| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Morgane Chiesa, Romain Nardou, Natalia Lozovaya, Sanaz Eftekhari, Roman Tyzio, Damien Guimond, Diana C Ferrari, Yehezkel Ben-Ar. Enhanced Glutamatergic Currents at Birth in Shank3 KO Mice. Neural plasticity. vol 2019. 2020-07-27. PMID:31354805. |
maternal treatment around birth with bumetanide restored the gaba developmental sequence and attenuated the autism pathogenesis in offspring. |
2020-07-27 |
2023-08-13 |
mouse |
| Allison M J Anacker, Jacqueline T Moran, Sara Santarelli, C Gunnar Forsberg, Tiffany D Rogers, Gregg D Stanwood, Benjamin J Hall, Eric Delpire, Jeremy Veenstra-VanderWeele, Michael D Sax. Enhanced Social Dominance and Altered Neuronal Excitability in the Prefrontal Cortex of Male KCC2b Mutant Mice. Autism research : official journal of the International Society for Autism Research. vol 12. issue 5. 2020-07-06. PMID:30977597. |
the k-cl cotransporter kcc2 is essential in the development of the "gaba switch" that produces a change in neuronal responses to gaba signaling from excitatory to inhibitory early in brain development, and alterations in this progression have previously been hypothesized to play a causal role in autism spectrum disorder (asd). |
2020-07-06 |
2023-08-13 |
mouse |
| Mahshid Fattahi, Ata Bushehri, Afagh Alavi, Vahid Asghariazar, Ahoura Nozari, Saghar Ghasemi Firouzabadi, Parisa Motamedian Dehkordi, Marzieh Javid, Saeed Farajzadeh Valiliou, Javad Karimian, Farkhondeh Behjat. Bi-allelic Mutations in ALDH5A1 is associated with succinic semialdehyde dehydrogenase deficiency and severe intellectual disability. Gene. 2020-07-04. PMID:32621952. |
ssadhd, succinic semialdehyde dehydrogenase deficiency; gaba, gamma-aminobutyric acid; aldh5a1, aldehyde dehydrogenase 5 family member a1; ghb, γ -hydroxybutyrate; ssa, succinic semi aldehyde; wisc, wechsler intelligence scale for children; cns, central nervous system ; eeg, electroencephalography; eeef, empirical effective energy functions; asd, autism spectrum disorder; adhd, attention deficit hyperactivity disorder; iq, intelligence quotient; emg, electromyography; ncv, nerve conduction velocity; cp, cerebral palsy. |
2020-07-04 |
2023-08-13 |
Not clear |
| Maya A Rhine, Jennifer M Parrott, Maria N Schultz, Tatiana M Kazdoba, Jacqueline N Crawle. Hypothesis-driven investigations of diverse pharmacological targets in two mouse models of autism. Autism research : official journal of the International Society for Autism Research. vol 12. issue 3. 2020-04-17. PMID:30653853. |
gaba agonists present opportunities for personalized interventions to treat components of autism spectrum disorder. |
2020-04-17 |
2023-08-13 |
mouse |
| Laurie-Anne Sapey-Triomphe, Franck Lamberton, Sandrine Sonié, Jérémie Mattout, Christina Schmit. Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism. Autism research : official journal of the International Society for Autism Research. vol 12. issue 4. 2020-04-03. PMID:30632707. |
tactile hypersensitivity and gaba concentration in the sensorimotor cortex of adults with autism. |
2020-04-03 |
2023-08-13 |
Not clear |
| Elisabeth Fernel. Further studies of GABA and Glutamate imbalances in autism are important challenges for future research. Acta paediatrica (Oslo, Norway : 1992). vol 108. issue 2. 2019-12-06. PMID:30359475. |
further studies of gaba and glutamate imbalances in autism are important challenges for future research. |
2019-12-06 |
2023-08-13 |
Not clear |
| Priyanka Purkayastha, Aruna Malapati, Perumal Yogeeswari, Dharmarajan Srira. A Review on GABA/Glutamate Pathway for Therapeutic Intervention of ASD and ADHD Current medicinal chemistry. vol 22. issue 15. 2019-11-20. PMID:25666800. |
several evidences implicated relative loss of inhibitory gaba with corresponding glutamate mediated hyper-excitation in development of autism spectrum disorder (asd) and attention deficit hyperactivity disorder (adhd). |
2019-11-20 |
2023-08-13 |
Not clear |
| Marianna K Keaveney, Hua-An Tseng, Tina L Ta, Howard J Gritton, Heng-Ye Man, Xue Ha. A MicroRNA-Based Gene-Targeting Tool for Virally Labeling Interneurons in the Rodent Cortex. Cell reports. vol 24. issue 2. 2019-11-07. PMID:29996091. |
our interneuron-targeting, microrna-guided neuron tag, "gaba magnet," achieves >95% interneuron selective labeling in the mouse cortex, including in a murine model of autism and also some preferential labeling of interneurons in the rat brain. |
2019-11-07 |
2023-08-13 |
mouse |
| Chenshuang Li, Zhong Zheng, Pin Ha, Xiaoyan Chen, Wenlu Jiang, Shan Sun, Feng Chen, Greg Asatrian, Emily A Berthiaume, Jong Kil Kim, Eric C Chen, Shen Pang, Xinli Zhang, Kang Ting, Chia So. Neurexin Superfamily Cell Membrane Receptor Contactin-Associated Protein Like-4 (Cntnap4) Is Involved in Neural EGFL-Like 1 (Nell-1)-Responsive Osteogenesis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 33. issue 10. 2019-10-25. PMID:29905970. |
cntnap4 knockout mice display decreased presynaptic gamma-aminobutyric acid (gaba) and increased dopamine release that is associated with severe, highly penetrant, repetitive, and perseverative movements commonly found in human autism spectrum disorder patients. |
2019-10-25 |
2023-08-13 |
mouse |
| Oliver D Howes, Maria Rogdaki, James L Findon, Robert H Wichers, Tony Charman, Bryan H King, Eva Loth, Gráinne M McAlonan, James T McCracken, Jeremy R Parr, Carol Povey, Paramala Santosh, Simon Wallace, Emily Simonoff, Declan G Murph. Autism spectrum disorder: Consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology. Journal of psychopharmacology (Oxford, England). vol 32. issue 1. 2019-10-14. PMID:29237331. |
the aetiology of autism spectrum disorder involves genetic and environmental contributions, and implicates a number of brain systems, in particular the gamma-aminobutyric acid, serotonergic and glutamatergic systems. |
2019-10-14 |
2023-08-13 |
Not clear |
| Anthony J Griswold, Derek Van Booven, Michael L Cuccaro, Jonathan L Haines, John R Gilbert, Margaret A Pericak-Vanc. Identification of rare noncoding sequence variants in gamma-aminobutyric acid A receptor, alpha 4 subunit in autism spectrum disorder. Neurogenetics. vol 19. issue 1. 2019-10-03. PMID:29151244. |
identification of rare noncoding sequence variants in gamma-aminobutyric acid a receptor, alpha 4 subunit in autism spectrum disorder. |
2019-10-03 |
2023-08-13 |
Not clear |
| Anthony J Griswold, Derek Van Booven, Michael L Cuccaro, Jonathan L Haines, John R Gilbert, Margaret A Pericak-Vanc. Identification of rare noncoding sequence variants in gamma-aminobutyric acid A receptor, alpha 4 subunit in autism spectrum disorder. Neurogenetics. vol 19. issue 1. 2019-10-03. PMID:29151244. |
alterations of the gamma-aminobutyric acid (gaba) signaling system has been strongly linked to the pathophysiology of autism spectrum disorder (asd). |
2019-10-03 |
2023-08-13 |
Not clear |
| Peter Goo. Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). Clinical nutrition ESPEN. vol 23. 2019-05-31. PMID:29460795. |
stress-induced weak androgens and estrogen depletion coherently explain white matter asymmetry and dysconnection in autism, extreme male brain, low brain blood flow, hyperexcitability, social anxiety, and insufficient maternal oxytocin at birth to limit fetal brain chloride/water and mature gaba. |
2019-05-31 |
2023-08-13 |
Not clear |
| Andreia Carvalho Pereira, Inês R Violante, Susana Mouga, Guiomar Oliveira, Miguel Castelo-Branc. Medial Frontal Lobe Neurochemistry in Autism Spectrum Disorder is Marked by Reduced N-Acetylaspartate and Unchanged Gamma-Aminobutyric Acid and Glutamate + Glutamine Levels. Journal of autism and developmental disorders. vol 48. issue 5. 2019-05-27. PMID:29177616. |
medial frontal lobe neurochemistry in autism spectrum disorder is marked by reduced n-acetylaspartate and unchanged gamma-aminobutyric acid and glutamate + glutamine levels. |
2019-05-27 |
2023-08-13 |
Not clear |
| Melissa Kirkovski, Chao Suo, Peter Gregory Enticott, Murat Yücel, Paul Bernard Fitzgeral. Short communication: Sex-linked differences in gamma-aminobutyric acid (GABA) are related to social functioning in autism spectrum disorder. Psychiatry research. Neuroimaging. vol 274. 2019-03-21. PMID:29500101. |
short communication: sex-linked differences in gamma-aminobutyric acid (gaba) are related to social functioning in autism spectrum disorder. |
2019-03-21 |
2023-08-13 |
human |
| Melissa Kirkovski, Chao Suo, Peter Gregory Enticott, Murat Yücel, Paul Bernard Fitzgeral. Short communication: Sex-linked differences in gamma-aminobutyric acid (GABA) are related to social functioning in autism spectrum disorder. Psychiatry research. Neuroimaging. vol 274. 2019-03-21. PMID:29500101. |
magnetic resonance spectroscopy (mrs) was utilized to investigate sex differences in gamma-aminobutyric acid (gaba) between adults with autism spectrum disorder (asd) and neurotypical (nt) controls. |
2019-03-21 |
2023-08-13 |
human |
| Manijeh Mahdavi, Majid Kheirollahi, Roya Riahi, Fariborz Khorvash, Mehdi Khorrami, Maryam Mirsafai. Meta-Analysis of the Association between GABA Receptor Polymorphisms and Autism Spectrum Disorder (ASD). Journal of molecular neuroscience : MN. vol 65. issue 1. 2019-02-18. PMID:29725984. |
meta-analysis of the association between gaba receptor polymorphisms and autism spectrum disorder (asd). |
2019-02-18 |
2023-08-13 |
Not clear |
| Hanoof Al-Otaish, Laila Al-Ayadhi, Geir Bjørklund, Salvatore Chirumbolo, Mauricio A Urbina, Afaf El-Ansar. Relationship between absolute and relative ratios of glutamate, glutamine and GABA and severity of autism spectrum disorder. Metabolic brain disease. vol 33. issue 3. 2019-02-05. PMID:29397522. |
relationship between absolute and relative ratios of glutamate, glutamine and gaba and severity of autism spectrum disorder. |
2019-02-05 |
2023-08-13 |
human |
| Rezvan Noroozi, Mohammad Taheri, Soudeh Ghafouri-Fard, Zeinab Bidel, Mir Davood Omrani, Ali Sanjari Moghaddam, Parisa Sarabi, Alireza Mosavi Jarah. Meta-analysis of GABRB3 Gene Polymorphisms and Susceptibility to Autism Spectrum Disorder. Journal of molecular neuroscience : MN. vol 65. issue 4. 2018-11-08. PMID:30074174. |
several lines of evidence have suggested that the gaba receptor subunit β3 (gabrb3) gene is a genetic contributor in the autism spectrum disorder (asd). |
2018-11-08 |
2023-08-13 |
Not clear |
| A L Ujjainwala, C D Courtney, S G Rhoads, J S Rhodes, C A Christia. Genetic loss of diazepam binding inhibitor in mice impairs social interest. Genes, brain, and behavior. vol 17. issue 5. 2018-10-30. PMID:29193847. |
neuropsychiatric disorders in which reduced social interest is a common symptom, such as autism, depression, and anxiety, are frequently associated with genetic mutations affecting γ-aminobutyric acid (gaba)ergic transmission. |
2018-10-30 |
2023-08-13 |
mouse |