| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Hafe. Recent advances in clinical/molecular andrology. Archives of andrology. vol 40. issue 3. 1998-06-11. PMID:9583357. |
the interaction of gp120 with cd4 receptor plays a role in syncytium formation, apoptosis and cd4 cell deletion in human immunodeficiency virus (hiv) infection. |
1998-06-11 |
2023-08-12 |
human |
| S Fournel, E Robinet, N Bonnefoy-Bérard, O Assossou, M Flacher, H Waldmann, G Bismuth, J P Revillar. A noncomitogenic CD2R monoclonal antibody induces apoptosis of activated T cells by a CD95/CD95-L-dependent pathway. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 9. 1998-05-21. PMID:9574534. |
however, p56lck activation is not sufficient to trigger apoptosis, because other cd2r and cd4 mabs that activate p56lck do not induce apoptosis. |
1998-05-21 |
2023-08-12 |
Not clear |
| T W McCloskey, N Oyaizu, S Bakshi, R Kowalski, N Kohn, S Pahw. CD95 expression and apoptosis during pediatric HIV infection: early upregulation of CD95 expression. Clinical immunology and immunopathology. vol 87. issue 1. 1998-05-18. PMID:9576008. |
in this study of peripheral blood lymphocytes from hiv-infected children, classified according to cdc immunologic categories, we found that the percentage of cd4 and cd8 t cells expressing cd95 and the percentage of lymphocytes undergoing apoptosis were increased in children with hiv infection and were greater in children from immunologic category iii as compared to those in category i. |
1998-05-18 |
2023-08-12 |
Not clear |
| I S Hassan, B A Bannister, A Akbar, W Weir, M Bofil. A study of the immunology of the chronic fatigue syndrome: correlation of immunologic parameters to health dysfunction. Clinical immunology and immunopathology. vol 87. issue 1. 1998-05-18. PMID:9576011. |
expression of the costimulatory receptor cd28 in cd8 cells was significantly reduced, and the apoptosis repressor ratio of bcl-2/bax in both cd4 and cd8 was increased in patients (p < 0.05). |
1998-05-18 |
2023-08-12 |
Not clear |
| H E Porritt, K L Anderson, R K Suniara, E J Jenkinson, J J Owe. Cellular interactions in the thymus regulate the protein kinase C signaling pathway. European journal of immunology. vol 28. issue 4. 1998-05-13. PMID:9565359. |
thus, phorbol 12-myristate 13-acetate (pma) causes a pkc-dependent down-regulation of cd4 expression and induces apoptosis in isolated thymocytes but has little effect on thymocytes maintained within intact thymic lobes or in reaggregate lobes containing purified thymocytes with either thymic or non-thymic stromal cells. |
1998-05-13 |
2023-08-12 |
Not clear |
| M Karmochkine, C Parizot, V Calvez, A Coutellier, S Herson, P Debré, G Gorocho. Susceptibility of peripheral blood mononuclear cells to apoptosis is correlated to plasma HIV load. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. vol 17. issue 5. 1998-05-12. PMID:9562044. |
to quantify spontaneous and activation-induced apoptosis in peripheral blood mononuclear cells (pbmc) of hiv-infected patients and to look for correlations between pbmc apoptosis levels, stages of hiv disease, cd4 count, and plasma viral load. |
1998-05-12 |
2023-08-12 |
Not clear |
| R T Gandhi, B K Chen, S E Straus, J K Dale, M J Lenardo, D Baltimor. HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism. The Journal of experimental medicine. vol 187. issue 7. 1998-05-08. PMID:9529327. |
infection by hiv-plap of peripheral blood mononuclear cells (pbmcs) and t cell lines leads to rapid depletion of cd4(+) t cells and induction of apoptosis. |
1998-05-08 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
i. superantigen-activated cd8 cells induce unidirectional fas-mediated apoptosis of antigen-activated cd4 cells. |
1998-04-30 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
stimulation of mature cd4 cells through the tcr induces cellular activation and expansion that are often followed by clonal elimination by a form of apoptosis termed activation-induced cell death. |
1998-04-30 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
this process of cd4 cell apoptosis is generally thought to reflect clonal suicide and to be independent of other cell types. |
1998-04-30 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
suppression by cd8 cells reflects their ability to induce cd4 cell apoptosis via ligation of fas. |
1998-04-30 |
2023-08-12 |
Not clear |
| A Noble, G A Pestano, H Canto. Suppression of immune responses by CD8 cells. I. Superantigen-activated CD8 cells induce unidirectional Fas-mediated apoptosis of antigen-activated CD4 cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 2. 1998-04-30. PMID:9551888. |
moreover, although activated cd8 cells that express fas ligand and fas eliminate cd4 cells through a fas-dependent mechanism, they are themselves resistant to fas-dependent apoptosis. |
1998-04-30 |
2023-08-12 |
Not clear |
| W G Telford, S Y Nam, E R Podack, R A Mille. CD30-regulated apoptosis in murine CD8 T cells after cessation of TCR signals. Cellular immunology. vol 182. issue 2. 1998-04-21. PMID:9514701. |
this "agonist withdrawal" cell death occurred largely within the cd8 t cell subset, with cd4 cells showing lower levels of apoptosis. |
1998-04-21 |
2023-08-12 |
Not clear |
| E Ledru, H Lecoeur, S Garcia, T Debord, M L Gougeo. Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 7. 1998-04-21. PMID:9531275. |
to determine whether increased t cell apoptosis in hiv-infected patients contributes to alterations in cytokine synthesis, we performed single-cell analysis of type 1 and type 2 cytokine production by cd4 and cd8 t cells, simultaneously with detection of apoptosis. |
1998-04-21 |
2023-08-12 |
Not clear |
| E Ledru, H Lecoeur, S Garcia, T Debord, M L Gougeo. Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 7. 1998-04-21. PMID:9531275. |
this gradient was detected in both cd4 and cd8 subsets, as well as in control donors and hiv-infected patients, in whom the susceptibility to apoptosis of il-2 and ifn-gamma producers was increased compared with controls. |
1998-04-21 |
2023-08-12 |
Not clear |
| S A Stohlman, C C Bergmann, M T Lin, D J Cua, D R Hinto. CTL effector function within the central nervous system requires CD4+ T cells. Journal of immunology (Baltimore, Md. : 1950). vol 160. issue 6. 1998-03-26. PMID:9510193. |
however, these cells rapidly undergo apoptosis, indicating that expression of ctl effector function with the parenchyma of the cns is cd4 dependent. |
1998-03-26 |
2023-08-12 |
mouse |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
cd4 regulates susceptibility to fas ligand- and tumor necrosis factor-mediated apoptosis. |
1998-03-24 |
2023-08-12 |
human |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
immediately after cd4 cross-linking, cd4+ t cells are rendered susceptible to apoptosis mediated by tnf or fasl. |
1998-03-24 |
2023-08-12 |
human |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
after cd4 activation, pkc regulates susceptibility to apoptosis mediated by fasl but not the induction of susceptibility to tnf-dependent apoptosis. |
1998-03-24 |
2023-08-12 |
human |
| A Algeciras, D H Dockrell, D H Lynch, C V Pay. CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis. The Journal of experimental medicine. vol 187. issue 5. 1998-03-24. PMID:9480981. |
moreover, significant differences between cd3 and cd4 activation were observed with regards to the kinetics of induction of cd4+ t cell susceptibility to fasl- and tnf-mediated apoptosis. |
1998-03-24 |
2023-08-12 |
human |