| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zainunisha Arieff, Mandeep Kaur, Hajirah Gameeldien, Lize van der Merwe, Vladimir B Baji. 5-HTTLPR polymorphism: analysis in South African autistic individuals. Human biology. vol 82. issue 3. 2011-03-03. PMID:20649385. |
the use of selective serotonin reuptake inhibitors (ssris) has a positive effect on treating some symptoms of autism. |
2011-03-03 |
2023-08-12 |
human |
| Catherine E Hagan, John F Neumaier, James O Schen. Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes. Journal of neuroscience methods. vol 193. issue 1. 2011-01-21. PMID:20713085. |
altered serotonin (5-ht) signaling is implicated in several neuropsychiatric disorders, including depression, anxiety, obsessive-compulsive disorder, and autism. |
2011-01-21 |
2023-08-12 |
mouse |
| Karen L Jones, Ryan M Smith, Kristin S Edwards, Bennet Givens, Michael R Tilley, David Q Beversdor. Combined effect of maternal serotonin transporter genotype and prenatal stress in modulating offspring social interaction in mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 6. 2011-01-11. PMID:20470877. |
results indicated that prenatal stress and reduced serotonin transporter expression of the dam may have the combined effect of producing changes in social interaction and social interest in the offspring consistent with those observed in autism spectrum disorder. |
2011-01-11 |
2023-08-12 |
mouse |
| D Q Ma, R Rabionet, I Konidari, J Jaworski, H N Cukier, H H Wright, R K Abramson, J R Gilbert, M L Cuccaro, M A Pericak-Vance, E R Marti. Association and gene-gene interaction of SLC6A4 and ITGB3 in autism. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 2. 2010-12-20. PMID:19588468. |
studies point to possible links between autism and two serotonin related genes: slc6a4 and itgb3 with a sex-specific genetic effect and interaction between the genes. |
2010-12-20 |
2023-08-12 |
Not clear |
| Trisha L Self, LaDonna S Hale, Daiquirie Crumrin. Pharmacotherapy and children with autism spectrum disorder: a tutorial for speech-language pathologists. Language, speech, and hearing services in schools. vol 41. issue 3. 2010-10-21. PMID:20543026. |
the purpose of this tutorial is to provide speech-language pathologists (slps) with general information regarding the most commonly prescribed medications for children with autism spectrum disorder (asd; e.g., central nervous system stimulants, noradrenergic reuptake inhibitors, alpha-2 adrenergic agonists, antipsychotics, anticonvulsants, selective serotonin reuptake inhibitors, benzodiazepines) in regard to their mechanism of action, behaviors treated, and potential side effects. |
2010-10-21 |
2023-08-12 |
Not clear |
| Gabriel S Dichter, Linmarie Sikich, Steve Mahorney, Jennifer N Felder, Kristen S L Lam, Lauren Turner-Brown, James Bodfis. fMRI tracks reductions in repetitive behaviors in autism: two case studies. Neurocase. vol 16. issue 4. 2010-10-08. PMID:20178033. |
in this proof-of-principle study, functional magnetic resonance imaging (fmri) was used to examine brain activity during an oddball task in two high-functioning males with autism before and after 12 weeks of treatment with citalopram, a selective serotonin reuptake inhibitor. |
2010-10-08 |
2023-08-12 |
human |
| Taro Endo, Hideaki Kitamura, Ryu Tamura, Jun Egawa, Takuro Sugai, Naoki Fukui, Yutaro Suzuki, Toshiyuki Somey. 5-HTTLPR polymorphism influences prefrontal neurochemical metabolites in autism spectrum disorder. Psychiatry research. vol 183. issue 2. 2010-09-16. PMID:20619617. |
we investigated whether the promoter region of the serotonin transporter gene (5-httlpr) polymorphism influenced neurochemical metabolism in 26 individuals with autism spectrum disorder. |
2010-09-16 |
2023-08-12 |
Not clear |
| Nouchine Hadjikhan. Serotonin, pregnancy and increased autism prevalence: is there a link? Medical hypotheses. vol 74. issue 5. 2010-08-18. PMID:20018455. |
serotonin, pregnancy and increased autism prevalence: is there a link? |
2010-08-18 |
2023-08-12 |
Not clear |
| Justin H G Williams, David I Perrett, Gordon D Waiter, Stephen Peche. Differential effects of tryptophan depletion on emotion processing according to face direction. Social cognitive and affective neuroscience. vol 2. issue 4. 2010-06-23. PMID:18985132. |
reading facial emotion is disrupted by both psychopathology, such as autism, and altered function of neurotransmitter, such as serotonin. |
2010-06-23 |
2023-08-12 |
Not clear |
| Justin H G Williams, David I Perrett, Gordon D Waiter, Stephen Peche. Differential effects of tryptophan depletion on emotion processing according to face direction. Social cognitive and affective neuroscience. vol 2. issue 4. 2010-06-23. PMID:18985132. |
these changes could be adaptive in a threatening context and markedly affect empathic function in conditions associated with impaired serotonin function, such as depression and autism. |
2010-06-23 |
2023-08-12 |
Not clear |
| Alexander Kolevzon, Jeffrey H Newcorn, Lauren Kryzak, William Chaplin, Dryden Watner, Eric Hollander, Christopher J Smith, Edwin H Cook, Jeremy M Silverma. Relationship between whole blood serotonin and repetitive behaviors in autism. Psychiatry research. vol 175. issue 3. 2010-03-16. PMID:20044143. |
relationship between whole blood serotonin and repetitive behaviors in autism. |
2010-03-16 |
2023-08-12 |
human |
| Alexander Kolevzon, Jeffrey H Newcorn, Lauren Kryzak, William Chaplin, Dryden Watner, Eric Hollander, Christopher J Smith, Edwin H Cook, Jeremy M Silverma. Relationship between whole blood serotonin and repetitive behaviors in autism. Psychiatry research. vol 175. issue 3. 2010-03-16. PMID:20044143. |
this study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. |
2010-03-16 |
2023-08-12 |
human |
| D I Zafeiriou, A Ververi, E Vargiam. The serotonergic system: its role in pathogenesis and early developmental treatment of autism. Current neuropharmacology. vol 7. issue 2. 2010-03-05. PMID:19949574. |
evidence for the role of serotonin in autism emerges from neuropathological, imaging and genetic studies. |
2010-03-05 |
2023-08-12 |
Not clear |
| Erik J Mulder, George M Anderson, Ramses F J Kemperman, Alida Oosterloo-Duinkerken, Ruud B Minderaa, Ido P Kem. Urinary excretion of 5-hydroxyindoleacetic acid, serotonin and 6-sulphatoxymelatonin in normoserotonemic and hyperserotonemic autistic individuals. Neuropsychobiology. vol 61. issue 1. 2010-03-01. PMID:19923863. |
a substantial proportion of individuals with autism have elevated levels of platelet serotonin (5-ht). |
2010-03-01 |
2023-08-12 |
Not clear |
| Kazuhiko Nakamura, Yoshimoto Sekine, Yasuomi Ouchi, Masatsugu Tsujii, Etsuji Yoshikawa, Masami Futatsubashi, Kenji J Tsuchiya, Genichi Sugihara, Yasuhide Iwata, Katsuaki Suzuki, Hideo Matsuzaki, Shiro Suda, Toshiro Sugiyama, Nori Takei, Norio Mor. Brain serotonin and dopamine transporter bindings in adults with high-functioning autism. Archives of general psychiatry. vol 67. issue 1. 2010-01-20. PMID:20048223. |
brain serotonin and dopamine transporter bindings in adults with high-functioning autism. |
2010-01-20 |
2023-08-12 |
Not clear |
| Lis West, Susan H Brunssen, Julee Waldro. Review of the evidence for treatment of children with autism with selective serotonin reuptake inhibitors. Journal for specialists in pediatric nursing : JSPN. vol 14. issue 3. 2009-10-30. PMID:19614827. |
review of the evidence for treatment of children with autism with selective serotonin reuptake inhibitors. |
2009-10-30 |
2023-08-12 |
Not clear |
| Lis West, Susan H Brunssen, Julee Waldro. Review of the evidence for treatment of children with autism with selective serotonin reuptake inhibitors. Journal for specialists in pediatric nursing : JSPN. vol 14. issue 3. 2009-10-30. PMID:19614827. |
to review the potential role of serotonin dysregulation in autism and the efficacy of selective serotonin reuptake inhibitors (ssris) in treating core deficits and associated symptoms of autism in children. |
2009-10-30 |
2023-08-12 |
Not clear |
| B M Anderson, N C Schnetz-Boutaud, J Bartlett, A M Wotawa, H H Wright, R K Abramson, M L Cuccaro, J R Gilbert, M A Pericak-Vance, J L Haine. Examination of association of genes in the serotonin system to autism. Neurogenetics. vol 10. issue 3. 2009-09-16. PMID:19184136. |
numerous studies have suggested that variation in peripheral and central metabolism of serotonin (5-hydroxytryptamine) may play a role in the pathophysiology of autism. |
2009-09-16 |
2023-08-12 |
Not clear |
| S S Moy, J J Nadler, N B Young, R J Nonneman, A W Grossman, D L Murphy, A J D'Ercole, J N Crawley, T R Magnuson, J M Laude. Social approach in genetically engineered mouse lines relevant to autism. Genes, brain, and behavior. vol 8. issue 2. 2009-06-26. PMID:19016890. |
autism has been associated with altered serotonin levels and polymorphisms in slc6a4 (sert), the serotonin transporter gene. |
2009-06-26 |
2023-08-12 |
mouse |
| Dubravka Hranilović, Zorana Bujas-Petković, Maja Tomicić, Tatjana Bordukalo-Niksić, Sofia Blazević, Lipa Cicin-Sai. Hyperserotonemia in autism: activity of 5HT-associated platelet proteins. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 4. 2009-06-09. PMID:19221690. |
disturbances in serotonin (5ht) neurotransmission have been indicated as biological substrates in several neuropsychiatric disorders including autism. |
2009-06-09 |
2023-08-12 |
human |