| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mads Toustrup-Jensen, Bente Vilse. Interaction between the catalytic site and the A-M3 linker stabilizes E2/E2P conformational states of Na+,K+-ATPase. The Journal of biological chemistry. vol 280. issue 11. 2005-04-25. PMID:15574410. |
the rate of phosphorylation from atp was unaffected in ile(265) --> ala, indicating a lack of interference with the catalytic function in e(1)/e(1)p. the effects of mutations thr(267) --> ala, gly(271) --> ala, and gly(274) --> ala provide the first evidence in the literature of a relative stabilization of e(2)/e(2)p resulting from perturbation of the a-m3 linker region. |
2005-04-25 |
2023-08-12 |
Not clear |
| Tetsuo Asakura, Yasumoto Nakazaw. Structure and structural changes of the silk fibroin from Samia cynthia ricini using nuclear magnetic resonance spectroscopy. Macromolecular bioscience. vol 4. issue 3. 2005-04-21. PMID:15468207. |
the fast exchange with respect to the chemical shift between the helix and coil conformations was observed in the poly-ala region and the slow conformational change from alpha-helix to random coil was observed for the gly residue adjacent to the n-terminal ala residue of the poly-ala region. |
2005-04-21 |
2023-08-12 |
Not clear |
| Tetsuo Asakura, Yasumoto Nakazaw. Structure and structural changes of the silk fibroin from Samia cynthia ricini using nuclear magnetic resonance spectroscopy. Macromolecular bioscience. vol 4. issue 3. 2005-04-21. PMID:15468207. |
the torsion angles of several ala and gly residues in the model peptide, ggagggyggdgg(a)12gga-gdgygag, were determined by the conformation-dependent 13c chemical shifts, rotational echo double resonance (redor) and 2d spin-diffusion nmr methods. |
2005-04-21 |
2023-08-12 |
Not clear |
| Stacy A Overman, Priya Bondre, Nakul C Maiti, George J Thoma. Structural characterization of the filamentous bacteriophage PH75 from Thermus thermophilus by Raman and UV-resonance Raman spectroscopy. Biochemistry. vol 44. issue 8. 2005-04-18. PMID:15723554. |
gly, ala, ser), and because the occurrence of such motifs in alpha-helices is believed to thermostabilize interhelix associations via c(alpha)-h...o interactions [g. kleiger et al. |
2005-04-18 |
2023-08-12 |
Not clear |
| Fabrizia Brisdelli, Michele Saliola, Stefano Pascarella, Carla Luzi, Nicola Franceschini, Claudio Falcone, Filippo Martini, Argante Bozz. Kinetic properties of native and mutagenized isoforms of mitochondrial alcohol dehydrogenase III purified from Kluyveromyces lactis. Biochimie. vol 86. issue 9-10. 2005-04-14. PMID:15556281. |
these two residues, gly 225 and ala 274, were hypothesized to be involved in the enzyme discrimination between nad(h) and nadp(h). |
2005-04-14 |
2023-08-12 |
cat |
| Fabrizia Brisdelli, Michele Saliola, Stefano Pascarella, Carla Luzi, Nicola Franceschini, Claudio Falcone, Filippo Martini, Argante Bozz. Kinetic properties of native and mutagenized isoforms of mitochondrial alcohol dehydrogenase III purified from Kluyveromyces lactis. Biochimie. vol 86. issue 9-10. 2005-04-14. PMID:15556281. |
upon changing gly 225 to ala we produced an enzyme (mutant g225a) showing very little difference from the wild-type. |
2005-04-14 |
2023-08-12 |
cat |
| Luzia A Pando, Daniela D de Carvalho, Marcos H Toyama, Luciana Di Ciero, José C Novello, Sérgio F Pascholatti, Sérgio Marangon. Purification and characterization of a lectin from Crotalaria paulina seeds. The protein journal. vol 23. issue 7. 2005-04-14. PMID:15635935. |
the n-terminal amino acid sequence of crpl was identical to those of other lectins from the genus crotalaria, and amino acid composition showed high amounts of asx and glx, and was rich in gly, ala and ser, as also reported for lectins from other crotalaria species. |
2005-04-14 |
2023-08-12 |
human |
| Yukihiro Kimura, Naoki Mizusawa, Toshihiro Yamanari, Asako Ishii, Taka-aki On. Structural changes of D1 C-terminal alpha-carboxylate during S-state cycling in photosynthetic oxygen evolution. The Journal of biological chemistry. vol 280. issue 3. 2005-04-13. PMID:15542597. |
several bands for carboxylate symmetric stretching modes in an s(2)/s(1) ftir difference spectrum were affected by selective (13)c labeling of the alpha-carboxylate of ala with l-[1-(13)c]alanine, whereas most of the isotopic effects failed to be induced in a site-directed mutant in which ala-344 was replaced with gly. |
2005-04-13 |
2023-08-12 |
Not clear |
| David R Piper, William A Hinz, Chandra K Tallurri, Michael C Sanguinetti, Martin Tristani-Firouz. Regional specificity of human ether-a'-go-go-related gene channel activation and inactivation gating. The Journal of biological chemistry. vol 280. issue 8. 2005-04-08. PMID:15528201. |
to characterize the voltage sensor movement associated with herg activation and inactivation, we performed an ala scan of the 32 amino acids (gly(514)-tyr(545)) that comprise the s4 domain and the flanking s3-s4 and s4-s5 linkers. |
2005-04-08 |
2023-08-12 |
human |
| Yacine Abed, Nathalie Goyette, Guy Boivi. A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus. Antiviral therapy. vol 9. issue 4. 2005-04-06. PMID:15456089. |
the his274tyr and glu119gln mutants were rescued whereas the arg292lys and glu1l9 --> gly, val, ala or asp mutants could not be generated. |
2005-04-06 |
2023-08-12 |
Not clear |
| Yoshio Mori, Tamaki Okabayashi, Tetsuo Yamashita, Zijiang Zhao, Takaji Wakita, Kotaro Yasui, Futoshi Hasebe, Masayuki Tadano, Eiji Konishi, Kohji Moriishi, Yoshiharu Matsuur. Nuclear localization of Japanese encephalitis virus core protein enhances viral replication. Journal of virology. vol 79. issue 6. 2005-04-05. PMID:15731239. |
a mutant m4243 virus in which both gly(42) and pro(43) were replaced by ala was recovered by plasmid-based reverse genetics. |
2005-04-05 |
2023-08-12 |
mouse |
| Haydée Fukuda, Adriana Casas, Alcira Batll. Aminolevulinic acid: from its unique biological function to its star role in photodynamic therapy. The international journal of biochemistry & cell biology. vol 37. issue 2. 2005-03-29. PMID:15474973. |
two alternative routes for the formation of ala have been proposed: one involves the condensation of succinyl coa and glycine catalyzed by ala synthetase taking place in the mitochondria, and the second one is the so called 5-carbon route, occurring in the stroma of plastids. |
2005-03-29 |
2023-08-12 |
Not clear |
| Ilaria Bartalesi, Ivano Bertini, Giulia Di Rocco, Antonio Ranieri, Antonio Rosato, Murugendra Vanarotti, Paul R Vasos, Maria Silvia Viezzol. Protein stability and mutations in the axial methionine loop of a minimal cytochrome c. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. vol 9. issue 5. 2005-03-24. PMID:15175936. |
pro72 has been mutated to gly and ala to modify the range of allowed backbone conformations. |
2005-03-24 |
2023-08-12 |
Not clear |
| Yoshiki Matsumiya, Kouji Nishikawa, Hisae Aoshima, Kuniyo Inouye, Motoki Kub. Analysis of autodegradation sites of thermolysin and enhancement of its thermostability by modifying Leu155 at an autodegradation site. Journal of biochemistry. vol 135. issue 4. 2005-03-21. PMID:15115781. |
one of the sites was identified as gly(154)-leu(155), and leu(155) was substituted with various amino acids, x = ala, ser, phe, and gly, by site-directed mutagenesis. |
2005-03-21 |
2023-08-12 |
Not clear |
| Yoshiki Matsumiya, Kouji Nishikawa, Hisae Aoshima, Kuniyo Inouye, Motoki Kub. Analysis of autodegradation sites of thermolysin and enhancement of its thermostability by modifying Leu155 at an autodegradation site. Journal of biochemistry. vol 135. issue 4. 2005-03-21. PMID:15115781. |
the thermostability at 80 degrees c increased with the amino acid substitutions in the order of ala>phe>ser>gly>leu (wt tln). |
2005-03-21 |
2023-08-12 |
Not clear |
| Kazumi Kimura, Tomoyuki Numata, Yoshimitsu Kakuta, Makoto Kimur. Amino acids conserved at the C-terminal half of the ribonuclease T2 family contribute to protein stability of the enzymes. Bioscience, biotechnology, and biochemistry. vol 68. issue 8. 2005-03-18. PMID:15322360. |
taken together, it appeared that tyr(101), phe(102), ala(105), pro(125), gly(127), gly(144), leu(162), val(165), and phe(190) conserved in the rnase t2 family play an important role in the stability of the proteins. |
2005-03-18 |
2023-08-12 |
Not clear |
| Xiang-Qi Mu, Zhenghui G Jiang, Esther Bullit. Localization of a critical interface for helical rod formation of bacterial adhesion P-pili. Journal of molecular biology. vol 346. issue 1. 2005-03-11. PMID:15663923. |
using site-directed mutagenesis, ultrastructural analysis by electron cryomicroscopy, immunocytochemistry, and molecular modeling we show that residues 106-109 (asn, gly, ala, gly) are essential for assembly of native p-pilus filaments. |
2005-03-11 |
2023-08-12 |
Not clear |
| Svetlana V Smirnova, Irina I Torocheshnikova, Andrey A Formanovsky, Igor V Pletne. Solvent extraction of amino acids into a room temperature ionic liquid with dicyclohexano-18-crown-6. Analytical and bioanalytical chemistry. vol 378. issue 5. 2005-03-07. PMID:14747900. |
amino acids trp, gly, ala, leu are extracted efficiently from aqueous solution at ph 1.5-4.0 (lys and arg at ph 1.5-5.5) into the room temperature ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate (bmimpf(6)) with dicyclohexano-18-crown-6 (ce). |
2005-03-07 |
2023-08-12 |
Not clear |
| Svetlana V Smirnova, Irina I Torocheshnikova, Andrey A Formanovsky, Igor V Pletne. Solvent extraction of amino acids into a room temperature ionic liquid with dicyclohexano-18-crown-6. Analytical and bioanalytical chemistry. vol 378. issue 5. 2005-03-07. PMID:14747900. |
the ratio of amino acid to crown ether in the extracted species is 1:1 for cationic trp, leu, ala, and gly and to 1:2 for dicationic arg and lys. |
2005-03-07 |
2023-08-12 |
Not clear |
| Jian Guo Wu, Chun Hai Shi, Xiao Ming Zhang, Tomita Katsur. Genetic analysis of non-essential amino acid contents in rice (Oryza sativa L.) across environments. Hereditas. vol 141. issue 2. 2005-03-04. PMID:15660973. |
it was found that the content of non-essential amino acids including asp, ser, glu, gly and tyr were mainly controlled by genetic main effects, whereas the content of ala or pro was mainly affected by ge effects. |
2005-03-04 |
2023-08-12 |
Not clear |