Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M G Cifone, E Alesse, L Di Marzio, B Ruggeri, F Zazzeroni, S Moretti, G Famularo, S M Steinberg, E Vullo, C De Simon. Effect of L-carnitine treatment in vivo on apoptosis and ceramide generation in peripheral blood lymphocytes from AIDS patients. Proceedings of the Association of American Physicians. vol 109. issue 2. 1997-06-03. PMID:9069583. |
l-carnitine administration has been shown to induce a strong reduction in the percentage of both cd4 and cd8 cells undergoing apoptosis. |
1997-06-03 |
2023-08-12 |
Not clear |
L Di Marzio, E Alesse, P Roncaioli, P Muzi, S Moretti, S Marcellini, G Amicosante, C De Simone, M G Cifon. Influence of L-carnitine on CD95 cross-lining-induced apoptosis and ceramide generation in human cell lines: correlation with its effects on purified acidic and neutral sphingomyelinases in vitro. Proceedings of the Association of American Physicians. vol 109. issue 2. 1997-06-03. PMID:9069584. |
recently, we examined the effects of a short-term (5-days) intravenous l-carnitine (6 g/die) treatment on apoptosis of cd4 and cd8 cells from 10 aids patients. |
1997-06-03 |
2023-08-12 |
human |
L Di Marzio, E Alesse, P Roncaioli, P Muzi, S Moretti, S Marcellini, G Amicosante, C De Simone, M G Cifon. Influence of L-carnitine on CD95 cross-lining-induced apoptosis and ceramide generation in human cell lines: correlation with its effects on purified acidic and neutral sphingomyelinases in vitro. Proceedings of the Association of American Physicians. vol 109. issue 2. 1997-06-03. PMID:9069584. |
without inducing side effects, l-carnitine administration has been shown to induce a potent reduction in the percentage of cells undergoing apoptosis, paralleled by a significant increase of cd4 an cd8 cells. |
1997-06-03 |
2023-08-12 |
human |
M Ito, M Watanabe, H Kamiya, M Sakura. Herpes simplex virus type 1 induces apoptosis in peripheral blood T lymphocytes. The Journal of infectious diseases. vol 175. issue 5. 1997-06-02. PMID:9129090. |
hsv-1 enhanced apoptosis in cd4 and hla-dr-positive t lymphocytes, but not in cd8 lymphocytes, when stimulated with pha. |
1997-06-02 |
2023-08-12 |
Not clear |
M Ito, M Watanabe, H Kamiya, M Sakura. Herpes simplex virus type 1 induces apoptosis in peripheral blood T lymphocytes. The Journal of infectious diseases. vol 175. issue 5. 1997-06-02. PMID:9129090. |
these results demonstrate that hsv-1 infection enhances apoptosis in activated t lymphocytes, particularly cd4 and hla-dr-positive t lymphocytes. |
1997-06-02 |
2023-08-12 |
Not clear |
M Ito, M Watanabe, H Kamiya, M Sakura. Herpes simplex virus type 1 induces apoptosis in peripheral blood T lymphocytes. The Journal of infectious diseases. vol 175. issue 5. 1997-06-02. PMID:9129090. |
apoptosis in cd4 helper t lymphocytes may account for immunosuppression and lymphocytopenia following hsv-1 infection. |
1997-06-02 |
2023-08-12 |
Not clear |
b' V N Ivanov, J Nikoli\\xc4\\x87-Zugi\\xc4\\x8. Transcription factor activation during signal-induced apoptosis of immature CD4(+)CD8(+) thymocytes. A protective role of c-Fos. The Journal of biological chemistry. vol 272. issue 13. 1997-05-02. PMID:9079686.' |
transcription factor activation during signal-induced apoptosis of immature cd4(+)cd8(+) thymocytes. |
1997-05-02 |
2023-08-12 |
mouse |
R D Malcomson, A R Clarke, A Peter, S B Coutts, S E Howie, D J Harriso. Apoptosis induced by gamma-irradiation, but not CD4 ligation, of peripheral T lymphocytes in vivo is p53-dependent. The Journal of pathology. vol 181. issue 2. 1997-04-21. PMID:9120720. |
apoptosis induced by gamma-irradiation, but not cd4 ligation, of peripheral t lymphocytes in vivo is p53-dependent. |
1997-04-21 |
2023-08-12 |
mouse |
R D Malcomson, A R Clarke, A Peter, S B Coutts, S E Howie, D J Harriso. Apoptosis induced by gamma-irradiation, but not CD4 ligation, of peripheral T lymphocytes in vivo is p53-dependent. The Journal of pathology. vol 181. issue 2. 1997-04-21. PMID:9120720. |
apoptosis was induced in vivo by ligation of cd4 on the cell surface following intravenous injection of anti-cd4 monoclonal antibody. |
1997-04-21 |
2023-08-12 |
mouse |
M L Gougeon, H Lecoeur, F Boudet, E Ledru, S Marzabal, S Boullier, R Roué, S Nagata, J Heene. Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 6. 1997-04-02. PMID:9058836. |
in an effort to understand some of the mechanisms used to limit lentivirus infection in african nonhuman primates, we compared apoptosis in infected humans vs chimpanzees in cd4 and cd8 t cells in relation with the expression of bcl-2 and fas molecules. |
1997-04-02 |
2023-08-12 |
human |
M L Gougeon, H Lecoeur, F Boudet, E Ledru, S Marzabal, S Boullier, R Roué, S Nagata, J Heene. Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 6. 1997-04-02. PMID:9058836. |
the intensity of apoptosis in cd4 and cd8 t cells from infected chimpanzees was very low, was not inducible by several tcr-dependent activators, and was comparable to that detected in noninfected chimpanzees. |
1997-04-02 |
2023-08-12 |
human |
M L Gougeon, H Lecoeur, F Boudet, E Ledru, S Marzabal, S Boullier, R Roué, S Nagata, J Heene. Lack of chronic immune activation in HIV-infected chimpanzees correlates with the resistance of T cells to Fas/Apo-1 (CD95)-induced apoptosis and preservation of a T helper 1 phenotype. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 6. 1997-04-02. PMID:9058836. |
interestingly, in contrast to the situation found in infected humans, fas ligation by agonistic abs or recombinant human fas ligand on cd4 and cd8 t cells from infected chimpanzees did not induce apoptosis in these subsets even when bcl-2 was down-regulated. |
1997-04-02 |
2023-08-12 |
human |
M Casamayor-Palleja, J Feuillard, J Ball, M Drew, I C MacLenna. Centrocytes rapidly adopt a memory B cell phenotype on co-culture with autologous germinal centre T cell-enriched preparations. International immunology. vol 8. issue 5. 1997-03-24. PMID:8671662. |
naive cd4(+) t cells, induced to express cd40 ligand, do not prevent gc b cells undergoing apoptosis. |
1997-03-24 |
2023-08-12 |
Not clear |
M Kameoka, T Kimura, Y H Zheng, S Suzuki, K Fujinaga, R B Luftig, K Ikut. Protease-defective, gp120-containing human immunodeficiency virus type 1 particles induce apoptosis more efficiently than does wild-type virus or recombinant gp120 protein in healthy donor-derived peripheral blood T cells. Journal of clinical microbiology. vol 35. issue 1. 1997-03-19. PMID:8968878. |
either preincubation of pbmc-ts with a fas antagonist or preincubation of l-2 particles with soluble cd4 blocked most of the apoptosis. |
1997-03-19 |
2023-08-12 |
human |
N Oyaizu, Y Adachi, F Hashimoto, T W McCloskey, N Hosaka, N Kayagaki, H Yagita, S Pahw. Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 5. 1997-03-11. PMID:9036997. |
monocytes express fas ligand upon cd4 cross-linking and induce cd4+ t cells apoptosis: a possible mechanism of bystander cell death in hiv infection. |
1997-03-11 |
2023-08-12 |
Not clear |
N Oyaizu, Y Adachi, F Hashimoto, T W McCloskey, N Hosaka, N Kayagaki, H Yagita, S Pahw. Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 5. 1997-03-11. PMID:9036997. |
we have previously demonstrated that cd4 cross-linking (cd4xl) performed in pbmc results in induction of t cell apoptosis in an accessory cell-dependent manner. |
1997-03-11 |
2023-08-12 |
Not clear |
M Iwata, Y Ohoka, T Kuwata, A Asad. Regulation of T cell apoptosis via T cell receptors and steroid receptors. Stem cells (Dayton, Ohio). vol 14. issue 6. 1997-03-03. PMID:8948021. |
less than 5% of immature cd4/cd8 double-positive (dp) thymocytes are positively selected to survive and differentiate into single-positive cd4 and cd8 t cells, while self-reactive dp thymocytes undergo apoptosis (negative selection). |
1997-03-03 |
2023-08-12 |
Not clear |
P Accornero, M Radrizzani, D Delia, F Gerosa, R Kurrle, M P Colomb. Differential susceptibility to HIV-GP120-sensitized apoptosis in CD4+ T-cell clones with different T-helper phenotypes: role of CD95/CD95L interactions. Blood. vol 89. issue 2. 1997-02-24. PMID:9002959. |
we show that only th1 clones are susceptible to hiv-gp120-sensitized apoptosis, although both types of clones express similar levels of cd4 and bind similar amounts of recombinant gp120. |
1997-02-24 |
2023-08-12 |
Not clear |
T W McCloskey, M Ott, E Tribble, S A Khan, S Teichberg, M O Paul, S Pahwa, E Verdin, N Chirmul. Dual role of HIV Tat in regulation of apoptosis in T cells. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 2. 1997-02-11. PMID:8993024. |
furthermore, cross-linking of cd4 molecules on t cells with gp160 and anti-gp160 ab showed markedly decreased apoptosis in tat101 cells compared with that induced in cells transfected with vector alone. |
1997-02-11 |
2023-08-12 |
Not clear |
G Zauli, S Capitan. HIV-1-related mechanisms of suppression of CD34+ hematopoietic progenitors. Pathobiology : journal of immunopathology, molecular and cellular biology. vol 64. issue 1. 1997-02-03. PMID:8856796. |
in fact, it has been shown that: (i) infection with hiv-1 and/or exposure of bone marrow accessory cells to envelope glycoprotein 120 (env gp 120) increases the production of inhibitory cytokines such as tumor necrosis factor alpha; (ii) a subset of cd34+ hematopoietic progenitor cells co-expresses the cd4 antigen and may be infected in vivo with hiv-1; (iii) hiv-1 virions or immune complexes containing env gp 120 are able to induce apoptosis of uninfected cd34+ hematopoietic progenitors. |
1997-02-03 |
2023-08-12 |
human |