All Relations between Alzheimer Disease and microtubule-associated protein tau

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Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf, Céline Bellenguez, Aura Frizatti, Vincent Chouraki, Eden R Martin, Kristel Sleegers, Nandini Badarinarayan, Johanna Jakobsdottir, Kara L Hamilton-Nelson, Sonia Moreno-Grau, Robert Olaso, Rachel Raybould, Yuning Chen, Amanda B Kuzma, Mikko Hiltunen, Taniesha Morgan, Shahzad Ahmad, Badri N Vardarajan, Jacques Epelbaum, Per Hoffmann, Merce Boada, Gary W Beecham, Jean-Guillaume Garnier, Denise Harold, Annette L Fitzpatrick, Otto Valladares, Marie-Laure Moutet, Amy Gerrish, Albert V Smith, Liming Qu, Delphine Bacq, Nicola Denning, Xueqiu Jian, Yi Zhao, Maria Del Zompo, Nick C Fox, Seung-Hoan Choi, Ignacio Mateo, Joseph T Hughes, Hieab H Adams, John Malamon, Florentino Sanchez-Garcia, Yogen Patel, Jennifer A Brody, Beth A Dombroski, Maria Candida Deniz Naranjo, Makrina Daniilidou, Gudny Eiriksdottir, Shubhabrata Mukherjee, David Wallon, James Uphill, Thor Aspelund, Laura B Cantwell, Fabienne Garzia, Daniela Galimberti, Edith Hofer, Mariusz Butkiewicz, Bertrand Fin, Elio Scarpini, Chloe Sarnowski, Will S Bush, Stéphane Meslage, Johannes Kornhuber, Charles C White, Yuenjoo Song, Robert C Barber, Sebastiaan Engelborghs, Sabrina Sordon, Dina Voijnovic, Perrie M Adams, Rik Vandenberghe, Manuel Mayhaus, L Adrienne Cupples, Marilyn S Albert, Peter P De Deyn, Wei Gu, Jayanadra J Himali, Duane Beekly, Alessio Squassina, Annette M Hartmann, Adelina Orellana, Deborah Blacker, Eloy Rodriguez-Rodriguez, Simon Lovestone, Melissa E Garcia, Rachelle S Doody, Carmen Munoz-Fernadez, Rebecca Sussams, Honghuang Lin, Thomas J Fairchild, Yolanda A Benito, Clive Holmes, Hata Karamujić-Čomić, Matthew P Frosch, Hakan Thonberg, Wolfgang Maier, Gennady Roshchupkin, Bernardino Ghetti, Vilmantas Giedraitis, Amit Kawalia, Shuo Li, Ryan M Huebinger, Lena Kilander, Susanne Moebus, Isabel Hernández, M Ilyas Kamboh, RoseMarie Brundin, James Turton, Qiong Yang, Mindy J Katz, Letizia Concari, Jenny Lord, Alexa S Beiser, C Dirk Keene, Seppo Helisalmi, Iwona Kloszewska, Walter A Kukull, Anne Maria Koivisto, Aoibhinn Lynch, Lluís Tarraga, Eric B Larson, Annakaisa Haapasalo, Brian Lawlor, Thomas H Mosley, Richard B Lipton, Vincenzo Solfrizzi, Michael Gill, W T Longstreth, Thomas J Montine, Vincenza Frisardi, Monica Diez-Fairen, Fernando Rivadeneira, Ronald C Petersen, Vincent Deramecourt, Ignacio Alvarez, Francesca Salani, Antonio Ciaramella, Eric Boerwinkle, Eric M Reiman, Nathalie Fievet, Jerome I Rotter, Joan S Reisch, Olivier Hanon, Chiara Cupidi, A G Andre Uitterlinden, Donald R Royall, Carole Dufouil, Raffaele Giovanni Maletta, Itziar de Rojas, Mary Sano, Alexis Brice, Roberta Cecchetti, Peter St George-Hyslop, Karen Ritchie, Magda Tsolaki, Debby W Tsuang, Bruno Dubois, David Craig, Chuang-Kuo Wu, Hilkka Soininen, Despoina Avramidou, Roger L Albin, Laura Fratiglioni, Antonia Germanou, Liana G Apostolova, Lina Keller, Maria Koutroumani, Steven E Arnold, Francesco Panza, Olymbia Gkatzima, Sanjay Asthana, Didier Hannequin, Patrice Whitehead, Craig S Atwood, Paolo Caffarra, Harald Hampel, Inés Quintela, Ángel Carracedo, Lars Lannfelt, David C Rubinsztein, Lisa L Barnes, Florence Pasquier, Lutz Frölich, Sandra Barral, Bernadette McGuinness, Thomas G Beach, Janet A Johnston, James T Becker, Peter Passmore, Eileen H Bigio, Jonathan M Schott, Thomas D Bird, Jason D Warren, Bradley F Boeve, Michelle K Lupton, James D Bowen, Petra Proitsi, Adam Boxer, John F Powell, James R Burke, John S K Kauwe, Jeffrey M Burns, Michelangelo Mancuso, Joseph D Buxbaum, Ubaldo Bonuccelli, Nigel J Cairns, Andrew McQuillin, Chuanhai Cao, Gill Livingston, Chris S Carlson, Nicholas J Bass, Cynthia M Carlsson, John Hardy, Regina M Carney, Jose Bras, Minerva M Carrasquillo, Rita Guerreiro, Mariet Allen, Helena C Chui, Elizabeth Fisher, Carlo Masullo, Elizabeth A Crocco, Charles DeCarli, Gina Bisceglio, Malcolm Dick, Li Ma, Ranjan Duara, Neill R Graff-Radford, Denis A Evans, Angela Hodges, Kelley M Faber, Martin Scherer, Kenneth B Fallon, Matthias Riemenschneider, David W Fardo, Reinhard Heun, Martin R Farlow, Heike Kölsch, Steven Ferris, Markus Leber, Tatiana M Foroud, Isabella Heuser, Douglas R Galasko, Ina Giegling, Marla Gearing, Michael Hüll, Daniel H Geschwind, John R Gilbert, John Morris, Robert C Green, Kevin Mayo, John H Growdon, Thomas Feulner, Ronald L Hamilton, Lindy E Harrell, Dmitriy Drichel, Lawrence S Honig, Thomas D Cushion, Matthew J Huentelman, Paul Hollingworth, Christine M Hulette, Bradley T Hyman, Rachel Marshall, Gail P Jarvik, Alun Meggy, Erin Abner, Georgina E Menzies, Lee-Way Jin, Ganna Leonenko, Luis M Real, Gyungah R Jun, Clinton T Baldwin, Detelina Grozeva, Anna Karydas, Giancarlo Russo, Jeffrey A Kaye, Ronald Kim, Frank Jessen, Neil W Kowall, Bruno Vellas, Joel H Kramer, Emma Vardy, Frank M LaFerla, Karl-Heinz Jöckel, James J Lah, Martin Dichgans, James B Leverenz, David Mann, Allan I Levey, Stuart Pickering-Brown, Andrew P Lieberman, Norman Klopp, Kathryn L Lunetta, H-Erich Wichmann, Constantine G Lyketsos, Kevin Morgan, Daniel C Marson, Kristelle Brown, Frank Martiniuk, Christopher Medway, Deborah C Mash, Markus M Nöthen, Eliezer Masliah, Nigel M Hooper, Wayne C McCormick, Antonio Daniele, Susan M McCurry, Anthony Bayer, Andrew N McDavid, John Gallacher, Ann C McKee, Hendrik van den Bussche, Marsel Mesulam, Carol Brayne, Bruce L Miller, Steffi Riedel-Heller, Carol A Miller, Joshua W Miller, Ammar Al-Chalabi, John C Morris, Christopher E Shaw, Amanda J Myers, Jens Wiltfang, Sid O'Bryant, John M Olichney, Victoria Alvarez, Joseph E Parisi, Andrew B Singleton, Henry L Paulson, John Collinge, William R Perry, Simon Mead, Elaine Peskind, David H Cribbs, Martin Rossor, Aimee Pierce, Natalie S Ryan, Wayne W Poon, Benedetta Nacmias, Huntington Potter, Sandro Sorbi, Joseph F Quinn, Eleonora Sacchinelli, Ashok Raj, Gianfranco Spalletta, Murray Raskind, Carlo Caltagirone, Paola Bossù, Maria Donata Orfei, Barry Reisberg, Robert Clarke, Christiane Reitz, A David Smith, John M Ringman, Donald Warden, Erik D Roberson, Gordon Wilcock, Ekaterina Rogaeva, Amalia Cecilia Bruni, Howard J Rosen, Maura Gallo, Roger N Rosenberg, Yoav Ben-Shlomo, Mark A Sager, Patrizia Mecocci, Andrew J Saykin, Pau Pastor, Michael L Cuccaro, Jeffery M Vance, Julie A Schneider, Lori S Schneider, Susan Slifer, William W Seeley, Amanda G Smith, Joshua A Sonnen, Salvatore Spina, Robert A Stern, Russell H Swerdlow, Mitchell Tang, Rudolph E Tanzi, John Q Trojanowski, Juan C Troncoso, Vivianna M Van Deerlin, Linda J Van Eldik, Harry V Vinters, Jean Paul Vonsattel, Sandra Weintraub, Kathleen A Welsh-Bohmer, Kirk C Wilhelmsen, Jennifer Williamson, Thomas S Wingo, Randall L Woltjer, Clinton B Wright, Chang-En Yu, Lei Yu, Yasaman Saba, Alberto Pilotto, Maria J Bullido, Oliver Peters, Paul K Crane, David Bennett, Paola Bosco, Eliecer Coto, Virginia Boccardi, Phil L De Jager, Alberto Lleo, Nick Warner, Oscar L Lopez, Martin Ingelsson, Panagiotis Deloukas, Carlos Cruchaga, Caroline Graff, Rhian Gwilliam, Myriam Fornage, Alison M Goate, Pascual Sanchez-Juan, Patrick G Kehoe, Najaf Amin, Nilifur Ertekin-Taner, Claudine Berr, Stéphanie Debette, Seth Love, Lenore J Launer, Steven G Younkin, Jean-Francois Dartigues, Chris Corcoran, M Arfan Ikram, Dennis W Dickson, Gael Nicolas, Dominique Campion, JoAnn Tschanz, Helena Schmidt, Hakon Hakonarson, Jordi Clarimon, Ron Munger, Reinhold Schmidt, Lindsay A Farrer, Christine Van Broeckhoven, Michael C O'Donovan, Anita L DeStefano, Lesley Jones, Jonathan L Haines, Jean-Francois Deleuze, Michael J Owen, Vilmundur Gudnason, Richard Mayeux, Valentina Escott-Price, Bruce M Psaty, Alfredo Ramirez, Li-San Wang, Agustin Ruiz, Cornelia M van Duijn, Peter A Holmans, Sudha Seshadri, Julie Williams, Phillippe Amouyel, Gerard D Schellenberg, Jean-Charles Lambert, Margaret A Pericak-Vanc. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature genetics. vol 51. issue 9. 2021-07-03. PMID:31417202. author correction: genetic meta-analysis of diagnosed alzheimer's disease identifies new risk loci and implicates aβ, tau, immunity and lipid processing. 2021-07-03 2023-08-13 Not clear
Konstantinos Chiotis, Irina Savitcheva, Konstantinos Poulakis, Laure Saint-Aubert, Anders Wall, Gunnar Antoni, Agneta Nordber. [ Molecular psychiatry. 2021-07-03. PMID:32616831. [ cross-sectional studies have indicated potential for positron emission tomography (pet) in imaging tau pathology in alzheimer's disease (ad); however, its prognostic utility remains unproven. 2021-07-03 2023-08-13 human
Syed Faraz Kazim, Joon Ho Seo, Riccardo Bianchi, Chloe S Larson, Abhijeet Sharma, Robert K S Wong, Kirill Y Gorbachev, Ana C Pereir. Neuronal Network Excitability in Alzheimer's Disease: The Puzzle of Similar versus Divergent Roles of Amyloid β and Tau. eNeuro. vol 8. issue 2. 2021-07-02. PMID:33741601. neuronal network excitability in alzheimer's disease: the puzzle of similar versus divergent roles of amyloid β and tau. 2021-07-02 2023-08-13 Not clear
Lindsay E Stoyka, Casey L Mahoney, Drake R Thrasher, Drèson L Russell, Anna K Cook, Anner T Harris, Ashwin Narayanan, Tiara P Janado, David G Standaert, Erik D Roberson, Laura A Volpicelli-Dale. Templated α-Synuclein Inclusion Formation Is Independent of Endogenous Tau. eNeuro. vol 8. issue 3. 2021-07-02. PMID:33972291. reducing endogenous tau levels is protective in multiple models of alzheimer's disease (ad), tauopathies, and in some transgenic synucleinopathy mouse models. 2021-07-02 2023-08-13 mouse
Yao Sun, Yongqing Guo, Xuejian Feng, Lu Fu, Yayuan Zheng, Yue Dong, Yong Zhang, Xianghui Yu, Wei Kong, Hui W. Correction to: Norovirus P particle-based tau vaccine-generated phosphorylated tau antibodies markedly ameliorate tau pathology and improve behavioral deficits in mouse model of Alzheimer's disease. Signal transduction and targeted therapy. vol 6. issue 1. 2021-07-02. PMID:34127646. correction to: norovirus p particle-based tau vaccine-generated phosphorylated tau antibodies markedly ameliorate tau pathology and improve behavioral deficits in mouse model of alzheimer's disease. 2021-07-02 2023-08-13 mouse
Kimberly L Fiock, Jodi D Smith, John F Crary, Marco M Heft. β-amyloid and tau pathology in the aging feline brain. The Journal of comparative neurology. vol 528. issue 1. 2021-07-01. PMID:31273784. domestic cats (felis catus) are known to develop cognitive impairment, and several small series have demonstrated both β-amyloid and tau aggregation, including neurofibrillary tangles, with age, making them a promising physiologic model of alzheimer disease (ad). 2021-07-01 2023-08-13 human
Basim A S Messiha, Mohammed R A Ali, Mahmoud M Khattab, Amira M Abo-Yousse. Perindopril ameliorates experimental Alzheimer's disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signaling. Inflammopharmacology. vol 28. issue 5. 2021-07-01. PMID:32488543. accumulating evidence indicates that over-stimulation of angiotensin-converting enzyme 1 (ace1) activity is associated with β-amyloid (aβ) and phosphorylated tau (p-tau)-induced apoptosis, oxido-nitrosative neuroinflammatory stress and neurodegeneration in alzheimer's disease (ad). 2021-07-01 2023-08-13 rat
Senthilvelrajan Kaniyappan, Katharina Tepper, Jacek Biernat, Ram Reddy Chandupatla, Sabrina Hübschmann, Stephan Irsen, Sandra Bicher, Christoph Klatt, Eva-Maria Mandelkow, Eckhard Mandelko. FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments. Molecular neurodegeneration. vol 15. issue 1. 2021-07-01. PMID:32677995. tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several tauopathies, including alzheimer disease (ad). 2021-07-01 2023-08-13 Not clear
Shinichiro Ochi, Jun-Ichi Iga, Yu Funahashi, Yuta Yoshino, Kiyohiro Yamazaki, Hiroshi Kumon, Hiroaki Mori, Yuki Ozaki, Takaaki Mori, Shu-Ichi Uen. Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice. Molecular neurobiology. vol 57. issue 12. 2021-07-01. PMID:32816243. the testing of pathological biomarkers of alzheimer's disease (ad), such as amyloid beta and tau, is time-consuming, expensive, and invasive. 2021-07-01 2023-08-13 mouse
Sanjib Guha, Gail V W Johnson, Keith Nehrk. The Crosstalk Between Pathological Tau Phosphorylation and Mitochondrial Dysfunction as a Key to Understanding and Treating Alzheimer's Disease. Molecular neurobiology. vol 57. issue 12. 2021-07-01. PMID:32851560. the crosstalk between pathological tau phosphorylation and mitochondrial dysfunction as a key to understanding and treating alzheimer's disease. 2021-07-01 2023-08-13 Not clear
Chanisa Chotipanich, Monchaya Nivorn, Anchisa Kunawudhi, Chetsadaporn Promteangtrong, Natphimol Boonkawin, Attapon Jantarat. Evaluation of Imaging Windows for Tau PET Imaging Using Molecular imaging. vol 19. 2021-07-01. PMID:32862780. evaluation of imaging windows for tau pet imaging using the study aimed to evaluate the appropriate uptake-timing in cognitively normal individuals, mild cognitive impairment (mci), and alzheimer's disease (ad) patients, using 2021-07-01 2023-08-13 Not clear
Khadgawat Priya, J M Siddesha, Shashank Dharini, K Prasad Shashank. Interacting Models of Amyloid-β and Tau Proteins: An Approach to Identify Drug Targets in Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 5. issue 1. 2021-07-01. PMID:34189412. interacting models of amyloid-β and tau proteins: an approach to identify drug targets in alzheimer's disease. 2021-07-01 2023-08-13 Not clear
Mikael Marttinen, Catarina B Ferreira, Kaisa M A Paldanius, Mari Takalo, Teemu Natunen, Petra Mäkinen, Luukas Leppänen, Ville Leinonen, Kenji Tanigaki, Gina Kang, Noboru Hiroi, Hilkka Soininen, Kirsi Rilla, Annakaisa Haapasalo, Mikko Hiltune. Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ. Cells. vol 9. issue 11. 2021-06-30. PMID:33203136. alzheimer's disease (ad) is a neurodegenerative disease characterized by aberrant amyloid-β (aβ) and hyperphosphorylated tau aggregation. 2021-06-30 2023-08-13 mouse
Lalitha Venkataraman, Ping He, Philip Schulz, Michael R Sierk. Isolation and characterization of antibody fragment selective for human Alzheimer's disease brain-derived tau variants. Neurobiology of aging. vol 94. 2021-06-29. PMID:32497877. isolation and characterization of antibody fragment selective for human alzheimer's disease brain-derived tau variants. 2021-06-29 2023-08-13 human
Lalitha Venkataraman, Ping He, Philip Schulz, Michael R Sierk. Isolation and characterization of antibody fragment selective for human Alzheimer's disease brain-derived tau variants. Neurobiology of aging. vol 94. 2021-06-29. PMID:32497877. reagents that can selectively recognize specific toxic tau variants associated with onset and progression of alzheimer's disease (ad) and other tauopathies can be effective diagnostic and therapeutic tools. 2021-06-29 2023-08-13 human
Lalitha Venkataraman, Ping He, Philip Schulz, Michael R Sierk. Isolation and characterization of antibody fragment selective for human Alzheimer's disease brain-derived tau variants. Neurobiology of aging. vol 94. 2021-06-29. PMID:32497877. we identified 6 scfvs [alzheimer's disease tau (adt)-1 through 6] that readily distinguished between ad and control tissue and sera samples. 2021-06-29 2023-08-13 human
Michael A Sugarman, Henrik Zetterberg, Kaj Blennow, Yorghos Tripodis, Ann C McKee, Thor D Stein, Brett Martin, Joseph N Palmisano, Eric G Steinberg, Irene Simkin, Andrew E Budson, Ronald Killiany, Maureen K O'Connor, Rhoda Au, Wendy Wei Qiao Qiu, Lee E Goldstein, Neil W Kowall, Jesse Mez, Robert A Stern, Michael L Alosc. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiology of aging. vol 94. 2021-06-29. PMID:32585491. a longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of alzheimer's disease. 2021-06-29 2023-08-13 human
Michael A Sugarman, Henrik Zetterberg, Kaj Blennow, Yorghos Tripodis, Ann C McKee, Thor D Stein, Brett Martin, Joseph N Palmisano, Eric G Steinberg, Irene Simkin, Andrew E Budson, Ronald Killiany, Maureen K O'Connor, Rhoda Au, Wendy Wei Qiao Qiu, Lee E Goldstein, Neil W Kowall, Jesse Mez, Robert A Stern, Michael L Alosc. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiology of aging. vol 94. 2021-06-29. PMID:32585491. we examined baseline and longitudinal associations between plasma neurofilament light (nfl) and total tau (t-tau), and the clinical presentation of alzheimer's disease (ad). 2021-06-29 2023-08-13 human
Frank S Fa. Assessing the Possible Influence of Residues of Ractopamine, a Livestock Feed Additive, in Meat on Alzheimer Disease. Dementia and geriatric cognitive disorders extra. vol 11. issue 2. 2021-06-29. PMID:34178014. finally, it has been demonstrated that the β-adrenergic agonist salbutamol could bind directly to tau protein and interfere with the tau filament formation seen in the prodromal phase of alzheimer disease. 2021-06-29 2023-08-13 mouse
Jane Tulloch, Olga Netsyk, Eleanor K Pickett, Abigail G Herrmann, Pooja Jain, Anna J Stevenson, Iris Oren, Oliver Hardt, Tara L Spires-Jone. Maintained memory and long-term potentiation in a mouse model of Alzheimer's disease with both amyloid pathology and human tau. The European journal of neuroscience. vol 53. issue 2. 2021-06-28. PMID:33169893. maintained memory and long-term potentiation in a mouse model of alzheimer's disease with both amyloid pathology and human tau. 2021-06-28 2023-08-13 mouse