| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Szondy, H Lecoeur, L Fesus, M L Gougeo. All-trans retinoic acid inhibition of anti-CD3-induced T cell apoptosis in human immunodeficiency virus infection mostly concerns CD4 T lymphocytes and is mediated via regulation of CD95 ligand expression. The Journal of infectious diseases. vol 178. issue 5. 1998-12-10. PMID:9780248. |
phenotypic characterization of t cell subsets prevented from anti-cd3-induced apoptosis by tra revealed a more potent effect on cd4 t cells. |
1998-12-10 |
2023-08-12 |
human |
| C Berndt, B Möpps, S Angermüller, P Gierschik, P H Kramme. CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 21. 1998-11-12. PMID:9770524. |
therefore, we investigated whether cd4 and cxcr4 mediate gp120-induced apoptosis. |
1998-11-12 |
2023-08-12 |
human |
| C Berndt, B Möpps, S Angermüller, P Gierschik, P H Kramme. CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 21. 1998-11-12. PMID:9770524. |
significantly, apoptosis was exclusively observed in cd4(+) but not in cd8(+) t cells, and apoptosis triggered via cxcr4 was inhibited by stromal cell-derived factor-1, the natural cxcr4 ligand. |
1998-11-12 |
2023-08-12 |
human |
| A Asada, Y Zhao, S Kondo, M Iwat. Induction of thymocyte apoptosis by Ca2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation. The Journal of biological chemistry. vol 273. issue 43. 1998-11-12. PMID:9774466. |
glucocorticoids appear to participate in apoptosis of unselected cd4(+)cd8(+) thymocytes. |
1998-11-12 |
2023-08-12 |
Not clear |
| E Holznagel, R Hofmann-Lehmann, C M Leutenegger, K Allenspach, S Huettner, U Forster, E Niederer, H Joller, B J Willett, U Hummel, G L Rossi, J Schüpbach, H Lut. The role of in vitro-induced lymphocyte apoptosis in feline immunodeficiency virus infection: correlation with different markers of disease progression. Journal of virology. vol 72. issue 11. 1998-11-05. PMID:9765447. |
the frequency of in vitro-induced apoptosis was inversely correlated with the cd4(+) cell count (p = 0. |
1998-11-05 |
2023-08-12 |
human |
| H Chen, Y K Yip, I George, M Tyorkin, E Salik, K Sperbe. Chronically HIV-1-infected monocytic cells induce apoptosis in cocultured T cells. Journal of immunology (Baltimore, Md. : 1950). vol 161. issue 8. 1998-11-04. PMID:9780201. |
pretreatment with 5145, a human polyclonal anti-gp120 ab that recognizes the cd4 binding region, as well as with an anti-fas ligand mab blocked apoptosis in cd4+ t cells but not in cd8+ t cells. |
1998-11-04 |
2023-08-12 |
human |
| J C Rathmell, S Fournier, B C Weintraub, J P Allison, C C Goodno. Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. The Journal of experimental medicine. vol 188. issue 4. 1998-10-07. PMID:9705947. |
chronic exposure to self-antigens desensitizes b cell antigen receptor (bcr) signaling on anergic b cells so that they are not stimulated into clonal expansion by cd4(+) t cells but instead are eliminated by fas (cd95)-induced apoptosis. |
1998-10-07 |
2023-08-12 |
Not clear |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid t-cell-line-expressing wild-type and mutated cd4 receptors. |
1998-10-07 |
2023-08-12 |
human |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
we have previously shown that the presence of the cd4 cytoplasmic tail is critical for human immunodeficiency virus (hiv)-induced apoptosis (j. corbeil, m. tremblay, and d. d. richman, j. exp. |
1998-10-07 |
2023-08-12 |
human |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
we have pursued our investigation of the role of the cd4 transduction pathway in hiv-induced apoptosis. |
1998-10-07 |
2023-08-12 |
human |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
apoptosis was prevented when cd4 truncated at residue 402 was expressed; however, cells expressing mutated receptors that do not associate with p56(lck) (mutated at the dicysteine motif and truncated at residue 418) but which conserved proximal domains of the cytoplasmic tail underwent apoptosis like wild-type cd4. |
1998-10-07 |
2023-08-12 |
human |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
initial signaling through the cd4 receptor played a major role in the sensitization of hiv-infected t cells to undergo apoptosis. |
1998-10-07 |
2023-08-12 |
human |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
incubation of hiv-infected cells with monoclonal antibody (mab) 13b8-2, which binds to cd4 in a region critical for dimerization of the receptor, prevented apoptosis without inhibiting hiv replication. |
1998-10-07 |
2023-08-12 |
human |
| L Moutouh, J Estaquier, D D Richman, J Corbei. Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors. Journal of virology. vol 72. issue 10. 1998-10-07. PMID:9733846. |
these observations demonstrate that cd4 signaling mediates hiv-induced apoptosis by a mechanism independent of fas-fas ligand interaction, does not require p56(lck) signaling, and may involve a critical region for cd4 dimerization. |
1998-10-07 |
2023-08-12 |
human |
| T J Liegler, W Yonemoto, T Elbeik, E Vittinghoff, S P Buchbinder, W C Green. Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors. The Journal of infectious diseases. vol 178. issue 3. 1998-09-29. PMID:9728534. |
long-term nonprogressors (ltnp) and seronegative controls had levels of spontaneous apoptosis significantly lower than those for recent seroconverters who had cd4 cell counts similar to those of nonprogressors but with a high likelihood of disease progression. |
1998-09-29 |
2023-08-12 |
human |
| T J Liegler, W Yonemoto, T Elbeik, E Vittinghoff, S P Buchbinder, W C Green. Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors. The Journal of infectious diseases. vol 178. issue 3. 1998-09-29. PMID:9728534. |
these findings demonstrate that increased lymphocyte apoptosis is evident prior to cd4 t cell decline and that ltnp are relatively resistant to the factors that induce accentuated levels of spontaneous but not mitogen-induced cell death. |
1998-09-29 |
2023-08-12 |
human |
| S P Aries, K Weyrich, B Schaaf, F Hansen, R H Dennin, K Dalhof. Early T-cell apoptosis and Fas expression during antiretroviral therapy in individuals infected with human immunodeficiency virus-1. Scandinavian journal of immunology. vol 48. issue 1. 1998-09-23. PMID:9714415. |
several lines of evidence suggest that fas-mediated apoptosis is involved in the cd4 t-cell depletion in human immunodeficiency virus-1 (hiv-1) infection. |
1998-09-23 |
2023-08-12 |
human |
| S P Aries, K Weyrich, B Schaaf, F Hansen, R H Dennin, K Dalhof. Early T-cell apoptosis and Fas expression during antiretroviral therapy in individuals infected with human immunodeficiency virus-1. Scandinavian journal of immunology. vol 48. issue 1. 1998-09-23. PMID:9714415. |
the levels of cd4 and cd8 t cells with early apoptosis were increased comparably in hiv-1-infected individuals. |
1998-09-23 |
2023-08-12 |
human |
| S P Aries, K Weyrich, B Schaaf, F Hansen, R H Dennin, K Dalhof. Early T-cell apoptosis and Fas expression during antiretroviral therapy in individuals infected with human immunodeficiency virus-1. Scandinavian journal of immunology. vol 48. issue 1. 1998-09-23. PMID:9714415. |
despite elevated cd4 t cell counts, no decline in early t-cell apoptosis could be detected during the first 8 weeks of art. |
1998-09-23 |
2023-08-12 |
human |
| S P Aries, K Weyrich, B Schaaf, F Hansen, R H Dennin, K Dalhof. Early T-cell apoptosis and Fas expression during antiretroviral therapy in individuals infected with human immunodeficiency virus-1. Scandinavian journal of immunology. vol 48. issue 1. 1998-09-23. PMID:9714415. |
fas expression on cd4 and cd8 t cells was reduced after initiation of art; this was independent of the cd4 t-cell trend and indicates that the immediate cd4 t-cell expansion during art is probably not the result of a decreased rate of early apoptosis among peripheral blood cd4 t cells. |
1998-09-23 |
2023-08-12 |
human |