. 2002-12-03. PMID:10561612. |
to minutely understand the effect of foreign n-terminal residues on the conformational stability of human lysozyme, five mutant proteins were constructed: two had met or ala in place of the n-terminal lys residue (k1m and k1a, respectively), and others had one additional residue, met, gly or pro, to the n-terminal lys residue (met(-1), gly(-1) and pro(-1), respectively). |
2002-12-03 |
2023-08-12 |
human |
| Li Zhang, Takashi Kudo, Naoki Takaya, Hirofumi Shou. The B' helix determines cytochrome P450nor specificity for the electron donors NADH and NADPH. The Journal of biological chemistry. vol 277. issue 37. 2002-12-03. PMID:12105197. |
the b' helix region of tnor ((73)saggkaaa(80)) contains some ala and gly residues, whereas the sequence is replaced at a few sites with more bulky amino acid residues in fnor ((73)sasgkqaa(80)). |
2002-12-03 |
2023-08-12 |
Not clear |
| S Ganesh, R Jayakuma. Role of N-t-Boc group in helix initiation in a novel tetrapeptide. The journal of peptide research : official journal of the American Peptide Society. vol 59. issue 6. 2002-11-27. PMID:12010515. |
conformational analysis of tetrapeptide derivatives containing ala, ile and gly residues was performed. |
2002-11-27 |
2023-08-12 |
Not clear |
| Mads Toustrup-Jensen, Bente Vilse. Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12149251. |
in mutants glu(282) --> lys and glu(282) --> asp, the e(1) form was favored during atp hydrolysis, whereas the e(2) form was favored in glu(282) --> ala and glu(282) --> gly. |
2002-11-25 |
2023-08-12 |
Not clear |
| Mads Toustrup-Jensen, Bente Vilse. Importance of Glu(282) in transmembrane segment M3 of the Na(+),K(+)-ATPase for control of cation interaction and conformational changes. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12149251. |
glu(282) --> ala and glu(282) --> gly exhibited an extraordinary high rate of atp hydrolysis in the mere presence of na(+) without k(+) ("na(+)-atpase activity"), because of an increased rate of dephosphorylation of e(2)p. these results are in accordance with the hypothesis that glu(282) is involved in the communication between the cation binding pocket and the catalytic site and in control of the cytoplasmic entry pathway for na(+). |
2002-11-25 |
2023-08-12 |
Not clear |
| Hideo Nishino, Atsuko Kosaka, Guy A Hembury, Fumiko Aoki, Koji Miyauchi, Hiroshi Shitomi, Hideo Onuki, Yoshihisa Inou. Absolute asymmetric photoreactions of aliphatic amino acids by circularly polarized synchrotron radiation: critically pH-dependent photobehavior. Journal of the American Chemical Society. vol 124. issue 39. 2002-11-19. PMID:12296726. |
in the case of amino acids lacking a gamma-hydrogen, such as glycine and ala, the photodecomposition mechanism is a photodeamination/hydroxylation and a norrish type i reaction. |
2002-11-19 |
2023-08-12 |
Not clear |
| Sergio G Peisajovich, Raquel F Epand, Richard M Epand, Yechiel Sha. Sendai virus N-terminal fusion peptide consists of two similar repeats, both of which contribute to membrane fusion. European journal of biochemistry. vol 269. issue 17. 2002-11-05. PMID:12199713. |
based on these experiments, we postulate that replacement of gly 7 and gly12 by ala increases the alpha helical content of the n-terminal region, with a concomitant increase in its fusogenic activity. |
2002-11-05 |
2023-08-12 |
Not clear |
| Yasumoto Nakazawa, Tetsuo Asakur. Heterogeneous exchange behavior of Samia cynthia ricini silk fibroin during helix-coil transition studied with (13)C NMR. FEBS letters. vol 529. issue 2-3. 2002-11-05. PMID:12372598. |
the structure and structural transition of the glycine residue adjacent to the n-terminal alanine residue of the poly(l-alanine), (ala)(12-13), region in samia cynthia ricini silk fibroin was studied using (13)c nuclear magnetic resonance (nmr). |
2002-11-05 |
2023-08-12 |
Not clear |
| Yasumoto Nakazawa, Tetsuo Asakur. Heterogeneous exchange behavior of Samia cynthia ricini silk fibroin during helix-coil transition studied with (13)C NMR. FEBS letters. vol 529. issue 2-3. 2002-11-05. PMID:12372598. |
the slow exchange between helix and coil forms in the nmr time scale was observed with increasing temperature exclusively for the underlined glycine residue in the gly-gly-(ala)(12-13) sequence during fast helix-coil transition of the (ala)(12-13) region. |
2002-11-05 |
2023-08-12 |
Not clear |
| Margarita M Monastyrnaya, Tatyana A Zykova, Olga V Apalikova, Tatyana V Shwets, Emma P Kozlovskay. Biologically active polypeptides from the tropical sea anemone Radianthus macrodactylus. Toxicon : official journal of the International Society on Toxinology. vol 40. issue 8. 2002-11-04. PMID:12165324. |
the relative molecular weight of high molecular weight radianthus cytolysins named according to their n-terminal amino acids rtx-a (ala), rtx-s (ser) and rtx-g (gly) was about 20,000. |
2002-11-04 |
2023-08-12 |
Not clear |
| Susan Lorey, Jurgen Faust, Carmen Mrestani-Klaus, Thilo Kähne, Siegfried Ansorge, Klaus Neubert, Frank Bühlin. Transcellular proteolysis demonstrated by novel cell surface-associated substrates of dipeptidyl peptidase IV (CD26). The Journal of biological chemistry. vol 277. issue 36. 2002-10-29. PMID:12095981. |
rhodamine 110 (r110), a highly fluorescent xanthene dye, was used to synthesize dipeptidyl peptidase iv (dp iv/cd26) substrates gly(ala)-pro-r110-r, thus facilitating a stable binding of the fluorescent moiety on the cell surface. |
2002-10-29 |
2023-08-12 |
Not clear |
| Ana M Edwards, Marcelo Ruiz, Eduardo Silva, Eduardo Liss. Lysozyme modification by the fenton reaction and gamma radiation. Free radical research. vol 36. issue 3. 2002-10-28. PMID:12071346. |
the modification order was tyr > met = cys > lys > ile + leu > gly > pro = phe > thr + ala > trp = ser > arg > asp + glu, with 42 mol of modified residues per initial mole of native enzyme. |
2002-10-28 |
2023-08-12 |
Not clear |
| Qian Dong, Wenrui Jin, Jihao Sha. Analysis of amino acids by capillary zone electrophoresis with electrochemical detection. Electrophoresis. vol 23. issue 4. 2002-10-08. PMID:11870765. |
from a mixture of 19 amino acids, 10 amino acids (arg, lys, orn, try, ser, ala, gly, cys, glu, asp) could be well separated. |
2002-10-08 |
2023-08-12 |
Not clear |
| Markus Eilers, Ashish B Patel, Wei Liu, Steven O Smit. Comparison of helix interactions in membrane and soluble alpha-bundle proteins. Biophysical journal. vol 82. issue 5. 2002-09-24. PMID:11964258. |
we show that the most abundant tightly packed interfacial residues in membrane proteins are gly, ala, and ser, and that helices with left-handed crossing angles are more tightly packed on average than helices with right-handed crossing angles. |
2002-09-24 |
2023-08-12 |
Not clear |
| Markus Eilers, Ashish B Patel, Wei Liu, Steven O Smit. Comparison of helix interactions in membrane and soluble alpha-bundle proteins. Biophysical journal. vol 82. issue 5. 2002-09-24. PMID:11964258. |
however, a second motif for mediating helix interactions is revealed by the high occurrence and high average packing values of small and polar residues (ala, gly, ser, thr) in the helix interfaces of membrane proteins. |
2002-09-24 |
2023-08-12 |
Not clear |
| Marta Toth, Sonia Hernandez-Barrantes, Pamela Osenkowski, M Margarida Bernardo, David C Gervasi, Yoichiro Shimura, Oussama Meroueh, Lakshmi P Kotra, Beatriz G Gálvez, Alicia G Arroyo, Shahriar Mobashery, Rafael Fridma. Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme. The Journal of biological chemistry. vol 277. issue 29. 2002-09-06. PMID:12004057. |
structural and sequencing data indicate that shedding of the 18-kda fragment is initiated at the gly(284)-gly(285) site, followed by cleavage between the conserved ala(255) and ile(256) residues near the conserved methionine turn, a structural feature of the catalytic domain of all mmps. |
2002-09-06 |
2023-08-12 |
Not clear |
| Kenji Ikehara, Yoko Omori, Rieko Arai, Akiko Hiros. A novel theory on the origin of the genetic code: a GNC-SNS hypothesis. Journal of molecular evolution. vol 54. issue 4. 2002-08-23. PMID:11956691. |
four amino acids (gly [g], ala [a], asp [d], and val [v]) encoded by the gnc code satisfied the four structural conditions well, but other codes in rows and columns in the universal genetic code table do not, except for the gng code, a slightly modified form of the gnc code. |
2002-08-23 |
2023-08-12 |
Not clear |
| Sun Hur, Thomas C Bruic. The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin. Journal of the American Chemical Society. vol 124. issue 25. 2002-08-19. PMID:12071739. |
the md simulations include four enzyme-bound species of tetrapeptide (suc-ala-xc([double bond]o)-npro-phe-pna; x = gly, trp, ala, and leu). |
2002-08-19 |
2023-08-12 |
Not clear |