| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chia-Fang Lee, Tanya T Paull, Maria D Perso. Proteome-wide detection and quantitative analysis of irreversible cysteine oxidation using long column UPLC-pSRM. Journal of proteome research. vol 12. issue 10. 2014-05-06. PMID:23964713. |
this fourier transform mass spectrometry (ft-ms) approach enabled detection and quantitation of ataxia telangiectasia mutated (atm) complex cysteine sulfoxidation states using skyline ms1 filtering. |
2014-05-06 |
2023-08-12 |
Not clear |
| Wei Zhou, Mao Sun, Guang-Hui Li, Yong-Zhong Wu, Ying Wang, Fu Jin, Yun-Yun Zhang, Li Yang, Dong-Lin Wan. Activation of the phosphorylation of ATM contributes to radioresistance of glioma stem cells. Oncology reports. vol 30. issue 4. 2014-04-29. PMID:23846672. |
furthermore, activated ataxia telangiectasia mutated (atm) is essential for the activation of downstream effector kinases, such as checkpoint kinase 2 (chk2) and p53 which mainly contribute to the proper regulation of ir-induced arrest in the g1 phase. |
2014-04-29 |
2023-08-12 |
Not clear |
| Shoichi Kubota, Yasunori Fukumoto, Kenichi Ishibashi, Shuhei Soeda, Sho Kubota, Ryuzaburo Yuki, Yuji Nakayama, Kazumasa Aoyama, Noritaka Yamaguchi, Naoto Yamaguch. Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage. The Journal of biological chemistry. vol 289. issue 9. 2014-04-25. PMID:24421316. |
activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (atm) protein without dna damage. |
2014-04-25 |
2023-08-12 |
Not clear |
| Shoichi Kubota, Yasunori Fukumoto, Kenichi Ishibashi, Shuhei Soeda, Sho Kubota, Ryuzaburo Yuki, Yuji Nakayama, Kazumasa Aoyama, Noritaka Yamaguchi, Naoto Yamaguch. Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage. The Journal of biological chemistry. vol 289. issue 9. 2014-04-25. PMID:24421316. |
mimosine treatment activates ataxia telangiectasia mutated (atm)/ataxia telangiectasia and rad3-related (atr)-mediated checkpoint signaling without inducing dna damage. |
2014-04-25 |
2023-08-12 |
Not clear |
| b' S Santini, V Stagni, R Giambruno, G Fianco, A Di Benedetto, M Mottolese, M Pellegrini, D Baril\\xc3\\xa. ATM kinase activity modulates ITCH E3-ubiquitin ligase activity. Oncogene. vol 33. issue 9. 2014-04-24. PMID:23435430.' |
ataxia telangiectasia mutated (atm) kinase, a central regulator of the dna damage response, regulates the activity of several e3-ubiquitin ligases, and the ubiquitination-proteasome system is a consistent target of atm. |
2014-04-24 |
2023-08-12 |
mouse |
| b' S Santini, V Stagni, R Giambruno, G Fianco, A Di Benedetto, M Mottolese, M Pellegrini, D Baril\\xc3\\xa. ATM kinase activity modulates ITCH E3-ubiquitin ligase activity. Oncogene. vol 33. issue 9. 2014-04-24. PMID:23435430.' |
our data identify itch as a novel component of the atm-dependent signaling pathway and suggest that the impairment of the correct functionality of itch caused by atm deficiency may contribute to the complex clinical features linked to ataxia telangiectasia. |
2014-04-24 |
2023-08-12 |
mouse |
| Liping Liang, Ji Zhu, Nicholas G Zaorsky, Yun Deng, Xingzhong Wu, Yong Liu, Fangqi Liu, Guoxiang Cai, Weilie Gu, Lijun Shen, Zhen Zhan. MicroRNA-223 enhances radiation sensitivity of U87MG cells in vitro and in vivo by targeting ataxia telangiectasia mutated. International journal of radiation oncology, biology, physics. vol 88. issue 4. 2014-04-24. PMID:24606854. |
ataxia telangiectasia mutated (atm) protein is important in the dna damage response because it repairs radiation-induced damage in cancers. |
2014-04-24 |
2023-08-12 |
Not clear |
| Yu Huang, Lu Yang, Jianchun Wang, Fan Yang, Ying Xiao, Rongjun Xia, Xianhou Yuan, Mingshan Ya. Twelve novel Atm mutations identified in Chinese ataxia telangiectasia patients. Neuromolecular medicine. vol 15. issue 3. 2014-04-15. PMID:23807571. |
twelve novel atm mutations identified in chinese ataxia telangiectasia patients. |
2014-04-15 |
2023-08-12 |
Not clear |
| Yu Huang, Lu Yang, Jianchun Wang, Fan Yang, Ying Xiao, Rongjun Xia, Xianhou Yuan, Mingshan Ya. Twelve novel Atm mutations identified in Chinese ataxia telangiectasia patients. Neuromolecular medicine. vol 15. issue 3. 2014-04-15. PMID:23807571. |
this disease is caused by mutations of the ataxia telangiectasia mutated (atm) gene. |
2014-04-15 |
2023-08-12 |
Not clear |
| Hanan Khoury-Haddad, Noga Guttmann-Raviv, Inbal Ipenberg, David Huggins, Anand D Jeyasekharan, Nabieh Ayou. PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 7. 2014-04-15. PMID:24550317. |
interestingly, this recruitment is independent of the ddr sensor ataxia telangiectasia mutated (atm), but dependent on poly (adp-ribose) polymerase 1 (parp1), which adp ribosylates kdm4d after damage. |
2014-04-15 |
2023-08-12 |
Not clear |
| Oleg Alekseev, Kelly Donovan, Jane Azizkhan-Cliffor. Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis. Investigative ophthalmology & visual science. vol 55. issue 2. 2014-04-14. PMID:24370835. |
inhibition of ataxia telangiectasia mutated (atm) kinase suppresses herpes simplex virus type 1 (hsv-1) keratitis. |
2014-04-14 |
2023-08-12 |
Not clear |
| Oleg Alekseev, Kelly Donovan, Jane Azizkhan-Cliffor. Inhibition of ataxia telangiectasia mutated (ATM) kinase suppresses herpes simplex virus type 1 (HSV-1) keratitis. Investigative ophthalmology & visual science. vol 55. issue 2. 2014-04-14. PMID:24370835. |
this study examined ataxia telangiectasia mutated (atm), an apical kinase in the host dna damage response, as a potential new target for the treatment of hk. |
2014-04-14 |
2023-08-12 |
Not clear |
| Kaoru O Yoshiyama, Junya Kobayashi, Nobuo Ogita, Minako Ueda, Seisuke Kimura, Hisaji Maki, Masaaki Umed. ATM-mediated phosphorylation of SOG1 is essential for the DNA damage response in Arabidopsis. EMBO reports. vol 14. issue 9. 2014-04-11. PMID:23907539. |
here we report that sog1 is phosphorylated in response to dna damage, and that this phosphorylation is mediated by the sensor kinase ataxia telangiectasia mutated (atm). |
2014-04-11 |
2023-08-12 |
Not clear |
| Ping-I Lin, Po-Hsiu Kuo, Chia-Hsiang Chen, Jer-Yuarn Wu, Susan S-F Gau, Yu-Yu Wu, Shih-Kai Li. Runs of homozygosity associated with speech delay in autism in a taiwanese han population: evidence for the recessive model. PloS one. vol 8. issue 8. 2014-04-08. PMID:23977206. |
this region contains the npat and atm genes associated with ataxia telangiectasia characterized by language impairment; the cul5 (culin 5) gene in the same region may modulate the neuronal migration process related to language functions. |
2014-04-08 |
2023-08-12 |
Not clear |
| Xiaofei E, George Savidis, Christopher R Chin, Shixia Wang, Shan Lu, Abraham L Brass, Timothy F Kowali. A novel DDB2-ATM feedback loop regulates human cytomegalovirus replication. Journal of virology. vol 88. issue 4. 2014-04-08. PMID:24335308. |
finally, a novel, infection-associated feedback loop between ddb2 and ataxia telangiectasia mutated (atm) was observed in infected cells. |
2014-04-08 |
2023-08-12 |
human |
| Vivek Vikram Singh, Dipanjan Dutta, Mairaj Ahmed Ansari, Sujoy Dutta, Bala Chandra. Kaposi's sarcoma-associated herpesvirus induces the ATM and H2AX DNA damage response early during de novo infection of primary endothelial cells, which play roles in latency establishment. Journal of virology. vol 88. issue 5. 2014-04-08. PMID:24352470. |
phosphorylation of representative ddr-associated proteins, such as ataxia telangiectasia mutated (atm) and h2ax, was induced as early as 30 min (0.5 h) postinfection and persisted during in vitro kshv latency. |
2014-04-08 |
2023-08-12 |
Not clear |
| Paulo M G Rodrigues, Paulius Grigaravicius, Martina Remus, Gabriel R Cavalheiro, Anielle L Gomes, Maurício Rocha-Martins, Mauricio R Martins, Lucien Frappart, David Reuss, Peter J McKinnon, Andreas von Deimling, Rodrigo A P Martins, Pierre-Olivier Frappar. Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye. PloS one. vol 8. issue 7. 2014-04-01. PMID:23935957. |
mutations in nbn or atm result in nijmegen breakage syndrome and ataxia telangiectasia. |
2014-04-01 |
2023-08-12 |
mouse |
| Serah Choi, Christopher J Bakkenis. Brd4 shields chromatin from ATM kinase signaling storms. Science signaling. vol 6. issue 293. 2014-04-01. PMID:24045152. |
upon activation, ataxia telangiectasia mutated (atm) kinase rapidly phosphorylates hundreds of proteins, setting off chaotic signaling storms from areas of damaged chromatin. |
2014-04-01 |
2023-08-12 |
Not clear |
| César Eduardo Monterrubio Ledezma, Alfredo Corona Rivera, Jorge Román Corona Rivera, Lourdes Jocelyn Rodríguez Casillas, Juan Hernández Rocha, Patricio Barros Nuñez, Lucina Bobadilla Morale. [Ataxia telangiectasia. Diagnosis and follow-up in 4 cases]. Gaceta medica de Mexico. vol 149. issue 4. 2014-03-31. PMID:23999637. |
ataxia telangiectasia (at) is a chromosomal instability syndrome with autosomal recessive inheritance, it is caused by more than 500 mutations of the atm gene, which is involved in the cellular response to dna damage. |
2014-03-31 |
2023-08-12 |
Not clear |
| Liutao Du, Michael E Jung, Robert Damoiseaux, Gladys Completo, Francesca Fike, Jin-Mo Ku, Shareef Nahas, Cijing Piao, Hailiang Hu, Richard A Gatt. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Molecular therapy : the journal of the American Society of Gene Therapy. vol 21. issue 9. 2014-03-26. PMID:23774824. |
the activity of these two compounds was confirmed in cells derived from ataxia telangiectasia (a-t) patients with three different types of nonsense mutation in the atm gene. |
2014-03-26 |
2023-08-12 |
Not clear |