| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isidro Ferrer, Pol Andrés-Benito, Maria Victoria Zelaya, Maria Elena Erro Aguirre, Margarita Carmona, Karina Ausín, Mercedes Lachén-Montes, Joaquín Fernández-Irigoyen, Enrique Santamaría, José Antonio Del Ri. Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy. Acta neuropathologica. vol 139. issue 4. 2021-05-17. PMID:31907603. |
in ggt cases linked to mapt p301t mutation, astrocyte markers gfap, aldh1l1, ykl40 mrna and protein, gja1 mrna, and aq4 protein are significantly increased; glutamate transporter glt1 (eaat2) and glucose transporter (slc2a1) decreased; mitochondrial pyruvate carrier 1 (mpc1) increased, and mitochondrial uncoupling protein 5 (ucp5) almost absent in gais in frontal cortex (fc). |
2021-05-17 |
2023-08-13 |
mouse |
| Lina Zhao, Xianyu Zhang, Chunhai Zhan. Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model Mediators of inflammation. vol 2020. 2021-05-17. PMID:32351321. |
methimazole inhibits the expression of gfap and the migration of astrocyte in scratched wound model astrocytes respond to central nervous system (cns) insults with varieties of changes, such as cellular hypertrophy, migration, proliferation, scar formation, and upregulation of glial fibrillary acidic protein (gfap) expression. |
2021-05-17 |
2023-08-13 |
Not clear |
| Nagla A El-Sherbeeny, Afaf T Ibrahiem, Howaida S Ali, Noha E Farag, Eman A Toraih, Sawsan A Zaiton. Carbamazepine conquers spinal GAP43 deficiency and sciatic Nav1.5 upregulation in diabetic mice: novel mechanisms in alleviating allodynia and hyperalgesia. Archives of pharmacal research. vol 43. issue 7. 2021-05-17. PMID:32676893. |
the spinal cords were evaluated for synaptic plasticity (growth associated protein-43, gap43), microglia cell expression (by cd11b) and astrocyte expression (glial fibrillary acidic protein, gfap). |
2021-05-17 |
2023-08-13 |
mouse |
| Manoj K Gottipati, Anthony R D'Amato, Alexis M Ziemba, Phillip G Popovich, Ryan J Gilber. TGFβ3 is neuroprotective and alleviates the neurotoxic response induced by aligned poly-l-lactic acid fibers on naïve and activated primary astrocytes. Acta biomaterialia. vol 117. 2021-05-14. PMID:33035696. |
gene expression analysis of the pan-reactive astrocyte makers (gfap, lcn2, serpina3), a1 specific markers (h2-d1, serping1), and a2 specific makers (emp1, s100a10) was done using quantitative polymerase chain reaction (qpcr). |
2021-05-14 |
2023-08-13 |
Not clear |
| David Pamies, Chiara Sartori, Domitille Schvartz, Víctor González-Ruiz, Luc Pellerin, Carolina Nunes, Denise Tavel, Vanille Maillard, Julien Boccard, Serge Rudaz, Jean-Charles Sanchez, Marie-Gabrielle Zuric. Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro. International journal of molecular sciences. vol 22. issue 8. 2021-05-12. PMID:33920048. |
strong modifications of astrocyte cytoskeleton were observed, including a glial fibrillary acidic protein (gfap) decrease. |
2021-05-12 |
2023-08-13 |
human |
| Antonio Cibelli, Sandra Veronica Lopez-Quintero, Sean Mccutcheon, Eliana Scemes, David C Spray, Randy F Stout, Sylvia O Suadicani, Mia M Thi, Marcia Urban-Maldonad. Generation and Characterization of Immortalized Mouse Cortical Astrocytes From Wildtype and Connexin43 Knockout Mice. Frontiers in cellular neuroscience. vol 15. 2021-05-11. PMID:33790744. |
the mrna levels of the astrocyte biomarkers aldehyde dehydrogenase 1l1 (aldh1l1), glutamine synthetase (gs) and glial fibrillary acidic protein (gfap) remained relatively constant during successive passages. |
2021-05-11 |
2023-08-13 |
mouse |
| Carollina Da Ré, Jéssica Maria Souza, Fernanda Fróes, Jéssica Taday, João Paulo Dos Santos, Letícia Rodrigues, Patrícia Sesterheim, Carlos Alberto Gonçalves, Marina Concli Leit. Neuroinflammation induced by lipopolysaccharide leads to memory impairment and alterations in hippocampal leptin signaling. Behavioural brain research. vol 379. 2021-05-03. PMID:31734263. |
neuroinflammation was characterized in the lps group by an increase in concentration of il-1β, cox-2 and tlr4 in the hippocampus as well as glial fibrillary acidic protein (gfap), indicating an astrocyte commitment. |
2021-05-03 |
2023-08-13 |
rat |
| Erratum in: Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve. Investigative ophthalmology & visual science. vol 61. issue 14. 2021-05-03. PMID:33355604. |
erratum in: pressure-induced changes in astrocyte gfap, actin, and nuclear morphology in mouse optic nerve. |
2021-05-03 |
2023-08-13 |
mouse |
| Haixia Du, Yu He, Yuanjiang Pan, Mengdi Zhao, Zhiwei Li, Yu Wang, Jiehong Yang, Haitong Wa. Danhong Injection Attenuates Cerebral Ischemia-Reperfusion Injury in Rats Through the Suppression of the Neuroinflammation. Frontiers in pharmacology. vol 12. 2021-05-02. PMID:33927611. |
immunohistochemical staining results also revealed that dhi dose-dependently diminished the protein expressions of icam-1 and cox-2, and suppressed the activation of microglia (ionized calcium-binding adapter molecule 1, iba-1) and astrocyte (glial fibrillary acidic protein, gfap) in the cerebral cortex. |
2021-05-02 |
2023-08-13 |
rat |
| Hyunha Kim, Ji Seon Seo, Seo-Yeon Lee, Ki-Tae Ha, Byung Tae Choi, Yong-Il Shin, Young Ju Yun, Hwa Kyoung Shi. AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32201254. |
aim2 immunoreactivity of the psci group was primarily co-localized with iba-1 (microglial marker) and cd31 (endothelial cell marker) immunoreactivities but not neun (neuronal marker) and gfap (astrocyte marker) immunoreactivities, suggesting that microglia or endothelial cell-induced aim2 production mediated psci pathogenesis. |
2021-04-27 |
2023-08-13 |
mouse |
| Ning Zhang, Chunhong Liu, Ruiyan Zhang, Li Jin, Xiaohan Yin, Xuexing Zheng, Hans-Christian Siebert, Yubao Li, Zhengping Wang, Gabriele Loers, Athanasios K Petridi. Amelioration of clinical course and demyelination in the cuprizone mouse model in relation to ketogenic diet. Food & function. vol 11. issue 6. 2021-04-26. PMID:32539054. |
concomitant, the protein expressions of glial fibrillary acidic protein (gfap, an astrocyte marker), ionized calcium-binding adaptor molecule 1 (iba-1, a microglial marker), cd68 (an activated microglia marker) and cd16/32 (a m1 microglial marker) were down-regulated, while the expression of oligodendrocyte lineage transcription factor 2 (olig2, an oligodendrocyte precursor cells marker) was up-regulated by the kd treatment. |
2021-04-26 |
2023-08-13 |
mouse |
| Mafalda Campeão, Luciana Fernandes, Inês R Pita, Cristina Lemos, Syed F Ali, Félix Carvalho, Paulo Rodrigues-Santos, Carlos A Fontes-Ribeiro, Edna Soares, Sofia D Viana, Frederico C Pereir. Acute MDPV Binge Paradigm on Mice Emotional Behavior and Glial Signature. Pharmaceuticals (Basel, Switzerland). vol 14. issue 3. 2021-04-13. PMID:33809599. |
additionally, striatal th (meth neurotoxicity hallmark), iba-1 (microglia), gfap (astrocyte), rage, and tlr2/4/7 (immune modulators) protein densities remained unchanged after mdpv-exposure. |
2021-04-13 |
2023-08-13 |
mouse |
| Yukie Hirahara, Taketoshi Wakabayashi, Taro Koike, Keizo Gamo, Hisao Yamad. Change in phospholipid species of retinal layer in traumatic optic neuropathy model. Journal of neuroscience research. vol 98. issue 2. 2021-04-05. PMID:31385342. |
reactive astrocyte accumulation, glia scar formation, and demyelination were observed in the injured optic nerve area, while rgc cell death, astrocyte accumulation, and glial fibrillary acidic protein (gfap) positive müller cell increases were detected in the retinal layer. |
2021-04-05 |
2023-08-13 |
mouse |
| Michael Brenner, Albee Messin. Regulation of GFAP Expression. ASN neuro. vol 13. 2021-04-01. PMID:33601918. |
expression of the gfap gene has attracted considerable attention because its onset is a marker for astrocyte development, its upregulation is a marker for reactive gliosis, and its predominance in astrocytes provides a tool for their genetic manipulation. |
2021-04-01 |
2023-08-13 |
Not clear |
| Michael Brenner, Albee Messin. Regulation of GFAP Expression. ASN neuro. vol 13. 2021-04-01. PMID:33601918. |
the complexity involved in regulating the expression of this intermediate filament protein suggests that gfap function may vary among both astrocyte subtypes and other gfap-expressing cells, as well as during development and in response to perturbations. |
2021-04-01 |
2023-08-13 |
Not clear |
| Yik Tung Tracy Ling, Mary E Pease, Joan L Jefferys, Elizabeth C Kimball, Harry A Quigley, Thao D Nguye. Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve. Investigative ophthalmology & visual science. vol 61. issue 11. 2021-03-31. PMID:32910133. |
pressure-induced changes in astrocyte gfap, actin, and nuclear morphology in mouse optic nerve. |
2021-03-31 |
2023-08-13 |
mouse |
| Carlos Vicente-Gutierrez, Juan P Bolaño. An Bio-protocol. vol 10. issue 6. 2021-03-21. PMID:33659524. |
here we propose an approach to specifically assess mros abundance in astrocytes that combines i) a targeting strategy based on the use of adeno-associated virus (aav) vectors expressing the green fluorescent protein (gfp) under an astrocyte (glial fibrillary acidic protein or gfap) promoter, along with, ii) a robust and widely extended protocol for the measurement of mros by flow cytometry using commercial probes. |
2021-03-21 |
2023-08-13 |
Not clear |
| Lidija Radenovic, Marija Nenadic, Marzena Ułamek-Kozioł, Sławomir Januszewski, Stanisław J Czuczwar, Pavle R Andjus, Ryszard Plut. Heterogeneity in brain distribution of activated microglia and astrocytes in a rat ischemic model of Alzheimer's disease after 2 years of survival. Aging. vol 12. issue 12. 2021-03-08. PMID:32501292. |
for the visualization of the cellular inflammatory reaction microglial marker iba1 and astrocyte marker gfap were used. |
2021-03-08 |
2023-08-13 |
rat |
| Samantha L Hodges, Suzanne O Nolan, Lindsay A Tomac, Ilyasah D A Muhammad, Matthew S Binder, Joseph H Taube, Joaquin N Lug. Lipopolysaccharide-induced inflammation leads to acute elevations in pro-inflammatory cytokine expression in a mouse model of Fragile X syndrome. Physiology & behavior. vol 215. 2021-03-04. PMID:31838149. |
there were no differences in hippocampal protein expression between genotypes in microglia (iba1) or astrocyte (gfap) reactivity. |
2021-03-04 |
2023-08-13 |
mouse |
| Michelle N Sullivan, Samuel A Brill, Lisa M Mangus, Yea Ji Jeong, Clarisse V Solis, Audrey C Knight, Carlo Colantuoni, Gizem Keceli, Nazareno Paolocci, Suzanne E Queen, Joseph L Mankowsk. Upregulation of Superoxide Dismutase 2 by Astrocytes in the SIV/Macaque Model of HIV-Associated Neurologic Disease. Journal of neuropathology and experimental neurology. vol 79. issue 9. 2021-03-01. PMID:32783052. |
double immunofluorescence labeling illustrated that sod2 primarily colocalized with astrocyte marker glial fibrillary acidic protein (gfap) in siv-infected animals. |
2021-03-01 |
2023-08-13 |
monkey |