| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yehezkel Ben-Ar. Is birth a critical period in the pathogenesis of autism spectrum disorders? Nature reviews. Neuroscience. vol 16. issue 8. 2015-10-06. PMID:26152864. |
in this opinion article, i discuss the links between birth-related stressful mechanisms, persistent excitatory gaba actions, perturbed network oscillations and autism. |
2015-10-06 |
2023-08-13 |
Not clear |
| Hongjie Yuan, Chian-Ming Low, Olivia A Moody, Andrew Jenkins, Stephen F Trayneli. Ionotropic GABA and Glutamate Receptor Mutations and Human Neurologic Diseases. Molecular pharmacology. vol 88. issue 1. 2015-08-11. PMID:25904555. |
in addition, a substantial number of variants and mutations have been found in gaba receptor genes in patients with autism, schizophrenia, and addiction, suggesting potential links between the gaba receptors and these conditions. |
2015-08-11 |
2023-08-13 |
human |
| Maiken K Brix, Lars Ersland, Kenneth Hugdahl, Renate Grüner, Maj-Britt Posserud, Åsa Hammar, Alexander R Craven, Ralph Noeske, C John Evans, Hanne B Walker, Tore Midtvedt, Mona K Beye. "Brain MR spectroscopy in autism spectrum disorder-the GABA excitatory/inhibitory imbalance theory revisited". Frontiers in human neuroscience. vol 9. 2015-07-09. PMID:26157380. |
our main aims were to compare the concentration of γ-aminobutyric acid (gaba) between the two groups, and to investigate the relationship between brain metabolites and autism symptom severity in the asd group. |
2015-07-09 |
2023-08-13 |
Not clear |
| L L Jantzie, P M Getsy, D J Firl, C G Wilson, R H Miller, S Robinso. Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury. Molecular and cellular neurosciences. vol 61. 2015-04-15. PMID:24983520. |
therapeutic agents that restore the inhibitory actions of γ-amino butyric acid (gaba) by modulating intracellular chloride concentrations will provide novel avenues to treat stroke, chronic pain, epilepsy, autism, and neurodegenerative and cognitive disorders. |
2015-04-15 |
2023-08-13 |
human |
| Maria Dorota Majewska, Martin Hill, Ewa Urbanowicz, Paulina Rok-Bujko, Przemysław Bieńkowski, Irena Namysłowska, Paweł Mierzejewsk. Marked elevation of adrenal steroids, especially androgens, in saliva of prepubertal autistic children. European child & adolescent psychiatry. vol 23. issue 6. 2014-11-14. PMID:24043498. |
some steroids, whose levels are raised in autism (allopregnanolone, androsterone, pregnenolone, dehydroepiandrosterone and their sulfate conjugates) are neuroactive and modulate gaba, glutamate, and opioid neurotransmission, affecting brain development and functioning. |
2014-11-14 |
2023-08-12 |
Not clear |
| Tatsuya Hayama, Haruo Kasa. [A new role of GABA on synapses]. Brain and nerve = Shinkei kenkyu no shinpo. vol 66. issue 8. 2014-11-13. PMID:25082320. |
the selection of synapses is key to the reorganization of the central nervous system during development and in adulthood, and gaba plays key roles in various mental disorders, such as autism and schizophrenia. |
2014-11-13 |
2023-08-13 |
Not clear |
| Victorio Bambini-Junior, Gustavo Della Flora Nunes, Tomasz Schneider, Carmem Gottfrie. Comment on "Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring". Science (New York, N.Y.). vol 346. issue 6206. 2014-11-03. PMID:25301610. |
comment on "oxytocin-mediated gaba inhibition during delivery attenuates autism pathogenesis in rodent offspring". |
2014-11-03 |
2023-08-13 |
Not clear |
| Victorio Bambini-Junior, Gustavo Della Flora Nunes, Tomasz Schneider, Carmem Gottfrie. Comment on "Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring". Science (New York, N.Y.). vol 346. issue 6206. 2014-11-03. PMID:25301610. |
(reports, 7 february 2014, p. 675) reported that bumetanide restored the impaired oxytocin-mediated γ-aminobutyric acid (gaba) excitatory-inhibitory shift during delivery in animal models of autism, ameliorating some autistic-like characteristics in the offspring. |
2014-11-03 |
2023-08-13 |
Not clear |
| Sanaz Eftekhari, Amene Shahrokhi, Vera Tsintsadze, Romain Nardou, Corinne Brouchoud, Magali Conesa, Nail Burnashev, Diana C Ferrari, Yehezkel Ben-Ar. Response to Comment on "Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring". Science (New York, N.Y.). vol 346. issue 6206. 2014-11-03. PMID:25301611. |
response to comment on "oxytocin-mediated gaba inhibition during delivery attenuates autism pathogenesis in rodent offspring". |
2014-11-03 |
2023-08-13 |
Not clear |
| Carla V Sesarini, Lucas Costa, Muriel Naymark, Nora Grañana, Andrea R Cajal, Miguel García Coto, Roberto C Pallia, Pablo F Argiba. Evidence for interaction between markers in GABA(A) receptor subunit genes in an Argentinean autism spectrum disorder population. Autism research : official journal of the International Society for Autism Research. vol 7. issue 1. 2014-10-28. PMID:24249596. |
evidence for interaction between markers in gaba(a) receptor subunit genes in an argentinean autism spectrum disorder population. |
2014-10-28 |
2023-08-12 |
Not clear |
| S Hossein Fatemi, Teri J Reutiman, Timothy D Folsom, Oyvind G Rustan, Robert J Rooney, Paul D Thura. Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism. Journal of autism and developmental disorders. vol 44. issue 8. 2014-10-20. PMID:24668190. |
we measured protein and mrna levels for nine gamma-aminobutyric acid a (gabaa) receptor subunits in three brain regions (cerebellum, superior frontal cortex, and parietal cortex) in subjects with autism versus matched controls. |
2014-10-20 |
2023-08-12 |
human |
| Donald C Rojas, Debra Singel, Sarah Steinmetz, Susan Hepburn, Mark S Brow. Decreased left perisylvian GABA concentration in children with autism and unaffected siblings. NeuroImage. vol 86. 2014-09-03. PMID:23370056. |
decreased left perisylvian gaba concentration in children with autism and unaffected siblings. |
2014-09-03 |
2023-08-12 |
human |
| Donald C Rojas, Debra Singel, Sarah Steinmetz, Susan Hepburn, Mark S Brow. Decreased left perisylvian GABA concentration in children with autism and unaffected siblings. NeuroImage. vol 86. 2014-09-03. PMID:23370056. |
although proton magnetic resonance spectroscopy ((1)h-mrs) studies have been published on various metabolite levels in autism, including glutamate, the major excitatory neurotransmitter, few (1)h-mrs studies have yet been conducted the major inhibitory neurotransmitter gaba. |
2014-09-03 |
2023-08-12 |
human |
| Donald C Rojas, Debra Singel, Sarah Steinmetz, Susan Hepburn, Mark S Brow. Decreased left perisylvian GABA concentration in children with autism and unaffected siblings. NeuroImage. vol 86. 2014-09-03. PMID:23370056. |
reduced auditory gaba concentration in asd is consistent with one previous mrs study of gaba concentration in the frontal lobe in autism, suggesting that multiple neocortical areas may be involved. |
2014-09-03 |
2023-08-12 |
human |
| Gabriele Deidda, Ignacio F Bozarth, Laura Cancedd. Modulation of GABAergic transmission in development and neurodevelopmental disorders: investigating physiology and pathology to gain therapeutic perspectives. Frontiers in cellular neuroscience. vol 8. 2014-06-24. PMID:24904277. |
according to its functional importance during development, gaba is implicated in a number of neurodevelopmental disorders such as autism, fragile x, rett syndrome, down syndrome, schizophrenia, tourette's syndrome and neurofibromatosis. |
2014-06-24 |
2023-08-13 |
Not clear |
| Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal, Eric Lemonnier, Natalia Lozovaya, Nail Burnashev, Yehezkel Ben-Ar. Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. Science (New York, N.Y.). vol 343. issue 6171. 2014-02-25. PMID:24503856. |
oxytocin-mediated gaba inhibition during delivery attenuates autism pathogenesis in rodent offspring. |
2014-02-25 |
2023-08-12 |
Not clear |
| Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal, Eric Lemonnier, Natalia Lozovaya, Nail Burnashev, Yehezkel Ben-Ar. Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring. Science (New York, N.Y.). vol 343. issue 6171. 2014-02-25. PMID:24503856. |
we report that the oxytocin-mediated neuroprotective γ-aminobutyric acid (gaba) excitatory-inhibitory shift during delivery is abolished in the valproate and fragile x rodent models of autism. |
2014-02-25 |
2023-08-12 |
Not clear |
| Varun Warrier, Simon Baron-Cohen, Bhismadev Chakrabart. Genetic variation in GABRB3 is associated with Asperger syndrome and multiple endophenotypes relevant to autism. Molecular autism. vol 4. issue 1. 2014-01-28. PMID:24321478. |
the gamma-aminobutyric acid (gaba)-ergic system has been associated consistently with atypicalities in autism, in both genetic association and expression studies. |
2014-01-28 |
2023-08-12 |
Not clear |
| Anthony J Russ. Correlation Between Hepatocyte Growth Factor (HGF) and Gamma-Aminobutyric Acid (GABA) Plasma Levels in Autistic Children. Biomarker insights. vol 8. 2013-07-05. PMID:23825437. |
there is much support for the role of gamma-aminobutyric acid (gaba) in the etiology of autism. |
2013-07-05 |
2023-08-12 |
Not clear |
| Jing-Qiong Kang, Gregory Barne. A common susceptibility factor of both autism and epilepsy: functional deficiency of GABA A receptors. Journal of autism and developmental disorders. vol 43. issue 1. 2013-06-28. PMID:22555366. |
a common susceptibility factor of both autism and epilepsy: functional deficiency of gaba a receptors. |
2013-06-28 |
2023-08-12 |
Not clear |