Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Einar Sagstuen, Audun Sanderud, Eli O Hol. The solid-state radiation chemistry of simple amino acids, revisited. Radiation research. vol 162. issue 2. 2004-11-29. PMID:15387137. |
the solid-state radiation-induced free radical formation in simple amino acids like alpha-glycine (gly) and l-alpha-alanine (ala) has been the subject of investigations by epr spectroscopy since the late 1950s. |
2004-11-29 |
2023-08-12 |
human |
Einar Sagstuen, Audun Sanderud, Eli O Hol. The solid-state radiation chemistry of simple amino acids, revisited. Radiation research. vol 162. issue 2. 2004-11-29. PMID:15387137. |
the epr spectra from crystals of gly and ala generally are very complex due to the simultaneous trapping of several free radicals regardless of irradiation and observation temperatures. |
2004-11-29 |
2023-08-12 |
human |
Einar Sagstuen, Audun Sanderud, Eli O Hol. The solid-state radiation chemistry of simple amino acids, revisited. Radiation research. vol 162. issue 2. 2004-11-29. PMID:15387137. |
recently, radical formation in gly and ala after room-temperature irradiation has been reinvestigated in our laboratories using x-, k- and q-band epr and endor spectroscopy, combined with the endor-induced epr (eie) techniques as well as single-crystal and powder epr and endor spectrum simulations. |
2004-11-29 |
2023-08-12 |
human |
Einar Sagstuen, Audun Sanderud, Eli O Hol. The solid-state radiation chemistry of simple amino acids, revisited. Radiation research. vol 162. issue 2. 2004-11-29. PMID:15387137. |
several new radical products have been detected and characterized, most prominently the gly species h2n - c x h - cooh and the ala species h3+n - c x (ch3) - coo and h2n - c x (ch3) - cooh. |
2004-11-29 |
2023-08-12 |
human |
Masayuki Hanyu, Ryoji Yanagihara, Masaki Katoh, Shinji Hongo, Toshifumi Miyazawa, Takashi Yamad. Metal ion-binding ability of tetrapeptides containing alpha-aminoisobutyric acid. Journal of peptide science : an official publication of the European Peptide Society. vol 10. issue 3. 2004-11-24. PMID:15113087. |
liquid-liquid extraction of nine kinds of metal ions from aqueous layers to nonpolar organic layers with acyclic tetrapeptides, x-trp-xaa2-gly-xaa4-nh-ar (x = h or c6h5ch2oco (z), xaa2 = aib or gly, xaa4 = leu or ala, ar = phenyl or 3,5-dimethylphenyl) was examined using picrate as the anion of ion pairs. |
2004-11-24 |
2023-08-12 |
Not clear |
Robyn L O'Kane, Juan R Viña, Ian Simpson, Richard A Hawkin. Na+ -dependent neutral amino acid transporters A, ASC, and N of the blood-brain barrier: mechanisms for neutral amino acid removal. American journal of physiology. Endocrinology and metabolism. vol 287. issue 4. 2004-10-26. PMID:15165996. |
system a transports pro, ala, his, asn, ser, and gln; system asc transports ser, gly, met, val, leu, ile, cys, and thr; system n transports gln, his, ser, and asn; na+ -lnaa transports leu, ile, val, trp, tyr, phe, met, ala, his, thr, and gly. |
2004-10-26 |
2023-08-12 |
Not clear |
Thean Chor Leow, Raja Noor Zaliha Raja Abdul Rahman, Mahiran Basri, Abu Bakar Salle. High level expression of thermostable lipase from Geobacillus sp. strain T1. Bioscience, biotechnology, and biochemistry. vol 68. issue 1. 2004-10-25. PMID:14745170. |
instead of gly, ala was substituted as the first residue of the conserved pentapeptide gly-x-ser-x-gly. |
2004-10-25 |
2023-08-12 |
Not clear |
Artur Krezel, Wojciech Ba. Structure-function relationships in glutathione and its analogues. Organic & biomolecular chemistry. vol 1. issue 22. 2004-10-08. PMID:14664379. |
the results are presented of measurements of protonation constants (potentiometry and nmr), uv spectroscopic properties and redox potentials of gsh and its five analogues, which are modified at the c-terminal glycine residue (gammaglu-cys-x, x = gly, gly-nh2, gly-oet, ala, glu, ser). |
2004-10-08 |
2023-08-12 |
Not clear |
Saika Somjee, Lolie C Yu, Arthur F Hagar, James M Hemp. Diagnosis and characterization of Hb C/Hb Iowa: a rare but easily misidentified compound heterozygous condition. Hemoglobin. vol 28. issue 1. 2004-10-07. PMID:15008260. |
hb iowa is a rare hemoglobin (hb) variant with a gly --> ala substitution at position 119 of beta-globin. |
2004-10-07 |
2023-08-12 |
Not clear |
Christoph P Dieterle, Michael Conzelmann, Ulrich Linnemann, Martin R Berge. Detection of isolated tumor cells by polymerase chain reaction-restriction fragment length polymorphism for K-ras mutations in tissue samples of 199 colorectal cancer patients. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 10. issue 2. 2004-10-04. PMID:14760087. |
sequence analysis of tumor dna revealed that ggt (gly) was replaced by gat (asp; 35%), gtt (val; 32%), agt (ser; 13%), gct (ala; 10%), tgt (cys; 8%), and cgt (arg; 2%) for codon 12, and by gac (asp) as the only type of mutation for codon 13. |
2004-10-04 |
2023-08-12 |
Not clear |
Shin Saeng Lim, Yun Mi Song, Mi Hyang Jang, Yangmee Kim, Kyung-Soo Hahm, Song Yub Shi. Effects of two glycine residues in positions 13 and 17 of pleurocidin on structure and bacterial cell selectivity. Protein and peptide letters. vol 11. issue 1. 2004-10-01. PMID:14965277. |
in this study, the effect of two glycine residues in positions 13 and 17 of ple on structure and bacterial cell selectivity was investigated by gly-->ala substitution. |
2004-10-01 |
2023-08-12 |
Not clear |
Shin Saeng Lim, Yun Mi Song, Mi Hyang Jang, Yangmee Kim, Kyung-Soo Hahm, Song Yub Shi. Effects of two glycine residues in positions 13 and 17 of pleurocidin on structure and bacterial cell selectivity. Protein and peptide letters. vol 11. issue 1. 2004-10-01. PMID:14965277. |
ala-substitution (gly(13, 17)-->ala, gly13-->ala and gly17-->ala) in positions 13 and 17 of ple did not induce a significant change in antibacterial activity, but increased hemolytic activity. |
2004-10-01 |
2023-08-12 |
Not clear |
Shin Saeng Lim, Yun Mi Song, Mi Hyang Jang, Yangmee Kim, Kyung-Soo Hahm, Song Yub Shi. Effects of two glycine residues in positions 13 and 17 of pleurocidin on structure and bacterial cell selectivity. Protein and peptide letters. vol 11. issue 1. 2004-10-01. PMID:14965277. |
both gly(13, 17)-->ala and gly17-->ala substitution did not cause a remarkable change in alpha-helical content in sds micelles, while gly(13, 17)-->ala substitution caused a drastic increase in alpha-helical content. |
2004-10-01 |
2023-08-12 |
Not clear |
b' Nicolas Loiseau, Jean-Marie Gomis, J\\xc3\\xa9r\\xc3\\xb4me Santolini, Marcel Delaforge, Fran\\xc3\\xa7ois Andr\\xc3\\xa. Predicting the conformational states of cyclic tetrapeptides. Biopolymers. vol 69. issue 3. 2004-09-30. PMID:12833263.' |
the cyclo(gly)(4), cyclo(ala)(4), cyclo(sar)(4), and cyclo(sargly)(2) peptides were used to evaluate the prediction of the peptide backbone conformation, and the detailed conformational analysis of tentoxin, a natural phytotoxic cyclotetrapeptide in which n-alkylated peptide bonds alternate with regular secondary ones, was used to validate the computation of conformers proportions. |
2004-09-30 |
2023-08-12 |
Not clear |
Jorge A Vila, Héctor A Baldoni, Daniel R Ripoll, Avijit Ghosh, Harold A Scherag. Polyproline II helix conformation in a proline-rich environment: a theoretical study. Biophysical journal. vol 86. issue 2. 2004-09-20. PMID:14747311. |
for this purpose, we explored the formation of polyproline ii helices in proline-rich peptides with the sequences ac-(pro)(3)-x-(pro)(3)-gly-tyr-nh(2), with x = pro (ppp), ala (pap), gln (pqp), gly (pgp), and val (pvp), and ac-(pro)(3)-ala-ala-(pro)(3)-gly-tyr-nh(2) (paap), by using a theoretical approach that includes a solvent effect as well as cis <--> trans isomerization of the peptide groups and puckering conformations of the pyrrolidine ring of the proline residues. |
2004-09-20 |
2023-08-12 |
Not clear |
Jorge A Vila, Héctor A Baldoni, Daniel R Ripoll, Avijit Ghosh, Harold A Scherag. Polyproline II helix conformation in a proline-rich environment: a theoretical study. Biophysical journal. vol 86. issue 2. 2004-09-20. PMID:14747311. |
since (13)c chemical shifts have proven to be useful for identifying secondary-structure preferences in proteins and peptides, and because values of the dihedral angles (phi,psi) are the main determinants of their magnitudes, we have, therefore, computed the boltzmann-averaged (13)c chemical shifts for the guest residues in the pxp peptide (x = pro, ala, gln, gly, and val) with a combination of approaches, involving molecular mechanics, statistical mechanics, and quantum mechanics. |
2004-09-20 |
2023-08-12 |
Not clear |
David B McIntosh, Johannes D Clausen, David G Woolley, David H MacLennan, Bente Vilsen, Jens Peter Anderse. Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase. The Journal of biological chemistry. vol 279. issue 31. 2004-09-10. PMID:15133025. |
these mutations, as well as gly(626)--> ala, were inhibitory for atp binding in the presence of mg(2+) and for tight binding of the beta,gamma-bidentate chromium(iii) complex of atp. |
2004-09-10 |
2023-08-12 |
Not clear |
David B McIntosh, Johannes D Clausen, David G Woolley, David H MacLennan, Bente Vilsen, Jens Peter Anderse. Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase. The Journal of biological chemistry. vol 279. issue 31. 2004-09-10. PMID:15133025. |
mutants gly(626) --> ala, lys(684) --> met, asp(703) --> ala/ser/cys, and mutants with alteration to asp(707) exhibited very slow or negligible phosphorylation, making it possible to measure atp binding in the pseudo-transition state attained in the presence of both mg(2+) and ca(2+). |
2004-09-10 |
2023-08-12 |
Not clear |
David B McIntosh, Johannes D Clausen, David G Woolley, David H MacLennan, Bente Vilsen, Jens Peter Anderse. Roles of conserved P domain residues and Mg2+ in ATP binding in the ground and Ca2+-activated states of sarcoplasmic reticulum Ca2+-ATPase. The Journal of biological chemistry. vol 279. issue 31. 2004-09-10. PMID:15133025. |
under these conditions, atp binding was almost completely blocked in gly(626) --> ala and occurred with 12- and 7-fold reduced affinities in asp(703) --> ala and asp(707) --> cys, respectively, relative to the situation in the presence of mg(2+) without ca(2+), whereas in lys(684) --> met and asp(707) --> ser/asn the affinity was enhanced 14- and 3-5-fold, respectively. |
2004-09-10 |
2023-08-12 |
Not clear |
Karen Ochoa Lara, Carolina Godoy-Alcantar, Alexey V Eliseev, Anatoly K Yatsimirsk. Recognition of alpha-amino acid derivatives by N,N'-dibenzylated S,S-(+)-tetrandrine. Organic & biomolecular chemistry. vol 2. issue 12. 2004-08-31. PMID:15188038. |
complexation of free and n-acetylated alpha-amino acid anions (gly, ala, phe) and some structurally related guests by a dicationic cyclophane-type n,n'-dibenzylated chiral derivative of a bisisoquinoline macrocyclic alkaloid s,s-(+)-tetrandrine (dbt) has been studied by (1)h-nmr titrations in d(2)o. |
2004-08-31 |
2023-08-12 |
Not clear |