| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Humpel, C Wei. Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices. Implication in Alzheimer's disease? Journal of neural transmission. Supplementum. issue 62. 2003-01-10. PMID:12456068. |
nerve growth factor (ngf) is a potent growth factor for cholinergic neurons. |
2003-01-10 |
2023-08-12 |
Not clear |
| C Humpel, C Wei. Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices. Implication in Alzheimer's disease? Journal of neural transmission. Supplementum. issue 62. 2003-01-10. PMID:12456068. |
the aim of the present study was to investigate if ngf affects cholinergic neurons of the basal nucleus of meynert (nbm) in organotypic brain slices. |
2003-01-10 |
2023-08-12 |
Not clear |
| C Humpel, C Wei. Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices. Implication in Alzheimer's disease? Journal of neural transmission. Supplementum. issue 62. 2003-01-10. PMID:12456068. |
in single nbm slices cholinergic neurons rapidly degenerated when incubated without ngf. |
2003-01-10 |
2023-08-12 |
Not clear |
| C Humpel, C Wei. Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices. Implication in Alzheimer's disease? Journal of neural transmission. Supplementum. issue 62. 2003-01-10. PMID:12456068. |
in conclusion, ngf is the most potent growth factor for cholinergic neurons and is a promising candidate for treating alzheimers disease, however, the delivery of ngf to the brain must the solved. |
2003-01-10 |
2023-08-12 |
Not clear |
| Donald P Pizzo, Jürgen Winkler, Ibrahim Sidiqi, Jerene J Waite, Leon J Tha. Modulation of sensory inputs and ectopic presence of Schwann cells depend upon the route and duration of nerve growth factor administration. Experimental neurology. vol 178. issue 1. 2003-01-08. PMID:12460611. |
nerve growth factor (ngf) ameliorates deficits in models of cholinergic hypofunction. |
2003-01-08 |
2023-08-12 |
rat |
| Donald P Pizzo, Jürgen Winkler, Ibrahim Sidiqi, Jerene J Waite, Leon J Tha. Modulation of sensory inputs and ectopic presence of Schwann cells depend upon the route and duration of nerve growth factor administration. Experimental neurology. vol 178. issue 1. 2003-01-08. PMID:12460611. |
in order to maintain efficacy on the cholinergic basal forebrain (cbf) and minimize these detrimental effects, intraparenchymal ngf infusion was compared with icv administration to assess morphological and functional measures. |
2003-01-08 |
2023-08-12 |
rat |
| R Miller, M A King, M B Heaton, D W Walke. The effects of chronic ethanol consumption on neurotrophins and their receptors in the rat hippocampus and basal forebrain. Brain research. vol 950. issue 1-2. 2002-12-23. PMID:12231238. |
cet effects on basal forebrain trka may reflect impaired ngf signaling that could compromise septohippocampal synaptic connections, cholinergic differentiation, and emergent functional abilities dependent on these properties. |
2002-12-23 |
2023-08-12 |
rat |
| Yasuhiro Ind. Genetics of congenital insensitivity to pain with anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV. Clinical, biological and molecular aspects of mutations in TRKA(NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 12 Suppl 1. 2002-12-20. PMID:12102460. |
nerve growth factor (ngf) supports the survival of nociceptive sensory and autonomic sympathetic neurons as well as cholinergic neurons of the basal forebrain. |
2002-12-20 |
2023-08-12 |
human |
| G Calamandrei, L Aloe, J Hajek, M Zappell. Developmental profile of serum nerve growth factor levels in Rett complex. Annali dell'Istituto superiore di sanita. vol 37. issue 4. 2002-12-13. PMID:12046231. |
converging evidence shows that the brain levels of nerve growth factor (ngf), a neurotrophin regulating the development and functioning of central cholinergic neurons, are decreased in rs girls. |
2002-12-13 |
2023-08-12 |
human |
| Simona Capsoni, Sabina Giannotta, Antonino Cattane. Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies. Molecular and cellular neurosciences. vol 21. issue 1. 2002-11-19. PMID:12359148. |
we recently described that the brain of aged transgenic mice expressing anti-nerve growth factor (ngf) antibodies (ad11 mice) show a dramatic neurodegenerative phenotype, reminiscent of ad, which includes neuronal loss, cholinergic deficit, and tau hyperphosphorylation, associated with neurofibrillary pathology. |
2002-11-19 |
2023-08-12 |
mouse |
| Simona Capsoni, Sabina Giannotta, Antonino Cattane. Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 19. 2002-10-28. PMID:12205295. |
in this article, we examine whether and how the progressive neurodegenerative phenotype of ad11 mice could be prevented or ameliorated by pharmacological treatments with ngf or the cholinergic agonist galantamine, at a relatively early phase of alzheimer's disease-like neurodegeneration. |
2002-10-28 |
2023-08-12 |
mouse |
| Marco Fiore, Jakob Korf, Alessia Antonelli, Lucia Talamini, Luigi Alo. Long-lasting effects of prenatal MAM treatment on water maze performance in rats: associations with altered brain development and neurotrophin levels. Neurotoxicology and teratology. vol 24. issue 2. 2002-08-27. PMID:11943506. |
these behavioral changes were associated with significant changes in brain nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf), reduced choline acetyltransferase (chat) immunoreactivity in forebrain cholinergic neurons and loss of neuropeptide y (npy) immunodistribution in cells of the entorhinal cortex. |
2002-08-27 |
2023-08-12 |
rat |
| S D Skape. Nerve growth factor: a neurokine orchestrating neuroimmune-endocrine functions. Molecular neurobiology. vol 24. issue 1-3. 2002-07-24. PMID:11831552. |
nerve growth factor (ngf) is widely recognized as a target-derived factor responsible for the survival and maintenance of the phenotype of specific subsets of peripheral neurons and basal forebrain cholinergic nuclei during development and maturation. |
2002-07-24 |
2023-08-12 |
Not clear |
| Grazyna Niewiadomska, Sebastian Komorowski, Marta Baksalerska-Pazer. Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of NGF. Neurobiology of aging. vol 23. issue 4. 2002-07-08. PMID:12009509. |
amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of ngf. |
2002-07-08 |
2023-08-12 |
rat |
| Grazyna Niewiadomska, Sebastian Komorowski, Marta Baksalerska-Pazer. Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of NGF. Neurobiology of aging. vol 23. issue 4. 2002-07-08. PMID:12009509. |
the present study was designed to examine whether ngf-induced improvement in morphology of senile basal forebrain cholinergic neurons persist after discontinuation of ngf treatment. |
2002-07-08 |
2023-08-12 |
rat |
| Grazyna Niewiadomska, Sebastian Komorowski, Marta Baksalerska-Pazer. Amelioration of cholinergic neurons dysfunction in aged rats depends on the continuous supply of NGF. Neurobiology of aging. vol 23. issue 4. 2002-07-08. PMID:12009509. |
ngf may be beneficial in enhancing cholinergic neurochemical parameters, but the protective effects seem to be dependent on the continuous supply of ngf. |
2002-07-08 |
2023-08-12 |
rat |
| Claude Brodski, Andreas Schaubmar, Georg Dechan. Opposing functions of GDNF and NGF in the development of cholinergic and noradrenergic sympathetic neurons. Molecular and cellular neurosciences. vol 19. issue 4. 2002-06-24. PMID:11988020. |
opposing functions of gdnf and ngf in the development of cholinergic and noradrenergic sympathetic neurons. |
2002-06-24 |
2023-08-12 |
Not clear |
| Claude Brodski, Andreas Schaubmar, Georg Dechan. Opposing functions of GDNF and NGF in the development of cholinergic and noradrenergic sympathetic neurons. Molecular and cellular neurosciences. vol 19. issue 4. 2002-06-24. PMID:11988020. |
we conclude that cholinergic properties can be regulated by neurotrophic factors from three different protein families, whereas noradrenergic properties are promoted by ngf. |
2002-06-24 |
2023-08-12 |
Not clear |
| Beth Adams, Liezanne Vaccarella, Margaret Fahnestock, Ronald J Racin. The cholinergic system modulates kindling and kindling-induced mossy fiber sprouting. Synapse (New York, N.Y.). vol 44. issue 3. 2002-06-20. PMID:11954044. |
the purpose of the present study was to investigate whether these ngf effects were mediated via the cholinergic system. |
2002-06-20 |
2023-08-12 |
rat |
| Beth Adams, Liezanne Vaccarella, Margaret Fahnestock, Ronald J Racin. The cholinergic system modulates kindling and kindling-induced mossy fiber sprouting. Synapse (New York, N.Y.). vol 44. issue 3. 2002-06-20. PMID:11954044. |
moreover, these data provide support for the hypothesis that ngf infusions may mediate kindling and kindling-induced mossy fiber sprouting via regulation of the cholinergic system. |
2002-06-20 |
2023-08-12 |
rat |