| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Harumi Hotta, Fusako Kagitani, Masahiro Kondo, Sae Uchid. Basal forebrain stimulation induces NGF secretion in ipsilateral parietal cortex via nicotinic receptor activation in adult, but not aged rats. Neuroscience research. vol 63. issue 2. 2009-03-17. PMID:19059440. |
the role of cholinergic basal forebrain inputs to cerebral cortex in regulating regional nerve growth factor (ngf) secretion was examined in adult (4-6 months) and aged (29-31 months) rats. |
2009-03-17 |
2023-08-12 |
rat |
| Harumi Hotta, Fusako Kagitani, Masahiro Kondo, Sae Uchid. Basal forebrain stimulation induces NGF secretion in ipsilateral parietal cortex via nicotinic receptor activation in adult, but not aged rats. Neuroscience research. vol 63. issue 2. 2009-03-17. PMID:19059440. |
we conclude that cholinergic inputs to neocortex mediate ngf secretion by cortical neurons via nicotinic receptors. |
2009-03-17 |
2023-08-12 |
rat |
| Kalpana Barhwal, Sunil Kumar Hota, Dipti Prasad, Shashi Bala Singh, G Ilavazhaga. Hypoxia-induced deactivation of NGF-mediated ERK1/2 signaling in hippocampal cells: neuroprotection by acetyl-L-carnitine. Journal of neuroscience research. vol 86. issue 12. 2009-03-16. PMID:18500755. |
alcar therefore provides neuroprotection by stabilizing mitochondrial membrane, restoring the cholinergic transmission, and more importantly, it stimulates ngf receptors, thus triggering cell survival pathway via erk phosphorylation. |
2009-03-16 |
2023-08-12 |
Not clear |
| Elin Larsson, Regina Kuma, Anna Norberg, Jan Minde, Monica Holmber. Nerve growth factor R221W responsible for insensitivity to pain is defectively processed and accumulates as proNGF. Neurobiology of disease. vol 33. issue 2. 2009-03-09. PMID:19038341. |
ngf is important not only for the survival of sensory neurons but also for the sympathetic neurons and cholinergic neurons of the basal forebrain; however, it is the sensory neurons that are mainly affected in patients with mutant ngfb. |
2009-03-09 |
2023-08-12 |
Not clear |
| K Tujioka, X Shi, M Ohsumi, T Tuchiya, K Hayase, T Uchida, S Ikeda, A Morishita, H Yokogosh. Effect of quantity and quality of dietary protein on choline acetyltransferase and nerve growth factor, and their mRNAs in the cerebral cortex and hippocampus of rats. Amino acids. vol 36. issue 1. 2009-03-02. PMID:18188665. |
the brain protein synthesis is sensitive to the dietary protein; however, the role of dietary protein on biomarkers including choline acetyltransferase and nerve growth factor (ngf) for the function of cholinergic neurons remains unknown in young rats. |
2009-03-02 |
2023-08-12 |
rat |
| Elliott J Mufson, Scott E Counts, Sylvia E Perez, Stephen D Ginsber. Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert review of neurotherapeutics. vol 8. issue 11. 2009-02-20. PMID:18986241. |
a ngf gene therapy trial reduced cognitive decline and stimulated cholinergic fiber growth in humans with mild ad. |
2009-02-20 |
2023-08-12 |
Not clear |
| Josef Marksteiner, Michael Pirchl, Celine Ullrich, Harald Oberbauer, Imrich Blasko, Wolfgang Lederer, Hartmann Hinterhuber, Christian Humpe. Analysis of cerebrospinal fluid of Alzheimer patients. Biomarkers and toxic properties. Pharmacology. vol 82. issue 3. 2009-01-02. PMID:18810245. |
using a bioassay of brain slices, we showed that recombinant mature ngf enhanced survival of cholinergic neurons, while wild-type human pro-ngf displayed a less pronounced effect. |
2009-01-02 |
2023-08-12 |
human |
| Beata Madziar, Sonia Shah, Martina Brock, Rebecca Burke, Ignacio Lopez-Coviella, Ann-Christin Nickel, Esra Betul Cakal, Jan Krzysztof Blusztajn, Brygida Bers. Nerve growth factor regulates the expression of the cholinergic locus and the high-affinity choline transporter via the Akt/PKB signaling pathway. Journal of neurochemistry. vol 107. issue 5. 2008-12-24. PMID:18793330. |
nerve growth factor (ngf) is a trophic and survival factor for cholinergic neurons, and it induces the expression of several genes that are essential for synthesis and storage of acetylcholine (ach), specifically choline acetyltransferase, vesicular ach transporter (vacht), and choline transporter. |
2008-12-24 |
2023-08-12 |
mouse |
| Antonino Cattaneo, Simona Capsoni, Francesca Paolett. Towards non invasive nerve growth factor therapies for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 15. issue 2. 2008-12-16. PMID:18953113. |
in the past thirty years, nerve growth factor (ngf) has received much attention for its potential role as a therapeutic agent for alzheimer's disease (ad) due to its neurotrophic activities on basal forebrain cholinergic neurons. |
2008-12-16 |
2023-08-12 |
human |
| Neal Prakash, Ron D Frosti. What has intrinsic signal optical imaging taught us about NGF-induced rapid plasticity in adult cortex and its relationship to the cholinergic system? Molecular imaging and biology. vol 7. issue 1. 2008-10-10. PMID:15912271. |
in particular, it appears that acetylcholine (ach), nicotinic ach receptors, nerve growth factor (ngf), and ngf receptors (trka and p75) are involved in an important feedback loop between the basal forebrain cholinergic system (bfcs) and the neocortex. |
2008-10-10 |
2023-08-12 |
Not clear |
| Kathie M Bishop, Eva K Hofer, Arpesh Mehta, Anthony Ramirez, Liangwu Sun, Mark Tuszynski, Raymond T Bartu. Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439998. |
therapeutic potential of cere-110 (aav2-ngf): targeted, stable, and sustained ngf delivery and trophic activity on rodent basal forebrain cholinergic neurons. |
2008-07-07 |
2023-08-12 |
human |
| Kathie M Bishop, Eva K Hofer, Arpesh Mehta, Anthony Ramirez, Liangwu Sun, Mark Tuszynski, Raymond T Bartu. Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439998. |
treatment of degenerating basal forebrain cholinergic neurons with nerve growth factor (ngf) in alzheimer's disease has long been contemplated, but an effective and safe delivery method has been lacking. |
2008-07-07 |
2023-08-12 |
human |
| S K Kidd, D W Anderson, J S Schneide. Postnatal lead exposure alters expression of forebrain p75 and TrkA nerve growth factor receptors. Brain research. vol 1195. 2008-05-27. PMID:18191823. |
the hippocampus and striatum are among the areas particularly sensitive to the effects of lead and cholinergic neurons in both regions depend upon nerve growth factor (ngf) for their survival and maturation. |
2008-05-27 |
2023-08-12 |
rat |
| Ahmad Salehi, Mehrdad Faizi, Pavel V Belichenko, William C Moble. Using mouse models to explore genotype-phenotype relationship in Down syndrome. Mental retardation and developmental disabilities research reviews. vol 13. issue 3. 2008-04-11. PMID:17910089. |
we found that increased dosage of the gene for app is linked to failed ngf signaling and cholinergic neurodegeneration in a mouse model of ds. |
2008-04-11 |
2023-08-12 |
mouse |
| A V Terry, D A Gearhart, S Warner, E J Hohnadel, M-L Middlemore, G Zhang, M G Bartlett, S P Mahadi. Protracted effects of chronic oral haloperidol and risperidone on nerve growth factor, cholinergic neurons, and spatial reference learning in rats. Neuroscience. vol 150. issue 2. 2008-04-03. PMID:17942237. |
drug effects on learning and memory and important neurobiological substrates of memory, the neurotrophin, nerve growth factor (ngf) and its receptors, and certain components of the basal forebrain cholinergic system were investigated. |
2008-04-03 |
2023-08-12 |
human |
| Veronica Di Fausto, Marco Fiore, Paola Tirassa, Alessandro Lambiase, Luigi Alo. Eye drop NGF administration promotes the recovery of chemically injured cholinergic neurons of adult mouse forebrain. The European journal of neuroscience. vol 26. issue 9. 2008-03-14. PMID:17970722. |
eye drop ngf administration promotes the recovery of chemically injured cholinergic neurons of adult mouse forebrain. |
2008-03-14 |
2023-08-12 |
mouse |
| Veronica Di Fausto, Marco Fiore, Paola Tirassa, Alessandro Lambiase, Luigi Alo. Eye drop NGF administration promotes the recovery of chemically injured cholinergic neurons of adult mouse forebrain. The European journal of neuroscience. vol 26. issue 9. 2008-03-14. PMID:17970722. |
in the present study, we investigated whether ngf application as collyrium can promote the recovery of chemically injured basal forebrain cholinergic neurons. |
2008-03-14 |
2023-08-12 |
mouse |
| K Schindowski, K Belarbi, L Bué. Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes, brain, and behavior. vol 7 Suppl 1. 2008-03-12. PMID:18184369. |
nerve growth factor (ngf), for instance, is produced in the neocortex and the hippocampus and then retrogradely transported to the cholinergic neurons of the basal forebrain. |
2008-03-12 |
2023-08-12 |
Not clear |
| Carey Y L Huh, Marc Danik, Frédéric Manseau, Louis-Eric Trudeau, Sylvain William. Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256260. |
although it is well known that nerve growth factor (ngf) promotes synaptic function of cholinergic basal forebrain neurons, how ngf affects the newly identified basal forebrain neurons remains undetermined. |
2008-02-25 |
2023-08-12 |
rat |
| Carey Y L Huh, Marc Danik, Frédéric Manseau, Louis-Eric Trudeau, Sylvain William. Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of Broca via mechanisms mediated by p75NTR. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 6. 2008-02-25. PMID:18256260. |
we found that chronic exposure to ngf significantly increased acetylcholine and glutamate release from cholinergic ms-dbb neurons, whereas glutamate and gaba transmission from noncholinergic ms-dbb neurons were not affected by ngf. |
2008-02-25 |
2023-08-12 |
rat |