| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Serrano-Sánchez, M A Robinson-Agramonte, L Lorigados-Pedre, I Díaz-Armesto, M E González-Fraguela, A J Dorta-Contrera. [Endogenous nerve growth factor in patients with Alzheimer s disease]. Revista de neurologia. vol 32. issue 9. 2003-07-28. PMID:11424032. |
initially it was postulated that alterations in the expression of ngf within its production sites may be responsible for the consistent atrophy and loss of cholinergic basal forebrain neurons in dementing illness such as alzheimer s disease (ad). |
2003-07-28 |
2023-08-12 |
Not clear |
| Paola Tirassa, Viviana Triaca, Tiziana Amendola, Marco Fiore, Luigi Alo. EGF and NGF injected into the brain of old mice enhance BDNF and ChAT in proliferating subventricular zone. Journal of neuroscience research. vol 72. issue 5. 2003-07-16. PMID:12749020. |
enhanced numbers of svz cells expressing proliferative markers were also discovered in egf + ngf treated mice and some of these cells expressed cholinergic markers, as demonstrated by double immunostaining. |
2003-07-16 |
2023-08-12 |
mouse |
| Nikolai V Lukoyanov, Pedro A Pereira, Manuel M Paula-Barbosa, António Cadete-Leit. Nerve growth factor improves spatial learning and restores hippocampal cholinergic fibers in rats withdrawn from chronic treatment with ethanol. Experimental brain research. vol 148. issue 1. 2003-06-18. PMID:12478399. |
we hypothesized that exogenous supply of nerve growth factor (ngf), known to serve as a trophic substance for septal cholinergic neurons, can revert the ethanol-induced changes in the septohippocampal cholinergic system. |
2003-06-18 |
2023-08-12 |
rat |
| Nikolai V Lukoyanov, Pedro A Pereira, Manuel M Paula-Barbosa, António Cadete-Leit. Nerve growth factor improves spatial learning and restores hippocampal cholinergic fibers in rats withdrawn from chronic treatment with ethanol. Experimental brain research. vol 148. issue 1. 2003-06-18. PMID:12478399. |
these data provide support to the notion that ngf is capable of ameliorating memory deficits and restoring septohippocampal cholinergic projections following chronic treatment with ethanol. |
2003-06-18 |
2023-08-12 |
rat |
| B Madziar, M Tomaszewicz, A Matecki, H Bielarczyk, A Szutowic. Interactions between p75 and TrkA receptors in differentiation and vulnerability of SN56 cholinergic cells to beta-amyloid. Neurochemical research. vol 28. issue 3-4. 2003-06-18. PMID:12675131. |
ngf modifies cholinergic neurons through its low-p75 and high affinity-trka receptors. |
2003-06-18 |
2023-08-12 |
Not clear |
| Vinay Parikh, Denise R Evans, Mohammad M Khan, Sahebarao P Mahadi. Nerve growth factor in never-medicated first-episode psychotic and medicated chronic schizophrenic patients: possible implications for treatment outcome. Schizophrenia research. vol 60. issue 2-3. 2003-06-11. PMID:12591576. |
nerve growth factor (ngf) has been found to play a crucial role in the neuroplasticity of predominantly cholinergic neurons in brain development, and neuronal survival following brain injury, which reflect in cognitive performance. |
2003-06-11 |
2023-08-12 |
human |
| Dave Albeck, Michael H Mesches, Sonya Juthberg, Michael Browning, Paula C Bickford, Gregory M Rose, A-Ch Granhol. Exogenous NGF restores endogenous NGF distribution in the brain of the cognitively impaired aged rat. Brain research. vol 967. issue 1-2. 2003-06-05. PMID:12650994. |
alzheimer's disease and normal aging may impair retrograde transport of nerve growth factor (ngf) from cortical areas to basal forebrain cholinergic neurons. |
2003-06-05 |
2023-08-12 |
rat |
| Julio J Ramirez, Jennifer L Caldwell, Melanie Majure, David R Wessner, Ronald L Klein, Edwin M Meyer, Michael A Kin. Adeno-associated virus vector expressing nerve growth factor enhances cholinergic axonal sprouting after cortical injury in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 7. 2003-05-30. PMID:12684466. |
nerve growth factor (ngf) is known to promote both the survival of cholinergic neurons after injury and the regeneration of damaged cholinergic axons. |
2003-05-30 |
2023-08-12 |
rat |
| Julio J Ramirez, Jennifer L Caldwell, Melanie Majure, David R Wessner, Ronald L Klein, Edwin M Meyer, Michael A Kin. Adeno-associated virus vector expressing nerve growth factor enhances cholinergic axonal sprouting after cortical injury in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 7. 2003-05-30. PMID:12684466. |
recent evidence has implicated ngf in the regulation of cholinergic axonal sprouting by intact neurons projecting to the hippocampus of rats, sustaining a lesion of the entorhinal cortex. |
2003-05-30 |
2023-08-12 |
rat |
| Julio J Ramirez, Jennifer L Caldwell, Melanie Majure, David R Wessner, Ronald L Klein, Edwin M Meyer, Michael A Kin. Adeno-associated virus vector expressing nerve growth factor enhances cholinergic axonal sprouting after cortical injury in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 7. 2003-05-30. PMID:12684466. |
we explored the possibility that ngf may regulate this lesion-induced cholinergic sprouting by injecting recombinant adeno-associated virus (raav) vector expressing ngf and green fluorescent protein (gfp) into the dentate gyrus of rats that were subsequently given unilateral entorhinal lesions. |
2003-05-30 |
2023-08-12 |
rat |
| Julio J Ramirez, Jennifer L Caldwell, Melanie Majure, David R Wessner, Ronald L Klein, Edwin M Meyer, Michael A Kin. Adeno-associated virus vector expressing nerve growth factor enhances cholinergic axonal sprouting after cortical injury in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 7. 2003-05-30. PMID:12684466. |
optical densitometric analyses revealed a significant increase in acetylcholinesterase label (a marker for cholinergic septodentate sprouting) in the ipsilateral outer molecular layer of the dentate gyrus in rats injected with raav vector expressing ngf. |
2003-05-30 |
2023-08-12 |
rat |
| Christopher L Hunter, Ole Isacson, Matthew Nelson, Heather Bimonte-Nelson, Hyemyung Seo, Ling Lin, Kerstin Ford, Mark S Kindy, Ann-Charlotte Granhol. Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome. Neuroscience research. vol 45. issue 4. 2003-05-23. PMID:12657457. |
these findings demonstrate that elevated app and decreased ngf levels in limbic areas correlate with the progressive memory decline and cholinergic degeneration seen in middle-aged trisomic mice. |
2003-05-23 |
2023-08-12 |
mouse |
| b' Francesco Angelucci, Luigi Aloe, Patricia Jim\\xc3\\xa9nez-Vasquez, Aleksander A Math\\xc3\\xa. Electroconvulsive stimuli alter nerve growth factor but not brain-derived neurotrophic factor concentrations in brains of a rat model of depression. Neuropeptides. vol 37. issue 1. 2003-05-15. PMID:12637036.' |
nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) are proteins involved in neuronal survival and plasticity of dopaminergic, cholinergic and serotonergic neurons in the central nervous system (cns). |
2003-05-15 |
2023-08-12 |
rat |
| Heather A Bimonte-Nelson, Christopher L Hunter, Matthew E Nelson, Ann-Charlotte E Granhol. Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome. Behavioural brain research. vol 139. issue 1-2. 2003-05-02. PMID:12642175. |
we evaluated memory as well as brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) protein levels in basal forebrain, frontal cortex, hippocampus, and striatum in ts65dn mice at the age when cholinergic degeneration is first observed, and compared values to normosomic controls. |
2003-05-02 |
2023-08-12 |
mouse |
| Ronald L Klein, Mary E Hamby, Christopher F Sonntag, William J Millard, Michael A King, Edwin M Meye. Measurements of vector-derived neurotrophic factor and green fluorescent protein levels in the brain. Methods (San Diego, Calif.). vol 28. issue 2. 2003-04-23. PMID:12413428. |
injections of either cba-nerve growth factor (ngf)-wpre or cba-glial cell line-derived neutrotrophic factor-wpre aav vectors into the nucleus basalis of the basal forebrain led to clear and consistent elevation of the respective trophic factor as measured by enzyme-linked immunosorbent assay, with ngf vectors affecting the size and number of cholinergic neurons. |
2003-04-23 |
2023-08-12 |
Not clear |
| Aki Yuhara, Kyoko Ishii, Chika Nishio, Yasuhiro Abiru, Masashi Yamada, Hiroyuki Nawa, Hiroshi Hatanaka, Nobuyuki Take. PACAP and NGF cooperatively enhance choline acetyltransferase activity in postnatal basal forebrain neurons by complementary induction of its different mRNA species. Biochemical and biophysical research communications. vol 301. issue 2. 2003-04-15. PMID:12565866. |
both nerve growth factor (ngf) and pituitary adenylate cyclase activating polypeptide (pacap) have neurotrophic effects on basal forebrain cholinergic neurons. |
2003-04-15 |
2023-08-12 |
rat |
| Aki Yuhara, Kyoko Ishii, Chika Nishio, Yasuhiro Abiru, Masashi Yamada, Hiroyuki Nawa, Hiroshi Hatanaka, Nobuyuki Take. PACAP and NGF cooperatively enhance choline acetyltransferase activity in postnatal basal forebrain neurons by complementary induction of its different mRNA species. Biochemical and biophysical research communications. vol 301. issue 2. 2003-04-15. PMID:12565866. |
here we report on the cooperative effects of ngf and pacap on postnatal, but not embryonic, cholinergic neurons cultured from rat basal forebrain. |
2003-04-15 |
2023-08-12 |
rat |
| Aki Yuhara, Kyoko Ishii, Chika Nishio, Yasuhiro Abiru, Masashi Yamada, Hiroyuki Nawa, Hiroshi Hatanaka, Nobuyuki Take. PACAP and NGF cooperatively enhance choline acetyltransferase activity in postnatal basal forebrain neurons by complementary induction of its different mRNA species. Biochemical and biophysical research communications. vol 301. issue 2. 2003-04-15. PMID:12565866. |
these results explain the cooperative neurotrophic action of ngf and pacap on postnatal cholinergic neurons. |
2003-04-15 |
2023-08-12 |
rat |
| A I Brooks, D A Cory-Slechta, W J Bowers, S L Murg, H J Federof. Enhanced learning in mice parallels vector-mediated nerve growth factor expression in hippocampus. Human gene therapy. vol 11. issue 17. 2003-02-20. PMID:11096439. |
loss of a single ngf allele at the mouse ngf locus (heterozygous null, ngf(+/-)) reduces septohippocampal ngf levels and ngf-regulated cholinergic neurotransmitter enzymes and results in spatial learning deficits in adult animals. |
2003-02-20 |
2023-08-12 |
mouse |
| Takaki Miwa, Tetsuji Moriizumi, Isao Horikawa, Naoki Uramoto, Tadashi Ishimaru, Toshiro Nishimura, Mitsuru Furukaw. Role of nerve growth factor in the olfactory system. Microscopy research and technique. vol 58. issue 3. 2003-01-29. PMID:12203698. |
it has been shown that ngf in the olfactory bulb plays a role in the survival of cholinergic neurons in the horizontal limb of the diagonal band (hdb). |
2003-01-29 |
2023-08-12 |
mouse |