| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sriraman Damodaran, John R Cressman, Zbigniew Jedrzejewski-Szmek, Kim T Blackwel. Desynchronization of fast-spiking interneurons reduces β-band oscillations and imbalance in firing in the dopamine-depleted striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 3. 2015-03-24. PMID:25609629. |
here we use a computational network model of medium spiny neurons (msns)-fast-spiking interneurons (fsis), based on data from several mammalian species, and find that robust β-band oscillations and imbalanced firing emerge from implementation of changes to cellular and circuit properties caused by dopamine depletion. |
2015-03-24 |
2023-08-13 |
Not clear |
| Jodi E Gresack, Patricia A Seymour, Christopher J Schmidt, Victoria B Risbroug. Inhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating. Psychopharmacology. vol 231. issue 10. 2015-02-21. PMID:24363077. |
inhibitors of phosphodiesterase 10a (pde10a), an enzyme highly expressed in medium spiny neurons of the mammalian striatum, enhance activity in direct (dopamine d1 receptor-expressing) and indirect (d2 receptor-expressing striatal output) pathways. |
2015-02-21 |
2023-08-12 |
Not clear |
| Pamela F Marcott, Aphroditi A Mamaligas, Christopher P For. Phasic dopamine release drives rapid activation of striatal D2-receptors. Neuron. vol 84. issue 1. 2015-02-20. PMID:25242218. |
medium spiny neurons (msns) are a major target of dopamine in the striatum. |
2015-02-20 |
2023-08-13 |
Not clear |
| Jingping Zhang, Taixiang Saur, Angela N Duke, Seth G N Grant, Donna M Platt, James K Rowlett, Ole Isacson, Wei-Dong Ya. Motor impairments, striatal degeneration, and altered dopamine-glutamate interplay in mice lacking PSD-95. Journal of neurogenetics. vol 28. issue 1-2. 2015-01-07. PMID:24702501. |
excessive activation of the n-methyl-d-aspartate (nmda) receptor and the neurotransmitter dopamine (da) mediate neurotoxicity and neurodegeneration under many neurological conditions, including huntington's disease (hd), an autosomal dominant neurodegenerative disease characterized by the preferential loss of medium spiny projection neurons (msns) in the striatum. |
2015-01-07 |
2023-08-13 |
mouse |
| Liming Zhang, Poulomee Bose, Richard A Warre. Dopamine preferentially inhibits NMDA receptor-mediated EPSCs by acting on presynaptic D1 receptors in nucleus accumbens during postnatal development. PloS one. vol 9. issue 5. 2014-12-18. PMID:24784836. |
nucleus accumbens (nacb), a major site of action of drugs of abuse and dopamine (da) signalling in msns (medium spiny neurons), is critically involved in mediating behavioural responses of drug addiction. |
2014-12-18 |
2023-08-13 |
rat |
| Liming Zhang, Poulomee Bose, Richard A Warre. Dopamine preferentially inhibits NMDA receptor-mediated EPSCs by acting on presynaptic D1 receptors in nucleus accumbens during postnatal development. PloS one. vol 9. issue 5. 2014-12-18. PMID:24784836. |
in this study we attempted to characterize the effects of dopamine (da) on evoked glutamatergic excitatory postsynaptic currents (epscs) in nacb medium spiny (ms) neurons in 1 to 21 day-old rat pups. |
2014-12-18 |
2023-08-13 |
rat |
| Omar Gutierrez-Arenas, Olivia Eriksson, Jeanette Hellgren Kotalesk. Segregation and crosstalk of D1 receptor-mediated activation of ERK in striatal medium spiny neurons upon acute administration of psychostimulants. PLoS computational biology. vol 10. issue 1. 2014-11-12. PMID:24499932. |
the convergence of corticostriatal glutamate and dopamine from the midbrain in the striatal medium spiny neurons (msn) triggers synaptic plasticity that underlies reinforcement learning and pathological conditions such as psychostimulant addiction. |
2014-11-12 |
2023-08-12 |
Not clear |
| Shelly Sooyun Song, Byeong Jun Kang, Lei Wen, Hyo Jin Lee, Hye-Ri Sim, Tae Hyong Kim, Sehyoun Yoon, Bong-June Yoon, George J Augustine, Ja-Hyun Bai. Optogenetics reveals a role for accumbal medium spiny neurons expressing dopamine D2 receptors in cocaine-induced behavioral sensitization. Frontiers in behavioral neuroscience. vol 8. 2014-10-29. PMID:25352792. |
optogenetics reveals a role for accumbal medium spiny neurons expressing dopamine d2 receptors in cocaine-induced behavioral sensitization. |
2014-10-29 |
2023-08-13 |
mouse |
| Shelly Sooyun Song, Byeong Jun Kang, Lei Wen, Hyo Jin Lee, Hye-Ri Sim, Tae Hyong Kim, Sehyoun Yoon, Bong-June Yoon, George J Augustine, Ja-Hyun Bai. Optogenetics reveals a role for accumbal medium spiny neurons expressing dopamine D2 receptors in cocaine-induced behavioral sensitization. Frontiers in behavioral neuroscience. vol 8. 2014-10-29. PMID:25352792. |
here we have used an optogenetic approach to examine the role of nac medium spiny neurons (msns) expressing dopamine d2 receptors (d2rs) in cocaine-induced behavioral sensitization. |
2014-10-29 |
2023-08-13 |
mouse |
| Sho Yagishita, Akiko Hayashi-Takagi, Graham C R Ellis-Davies, Hidetoshi Urakubo, Shin Ishii, Haruo Kasa. A critical time window for dopamine actions on the structural plasticity of dendritic spines. Science (New York, N.Y.). vol 345. issue 6204. 2014-10-23. PMID:25258080. |
such reward signals are primarily coded by dopamine, which modulates the synaptic connections of medium spiny neurons in the striatum. |
2014-10-23 |
2023-08-13 |
Not clear |
| Geraldine J Kress, Hong-Jin Shu, Andrew Yu, Amanda Taylor, Ann Benz, Steve Harmon, Steven Menneric. Fast phasic release properties of dopamine studied with a channel biosensor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 35. 2014-10-17. PMID:25164674. |
we circumvent these limitations by introducing a dopamine-gated chloride channel into rat dorsal striatal medium spiny neurons, targets of strong dopamine innervation, thereby transforming dopamine from a slow transmitter into a fast transmitter and revealing new opportunities for studying moment-to-moment regulation of dopamine release. |
2014-10-17 |
2023-08-13 |
rat |
| Sriraman Damodaran, Rebekah C Evans, Kim T Blackwel. Synchronized firing of fast-spiking interneurons is critical to maintain balanced firing between direct and indirect pathway neurons of the striatum. Journal of neurophysiology. vol 111. issue 4. 2014-09-30. PMID:24304860. |
altered firing in the globus pallidus suggests that striatal medium spiny neurons (msn) of the direct (d1 msn) and indirect pathway (d2 msn) are imbalanced during dopamine depletion. |
2014-09-30 |
2023-08-12 |
Not clear |
| William A Toy, Giselle M Petzinger, Brian J Leyshon, Garnik K Akopian, John P Walsh, Matilde V Hoffman, Marta G Vučković, Michael W Jakowe. Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease. Neurobiology of disease. vol 63. 2014-09-19. PMID:24316165. |
striatal medium spiny neurons (msns) can be delineated into two populations, the dopamine d1 receptor (da-d1r)-containing msns of the direct pathway and dopamine d2 receptor (da-d2r)-containing msns of the indirect pathway. |
2014-09-19 |
2023-08-12 |
mouse |
| Yan Kong, Zhuan Xu, Wan-li Dong, Xiu-ying Cai, Xiao-yu Duan, Bi-yin Ca. [Effects of endogenous dopamine on two-state voltage oscillations of striatum medium spiny neurons]. Zhonghua yi xue za zhi. vol 93. issue 43. 2014-09-15. PMID:24423915. |
[effects of endogenous dopamine on two-state voltage oscillations of striatum medium spiny neurons]. |
2014-09-15 |
2023-08-12 |
Not clear |
| Yan Kong, Zhuan Xu, Wan-li Dong, Xiu-ying Cai, Xiao-yu Duan, Bi-yin Ca. [Effects of endogenous dopamine on two-state voltage oscillations of striatum medium spiny neurons]. Zhonghua yi xue za zhi. vol 93. issue 43. 2014-09-15. PMID:24423915. |
to explore the effects of endogenous dopamine (da) on striatum medium spiny neurons (msns) in acute brain slices by the means of electrophysiology and elucidate the impact of nigrostriatal circuit loop on the functional status of msns. |
2014-09-15 |
2023-08-12 |
Not clear |
| Matthieu F Bastide, Sandra Dovero, Giselle Charron, Gregory Porras, Christian E Gross, Pierre-Olivier Fernagut, Erwan Bézar. Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia. Neurobiology of disease. vol 62. 2014-09-03. PMID:24103779. |
long-term l-3,4-dihydroxyphenylalanine (l-dopa) treatment in parkinson's disease (pd) leads to l-dopa-induced dyskinesia (lid), a condition thought to primarily involve the dopamine d1 receptor-expressing striatal medium spiny neurons. |
2014-09-03 |
2023-08-12 |
rat |
| S Recillas-Morales, L Sánchez-Vega, N Ochoa-Sánchez, I Caballero-Florán, F Paz-Bermúdez, I Silva, J Aceves, D Erlij, B Florá. L-type Ca²⁺ channel activity determines modulation of GABA release by dopamine in the substantia nigra reticulata and the globus pallidus of the rat. Neuroscience. vol 256. 2014-08-27. PMID:24505607. |
modulation of l-type ca²⁺-channel function by dopamine is a major determinant of the rate of action potential firing by striatal medium spiny neurons. |
2014-08-27 |
2023-08-12 |
rat |
| Wei Wei, Li Li, Guoliang Yu, Shengyuan Ding, Chengyao Li, Fu-Ming Zho. Supersensitive presynaptic dopamine D2 receptor inhibition of the striatopallidal projection in nigrostriatal dopamine-deficient mice. Journal of neurophysiology. vol 110. issue 9. 2014-06-20. PMID:23945778. |
the dopamine (da) d2 receptor (d2r)-expressing medium spiny neurons (d2-msns) in the striatum project to and inhibit the gabaergic neurons in the globus pallidus (gp), forming an important link in the indirect pathway of the basal ganglia movement control circuit. |
2014-06-20 |
2023-08-12 |
mouse |
| Linghai Yang, Merle L Gilbert, Ruimao Zheng, G Stanley McKnigh. Selective expression of a dominant-negative type Iα PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 14. 2014-05-22. PMID:24695708. |
striatal medium spiny neurons (msns) mediate many of the physiological effects of dopamine, including the regulation of feeding and motor behaviors. |
2014-05-22 |
2023-08-13 |
mouse |
| Alfonso Alfaro-Rodriguez, María Alonso-Spilsbury, Emilio Arch-Tirado, Rigoberto Gonzalez-Pina, José-Antonio Arias-Montaño, Antonio Bueno-Nav. Histamine H3 receptor activation prevents dopamine D1 receptor-mediated inhibition of dopamine release in the rat striatum: a microdialysis study. Neuroscience letters. vol 552. 2014-05-15. PMID:23896530. |
histamine h3 receptors (h3rs) co-localize with dopamine (da) d1 receptors (d1rs) on striatal medium spiny neurons and functionally antagonize d1r-mediated responses. |
2014-05-15 |
2023-08-12 |
rat |