| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Atsuhiko Sugiyama, Noriko Sato, Yukio Kimura, Tomoko Maekawa, Noritaka Wakasugi, Daichi Sone, Mikako Enokizono, Yuji Takahashi, Miho Murata, Hidehiro Mizusawa, Hiroshi Matsud. Thalamic involvement determined using VSRAD advance on MRI and easy Z-score analysis of Journal of the neurological sciences. vol 373. 2017-06-02. PMID:28131204. |
we present two cases of genetically proven gss102l, both of which present with atrophy and decreased blood flow of the thalamus as determined by voxel-based specific regional analysis system for alzheimer's disease (vsrad) advance software and easy z-score analysis for |
2017-06-02 |
2023-08-13 |
Not clear |
| Luca Passamonti, Patricia Vázquez Rodríguez, Young T Hong, Kieren S J Allinson, David Williamson, Robin J Borchert, Saber Sami, Thomas E Cope, W Richard Bevan-Jones, P Simon Jones, Robert Arnold, Ajenthan Surendranathan, Elijah Mak, Li Su, Tim D Fryer, Franklin I Aigbirhio, John T O'Brien, James B Row. 18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy. Brain : a journal of neurology. vol 140. issue 3. 2017-05-29. PMID:28122879. |
conversely, in patients with progressive supranuclear palsy, relative to patients with alzheimer's disease, 18f-av-1451 binding was elevated in the midbrain (t = 2.1, p < 0.04); while patients with progressive supranuclear palsy showed, relative to controls, increased 18f-av-1451 uptake in the putamen, pallidum, thalamus, midbrain, and in the dentate nucleus of the cerebellum (t's > 2.7, p's < 0.02). |
2017-05-29 |
2023-08-13 |
human |
| John P Aggleton, Agathe Pralus, Andrew J D Nelson, Michael Hornberge. Thalamic pathology and memory loss in early Alzheimer's disease: moving the focus from the medial temporal lobe to Papez circuit. Brain : a journal of neurology. vol 139. issue Pt 7. 2017-05-10. PMID:27190025. |
furthermore, this refocus on the limbic thalamus, as well as the rest of papez circuit, would have significant implications for the diagnostics, modelling, and experimental treatment of cognitive symptoms in alzheimer's disease. |
2017-05-10 |
2023-08-13 |
Not clear |
| John P Aggleton, Agathe Pralus, Andrew J D Nelson, Michael Hornberge. Thalamic pathology and memory loss in early Alzheimer's disease: moving the focus from the medial temporal lobe to Papez circuit. Brain : a journal of neurology. vol 139. issue Pt 7. 2017-05-10. PMID:27190025. |
the combined evidence indicates that the loss of episodic memory in early alzheimer's disease reflects much wider neurodegeneration in an extended mnemonic system (papez circuit), which critically involves the limbic thalamus. |
2017-05-10 |
2023-08-13 |
Not clear |
| Udo Rüb, Katharina Stratmann, Helmut Heinsen, Domenico Del Turco, Estifanos Ghebremedhin, Kay Seidel, Wilfred den Dunnen, Horst-Werner Kor. Hierarchical Distribution of the Tau Cytoskeletal Pathology in the Thalamus of Alzheimer's Disease Patients. Journal of Alzheimer's disease : JAD. vol 49. issue 4. 2016-10-28. PMID:26519431. |
in spite of considerable progress in neuropathological research on alzheimer's disease (ad), knowledge regarding the exact pathoanatomical distribution of the tau cytoskeletal pathology in the thalamus of ad patients in the advanced braak and braak ad stages v or vi of the cortical cytoskeletal pathology is still fragmentary. |
2016-10-28 |
2023-08-13 |
human |
| Xiaoying Tang, Dominic Holland, Anders M Dale, Laurent Younes, Michael I Mille. Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 2. 2015-09-21. PMID:25318546. |
this predictor is based on the shape diffeomorphometry patterns of subcortical and ventricular structures (left and right amygdala, hippocampus, thalamus, caudate, putamen, globus pallidus, and lateral ventricle) of 607 baseline scans from the alzheimer's disease neuroimaging initiative database, including a total of 210 healthy control subjects, 222 mci subjects, and 175 ad subjects. |
2015-09-21 |
2023-08-13 |
human |
| Shuai Qian, Lisi He, Marvin Mak, Yifan Han, Chun-Yu Ho, Zhong Zu. Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as acetylcholinesterase inhibitors. International journal of pharmaceutics. vol 477. issue 1-2. 2015-08-24. PMID:25445524. |
tacrine (tha), as the first approved acetylcholinesterase (ache) inhibitors for the treatment of alzheimer's disease (ad), has been extensively investigated in last seven decades. |
2015-08-24 |
2023-08-13 |
Not clear |
| Francesca Baglio, Ludovica Griffanti, Francesca Lea Saibene, Cristian Ricci, Margherita Alberoni, Raffaella Critelli, Fabiana Villanelli, Raffaella Fioravanti, Federica Mantovani, Alessandra D'amico, Monia Cabinio, Maria Giulia Preti, Raffaello Nemni, Elisabetta Farin. Multistimulation group therapy in Alzheimer's disease promotes changes in brain functioning. Neurorehabilitation and neural repair. vol 29. issue 1. 2015-08-19. PMID:24788581. |
the following significant intervention-related changes were observed: reduction in neuropsychiatric inventory scale score, improvement in language and memory subscales of alzheimer's disease assessment scale-cognitive subscale, and increased fmri activations in temporal brain areas, right insular cortex, and thalamus. |
2015-08-19 |
2023-08-13 |
Not clear |
| Chunpeng Gao, Yue Ding, Laifu Zhong, Liping Jiang, Chengyan Geng, Xiaofeng Yao, Jun Ca. Tacrine induces apoptosis through lysosome- and mitochondria-dependent pathway in HepG2 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 28. issue 4. 2015-06-29. PMID:24560791. |
administration of tha for the treatment of alzheimer's disease results in a reversible hepatotoxicity in 30-50% of patients, as indicated by elevated alanine aminotransferase levels. |
2015-06-29 |
2023-08-12 |
Not clear |
| Elizabeth G Kehoe, Dervla Farrell, Claudia Metzler-Baddeley, Brian A Lawlor, Rose Anne Kenny, Declan Lyons, Jonathan P McNulty, Paul G Mullins, Damien Coyle, Arun L Bokd. Fornix White Matter is Correlated with Resting-State Functional Connectivity of the Thalamus and Hippocampus in Healthy Aging but Not in Mild Cognitive Impairment - A Preliminary Study. Frontiers in aging neuroscience. vol 7. 2015-02-20. PMID:25698967. |
in this study, we wished to examine the relationship between the structural connectivity of the fornix, a white matter (wm) tract in the limbic system, which is affected in amnestic mild cognitive impairment (amci) and alzheimer's disease, and the resting-state functional connectivity (fc) of two key related subcortical structures, the thalamus, and hippocampus. |
2015-02-20 |
2023-08-13 |
Not clear |
| Hanna Cho, Jeong-Hun Kim, Changsoo Kim, Byoung Seok Ye, Hee Jin Kim, Cindy W Yoon, Young Noh, Geon Ha Kim, Yeo Jin Kim, Jung-Hyun Kim, Chang-Hun Kim, Sue J Kang, Juhee Chin, Sung Tae Kim, Kyung-Han Lee, Duk L Na, Joon-Kyung Seong, Sang Won Se. Shape changes of the basal ganglia and thalamus in Alzheimer's disease: a three-year longitudinal study. Journal of Alzheimer's disease : JAD. vol 40. issue 2. 2015-01-15. PMID:24413620. |
shape changes of the basal ganglia and thalamus in alzheimer's disease: a three-year longitudinal study. |
2015-01-15 |
2023-08-12 |
Not clear |
| Hanna Cho, Jeong-Hun Kim, Changsoo Kim, Byoung Seok Ye, Hee Jin Kim, Cindy W Yoon, Young Noh, Geon Ha Kim, Yeo Jin Kim, Jung-Hyun Kim, Chang-Hun Kim, Sue J Kang, Juhee Chin, Sung Tae Kim, Kyung-Han Lee, Duk L Na, Joon-Kyung Seong, Sang Won Se. Shape changes of the basal ganglia and thalamus in Alzheimer's disease: a three-year longitudinal study. Journal of Alzheimer's disease : JAD. vol 40. issue 2. 2015-01-15. PMID:24413620. |
a large number of alzheimer's disease (ad) studies have focused on medial temporal and cortical atrophy, while changes in the basal ganglia or thalamus have received less attention. |
2015-01-15 |
2023-08-12 |
Not clear |
| Irena Štěpán-Buksakowska, Nikoletta Szabó, Daniel Hořínek, Eszter Tóth, Jakub Hort, Joshua Warner, František Charvát, László Vécsei, Miloslav Roček, Zsigmond T Kincse. Cortical and subcortical atrophy in Alzheimer disease: parallel atrophy of thalamus and hippocampus. Alzheimer disease and associated disorders. vol 28. issue 1. 2014-10-01. PMID:23751371. |
cortical and subcortical atrophy in alzheimer disease: parallel atrophy of thalamus and hippocampus. |
2014-10-01 |
2023-08-12 |
Not clear |
| Bo Zhou, Yong Liu, Zengqiang Zhang, Ningyu An, Hongxiang Yao, Pan Wang, Luning Wang, Xi Zhang, Tianzi Jian. Impaired functional connectivity of the thalamus in Alzheimer's disease and mild cognitive impairment: a resting-state fMRI study. Current Alzheimer research. vol 10. issue 7. 2014-04-08. PMID:23905993. |
impaired functional connectivity of the thalamus in alzheimer's disease and mild cognitive impairment: a resting-state fmri study. |
2014-04-08 |
2023-08-12 |
Not clear |
| Yasuhisa Sakurai, Kenji Ishii, Masahiro Sonoo, Yuko Saito, Shigeo Murayama, Atsushi Iwata, Kensuke Hamada, Izumi Sugimoto, Shoji Tsuji, Toru Manne. Progressive apraxic agraphia with micrographia presenting as corticobasal syndrome showing extensive Pittsburgh compound B uptake. Journal of neurology. vol 260. issue 8. 2014-02-28. PMID:23589191. |
(18)f-fluoro-deoxy-glucose pet and single photon emission computed tomography with a (99m)tc-ethylcysteinate dimer (ecd-spect) also revealed predominantly right-sided hypometabolism and hypoperfusion in the primary sensorimotor cortex, posterior cingulate gyrus, temporoparietal cortices, frontal cortices, thalamus, and basal ganglia, a pattern characteristic of both corticobasal degeneration and alzheimer's disease. |
2014-02-28 |
2023-08-12 |
Not clear |
| Venugopalan Y Vishn. Implications of presymptomatic change in thalamus and caudate in Alzheimer's disease. Brain : a journal of neurology. vol 136. issue Pt 11. 2013-12-31. PMID:23824489. |
implications of presymptomatic change in thalamus and caudate in alzheimer's disease. |
2013-12-31 |
2023-08-12 |
Not clear |
| Natalie S Ryan, Nick C Fo. Reply: Implications of presymptomatic change in thalamus and caudate in Alzheimer's disease. Brain : a journal of neurology. vol 136. issue Pt 11. 2013-12-31. PMID:23824491. |
reply: implications of presymptomatic change in thalamus and caudate in alzheimer's disease. |
2013-12-31 |
2023-08-12 |
Not clear |
| Chunpeng Gao, Laifu Zhong, Liping Jiang, Chengyan Geng, Xiaofeng Yao, Jun Ca. Phellinus linteus mushroom protects against tacrine-induced mitochondrial impairment and oxidative stress in HepG2 cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 20. issue 8-9. 2013-12-24. PMID:23523257. |
tacrine (tha) was the first drug licensed for the treatment of alzheimer's disease. |
2013-12-24 |
2023-08-12 |
Not clear |
| Tatiane Pedro, Marina Weiler, Clarissa L Yasuda, Anelyssa D'Abreu, Benito P Damasceno, Fernando Cendes, Marcio L F Balthaza. Volumetric brain changes in thalamus, corpus callosum and medial temporal structures: mild Alzheimer's disease compared with amnestic mild cognitive impairment. Dementia and geriatric cognitive disorders. vol 34. issue 3-4. 2013-07-02. PMID:22986782. |
volumetric brain changes in thalamus, corpus callosum and medial temporal structures: mild alzheimer's disease compared with amnestic mild cognitive impairment. |
2013-07-02 |
2023-08-12 |
Not clear |
| Natalie S Ryan, Shiva Keihaninejad, Timothy J Shakespeare, Manja Lehmann, Sebastian J Crutch, Ian B Malone, John S Thornton, Laura Mancini, Harpreet Hyare, Tarek Yousry, Gerard R Ridgway, Hui Zhang, Marc Modat, Daniel C Alexander, Martin N Rossor, Sebastien Ourselin, Nick C Fo. Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease. Brain : a journal of neurology. vol 136. issue Pt 5. 2013-06-24. PMID:23539189. |
magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial alzheimer's disease. |
2013-06-24 |
2023-08-12 |
human |