Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Shuquan Zhang, Minfei Wu, Chuangang Peng, Guanjie Zhao, Rui G. GFAP expression in injured astrocytes in rats. Experimental and therapeutic medicine. vol 14. issue 3. 2020-09-30. PMID:28962102. |
we analyzed the activated astrocyte markers gfap and 14-3-3ε by western blot analysis and found that both increased over time, starting at 4 h and reaching the highest level at 72 h, at the end of the experiment. |
2020-09-30 |
2023-08-13 |
rat |
Constanza Stefania Meneses, Heine Yacob Müller, Daniel Eduardo Herzberg, Benjamín Uberti, Hedie Almagro Bustamante, Marianne Patricia Werne. Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. PeerJ. vol 5. 2020-09-30. PMID:29085760. |
astrocyte primary stem branches (and cellular bodies to a much lesser extent) are mainly detected using gfap. |
2020-09-30 |
2023-08-13 |
human |
S Nishiyama, T Misu, M Nuriya, R Takano, T Takahashi, I Nakashima, M Yasui, Y Itoyama, M Aoki, K Fujihar. Complement-dependent and -independent aquaporin 4-antibody-mediated cytotoxicity in human astrocytes: Pathogenetic implications in neuromyelitis optica. Biochemistry and biophysics reports. vol 7. 2020-09-30. PMID:29114578. |
pathological studies on nmo have revealed extensive astrocytic damage, as evidenced by the loss of aqp4 and glial fibrillary acidic protein (gfap), specifically in perivascular regions with immunoglobulin and complement depositions, although other pathological patterns, such as a loss of aqp4 without astrocyte destruction and clasmatodendrosis, have also been observed. |
2020-09-30 |
2023-08-13 |
human |
Jie X. New Insights into GFAP Negative Astrocytes in Calbindin D28k Immunoreactive Astrocytes. Brain sciences. vol 8. issue 8. 2020-09-30. PMID:30081456. |
in order to characterize the properties of gfap in calbindin d28k immunoreactive astrocytes, we use primary astrocyte cultures from cells of new-born mice. |
2020-09-30 |
2023-08-13 |
mouse |
Qian Sun, Ming Ying, Quan Ma, Zhijun Huang, Liangyu Zou, Jianjun Liu, Zhixiong Zhuang, Xifei Yan. Proteomic analysis of hippocampus in mice following long-term exposure to low levels of copper. Toxicology research. vol 5. issue 4. 2020-09-30. PMID:30090419. |
the increased expression of gfap, an astrocyte marker, indicated that long-term low levels of copper exposure caused activation of the inflammatory response, a process linked to spatial memory impairment. |
2020-09-30 |
2023-08-13 |
mouse |
Jing Han, Ji-Zhou Zhang, Zhi-Feng Zhong, Zuan-Fang Li, Wen-Sheng Pang, Juan Hu, Li-Dian Che. Neural regeneration research. vol 13. issue 8. 2020-09-30. PMID:30106053. |
immunofluorescence staining was used to examine cell proliferation using the marker 5-bromo-2'-deoxyuridine (brdu) as well as expression of the neural precursor marker doublecortin (dcx), the astrocyte marker glial fibrillary acidic protein (gfap) and the axon regeneration marker growth associated protein-43 (gap-43). |
2020-09-30 |
2023-08-13 |
rat |
Saumitra S Singh, Sachchida N Rai, Hareram Birla, Walia Zahra, Gaurav Kumar, Mallikarjuna R Gedda, Neeraj Tiwari, Ranjana Patnaik, Rakesh K Singh, Surya P Sing. Effect of Chlorogenic Acid Supplementation in MPTP-Intoxicated Mouse. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:30127737. |
moreover, reduced gfap staining within the nigrostriatal region has supported the fact that cga has significantly helped in the attenuation of astrocyte activation. |
2020-09-30 |
2023-08-13 |
mouse |
Chuanqi Sun, Yasuko Fukushi, Yong Wang, Seiji Yamamot. Astrocytes Protect Neurons in the Hippocampal CA3 Against Ischemia by Suppressing the Intracellular Ca Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:30197589. |
immunofluorescence staining of glial fibrillary acidic protein (gfap) was used to evaluate the effect of l-α-aaa on astrocyte numbers. |
2020-09-30 |
2023-08-13 |
rat |
Lucas D Udovin, Tamara Kobiec, María I Herrera, Nicolás Toro-Urrego, Carlos F Kusnier, Rodolfo A Kölliker-Frers, Ana B Ramos-Hryb, Juan P Luaces, Matilde Otero-Losada, Francisco Capan. Partial Reversal of Striatal Damage by Palmitoylethanolamide Administration Following Perinatal Asphyxia. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31969800. |
after 30 days, the animals were perfused, and coronal striatal sections were collected to analyze protein-level expression by western blot and the reactive area by immunohistochemistry for neuron markers: phosphorylated neurofilament-heavy/medium-chain (pnf-h/m) and microtubule-associated protein-2 (map-2), and the astrocyte marker, glial fibrillary acidic protein (gfap). |
2020-09-30 |
2023-08-13 |
rat |
Ping Wang, Danian Qin, Yu-Feng Wan. Oxytocin Rapidly Changes Astrocytic GFAP Plasticity by Differentially Modulating the Expressions of pERK 1/2 and Protein Kinase A. Frontiers in molecular neuroscience. vol 10. 2020-09-29. PMID:28860967. |
in lysates of the son, ot receptors (otrs) were co-immunoprecipitated with gfap; vasopressin (vp), a neuropeptide structurally similar to ot, did not significantly change gfap protein level; ot-evoked depolarization of astrocyte membrane potential was sensitive to a selective otr antagonist (otra) but not to tetanus toxin, a blocker of synaptic transmission. |
2020-09-29 |
2023-08-13 |
rat |
Ping Wang, Danian Qin, Yu-Feng Wan. Oxytocin Rapidly Changes Astrocytic GFAP Plasticity by Differentially Modulating the Expressions of pERK 1/2 and Protein Kinase A. Frontiers in molecular neuroscience. vol 10. 2020-09-29. PMID:28860967. |
the effects of ot on gfap expression and on astrocyte uptake of bauer-peptide, an astrocyte-specific dye, were mimicked by isoproterenol (ipt; β-adrenoceptor agonist), u0126 or pd98059, inhibitors of extracellular signal-regulated protein kinase (erk) 1/2 kinase and blocked by the otra or kt5720, a protein kinase a (pka) inhibitor. |
2020-09-29 |
2023-08-13 |
rat |
Stefan Christopher Weise, Alejandro Villarreal, Stefanie Heidrich, Fariba Dehghanian, Christian Schachtrup, Sigrun Nestel, Jennifer Schwarz, Kathrin Thedieck, Tanja Voge. TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:30555301. |
we used quantitative proteomics to characterize tgfbr2-deficient cells derived from the mouse telencephalon and identified differential protein expression of the astrocyte proteins gfap (glial fibrillary acidic protein) and mfge8 (milk fat globule-egf factor 8). |
2020-09-29 |
2023-08-13 |
mouse |
Stefan Christopher Weise, Alejandro Villarreal, Stefanie Heidrich, Fariba Dehghanian, Christian Schachtrup, Sigrun Nestel, Jennifer Schwarz, Kathrin Thedieck, Tanja Voge. TGFβ-Signaling and FOXG1-Expression Are a Hallmark of Astrocyte Lineage Diversity in the Murine Ventral and Dorsal Forebrain. Frontiers in cellular neuroscience. vol 12. 2020-09-29. PMID:30555301. |
additionally, lineage tracing revealed that both gfap and mfge8 astrocyte subtypes derived partly from foxg1-expressing neural precursor cells. |
2020-09-29 |
2023-08-13 |
mouse |
Vadim V Tarasov, Andrey A Svistunov, Vladimir N Chubarev, Susanna S Sologova, Polina Mukhortova, Dmitrii Levushkin, Siva G Somasundaram, Cecil E Kirkland, Sergey O Bachurin, Gjumrakch Alie. Alterations of Astrocytes in the Context of Schizophrenic Dementia. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:32116664. |
the levels of the astrocyte markers (gfap, s100b) were increased unevenly in patients with schizophrenia. |
2020-09-28 |
2023-08-13 |
Not clear |
Dipro Bose, Ayan Mondal, Punnag Saha, Diana Kimono, Sutapa Sarkar, Ratanesh K Seth, Patricia Janulewicz, Kimberly Sullivan, Ronnie Horner, Nancy Klimas, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterje. TLR Antagonism by Sparstolonin B Alters Microbial Signature and Modulates Gastrointestinal and Neuronal Inflammation in Gulf War Illness Preclinical Model. Brain sciences. vol 10. issue 8. 2020-09-28. PMID:32784362. |
ssnb significantly decreased astrocyte activation by decreasing colocalization of glial fibrillary acid protein (gfap) and s100 calcium-binding protein b (s100b), a crucial event in neuronal inflammation. |
2020-09-28 |
2023-08-13 |
mouse |
Safiye Çavdar, Yasemin Kuvvet, Ilknur Sur-Erdem, Merve Özgür, Filiz Ona. Relationships between astrocytes and absence epilepsy in rat: An experimental study. Neuroscience letters. vol 712. 2020-09-23. PMID:31560994. |
in the present study we aimed to quantify the number of astrocytes expressing the astrocyte marker glial fibrillary acidic protein (gfap) in the somatosensory cortex (sscx), ventrobasal (vb), centromedial (cm), reticular (trn) and dorsal lateral geniculate (dlgn) nuclei of thalamus in genetic absence epilepsy rats from strasbourg (gaers), wistar albino glaxo rats from rijswijk (wag/rij) and control wistar animals. |
2020-09-23 |
2023-08-13 |
rat |
Safiye Çavdar, Yasemin Kuvvet, Ilknur Sur-Erdem, Merve Özgür, Filiz Ona. Relationships between astrocytes and absence epilepsy in rat: An experimental study. Neuroscience letters. vol 712. 2020-09-23. PMID:31560994. |
these findings demonstrate a discrete difference in both gfap-positive astrocyte populations and gfap protein expression levels between wistar and genetically epileptic strains (gaers and wag/rij). |
2020-09-23 |
2023-08-13 |
rat |
Safiye Çavdar, Yasemin Kuvvet, Ilknur Sur-Erdem, Merve Özgür, Filiz Ona. Relationships between astrocytes and absence epilepsy in rat: An experimental study. Neuroscience letters. vol 712. 2020-09-23. PMID:31560994. |
astrocytes regulate the concentration of glutamate and gaba in the extracellular space in the brain, the difference in the astrocyte population and gfap protein expression in the epileptic strains clearly shows the involvement of astrocytes in the mechanism of absence epilepsy. |
2020-09-23 |
2023-08-13 |
rat |
Fabiana Galland, Marina Seady, Jessica Taday, Soraya Soubhi Smaili, Carlos Alberto Gonçalves, Marina Concli Leit. Astrocyte culture models: Molecular and function characterization of primary culture, immortalized astrocytes and C6 glioma cells. Neurochemistry international. vol 131. 2020-09-03. PMID:31430518. |
gfap, s100b, aqp4 and aldh1l1), although expressing them in less quantities then primary astrocyte cultures. |
2020-09-03 |
2023-08-13 |
Not clear |
Da-Peng Wang, Hang Yin, Qi Lin, Shu-Ping Fang, Jian-Hua Shen, Yi-Fang Wu, Shao-Hua Su, Jian Ha. Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion. Naunyn-Schmiedeberg's archives of pharmacology. vol 392. issue 10. 2020-08-31. PMID:31187188. |
astrocyte activation was examined by immunohistochemical staining and western blotting for glial fibrillary acid protein (gfap), while expression levels of the pro-inflammatory cytokine-tumor necrosis factor alpha (tnf-α) and interleukin 1 beta (il-1β), the apoptosis effector cysteinyl aspartate specific proteinase-3 (caspase-3), and the neuroprotectant brain-derived neurotrophic factor (bdnf) and the trkb receptor were estimated by western blotting. |
2020-08-31 |
2023-08-13 |
rat |