| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mengwen Shi, Jiaxin Tang, Chengmei Yang, Guanlong Guo, Huaxing Ou, Weihai Che. Pimavanserin, a 5-hydroxytryptamine 2A receptor inverse agonist, reverses prepulse inhibition deficits in the nucleus accumbens and ventral hippocampus. Neuropharmacology. vol 201. 2021-11-09. PMID:34666074. |
pimavanserin, a 5-hydroxytryptamine 2a receptor inverse agonist, reverses prepulse inhibition deficits in the nucleus accumbens and ventral hippocampus. |
2021-11-09 |
2023-08-13 |
Not clear |
| Francisco J Flores-Ramirez, Anapaula Themann, Jorge A Sierra-Fonseca, Israel Garcia-Carachure, Samuel A Castillo, Minerva Rodriguez, Omar Lira, Joshua Preciado-Piña, Brandon L Warren, Alfred J Robison, Sergio D Iñigue. Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:33833356. |
an additional goal was to assess the impact of adolescent flx pretreatment, and its re-exposure in adulthood, on serotonin transporters (5-htt) and brain-derived-neurotrophic-factor (bdnf)-related signaling markers (trkb-erk1/2-creb-probdnf-mbdnf) within the hippocampus and prefrontal cortex. |
2021-11-08 |
2023-08-13 |
mouse |
| Ke-Zhuo Chen, Shi Chen, Jie-Yi Ren, Shi Lin, Ming-Jun Xiao, Li Cheng, Xiao-Chuan Y. [Antidepressant effect of acidic polysaccharides from Poria and their regulation of neurotransmitters and NLRP3 pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 19. 2021-11-08. PMID:34738405. |
the results showed that compared with the model group, acidic polysaccharides from poria at the low-, medium-, and high-doses(0.1, 0.3 and 0.5 g·kg~(-1)·d~(-1)) all improved the depression-like behavior of rats, increased the number of neurons and the levels of bdnf, 5-ht, 5-hiaa, da, and ne in the hippocampus, and reduced glu and serum il-1β, il-18, and tnf-α levels. |
2021-11-08 |
2023-08-13 |
rat |
| Chen Li, Fantao Meng, Jacob C Garza, Jing Liu, Yun Lei, Sergei A Kirov, Ming Guo, Xin-Yun L. Modulation of depression-related behaviors by adiponectin AdipoR1 receptors in 5-HT neurons. Molecular psychiatry. vol 26. issue 8. 2021-11-02. PMID:31980728. |
the expression levels of tph2 were downregulated with a concurrent reduction of 5-ht-immunoreactivity in the drn and its two major projection regions, the hippocampus and medial prefrontal cortex (mpfc), in male but not female mice lacking adipor1 in 5-ht neurons. |
2021-11-02 |
2023-08-13 |
mouse |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
hippocampal neuroanatomy in first episode psychosis: a putative role for glutamate and serotonin receptors. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
disrupted serotonergic and glutamatergic signaling interact and contribute to the pathophysiology of schizophrenia, which is particularly relevant for the hippocampus where diverse expression of serotonin receptors is noted. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
we used gene expression data to correlate serotonin and glutamate receptor genes across the hippocampus. |
2021-11-01 |
2023-08-13 |
human |
| Min Tae M Park, Peter Jeon, Ali R Khan, Kara Dempster, M Mallar Chakravarty, Jason P Lerch, Michael MacKinley, Jean Théberge, Lena Palaniyappa. Hippocampal neuroanatomy in first episode psychosis: A putative role for glutamate and serotonin receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 110. 2021-11-01. PMID:33691200. |
we demonstrate a putative glutamate-driven hippocampal variability in fep through a serotonin receptor-density gated mechanism, thus outlining a mechanistic interplay between serotonin and glutamate in determining the hippocampal morphology in schizophrenia. |
2021-11-01 |
2023-08-13 |
human |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
after behavioral tests, various neurotransmitters including norepinephrine (ne), dopamine (da), serotonin (5-ht) and γ-aminobutyric acid (gaba) in mouse hippocampus were quantified using high performance liquid chromatography. |
2021-10-29 |
2023-08-13 |
mouse |
| Feng Tai, Che Wang, Xin Deng, Ruojin Li, Zimeng Guo, Haiying Quan, Song L. Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice. Brain research bulletin. vol 164. 2021-10-29. PMID:32877716. |
in addition, 2m-sd exposure increased ne and da, decreased 5-ht and gaba, and reduced igf-1 and bdnf levels in mouse hippocampus. |
2021-10-29 |
2023-08-13 |
mouse |
| Sepideh Saffarpour, Farinaz Nasirinezha. The CA1 hippocampal serotonin alterations involved in anxiety-like behavior induced by sciatic nerve injury in rats. Scandinavian journal of pain. vol 21. issue 1. 2021-10-28. PMID:32892185. |
the ca1 hippocampal serotonin alterations involved in anxiety-like behavior induced by sciatic nerve injury in rats. |
2021-10-28 |
2023-08-13 |
rat |
| Sepideh Saffarpour, Farinaz Nasirinezha. The CA1 hippocampal serotonin alterations involved in anxiety-like behavior induced by sciatic nerve injury in rats. Scandinavian journal of pain. vol 21. issue 1. 2021-10-28. PMID:32892185. |
the current study investigated the consequence of pain induced by peripheral neuropathy on the serotonin (5-ht) level of the ca1 region of the hippocampus, which is known as a potential reason, for anxiety associated with neuropathic pain. |
2021-10-28 |
2023-08-13 |
rat |
| Xiumin Liu, Wenhui Chen, Chenkang Wang, Weiwei Liu, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejim. Silibinin ameliorates depression/anxiety-like behaviors of Parkinson's disease mouse model and is associated with attenuated STING-IRF3-IFN-β pathway activation and neuroinflammation. Physiology & behavior. vol 241. 2021-10-27. PMID:34536434. |
silibinin significantly restored hippocampal levels of 5-hydroxyptramine (5-ht) and noradrenaline (na), two important neurotransmitters for regulating mood, which decreased in mptp-injected mice. |
2021-10-27 |
2023-08-13 |
mouse |
| Amar Sarkar, Siobhán Harty, Katerina V-A Johnson, Andrew H Moeller, Rachel N Carmody, Soili M Lehto, Susan E Erdman, Robin I M Dunbar, Philip W J Burne. The role of the microbiome in the neurobiology of social behaviour. Biological reviews of the Cambridge Philosophical Society. vol 95. issue 5. 2021-10-25. PMID:32383208. |
these include the structure and function of regions of the 'social' brain (the amygdala, the prefrontal cortex, and the hippocampus) and the regulation of 'social' signalling molecules (glucocorticoids including corticosterone and cortisol, sex hormones including testosterone, oestrogens, and progestogens, neuropeptide hormones such as oxytocin and arginine vasopressin, and monoamine neurotransmitters such as serotonin and dopamine). |
2021-10-25 |
2023-08-13 |
human |
| Bruno Carabelli, Ana Márcia Delattre, Ana Paula Farias Waltrick, Giulia Araújo, Deborah Suchecki, Ricardo Borges Machado, Luiz Eduardo Rizzo de Souza, Silvio M Zanata, Janaína Menezes Zanoveli, Anete Curte Ferra. Fish-oil supplementation decreases Indoleamine-2,3-Dioxygenase expression and increases hippocampal serotonin levels in the LPS depression model. Behavioural brain research. vol 390. 2021-10-25. PMID:32407816. |
fish-oil supplementation decreases indoleamine-2,3-dioxygenase expression and increases hippocampal serotonin levels in the lps depression model. |
2021-10-25 |
2023-08-13 |
Not clear |
| Wankupar Wankhar, Donkupar Syiem, Careen Liza Pakyntein, Daiahun Thabah, Shelareen Ediemi Sun. Effect of 5-HT Behavioural brain research. vol 393. 2021-10-25. PMID:32579979. |
using this animal model, we have attempted to understand the serotonergic system in the hippocampus and prefrontal cortex, while using the 5-ht |
2021-10-25 |
2023-08-13 |
Not clear |
| Fengmei Qiu, Xiaoming Zhong, Qingqiu Mao, Zhen Huan. The antidepressant-like effects of paeoniflorin in mouse models. Experimental and therapeutic medicine. vol 5. issue 4. 2021-10-25. PMID:23599734. |
paeoniflorin also significantly increased the levels of serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the hippocampus. |
2021-10-25 |
2023-08-12 |
mouse |
| Gali Umschweif, Lucian Medrihan, Kathryn A McCabe, Yotam Sagi, Paul Greengar. Activation of the p11/SMARCA3/Neurensin-2 pathway in parvalbumin interneurons mediates the response to chronic antidepressants. Molecular psychiatry. vol 26. issue 7. 2021-10-24. PMID:33723417. |
here we report that the p11/smarca3 complex represses neurensin-2 transcription in hippocampal parvalbumin-expressing interneurons after chronic treatment with selective serotonin reuptake inhibitors (ssri). |
2021-10-24 |
2023-08-13 |
Not clear |
| Cristiano Bombardi, Annamaria Grandis, Nela Pivac, Marina Sagud, Guillaume Lucas, Abdeslam Chagraoui, Valérie Lemaire-Mayo, Philippe De Deurwaerdère, Giuseppe Di Giovann. Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics. Progress in brain research. vol 261. 2021-10-22. PMID:33785139. |
serotonin modulation of hippocampal functions: from anatomy to neurotherapeutics. |
2021-10-22 |
2023-08-13 |
Not clear |
| Cristiano Bombardi, Annamaria Grandis, Nela Pivac, Marina Sagud, Guillaume Lucas, Abdeslam Chagraoui, Valérie Lemaire-Mayo, Philippe De Deurwaerdère, Giuseppe Di Giovann. Serotonin modulation of hippocampal functions: From anatomy to neurotherapeutics. Progress in brain research. vol 261. 2021-10-22. PMID:33785139. |
not surprisingly, several drugs acting via 5-ht mechanisms are efficacious to some extent in some diseases and the link between 5-ht and the hippocampus although clear remains difficult to untangle. |
2021-10-22 |
2023-08-13 |
Not clear |