| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jeremy T Miyauchi, Danling Chen, Matthew Choi, Jillian C Nissen, Kenneth R Shroyer, Snezana Djordevic, Ian C Zachary, David Selwood, Stella E Tsirk. Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression. Oncotarget. vol 7. issue 9. 2016-12-30. PMID:26755653. |
nrp1-deficient or eg00229-treated wild-type microglia exhibited a shift towards anti-tumorigenicity as evident by altered inflammatory marker profiles in vivo and decreased smad2/3 activation when conditioned in the presence of glioma-derived factors. |
2016-12-30 |
2023-08-13 |
mouse |
| Siqi Zhao, Jingyu Yang, Lixin Wang, Shengyi Peng, Jie Yin, Lina Jia, Xiaowei Yang, Zengqiang Yuan, Chunfu W. NF-κB Upregulates Type 5 Phosphodiesterase in N9 Microglial Cells: Inhibition by Sildenafil and Yonkenafil. Molecular neurobiology. vol 53. issue 4. 2016-12-26. PMID:26108184. |
importantly, sildenafil and yonkenafil significantly alleviated the death of sh-sy5y neuroblastoma cells and primary cortical neurons induced by the conditioned medium from activated microglia. |
2016-12-26 |
2023-08-13 |
Not clear |
| Manuela Meireles, Cláudia Marques, Sónia Norberto, Paulo Santos, Iva Fernandes, Nuno Mateus, Ana Faria, Conceição Calha. Anthocyanin effects on microglia M1/M2 phenotype: Consequence on neuronal fractalkine expression. Behavioural brain research. vol 305. 2016-12-16. PMID:26965567. |
sh-sy5y cell line was treated with the conditioned medium of microglia and with the anthocyanins alone. |
2016-12-16 |
2023-08-13 |
Not clear |
| Sinéad Kinsella, Hans-Georg König, Jochen H M Preh. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. eNeuro. vol 3. issue 2. 2016-12-13. PMID:27257617. |
bid-deficient primary mouse microglia showed reduced nf-κb signaling in response to tlr4 activation or exposure to conditioned medium derived from sod1 (g93a) expressing nsc-34 cells. |
2016-12-13 |
2023-08-13 |
mouse |
| Valentina Villa, Stefano Thellung, Alessandro Corsaro, Federica Novelli, Bruno Tasso, Luca Colucci-D'Amato, Elena Gatta, Michele Tonelli, Tullio Flori. Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells. Molecular neurobiology. vol 53. issue 1. 2016-11-02. PMID:25404089. |
conditioned medium from prp90-231-treated microglia induced in vitro cytotoxicity of a1 mesencephalic neurons, supporting the notion that soluble mediators released by activated microglia contributes to the neurodegeneration during prion diseases. |
2016-11-02 |
2023-08-13 |
Not clear |
| S Ruiz-Mendoza, H Macedo-Ramos, F A Santos, L C Quadros-de-Souza, M M Paiva, T C A Pinto, L M Teixeira, W Baetas-da-Cru. Streptococcus pneumoniae infection regulates expression of neurotrophic factors in the olfactory bulb and cultured olfactory ensheathing cells. Neuroscience. vol 317. 2016-10-24. PMID:26791522. |
moreover, we found that conditioned medium from infected oec cultures induced the expression of the pro-apoptotic protein cleaved-caspase-3 and an apparently continuous nuclear factor-kappa b (nf-κb) p65 activation in the n13 microglia. |
2016-10-24 |
2023-08-13 |
mouse |
| Kyu Suk Cho, Eun Joo Lee, Jung Nam Kim, Ji Woong Choi, Hahn Young Kim, Seol-Heui Han, Jong Hoon Ryu, Jae Hoon Cheong, Chan Young Shin, Kyoung Ja Kwo. Proteinase 3 Induces Neuronal Cell Death Through Microglial Activation. Neurochemical research. vol 40. issue 11. 2016-08-24. PMID:26349766. |
the conditioned media from activated microglia by pr3 was used for measuring the neurotoxic effects of pr3-stimulated microglia. |
2016-08-24 |
2023-08-13 |
rat |
| Kyu Suk Cho, Eun Joo Lee, Jung Nam Kim, Ji Woong Choi, Hahn Young Kim, Seol-Heui Han, Jong Hoon Ryu, Jae Hoon Cheong, Chan Young Shin, Kyoung Ja Kwo. Proteinase 3 Induces Neuronal Cell Death Through Microglial Activation. Neurochemical research. vol 40. issue 11. 2016-08-24. PMID:26349766. |
conditioned media from pr3-treated microglia induced neuronal cell death in a concentration dependent manner. |
2016-08-24 |
2023-08-13 |
rat |
| LiMei Qin, Ron Bouchard, Subbiah Pugazhenth. Regulation of cyclic AMP response element-binding protein during neuroglial interactions. Journal of neurochemistry. vol 136. issue 5. 2016-08-22. PMID:26677139. |
conditioned medium from the abeta (aβ)-activated microglia decreased creb phosphorylation and brain-derived neurotrophic factor promoter activity (47%), whereas the same medium induced (p < 0.01) the promoter of cxcl10, a chemokine, in npc-derived neuron-rich cultures. |
2016-08-22 |
2023-08-13 |
human |
| Yang Pan, Bo Shen, Qin Gao, Jun Zhu, Jingde Dong, Li Zhang, Yingdong Zhan. Caspase-1 inhibition attenuates activation of BV2 microglia induced by LPS-treated RAW264.7 macrophages. Journal of biomedical research. vol 30. issue 3. 2016-08-18. PMID:27533933. |
furthermore, the conditioned medium obtained from lps-treated raw264.7 macrophages activated bv2 microglia, stimulating the release of il-1β, il-6 and tnf-α from bv2 cells. |
2016-08-18 |
2023-08-13 |
Not clear |
| Yang Pan, Bo Shen, Qin Gao, Jun Zhu, Jingde Dong, Li Zhang, Yingdong Zhan. Caspase-1 inhibition attenuates activation of BV2 microglia induced by LPS-treated RAW264.7 macrophages. Journal of biomedical research. vol 30. issue 3. 2016-08-18. PMID:27533933. |
zyvad pretreatment markedly suppressed bv2 microglia activation induced by raw264.7 cells conditioned medium. |
2016-08-18 |
2023-08-13 |
Not clear |
| Qun Zhang, Lin Yuan, Qingrui Zhang, Yan Gao, Guangheng Liu, Meng Xiu, Xiang Wei, Zhen Wang, Dexiang Li. Resveratrol attenuates hypoxia-induced neurotoxicity through inhibiting microglial activation. International immunopharmacology. vol 28. issue 1. 2016-07-19. PMID:26225925. |
importantly, treating primary cortical neurons with conditioned medium (cm) from hypoxia-stimulated microglia induced neuronal apoptosis, which was reversed by cm co-treated with resveratrol. |
2016-07-19 |
2023-08-13 |
Not clear |
| Cyrill Bussy, Khuloud T Al-Jamal, Jorge Boczkowski, Sophie Lanone, Maurizio Prato, Alberto Bianco, Kostas Kostarelo. Microglia Determine Brain Region-Specific Neurotoxic Responses to Chemically Functionalized Carbon Nanotubes. ACS nano. vol 9. issue 8. 2016-07-11. PMID:26043308. |
when exposed to conditioned media from microglia enriched cultures exposed to mwnts, st-derived glial cultures secreted more no than fco-derived cells. |
2016-07-11 |
2023-08-13 |
rat |
| Feng Wang, Na Cui, Lijun Yang, Lin Shi, Qian Li, Gengshen Zhang, Jianliang Wu, Jun Zheng, Baohua Jia. Resveratrol Rescues the Impairments of Hippocampal Neurons Stimulated by Microglial Over-Activation In Vitro. Cellular and molecular neurobiology. vol 35. issue 7. 2016-06-24. PMID:25898934. |
conditioned medium (cm) from activated microglia treated by resveratrol directly protected primary cultured hippocampal neurons against lps-cm-induced neuronal death, and restored the inhibitory effects of lps-cm on dendrite sprouting and outgrowth. |
2016-06-24 |
2023-08-13 |
Not clear |
| Carolina A Moraes, Gabriel Santos, Tania Cristina Leite de Sampaio e Spohr, Joana C D'Avila, Flávia Regina Souza Lima, Claudia Farias Benjamim, Fernando A Bozza, Flávia Carvalho Alcantara Gome. Activated Microglia-Induced Deficits in Excitatory Synapses Through IL-1β: Implications for Cognitive Impairment in Sepsis. Molecular neurobiology. vol 52. issue 1. 2016-05-17. PMID:25257696. |
we treated neuronal cultures with conditioned medium derived from cultured astrocytes (acm) and microglia (mcm) that were either non-stimulated or stimulated with lipopolysaccharide (lps) to investigate the molecular mechanisms underlying synaptic deficits in sepsis. |
2016-05-17 |
2023-08-13 |
mouse |
| Hirohide Asai, Seiko Ikezu, Maya E Woodbury, Grant M S Yonemoto, Libin Cui, Tsuneya Ikez. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1. The American journal of pathology. vol 184. issue 3. 2016-04-28. PMID:24418258. |
furthermore, primary cultured mouse motor neurons showed axonal degeneration after transient expression of the ttbk1 gene or treatment with conditioned media derived from lipopolysaccharide-stimulated microglia; this was partially blocked by silencing of the endogenous ttbk1 gene in neurons. |
2016-04-28 |
2023-08-12 |
mouse |
| Kimberleve Rolón-Reyes, Yuriy V Kucheryavykh, Luis A Cubano, Mikhail Inyushin, Serguei N Skatchkov, Misty J Eaton, Jeffrey K Harrison, Lilia Y Kucheryavyk. Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway. PloS one. vol 10. issue 6. 2016-04-27. PMID:26098895. |
using western blot analysis, we found upregulation of proline rich tyrosine kinase 2 (pyk2) protein phosphorylated at tyr579/580 in glioma cells treated with microglia conditioned medium. |
2016-04-27 |
2023-08-13 |
mouse |
| Jenny Molet, Annie Mauborgne, Mickael Diallo, Vincent Armand, David Geny, Luis Villanueva, Yves Boucher, Michel Poh. Microglial Janus kinase/signal transduction and activator of transcription 3 pathway activity directly impacts astrocyte and spinal neuron characteristics. Journal of neurochemistry. vol 136. issue 1. 2016-04-25. PMID:26440453. |
purified rat primary microglia was stimulated with jak/stat3 classical activator interleukin-6 in the presence or absence of a selective stat3 inhibitor and rat primary astrocytes or spinal cord neurons were exposed to microglia conditioned media (cm). |
2016-04-25 |
2023-08-13 |
rat |
| Cayla M Duffy, Ce Yuan, Lauren E Wisdorf, Charles J Billington, Catherine M Kotz, Joshua P Nixon, Tammy A Butteric. Role of orexin A signaling in dietary palmitic acid-activated microglial cells. Neuroscience letters. vol 606. 2016-03-03. PMID:26306651. |
finally, we show hypothalamic neurons exposed to conditioned media from pa-challenged microglia have increased cell survival only when microglia were pretreated with oxa. |
2016-03-03 |
2023-08-13 |
Not clear |
| Matthew McMillin, Gabriel Frampton, Richard Tobin, Giuseppina Dusio, Jenny Smith, Hope Shin, Karen Newell-Rogers, Stephanie Grant, Sharon DeMorro. TGR5 signaling reduces neuroinflammation during hepatic encephalopathy. Journal of neurochemistry. vol 135. issue 3. 2016-02-10. PMID:26179031. |
lastly, treatment of the microglia cell line eoc-20 with conditioned media from betulinic acid-treated primary neurons decreased phagocytic activity and cytokine production. |
2016-02-10 |
2023-08-13 |
mouse |