| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anne B Kim, Zoe Arvanitaki. Insulin resistance, cognition, and Alzheimer disease. Obesity (Silver Spring, Md.). vol 31. issue 6. 2023-05-19. PMID:37203336. |
insulin resistance, cognition, and alzheimer disease. |
2023-05-19 |
2023-08-14 |
Not clear |
| Wenqiang Chen, Qian Huang, Ekaterina Katie Lazdon, Antonio Gomes, Marisa Wong, Emily Stephens, Tabitha Grace Royal, Dan Frenkel, Weikang Cai, C Ronald Kah. Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 21. 2023-05-15. PMID:37186836. |
epidemiological studies have indicated a strong connection between type 2 diabetes (t2d) and neurodegenerative disorders, especially alzheimer's disease (ad), linked via dysregulation of insulin signaling, i.e., insulin resistance. |
2023-05-15 |
2023-08-14 |
mouse |
| Mohsin Ali Khan, Zaw Ali Khan, Fouzia Shoeb, Ghizal Fatima, Rizwan Hasan Khan, Mohammad M Kha. Role of de novo lipogenesis in inflammation and insulin resistance in alzheimer's disease. International journal of biological macromolecules. 2023-05-15. PMID:37187418. |
role of de novo lipogenesis in inflammation and insulin resistance in alzheimer's disease. |
2023-05-15 |
2023-08-14 |
Not clear |
| Mohsin Ali Khan, Zaw Ali Khan, Fouzia Shoeb, Ghizal Fatima, Rizwan Hasan Khan, Mohammad M Kha. Role of de novo lipogenesis in inflammation and insulin resistance in alzheimer's disease. International journal of biological macromolecules. 2023-05-15. PMID:37187418. |
patients with alzheimer's disease (ad) display both peripheral tissue and brain insulin resistance, the later could be a potential risk factor for cognitive dysfunction. |
2023-05-15 |
2023-08-14 |
Not clear |
| Jeffrey Fesse. Cure of Alzheimer's Dementia in Many Patients by Using Intranasal Insulin to Augment an Inadequate Counter-Reaction, Edaravone to Scavenge ROS, and 1 or 2 Other Drugs to Address Affected Brain Cells. Journal of clinical medicine. vol 12. issue 9. 2023-05-14. PMID:37176592. |
cure of alzheimer's dementia in many patients by using intranasal insulin to augment an inadequate counter-reaction, edaravone to scavenge ros, and 1 or 2 other drugs to address affected brain cells. |
2023-05-14 |
2023-08-14 |
Not clear |
| Jie Wang, Pengzhan Shuang, Zhao Li, Longbiao Zhao, Xiuli Wang, Peng Li. Association of insulin resistance with delirium and CSF biomarkers of Alzheimer's disease in elderly patients with hip fracture. Aging clinical and experimental research. 2023-05-11. PMID:37166562. |
association of insulin resistance with delirium and csf biomarkers of alzheimer's disease in elderly patients with hip fracture. |
2023-05-11 |
2023-08-14 |
Not clear |
| Rui Liu, Lei Zhang, Hao Yo. Insulin Resistance and Impaired Branched-Chain Amino Acid Metabolism in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-05-01. PMID:37125547. |
insulin resistance and impaired branched-chain amino acid metabolism in alzheimer's disease. |
2023-05-01 |
2023-08-14 |
Not clear |
| Montse Guardiola, Gerard Muntané, Iris Martínez, Lourdes Martorell, Josefa Girona, Daiana Ibarretxe, Núria Plana, María J Bullido, Elisabet Vilella, Josep Ribalt. Metabolic Overlap between Alzheimer's Disease and Metabolic Syndrome Identifies the International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108578. |
metabolic overlap between alzheimer's disease and metabolic syndrome identifies the alzheimer's disease (ad) and type 2 diabetes mellitus (t2dm) share metabolic alterations such as abnormal insulin and lipid metabolism and have some common genetic factors such as |
2023-04-28 |
2023-08-14 |
Not clear |
| Hsin-Chung Lin, Chi-Hsiang Chung, Lih-Chyang Chen, Jui-Yang Wang, Chien-Chou Chen, Kuo-Yang Huang, Ming-Hang Tsai, Wu-Chien Chien, Hsin-An Li. Pioglitazone use increases risk of Alzheimer's disease in patients with type 2 diabetes receiving insulin. Scientific reports. vol 13. issue 1. 2023-04-24. PMID:37095270. |
pioglitazone use increases risk of alzheimer's disease in patients with type 2 diabetes receiving insulin. |
2023-04-24 |
2023-08-14 |
Not clear |
| Hsin-Chung Lin, Chi-Hsiang Chung, Lih-Chyang Chen, Jui-Yang Wang, Chien-Chou Chen, Kuo-Yang Huang, Ming-Hang Tsai, Wu-Chien Chien, Hsin-An Li. Pioglitazone use increases risk of Alzheimer's disease in patients with type 2 diabetes receiving insulin. Scientific reports. vol 13. issue 1. 2023-04-24. PMID:37095270. |
this study further investigated the relationship between pioglitazone use and the risk of developing alzheimer's disease (ad) in patients newly diagnosed with t2dm, and examined the potential impact of insulin use on this association. |
2023-04-24 |
2023-08-14 |
Not clear |
| Xin Cao, John P Thyfaul. Exercise drives metabolic integration between muscle, adipose and liver metabolism and protects against aging-related diseases. Experimental gerontology. 2023-04-21. PMID:37085127. |
as a result, older age is recognized as a major factor in the global metabolic disorders epidemic (insulin resistance, type 2 diabetes (t2d), fatty liver) and chronic disease conditions (alzheimer's, cardiovascular disease, etc.). |
2023-04-21 |
2023-08-14 |
Not clear |
| Nazia Siddiqui, Javed Ali, Suhel Parvez, Abul Kalam Najmi, Mohd Akhta. Neuroprotective Role of DPP-4 Inhibitor Linagliptin Against Neurodegeneration, Neuronal Insulin Resistance and Neuroinflammation Induced by Intracerebroventricular Streptozotocin in Rat Model of Alzheimer's Disease. Neurochemical research. 2023-04-20. PMID:37079222. |
neuroprotective role of dpp-4 inhibitor linagliptin against neurodegeneration, neuronal insulin resistance and neuroinflammation induced by intracerebroventricular streptozotocin in rat model of alzheimer's disease. |
2023-04-20 |
2023-08-14 |
rat |
| Van Nguyen, Peter Thomas, Sarah Pemberton, Alice Babin, Cassidy Noonan, Riley Weaver, William A Banks, Elizabeth M Rhe. Central nervous system insulin signaling can influence the rate of insulin influx into brain. Fluids and barriers of the CNS. vol 20. issue 1. 2023-04-19. PMID:37076875. |
insulin bbb interactions are impaired in alzheimer's disease (ad) and cns insulin resistance is widely prevalent in ad. |
2023-04-19 |
2023-08-14 |
Not clear |
| Mairéad Sullivan, Fernando Fernandez-Aranda, Lucía Camacho-Barcia, Andrew Harkin, Simone Macrì, Bernat Mora-Maltas, Susana Jiménez-Murcia, Aet O'Leary, Angela Maria Ottomana, Martina Presta, David Slattery, Samantha Scholtz, Jeffrey C Glenno. Insulin and Disorders of Behavioural Flexibility. Neuroscience and biobehavioral reviews. 2023-04-14. PMID:37059405. |
indeed, insulin resistance is reported to generate anxious, perseverative phenotypes in animal models, with the type 2 diabetes medication metformin proving to be beneficial for disorders including alzheimer's disease. |
2023-04-14 |
2023-08-14 |
Not clear |
| Alev Duygu Acun, Deniz Kantar, Hakan Er, Orhan Erkan, Narin Derin, Piraye Yargıcogl. Investigation of Cyclo-Z Therapeutic Effect on Insulin Pathway in Alzheimer's Rat Model: Biochemical and Electrophysiological Parameters. Molecular neurobiology. 2023-04-05. PMID:37020122. |
investigation of cyclo-z therapeutic effect on insulin pathway in alzheimer's rat model: biochemical and electrophysiological parameters. |
2023-04-05 |
2023-08-14 |
rat |
| Violina Kakoty, Sarathlal Kc, Shobha Kumari, Chih-Hao Yang, Sunil Kumar Dubey, Amirhossein Sahebkar, Prashant Kesharwani, Rajeev Taliya. Brain insulin resistance linked Alzheimer's and Parkinson's disease pathology: An undying implication of epigenetic and autophagy modulation. Inflammopharmacology. 2023-03-23. PMID:36952096. |
brain insulin resistance linked alzheimer's and parkinson's disease pathology: an undying implication of epigenetic and autophagy modulation. |
2023-03-23 |
2023-08-14 |
Not clear |
| Gilda E Ennis, Tobey J Betthauser, Rebecca Langhough Koscik, Nathaniel A Chin, Bradley T Christian, Sanjay Asthana, Sterling C Johnson, Barbara B Bendli. The relationship of insulin resistance and diabetes to tau PET SUVR in middle-aged to older adults. Alzheimer's research & therapy. vol 15. issue 1. 2023-03-18. PMID:36932429. |
insulin resistance (ir) and type 2 diabetes have been found to increase the risk for alzheimer's clinical syndrome in epidemiologic studies but have not been associated with tau tangles in neuropathological research and have been inconsistently associated with cerebrospinal fluid p-tau181. |
2023-03-18 |
2023-08-14 |
Not clear |
| Jagan A Pillai, James Bena, Lynn Bekris, Nandan Kodur, Takhar Kasumov, James B Leverenz, Sangeeta R Kashya. Metabolic syndrome biomarkers relate to rate of cognitive decline in MCI and dementia stages of Alzheimer's disease. Alzheimer's research & therapy. vol 15. issue 1. 2023-03-17. PMID:36927447. |
the relationship between biomarkers of metabolic syndrome and insulin resistance, plasma triglyceride/hdl cholesterol (tg/hdl-c) ratio, on the rate of cognitive decline in mild cognitive impairment (mci) and dementia stages of alzheimer's disease (ad) is unknown. |
2023-03-17 |
2023-08-14 |
Not clear |
| Priyadarshi Prajjwal, Shahnaz Asharaf, Dhruvi Makhanasa, Aishwarya Yamparala, Halla Tariq, Soumya Aleti, Srikanth Gadam, Neel Vor. Association of Alzheimer's dementia with oral bacteria, vitamin B12, folate, homocysteine levels, and insulin resistance along with its pathophysiology, genetics, imaging, and biomarkers. Disease-a-month : DM. 2023-03-17. PMID:36931946. |
association of alzheimer's dementia with oral bacteria, vitamin b12, folate, homocysteine levels, and insulin resistance along with its pathophysiology, genetics, imaging, and biomarkers. |
2023-03-17 |
2023-08-14 |
Not clear |
| Priyadarshi Prajjwal, Shahnaz Asharaf, Dhruvi Makhanasa, Aishwarya Yamparala, Halla Tariq, Soumya Aleti, Srikanth Gadam, Neel Vor. Association of Alzheimer's dementia with oral bacteria, vitamin B12, folate, homocysteine levels, and insulin resistance along with its pathophysiology, genetics, imaging, and biomarkers. Disease-a-month : DM. 2023-03-17. PMID:36931946. |
this review article explores the potential pathogenesis of alzheimer's disease, focusing on the effects of derangements in the levels of vitamin b12, folate, and homocysteine, as well as the impact of oral bacteria causing periodontitis and insulin resistance, and their relationship to alzheimer's. |
2023-03-17 |
2023-08-14 |
Not clear |