| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U E Lang, M Mühlbacher, M B Hesselink, W Zajaczkowski, W Danysz, H Danker-Hopfe, R Hellwe. No nerve growth factor response to treatment with memantine in adult rats. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 2. 2004-05-19. PMID:14767721. |
nerve growth factor (ngf) is the most widely examined neurotrophin in the experimental models of alzheimer's disease (ad) and has been shown to prevent the retrograde degeneration of cholinergic neurons. |
2004-05-19 |
2023-08-12 |
rat |
| Hai Wu, Wilma J Friedman, Cheryl F Dreyfu. Differential regulation of neurotrophin expression in basal forebrain astrocytes by neuronal signals. Journal of neuroscience research. vol 76. issue 1. 2004-05-04. PMID:15048931. |
nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), and neurotrophin-3 (nt3) promote the function and/or survival of basal forebrain (bf) cholinergic neurons in vivo and in culture. |
2004-05-04 |
2023-08-12 |
Not clear |
| Elliott J Mufson, Stephen D Ginsberg, Milos D Ikonomovic, Steven T DeKosk. Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction. Journal of chemical neuroanatomy. vol 26. issue 4. 2004-04-02. PMID:14729126. |
the human cbf displays a continuum of large cells that contain various cholinergic markers, nerve growth factor (ngf) and its cognate receptors, calbindin, glutamate receptors, and the estrogen receptors, eralpha and erbeta. |
2004-04-02 |
2023-08-12 |
human |
| Neal Prakash, Susana Cohen-Cory, Silke Penschuck, Ron D Frosti. Basal forebrain cholinergic system is involved in rapid nerve growth factor (NGF)-induced plasticity in the barrel cortex of adult rats. Journal of neurophysiology. vol 91. issue 1. 2004-03-01. PMID:14507983. |
basal forebrain cholinergic system is involved in rapid nerve growth factor (ngf)-induced plasticity in the barrel cortex of adult rats. |
2004-03-01 |
2023-08-12 |
rat |
| Neal Prakash, Susana Cohen-Cory, Silke Penschuck, Ron D Frosti. Basal forebrain cholinergic system is involved in rapid nerve growth factor (NGF)-induced plasticity in the barrel cortex of adult rats. Journal of neurophysiology. vol 91. issue 1. 2004-03-01. PMID:14507983. |
these results, taken together with our previously reported imaging results that demonstrated that agonists of the cholinergic system (particularly nicotine) showed transient ngf-like augmentations of a wfr, implicate the bfcs cortical projections as necessary for ngf's rapid plasticity in the adult rat somatosensory cortex. |
2004-03-01 |
2023-08-12 |
rat |
| Francesco Angelucci, Aleksander A Mathé, Luigi Alo. Neurotrophic factors and CNS disorders: findings in rodent models of depression and schizophrenia. Progress in brain research. vol 146. 2004-02-11. PMID:14699963. |
nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) are proteins involved in neuronal survival and plasticity of dopaminergic, cholinergic and serotonergic neurons in the central nervous system (cns). |
2004-02-11 |
2023-08-12 |
rat |
| Grazyna Niewiadomska, Marta Baksalerska-Pazer. Age-dependent changes in axonal transport and cellular distribution of Tau 1 in the rat basal forebrain neurons. Neuroreport. vol 14. issue 13. 2004-01-14. PMID:14512841. |
basal forebrain (bf) cholinergic neurons are prone to degeneration due to age-dependent impairment of uptake and retrograde axonal transport of ngf. |
2004-01-14 |
2023-08-12 |
rat |
| Judith P Golden, Jeffrey Milbrandt, Eugene M Johnso. Neurturin and persephin promote the survival of embryonic basal forebrain cholinergic neurons in vitro. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637114. |
we have now found that neurturin (nrtn) and persephin (pspn) also promote the survival of basal forebrain neurons including both cholinergic neurons and a population of non-cholinergic neurons with an efficacy comparable to ngf. |
2004-01-05 |
2023-08-12 |
rat |
| Sita von Richthofen, Undine E Lang, Rainer Hellwe. Effects of different kinds of acute stress on nerve growth factor content in rat brain. Brain research. vol 987. issue 2. 2003-12-12. PMID:14499965. |
nerve growth factor (ngf) has several effects on the central nervous system; on the one hand ngf fosters survival and function of cholinergic neurons of the basal forebrain, on the other hand this protein is implicated in the stress response of the hypothalamic-pituitary-adrenocortical axis (hpaa). |
2003-12-12 |
2023-08-12 |
rat |
| Shivanand P Lad, Kenneth E Neet, Elliott J Mufso. Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Current drug targets. CNS and neurological disorders. vol 2. issue 5. 2003-11-19. PMID:14529363. |
this interest is based on the observation that cholinergic basal forebrain (cbf) neurons which provide the major source of cholinergic innervation to the cerebral cortex and hippocampus undergo selective and severe degeneration in advanced ad and that these neurons are dependent upon ngf and its receptors for their survival. |
2003-11-19 |
2023-08-12 |
Not clear |
| Shivanand P Lad, Kenneth E Neet, Elliott J Mufso. Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Current drug targets. CNS and neurological disorders. vol 2. issue 5. 2003-11-19. PMID:14529363. |
recent findings indicate an early defect in ngf receptor expression in cbf neurons; therefore treatments aimed at facilitating ngf actions may prove highly beneficial in counteracting the cholinergic dysfunction found in end-stage ad and attenuating the rate of degeneration of these cholinergic neurons. |
2003-11-19 |
2023-08-12 |
Not clear |
| H Shimode, A Ueki, Y Morit. Nerve growth factor attenuates hippocampal cholinergic deficits and operant learning impairment in rats with entorhinal cortex lesions. Behavioural pharmacology. vol 14. issue 3. 2003-10-14. PMID:12799519. |
in the present study we investigated whether continuous intraventricular nerve growth factor (ngf) infusion could ameliorate hippocampal cholinergic deficits and learning impairment following entorhinal cortex lesions. |
2003-10-14 |
2023-08-12 |
rat |
| H Shimode, A Ueki, Y Morit. Nerve growth factor attenuates hippocampal cholinergic deficits and operant learning impairment in rats with entorhinal cortex lesions. Behavioural pharmacology. vol 14. issue 3. 2003-10-14. PMID:12799519. |
these results suggest that enhanced performance of the learning task with ngf treatment was related to improved hippocampal cholinergic function: specifically, increased cholinergic neurotransmission resulting from ngf effects on cholinergic neurons and presynaptic terminals. |
2003-10-14 |
2023-08-12 |
rat |
| C A Gericke, U E Lang, T Steckler, G Schulze, M Bajbouj, R Hellwe. Nerve growth factor response to excitotoxic lesion of the cholinergic basal forebrain is slightly impaired in aged rats. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 6. 2003-09-26. PMID:12768358. |
nerve growth factor (ngf) promotes survival and function of basal forebrain cholinergic neurons. |
2003-09-26 |
2023-08-12 |
rat |
| C A Gericke, U E Lang, T Steckler, G Schulze, M Bajbouj, R Hellwe. Nerve growth factor response to excitotoxic lesion of the cholinergic basal forebrain is slightly impaired in aged rats. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 6. 2003-09-26. PMID:12768358. |
these results indicate that the compensatory ngf increase in the posterior cortex after partial cholinergic lesion of the basal forebrain is slightly impaired in old age. |
2003-09-26 |
2023-08-12 |
rat |
| A Cadete-Leite, P A Pereira, M D Madeira, M M Paula-Barbos. Nerve growth factor prevents cell death and induces hypertrophy of basal forebrain cholinergic neurons in rats withdrawn from prolonged ethanol intake. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831864. |
it is widely accepted that nerve growth factor (ngf) signals the neurons of the brain cholinergic system, including those of the medial septum/vertical limb of the diagonal band of broca (ms/vdb) nuclei, from which the septohippocampal projection arises. |
2003-09-05 |
2023-08-12 |
rat |
| A Cadete-Leite, P A Pereira, M D Madeira, M M Paula-Barbos. Nerve growth factor prevents cell death and induces hypertrophy of basal forebrain cholinergic neurons in rats withdrawn from prolonged ethanol intake. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831864. |
because neurons in these nuclei are vulnerable to ethanol consumption and withdrawal we thought of interest to investigate, in withdrawn rats previously submitted to a prolonged period of ethanol intake, the effects of intraventricular delivery of ngf upon the ms/vdb cholinergic neurons. |
2003-09-05 |
2023-08-12 |
rat |
| A Cadete-Leite, P A Pereira, M D Madeira, M M Paula-Barbos. Nerve growth factor prevents cell death and induces hypertrophy of basal forebrain cholinergic neurons in rats withdrawn from prolonged ethanol intake. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831864. |
ngf treatment prevented the withdrawal-associated loss, and induced hypertrophy, of cholinergic neurons. |
2003-09-05 |
2023-08-12 |
rat |
| A Cadete-Leite, P A Pereira, M D Madeira, M M Paula-Barbos. Nerve growth factor prevents cell death and induces hypertrophy of basal forebrain cholinergic neurons in rats withdrawn from prolonged ethanol intake. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831864. |
these findings show that exogenous ngf protects the phenotype and prevents the withdrawal-induced degeneration of cholinergic neurons in the ms/vdb. |
2003-09-05 |
2023-08-12 |
rat |
| A Cadete-Leite, P A Pereira, M D Madeira, M M Paula-Barbos. Nerve growth factor prevents cell death and induces hypertrophy of basal forebrain cholinergic neurons in rats withdrawn from prolonged ethanol intake. Neuroscience. vol 119. issue 4. 2003-09-05. PMID:12831864. |
these effects might be due to the trophic action of ngf upon the basal forebrain cholinergic neurons, including the hippocampal fiber network that conveys this neurotrophin retrogradely to the ms/vdb, and/or upon their targets, that is, the hippocampal formation neurons. |
2003-09-05 |
2023-08-12 |
rat |