Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D E Lewis, D S Ng Tang, X Wang, C Kozinet. Costimulatory pathways mediate monocyte-dependent lymphocyte apoptosis in HIV. Clinical immunology (Orlando, Fla.). vol 90. issue 3. 1999-04-13. PMID:10075859. |
cd8(+) t cell apoptosis correlated with fewer cd4(+) t cells, but not the level of viremia. |
1999-04-13 |
2023-08-12 |
Not clear |
B Murphy, C C Magee, S I Alexander, A M Waaga, H W Snoeck, J P Vella, C B Carpenter, M H Sayeg. Inhibition of allorecognition by a human class II MHC-derived peptide through the induction of apoptosis. The Journal of clinical investigation. vol 103. issue 6. 1999-04-02. PMID:10079107. |
these data demonstrate that synthetic peptides derived from highly conserved regions of the class ii mhc alpha chain can alter cd4(+) t-lymphocyte alloimmune responses in vitro, and this effect is mediated by the induction of apoptosis in activated t cells. |
1999-04-02 |
2023-08-12 |
mouse |
L L Perry, K Feilzer, S Hughes, H D Caldwel. Clearance of Chlamydia trachomatis from the murine genital mucosa does not require perforin-mediated cytolysis or Fas-mediated apoptosis. Infection and immunity. vol 67. issue 3. 1999-03-12. PMID:10024585. |
these results fail to support cd4(+) t-cell-mediated apoptosis or cd8(+) t-cell-mediated cytotoxicity as being critical to the clearance of c. trachomatis mopn urogenital infections. |
1999-03-12 |
2023-08-12 |
mouse |
M S Hu, J D Schwartzman, G R Yeaman, J Collins, R Seguin, I A Khan, L H Kaspe. Fas-FasL interaction involved in pathogenesis of ocular toxoplasmosis in mice. Infection and immunity. vol 67. issue 2. 1999-03-09. PMID:9916110. |
intraocular inflammation, fas and fasl expression on lymphocytes and on ocular tissues, the occurrence of apoptosis, and the frequency of cd8(+) and cd4(+) t cells in the infected eyes were analyzed in c57bl/6 (b6) mice. |
1999-03-09 |
2023-08-12 |
mouse |
M S Hu, J D Schwartzman, G R Yeaman, J Collins, R Seguin, I A Khan, L H Kaspe. Fas-FasL interaction involved in pathogenesis of ocular toxoplasmosis in mice. Infection and immunity. vol 67. issue 2. 1999-03-09. PMID:9916110. |
apoptosis of inflammatory cells and cells in ocular tissues was seen, and a greater frequency of cd8(+) than cd4(+) t cells was observed in the infected eyes. |
1999-03-09 |
2023-08-12 |
mouse |
I Arbel, E Chezen, O Abramsky, T Karpati, H Ovadia, R Mizrachi-Koll, D Karussi. Linomide induces apoptotic death of cortical CD4/CD8 double positive thymocytes and thymic atrophy by a corticosteroid-independent pathway. Clinical immunology (Orlando, Fla.). vol 90. issue 1. 1999-03-05. PMID:9884358. |
thymuses from these animals were examined for size and cellularity and immunohistopathologically for the detection of apoptosis and for the expression of the markers cd4 and cd8. |
1999-03-05 |
2023-08-12 |
mouse |
S Reinberger, M Spring, T Nisslein, C Stahl-Hennig, G Hunsmann, U Dittme. Kinetics of lymphocyte apoptosis in macaques infected with different simian immunodeficiency viruses or simian/human immunodeficiency hybrid viruses. Clinical immunology (Orlando, Fla.). vol 90. issue 1. 1999-03-05. PMID:9884363. |
furthermore, lymphocyte apoptosis in infected macaques was associated with impaired proliferative responses of helper t-cells and with cd4 cell depletion. |
1999-03-05 |
2023-08-12 |
human |
S R Bartz, M Emerma. Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8. Journal of virology. vol 73. issue 3. 1999-03-04. PMID:9971775. |
apoptosis contributes to the loss of cd4 cells during human immunodeficiency virus type 1 (hiv-1) infection. |
1999-03-04 |
2023-08-12 |
human |
S R Bartz, M Emerma. Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8. Journal of virology. vol 73. issue 3. 1999-03-04. PMID:9971775. |
we found that hiv-1 lacking the env gene (hivdeltaenv) still induced apoptosis in t-cell lines and primary cd4 t cells. |
1999-03-04 |
2023-08-12 |
human |
T Hettmann, J DiDonato, M Karin, J M Leide. An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. The Journal of experimental medicine. vol 189. issue 1. 1999-02-25. PMID:9874571. |
perhaps more unexpectedly, double positive (cd4(+)cd8(+); dp) thymocytes from the mikappab-alpha mice were resistant to alpha-cd3-mediated apoptosis in vivo. |
1999-02-25 |
2023-08-12 |
mouse |
G Zauli, D Gibellini, P Secchiero, H Dutartre, D Olive, S Capitani, Y Collett. Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway. Blood. vol 93. issue 3. 1999-02-18. PMID:9920849. |
human immunodeficiency virus type 1 nef protein sensitizes cd4(+) t lymphoid cells to apoptosis via functional upregulation of the cd95/cd95 ligand pathway. |
1999-02-18 |
2023-08-12 |
human |
I Cremer, V Vieillard, E De Maeye. Interferon-beta-induced human immunodeficiency virus resistance in CD34(+) human hematopoietic progenitor cells: correlation with a down-regulation of CCR-5 expression. Virology. vol 253. issue 2. 1999-02-17. PMID:9918882. |
the ifn-beta-transduction of tf-1 cells resulted in resistance to infection with hiv-lai, as shown by the selective survival of ifn-beta-transduced cd4(+) cells and the protection against hiv-induced apoptosis. |
1999-02-17 |
2023-08-12 |
human |
T Kurita-Ochiai, K Fukushima, K Ochia. Lipopolysaccharide stimulates butyric acid-induced apoptosis in human peripheral blood mononuclear cells. Infection and immunity. vol 67. issue 1. 1999-01-28. PMID:9864191. |
annexin v binding experiments with fractionated subpopulations of pbmc in flow cytometory revealed that lps accelerated the butyric acid-induced cd3(+)-t-cell apoptosis followed by similar levels of both cd4(+)- and cd8(+)-t-cell apoptosis. |
1999-01-28 |
2023-08-12 |
human |
T Kurita-Ochiai, K Fukushima, K Ochia. Lipopolysaccharide stimulates butyric acid-induced apoptosis in human peripheral blood mononuclear cells. Infection and immunity. vol 67. issue 1. 1999-01-28. PMID:9864191. |
these data suggest that lps, in combination with butyric acid, potentiates cd3(+) pbmc t-cell apoptosis and plays a role in the apoptotic depletion of cd4(+) and cd8(+) cells. |
1999-01-28 |
2023-08-12 |
human |
E Rapaport, C R Casella, Ikl, F Mustafa, D Isaak, T H Finke. Mapping of HIV-1 determinants of apoptosis in infected T cells. Virology. vol 252. issue 2. 1999-01-28. PMID:9878620. |
we used flow cytometry to concurrently analyze infection and apoptosis of the cd4(+) cem t cell line and human peripheral blood mononuclear cells (pbmc). |
1999-01-28 |
2023-08-12 |
human |
L Wang, J J Chen, B B Gelman, R Konig, M W Cloy. A novel mechanism of CD4 lymphocyte depletion involves effects of HIV on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 1. 1999-01-21. PMID:9886395. |
a novel mechanism of cd4 lymphocyte depletion involves effects of hiv on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors. |
1999-01-21 |
2023-08-12 |
mouse |
L Wang, J J Chen, B B Gelman, R Konig, M W Cloy. A novel mechanism of CD4 lymphocyte depletion involves effects of HIV on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors. Journal of immunology (Baltimore, Md. : 1950). vol 162. issue 1. 1999-01-21. PMID:9886395. |
apoptosis did not occur after secondary signaling through some other receptors (cd26, cd4, cd45, and hla class i) or in hiv-exposed resting cd8+ lymphocytes signaled through the homing receptors. |
1999-01-21 |
2023-08-12 |
mouse |
A Kalinkovich, Z Weisman, Z Greenberg, J Nahmias, S Eitan, M Stein, Z Bentwic. Decreased CD4 and increased CD8 counts with T cell activation is associated with chronic helminth infection. Clinical and experimental immunology. vol 114. issue 3. 1999-01-14. PMID:9844052. |
the main findings in the 'new' eth group in comparison with the non-ethiopian controls were: (i) decreased cd4 and increased cd8 lymphocyte counts; (ii) elevated levels of activated t cells (cd3, cd4 and cd8) expressing hla-dr; (iii) decreased levels of 'naive' cd4+ cells (cd45ra+), with increased levels of 'memory' cd4+ cells (cd45ro+); (iv) decreased numbers of cd28+ cd8+ lymphocytes; (v) marked increase in lymphocyte apoptosis. |
1999-01-14 |
2023-08-12 |
Not clear |
T W McCloskey, S Bakshi, S Than, P Arman, S Pahw. Immunophenotypic analysis of peripheral blood mononuclear cells undergoing in vitro apoptosis after isolation from human immunodeficiency virus-infected children. Blood. vol 92. issue 11. 1999-01-05. PMID:9834228. |
when percent lymphocyte apoptosis follow- ing culture was examined independently with lymphocyte subsets in fresh blood, apoptosis was negatively correlated with the percentage of cd4 cells, but not with specific cd4 t-cell subsets. |
1999-01-05 |
2023-08-12 |
human |
Z Szondy, H Lecoeur, L Fesus, M L Gougeo. All-trans retinoic acid inhibition of anti-CD3-induced T cell apoptosis in human immunodeficiency virus infection mostly concerns CD4 T lymphocytes and is mediated via regulation of CD95 ligand expression. The Journal of infectious diseases. vol 178. issue 5. 1998-12-10. PMID:9780248. |
all-trans retinoic acid inhibition of anti-cd3-induced t cell apoptosis in human immunodeficiency virus infection mostly concerns cd4 t lymphocytes and is mediated via regulation of cd95 ligand expression. |
1998-12-10 |
2023-08-12 |
human |