Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kuldip D Dave, John A Harvey, Vincent J Aloy. The time-course for up- and down-regulation of the cortical 5-hydroxytryptamine (5-HT)2A receptor density predicts 5-HT2A receptor-mediated behavior in the rabbit. The Journal of pharmacology and experimental therapeutics. vol 323. issue 1. 2007-11-05. PMID:17640952. |
the time-course for up- and down-regulation of the cortical 5-hydroxytryptamine (5-ht)2a receptor density predicts 5-ht2a receptor-mediated behavior in the rabbit. |
2007-11-05 |
2023-08-12 |
rabbit |
Kuldip D Dave, John A Harvey, Vincent J Aloy. The time-course for up- and down-regulation of the cortical 5-hydroxytryptamine (5-HT)2A receptor density predicts 5-HT2A receptor-mediated behavior in the rabbit. The Journal of pharmacology and experimental therapeutics. vol 323. issue 1. 2007-11-05. PMID:17640952. |
5-hydroxytryptamine (serotonin; 5-ht)2 receptor agonists such as (+/-)-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (doi) injected systemically or directly into frontal cortex, elicit stereotyped head movements that are mediated by 5-ht2a receptors. |
2007-11-05 |
2023-08-12 |
rabbit |
Alexandre O Fernandes da Silva, Luciane H Gargaglioni, Luiz G S Branc. 5-HT2A serotoninergic receptor in the locus coeruleus participates in the first phase of lipopolysaccharide-induced fever. Canadian journal of physiology and pharmacology. vol 85. issue 5. 2007-10-30. PMID:17632583. |
taken together, these results indicate that serotonin acting on 5-ht2a receptors in the lc mediates the first phase of the febrile response, whereas 5-ht1a receptors are not involved in the lipopolysaccharide-induced fever. |
2007-10-30 |
2023-08-12 |
Not clear |
Magdalena Zaniewska, Andrew C McCreary, Edmund Przegaliński, Malgorzata Fili. Effects of the serotonin 5-HT2A and 5-HT2C receptor ligands on the discriminative stimulus effects of nicotine in rats. European journal of pharmacology. vol 571. issue 2-3. 2007-10-25. PMID:17617403. |
effects of the serotonin 5-ht2a and 5-ht2c receptor ligands on the discriminative stimulus effects of nicotine in rats. |
2007-10-25 |
2023-08-12 |
rat |
Magdalena Zaniewska, Andrew C McCreary, Edmund Przegaliński, Malgorzata Fili. Effects of the serotonin 5-HT2A and 5-HT2C receptor ligands on the discriminative stimulus effects of nicotine in rats. European journal of pharmacology. vol 571. issue 2-3. 2007-10-25. PMID:17617403. |
the present study tested the hypothesis that serotonergic (5-ht) 5-ht2a or 5-ht2c receptors or their pharmacological stimulation modulated the discriminative stimulus effects of nicotine in male wistar rats. |
2007-10-25 |
2023-08-12 |
rat |
Lorenzo Kiferle, Roberto Ceravolo, Lucia Petrozzi, Carlo Rossi, Daniela Frosini, Anna Rocchi, Gabriele Siciliano, Ubaldo Bonuccelli, Luigi Murr. Visual hallucinations in Parkinson's disease are not influenced by polymorphisms of serotonin 5-HT2A receptor and transporter genes. Neuroscience letters. vol 422. issue 3. 2007-10-23. PMID:17614196. |
visual hallucinations in parkinson's disease are not influenced by polymorphisms of serotonin 5-ht2a receptor and transporter genes. |
2007-10-23 |
2023-08-12 |
Not clear |
Lorenzo Kiferle, Roberto Ceravolo, Lucia Petrozzi, Carlo Rossi, Daniela Frosini, Anna Rocchi, Gabriele Siciliano, Ubaldo Bonuccelli, Luigi Murr. Visual hallucinations in Parkinson's disease are not influenced by polymorphisms of serotonin 5-HT2A receptor and transporter genes. Neuroscience letters. vol 422. issue 3. 2007-10-23. PMID:17614196. |
the association of a serotonin transporter gene-linked polymorphic region (5-httlpr) and the 5-ht2a receptor t102c polymorphism with psychosis in a group of patients with pd was investigated. |
2007-10-23 |
2023-08-12 |
Not clear |
P Heiser, A Dempfle, S Friedel, K Konrad, A Hinney, H Kiefl, S Walitza, T Bettecken, K Saar, M Linder, A Warnke, B Herpertz-Dahlmann, H Schäfer, H Remschmidt, J Hebebran. Family-based association study of serotonergic candidate genes and attention-deficit/hyperactivity disorder in a German sample. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 4. 2007-10-04. PMID:17093889. |
the aim of this study was to investigate seven genetic variants in three genes (serotonin transporter (5-htt), serotonin receptor 1b (5-htr1b) and serotonin receptor 2a (5-htr2a)), which have previously been shown to be associated with adhd. |
2007-10-04 |
2023-08-12 |
Not clear |
F M Theisen, M Haberhausen, M A Firnges, P Gregory, J H Reinders, H Remschmidt, J Hebebrand, J Ante. No evidence for binding of clozapine, olanzapine and/or haloperidol to selected receptors involved in body weight regulation. The pharmacogenomics journal. vol 7. issue 4. 2007-09-27. PMID:16983399. |
with respect to other candidates from (neuro)transmitter systems already suggested to be involved in ap-induced weight gain, the binding profile of olanzapine resembled that of clozapine, with high affinity (ki<10 nm) for serotonin (5-ht) 5-ht2a, 5-ht2c and 5-ht6, muscarinic m1 and histamine h1 receptors. |
2007-09-27 |
2023-08-12 |
Not clear |
D J Sanger, C Soubrane, B Scatto. New perspectives for the treatment of disorders of sleep and arousal. Annales pharmaceutiques francaises. vol 65. issue 4. 2007-09-18. PMID:17652996. |
in the case of the 5ht2a subtype of serotonin receptors, several molecules which improve sleep maintenance and modify sleep architecture by increasing slow wave sleep are currently being tested (eg eplivanserin). |
2007-09-18 |
2023-08-12 |
Not clear |
Valérie Kayser, Iskander Elfihri Elfassi, Bertrand Aubel, Maxette Melfort, David Julius, Jay A Gingrich, Michel Hamon, Sylvie Bourgoi. Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A-/-, 5-HT1B-/-, 5-HT2A-/-, 5-HT3A-/- and 5-HTT-/- knock-out male mice. Pain. vol 130. issue 3. 2007-08-09. PMID:17250964. |
pain behaviors of mutants which do not express 5-ht1a, 5-ht1b, 5-ht2a or 5-ht3a receptors, or lacking the 5-ht transporter, compared to paired wild-type mice of the same genetic background, were examined using validated tests based on different sensory modalities. |
2007-08-09 |
2023-08-12 |
mouse |
Tamara Y Minosyan, Rong Lu, Mansoureh Eghbali, Ligia Toro, Enrico Stefan. Increased 5-HT contractile response in late pregnant rat myometrium is associated with a higher density of 5-HT2A receptors. The Journal of physiology. vol 581. issue Pt 1. 2007-07-23. PMID:17395633. |
increased 5-ht contractile response in late pregnant rat myometrium is associated with a higher density of 5-ht2a receptors. |
2007-07-23 |
2023-08-12 |
rat |
Kevin M Malone, Steven P Ellis, Dianne Currier, J John Man. Platelet 5-HT2A receptor subresponsivity and lethality of attempted suicide in depressed in-patients. The international journal of neuropsychopharmacology. vol 10. issue 3. 2007-07-20. PMID:16893479. |
we have previously reported greater platelet 5-ht2a receptor density, and impaired serotonin enhancement of adp-induced platelet aggregation, an indirect measure of signal transduction, in high-lethality suicide attempters. |
2007-07-20 |
2023-08-12 |
Not clear |
Kevin M Malone, Steven P Ellis, Dianne Currier, J John Man. Platelet 5-HT2A receptor subresponsivity and lethality of attempted suicide in depressed in-patients. The international journal of neuropsychopharmacology. vol 10. issue 3. 2007-07-20. PMID:16893479. |
we hypothesized that serotonin-activated phosphoinositide (pi) hydrolysis, a direct measure of platelet serotonin 5-ht2a receptor responsivity would be lower in depressed high-lethality suicide attempters. |
2007-07-20 |
2023-08-12 |
Not clear |
Vincenzo De Luca, Olga Likhodi, James L Kennedy, Albert H C Won. Differential expression and parent-of-origin effect of the 5-HT2A receptor gene C102T polymorphism: analysis of suicidality in schizophrenia and bipolar disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 3. 2007-07-18. PMID:17221840. |
the serotonin 2a (5-ht2a) receptor gene has been implicated in the pathogenesis of suicidal behavior by a genetic association between the 5-ht2a c102t silent polymorphism and suicidality in patients with major depression. |
2007-07-18 |
2023-08-12 |
human |
Moti L Chapagain, Saguna Verma, Frederic Mercier, Richard Yanagihara, Vivek R Nerurka. Polyomavirus JC infects human brain microvascular endothelial cells independent of serotonin receptor 2A. Virology. vol 364. issue 1. 2007-07-18. PMID:17399760. |
hbmve cells in vitro did not express serotonin receptor 2a (5ht(2a)r), and 5ht(2a)r blockers did not prevent jcv infection of hbmve cells. |
2007-07-18 |
2023-08-12 |
human |
Pilar A Sáiz, M Paz García-Portilla, Celso Arango, Blanca Morales, Victoria Alvarez, Eliécer Coto, Juan M Fernández, M Teresa Bascarán, Manuel Bousoño, Julio Bobe. Association study of serotonin 2A receptor (5-HT2A) and serotonin transporter (5-HTT) gene polymorphisms with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 3. 2007-06-26. PMID:17291660. |
association study of serotonin 2a receptor (5-ht2a) and serotonin transporter (5-htt) gene polymorphisms with schizophrenia. |
2007-06-26 |
2023-08-12 |
Not clear |
Pilar A Sáiz, M Paz García-Portilla, Celso Arango, Blanca Morales, Victoria Alvarez, Eliécer Coto, Juan M Fernández, M Teresa Bascarán, Manuel Bousoño, Julio Bobe. Association study of serotonin 2A receptor (5-HT2A) and serotonin transporter (5-HTT) gene polymorphisms with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 3. 2007-06-26. PMID:17291660. |
to investigate (i) the association between four serotonergic polymorphisms (a-1438g and t102c of the 5-ht2a receptor gene, and 5-htt vntr and 5-httlpr of the 5-ht transporter gene) and schizophrenia and (ii) the potential interaction of those polymorphisms in the development of schizophrenia. |
2007-06-26 |
2023-08-12 |
Not clear |
Chen Xu, François Giuliano, X Q Sun, Marie-Jeanne Brisorgueil, Patrick Leclerc, Daniel Vergé, Marie Conrat. Serotonin 5-HT2A and 5-HT5A receptors are expressed by different motoneuron populations in rat Onuf's nucleus. The Journal of comparative neurology. vol 502. issue 4. 2007-06-21. PMID:17394137. |
serotonin 5-ht2a and 5-ht5a receptors are expressed by different motoneuron populations in rat onuf's nucleus. |
2007-06-21 |
2023-08-12 |
rat |
Chen Xu, François Giuliano, X Q Sun, Marie-Jeanne Brisorgueil, Patrick Leclerc, Daniel Vergé, Marie Conrat. Serotonin 5-HT2A and 5-HT5A receptors are expressed by different motoneuron populations in rat Onuf's nucleus. The Journal of comparative neurology. vol 502. issue 4. 2007-06-21. PMID:17394137. |
in addition, the subcellular distribution of receptors suggests a different mode of action of 5-ht, paracrine at 5-ht2a receptors and synaptic at 5-ht5a receptors. |
2007-06-21 |
2023-08-12 |
rat |